KR102367717B1 - Food composition for relieving hangovers and improving a liver and food containing the same - Google Patents

Abstract

The present invention provides a food composition for relieving hangover and improving the liver function which can increase the effect of relieving hangover symptoms due to excessive drinking, and can effectively alleviate the decrease in the alcoholic liver function, and a health functional food using the food composition. The food composition for relieving hangover and improving the liver function of the present invention comprises: 30 to 40 wt% of Japanese apricot concentrate; 15 wt% of cabbage powder; 15 wt% of tomato powder; 5 wt% of chestnut powder; 3 wt% of kudzu root extract powder; 5 wt% of kelp powder; and 17 to 27 wt% of dextrin. The health functional food of the present invention comprises the food composition for relieving hangover and improving the liver function and is made into any one of granules, pills, tablets, capsules, or beverage forms.

Description

Food composition for relieving hangover and improving liver function, and health functional food using the same {Food composition for relieving hangovers and improving a liver and food containing the same}

The present invention contains plum concentrate, cabbage powder, tomato powder, chestnut powder, arrowroot extract powder, kelp powder, dextrin, and the like, thereby relieving hangover symptoms caused by drinking and effectively improving liver function lowered by alcoholic damage. It relates to a food composition for relieving a hangover and improving liver function, and a health functional food using the same.

In general, it is known that excessive alcohol intake causes a hangover and lowers liver function. The liver is the second largest organ in our body, and its representative function is to detoxify and play a major role in metabolism.

When alcohol is ingested due to drinking, the alcohol that moves through the blood vessels to the liver is converted to acetaldehyde by alcohol dehydrogenase (ADH), which is then converted to acetaldehyde dehydrogenase (ALDH). After being converted to acetate by means of which is finally decomposed into carbon dioxide and water.

The hangover caused by excessive drinking is caused by the accumulation of alcohol as ethanol and acetaldehyde in the body instead of being decomposed into carbon dioxide and water, so vomiting, diarrhea, dizziness, thirst, general malaise, fatigue, memory loss, abdominal It is a phenomenon that causes bloating, indigestion, and vitamin deficiency.

There are two types of acetaldehyde dehydrogenase: type II, which works when acetaldehyde is at a low concentration, and type I, which works when acetaldehyde is at a high concentration. Compared to Westerners, Asians lack or lack type II acetaldehyde dehydrogenase, so the decomposition of acetaldehyde is slow. Therefore, various hangover phenomena are felt more by acetaldehyde accumulated in the body without being decomposed.

In addition, alcoholic liver disease includes fatty liver due to accumulation of triglyceride in liver cells, alcoholic hepatitis causing inflammatory damage caused by alcohol, and fibrosis of liver tissue due to chronic inflammation of the liver Tissue-transformed liver cirrhosis and the like.

Therefore, until now, research on products for relieving hangover caused by excessive drinking has been conducted in various ways, and as a result, various health supplements have been developed. So far, the ingredients that have been individually recognized for their efficacy as 'helping liver health' by the Korean Ministry of Food and Drug Safety include milk thistle extract, broccoli prout powder, shiitake mushroom mycelium, shiitake mushroom mycelium extract, and bokbunja extract powder. Raw materials that have individually been recognized for their efficacy as 'help protect the liver' include extracts from H.

Recently, foods in the form of various formulations using the raw materials of the above examples have been developed, most of which are drinks, and sometimes pills are being marketed. In addition, these products are judged to have only some physiological improvement effects or to have insignificant clinical effects in scientifically proving the effects of improving liver function and relieving hangovers.

Accordingly, there is a growing need for the development of a food composition with improved functionality to help relieve hangover symptoms caused by drinking and improve liver function from alcoholic damage.

The present invention is to solve the conventional problems as described above, the purpose of which is to increase the effect of relieving hangover symptoms due to excessive drinking, and to effectively improve the alcoholic liver function deterioration food composition for hangover relief and liver function improvement And to provide a health functional food using the same.

In order to achieve the above object, the present invention is a plum concentrate 30-40% by weight, cabbage powder 15% by weight, tomato powder 15% by weight, chestnut powder 5% by weight, arrowroot extract powder 3% by weight, kelp powder 5% by weight And it is characterized in a food composition for relieving hangover and improving liver function containing 17 to 27% by weight of dextrin.

In addition, in the present invention, preferably, 40% by weight of plum concentrate and 17% by weight of dextrin are characterized in a food composition for relieving hangover and improving liver function.

In addition, the present invention is characterized by a health functional food comprising the food composition.

In addition, in the present invention, the health functional food is characterized in the health functional food consisting of any one of granules, pills, tablets, capsules or beverages.

The food composition and health functional food of the present invention having the above characteristic composition contains plum concentrate, cabbage powder, tomato powder, chestnut powder, arrowroot extract powder, kelp powder, dextrin, etc. By effectively decomposing acetaldehyde, it is possible to significantly lower the alcohol concentration and relieve stomach protection and heartburn, thereby relieving the hangover phenomenon caused by excessive drinking and enhancing the effect of improving the deteriorated liver function.

1 is a graph showing the clinical trial results for the hangover relieving efficacy of the present invention.
Figure 2 is a graph showing the AST level in a clinical trial for the liver function improvement efficacy of the present invention.
Figure 3 is a graph showing the ALT level in a clinical trial for the liver function improvement efficacy of the present invention.
Figure 4 is a graph showing the γ-GTP level in a clinical trial for the liver function improvement efficacy of the present invention.

Hereinafter, a food composition for relieving a hangover and improving liver function according to the present invention and a preferred embodiment of a health functional food using the same will be described.

The food composition for relieving hangover and improving liver function of the present invention includes plum concentrate, cabbage powder, tomato powder, chestnut powder, arrowroot extract powder, kelp powder and dextrin.

Plum concentrate is to decompose the ethanol and acetaldehyde accumulated in the body due to alcohol intake. Remove the seeds from the dried plums, grind it with a mixer, filter it through a filter cloth to extract the juice, and heat it to 5 It can be obtained by evaporating water by boiling for ~6 hours, and it is known to be effective in indigestion, food poisoning, habitual constipation, gastritis, enteritis, and recovery from fatigue.

Cabbage powder is to protect the stomach when ingesting alcohol, and can be obtained by shredding cabbage, drying it to remove moisture, and then pulverizing it. Cabbage powder is a natural anti-ulcer food with ingredients that protect and strengthen the gastric mucosa, and is known to be effective in preventing cancers such as stomach and colon cancer. It is also effective in preventing skin aging.

Tomato powder is to help the decomposition of ethanol and acetaldehyde accumulated in the body due to alcohol intake, and can be obtained by slicing tomatoes, drying them, removing moisture, and then pulverizing them. Tomatoes contain a lot of lycopene, which has excellent antioxidant effects, anti-aging and soothing effects on skin problems. Also, lycopene and vitamin C release toxic substances such as acetaldehyde accumulated in the body due to alcohol intake, so it is also effective in relieving a hangover. known to be good

Chestnut powder, for relieving heartburn, can be obtained by drying chestnut grains to remove moisture, and then pulverizing them. Chestnuts are rich in essential fatty acids, such as linoleic acid, which contain five major nutrients, such as carbohydrates, fats, proteins, vitamins, and minerals.

In addition, it has effects such as strengthening immunity, recovering from fatigue, relieving hangover, preventing osteoporosis, and improving brain function.

Arrowroot extract powder is to help the decomposition of ethanol and acetaldehyde accumulated in the body due to alcohol intake, and can be obtained by naturally drying arrowroot roots and pulverizing them. Arrowroot extract powder is good for skin such as acne and atopic dermatitis, has a nourishing and tonic effect, so it is good for fatigue recovery, and it strengthens the stomach and has good effects on indigestion, constipation, and diarrhea. In addition, it is good for excreting heavy metals accumulated in the body and preventing osteoporosis. In particular, alcohol-decomposing enzymes protect the liver and have excellent effects in relieving hangovers.

Kelp powder is for stomach protection, and can be obtained by roasting cleanly trimmed kelp at a low temperature, drying it naturally and pulverizing it. Alginic acid, laminin, and potassium in kelp powder have the effect of lowering cholesterol and blood pressure, alginic acid is effective in preventing colon cancer by excreting carcinogens in the intestine. , vitamins, iodine, iron and calcium are effective in preventing hair loss.

Dextrin is a low-molecular-weight carbohydrate obtained by hydrolyzing starch (starch), and has effects such as promoting beneficial bacteria, relieving constipation, maintaining normal blood sugar, suppressing cholesterol and weight loss, improving heart health, and improving colon health. .

The food composition for relieving hangover and improving liver function of the present invention is 30-40% by weight of plum concentrate, 15% by weight of cabbage powder, 15% by weight of tomato powder, 5% by weight of chestnut powder, 3% by weight of arrowroot extract powder, kelp powder By containing 5% by weight and 17 to 27% by weight of dextrin, it is possible to improve the effect of relieving hangover and improving liver function.

Preferably, among the above ingredients, when the plum concentrate is contained in a maximum amount of 40% by weight and dextrin is contained in a minimum amount of 17% by weight, the alcohol concentration suppression effect after drinking can be improved the most.

In addition, the present invention can be prepared as a health functional food consisting of any one of granules, pills, tablets, capsules or beverages by including the food composition.

Hereinafter, the present invention will be described in detail by means of an Example group and a control group. The following example group and control group only exemplify the present invention, and the content of the present invention is not limited by the following example group and control group.

NO Raw material name Example 1 Example 2 Example 3 control note One Plum Concentrate (50Brix) 30 35 40 0 Decomposition of acetaldehyde 2 Cabbage Powder 15 15 15 15 stomach protection 3 tomato powder 15 15 15 15 Decomposition of acetaldehyde 4 chestnut powder 5 5 5 5 relieve heartburn 5 Arrowroot Root Extract Powder 3 3 3 3 Decomposition of acetaldehyde 6 kelp powder 5 5 5 5 stomach protection 7 dextrin 27 22 17 57 carbohydrate Sum 100 100 100 100

<Example 1>

A food composition was prepared by mixing 30% by weight of plum concentrate, 15% by weight of cabbage powder, 15% by weight of tomato powder, 5% by weight of chestnut powder, 3% by weight of arrowroot extract powder, 5% by weight of kelp powder and 27% by weight of dextrin. Then, the health functional food of Example 1 was manufactured by molding into an annular shape using this food composition.

<Example 2>

A food composition was prepared by mixing 35% by weight of plum concentrate, 15% by weight of cabbage powder, 15% by weight of tomato powder, 5% by weight of chestnut powder, 3% by weight of arrowroot extract powder, 5% by weight of kelp powder, and 22% by weight of dextrin. Then, the health functional food of Example 2 was manufactured by molding into an annular shape using this food composition.

<Example 3>

A food composition was prepared by mixing 40% by weight of plum concentrate, 15% by weight of cabbage powder, 15% by weight of tomato powder, 5% by weight of chestnut powder, 3% by weight of arrowroot extract powder, 5% by weight of kelp powder and 17% by weight of dextrin. Then, the health functional food of Example 3 was prepared by molding into an annular shape using this food composition.

<control group>

A food composition was prepared by mixing 0% by weight of plum concentrate, 15% by weight of cabbage powder, 15% by weight of tomato powder, 5% by weight of chestnut powder, 3% by weight of arrowroot extract powder, 5% by weight of kelp powder and 57% by weight of dextrin. Then, a health functional food of the control group was prepared by molding into an annular shape using this food composition.

Experimental Example 1. Evaluation of the inhibition of increase in alcohol concentration in the body

The age of 30-40 years old, weight 65-75kg, 10 male subjects were used as test subjects, and alcohol intake was 400ml (alcohol content 19.5%).

In the experiment, after measuring the initial alcohol concentration 30 minutes after drinking, 5 g of health functional food prepared in each example and control was ingested, and alcohol concentration (mg/L) was measured with a breathalyzer (TNT TECH) 90 minutes after drinking. did. The experiment was conducted at an interval of 2 weeks for each example and control group.

During the duration of the experiment, the subjects were prohibited from consuming alcohol to increase the accuracy of the experiment.

1-1. Alcohol concentration measurement result
division Example 1 Example 2 30 minutes after drinking
Alcohol Concentration (mg/L) 90 minutes after drinking
Alcohol Concentration (mg/L) 30 minutes after drinking
Alcohol Concentration (mg/L) 90 minutes after drinking
Alcohol Concentration (mg/L) One 0.08 0.07 0.11 0.08 2 0.07 0.06 0.10 0.08 3 0.11 0.09 0.12 0.10 4 0.09 0.08 0.08 0.07 5 0.07 0.09 0.09 0.07 6 0.13 0.12 0.13 0.11 7 0.12 0.10 0.10 0.09 8 0.08 0.07 0.12 0.10 9 0.09 0.08 0.07 0.08 10 0.07 0.09 0.09 0.08

1-2. Alcohol concentration measurement result
division Example 3 control 30 minutes after drinking
Alcohol Concentration (mg/L) 90 minutes after drinking
Alcohol Concentration (mg/L) 30 minutes after drinking
Alcohol Concentration (mg/L) 90 minutes after drinking
Alcohol Concentration (mg/L) One 0.08 0.06 0.09 0.14 2 0.10 0.04 0.07 0.12 3 0.08 0.05 0.10 0.16 4 0.10 0.05 0.08 0.14 5 0.09 0.07 0.09 0.13 6 0.08 0.05 0.08 0.16 7 0.12 0.04 0.11 0.18 8 0.10 0.06 0.07 0.14 9 0.11 0.04 0.12 0.18 10 0.06 0.04 0.09 0.17

2. Alcohol concentration difference after 30 minutes and 90 minutes after drinking division control Example 1 Example 2 Example 3 One 0.05 -0.01 -0.03 -0.02 2 0.05 -0.01 -0.02 -0.06 3 0.06 -0.02 -0.02 -0.03 4 0.06 -0.01 -0.01 -0.05 5 0.04 0.02 -0.02 -0.02 6 0.08 -0.01 -0.02 -0.03 7 0.07 -0.02 -0.01 -0.08 8 0.07 -0.01 -0.02 -0.04 9 0.06 -0.01 0.01 -0.07 10 0.08 0.02 -0.01 -0.02

Tables 2 and 3 above show the results of the breathalyzer measurement of each Example and the control group according to Experimental Example 1. As shown in Table 4 and the alcohol concentration difference by the results of the breathalyzer test shown in Figure 1, it can be seen that the alcohol concentration is significantly lower in the case of each Example than in the control group.

Specifically, in the control group, the alcohol concentration after 90 minutes of drinking increased by about 171% compared to the alcohol concentration after 30 minutes of drinking, whereas Examples 1, 2, and 3 decreased to 95%, 86%, and 56%, respectively. .

Through the above results, it was confirmed that there is an excellent effect of reducing the alcohol concentration in the body when ingesting the food composition for relieving hangover and improving liver function of the present invention and a health functional food using the same. The effect was found to be excellent.

Experimental Example 2. Evaluation of liver function improvement

The health functional food prepared in Example 3 was administered to 5 subjects in their 30s, 5 people in their 40s, and 5 people in their 50s with decreased liver function, 5 g each morning/evening twice a day for 30 days.

The indicators of liver function improvement were compared before and after ingestion by measuring AST (aspartate aminotransferase), ALT (alanine aminotransferase), and γ-GTP (γ-guanosine triphosphate).

age division before intake after ingestion AST ALT γ-GTP AST ALT γ-GTP 30's One 118 93 88 34 29 32 2 113 87 76 25 28 26 3 97 72 69 32 35 31 4 103 81 83 24 24 22 5 89 75 71 31 27 29 40's One 115 91 86 29 32 30 2 107 82 76 34 29 28 3 124 90 84 27 24 22 4 114 92 82 29 36 31 5 120 88 75 23 31 27 50's One 119 82 79 35 24 22 2 128 91 87 30 29 28 3 136 89 83 36 37 34 4 127 93 86 29 29 26 5 121 85 83 34 24 30 Normal range (U/L) 5-40 10-40 0-60 5-40 10-40 0-60

In the case of AST (aspartate aminotransferase) levels, as shown in Table 5 and FIG. 2 above, before ingestion, all subjects were about 2-3 times higher than the maximum value in the normal range of 5-40 (U/L), but after ingestion was measured as a value within the normal range for all subjects.

Even in the case of ALT (alanine aminotransferase) levels, as shown in Table 5 and FIG. 3, before ingestion, all subjects were about 2-3 times higher than the maximum value in the normal range of 10-40 (U/L), but after ingestion, All subjects were measured to have values within the normal range.

γ-GTP (γ-guanosine triphosphate) levels, as shown in Table 5 and Figure 4, before ingestion, all subjects were about 1.5 to 2 times higher than the maximum value of the normal range 0-60 (U/L), but after ingestion was measured as a value within the normal range for all subjects.

Through the above results, it was found that when the food composition for relieving hangover and improving liver function of the present invention and a health functional food using the same are consumed, the decreased liver function can be significantly improved.

Although the embodiments of the present invention have been described by way of limited examples and drawings, various modifications and variations are possible from the above description by those skilled in the art. For example, even if the described techniques are performed in an order different from the described method, and/or the described components are combined or combined in a different form from the described method, or are substituted or substituted by other components or equivalents Appropriate results can be achieved.

Therefore, other implementations, other embodiments, and equivalents to the claims are also within the scope of the following claims.

Claims (4)

40% by weight of plum concentrate, 15% by weight of cabbage powder, 15% by weight of tomato powder, 5% by weight of chestnut powder, 3% by weight of arrowroot extract powder, 5% by weight of kelp powder, and 17% by weight of dextrin hangover A food composition for relieving and improving liver function. delete A health functional food comprising the food composition according to claim 1 . [4] The health functional food according to claim 3, wherein the health functional food is in the form of any one of granules, pills, tablets, capsules, and beverages.

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