KR102351422B1 - 철 트리말톨의 복용량 양생법 - Google Patents

철 트리말톨의 복용량 양생법 Download PDF

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Publication number
KR102351422B1
KR102351422B1 KR1020167021033A KR20167021033A KR102351422B1 KR 102351422 B1 KR102351422 B1 KR 102351422B1 KR 1020167021033 A KR1020167021033 A KR 1020167021033A KR 20167021033 A KR20167021033 A KR 20167021033A KR 102351422 B1 KR102351422 B1 KR 102351422B1
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South Korea
Prior art keywords
iron
trimatol
anemia
administered
formulation
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KR1020167021033A
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English (en)
Korean (ko)
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KR20160105499A (ko
Inventor
크리스티안 슈바이거
칼 앤드류 스테리트
줄리안 데이비드 하웰
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실드 티엑스 (유케이) 리미티드
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Priority claimed from GB201400171A external-priority patent/GB201400171D0/en
Priority claimed from GB201418708A external-priority patent/GB201418708D0/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Obesity (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020167021033A 2014-01-06 2015-01-06 철 트리말톨의 복용량 양생법 Active KR102351422B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB201400171A GB201400171D0 (en) 2014-01-06 2014-01-06 Dosage regimen
GB1400171.3 2014-01-06
GB1418708.2 2014-10-21
GB201418708A GB201418708D0 (en) 2014-10-21 2014-10-21 Dosage regimen
PCT/IB2015/050098 WO2015101971A1 (en) 2014-01-06 2015-01-06 Dosage regimen of ferric trimaltol

Publications (2)

Publication Number Publication Date
KR20160105499A KR20160105499A (ko) 2016-09-06
KR102351422B1 true KR102351422B1 (ko) 2022-01-13

Family

ID=52432872

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020167021033A Active KR102351422B1 (ko) 2014-01-06 2015-01-06 철 트리말톨의 복용량 양생법

Country Status (12)

Country Link
US (1) US10179120B2 (https=)
EP (1) EP3091974B1 (https=)
JP (2) JP6556753B2 (https=)
KR (1) KR102351422B1 (https=)
CN (2) CN106413706A (https=)
AU (1) AU2015204192B2 (https=)
BR (1) BR112016015766A2 (https=)
CA (1) CA2934836C (https=)
ES (1) ES2785391T3 (https=)
IL (1) IL246613B (https=)
SI (1) SI3091974T1 (https=)
WO (1) WO2015101971A1 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10179120B2 (en) 2014-01-06 2019-01-15 Iron Therapeutics Holdings Ag Dosage regimen of ferric trimaltol
GB201418710D0 (en) * 2014-10-21 2014-12-03 Iron Therapeutics Holdings Ag Dosage regimen
WO2017167963A1 (en) 2016-03-31 2017-10-05 Medical Research Council Methods for producing ferric maltol compositions from ligand modified and ligand coated ferric hydroxides
WO2017167970A1 (en) 2016-03-31 2017-10-05 Medical Research Council Methods for producing ferric maltol compositions from ferrous hydroxides
AU2017242905B2 (en) 2016-03-31 2020-10-22 Shield TX (UK) Limited Methods for producing ferric maltol compositions from elemental iron
CA3019478C (en) 2016-03-31 2024-02-13 United Kingdom Research And Innovation Ferric maltol compositions for use in the treatment or prevention of cancer and tumours
GB2553099A (en) * 2016-08-19 2018-02-28 Shield Tx Uk Ltd Use
IT202100018578A1 (it) * 2021-07-14 2023-01-14 Indena Spa Dispersione amorfa di maltolo ferrico e relativo processo di preparazione
CA3280511A1 (en) 2024-07-18 2026-03-01 Malian Biologicals Gmbh Iron supplementation in affective disorders and/or post-traumatic stress disorder (ptsd) and/or serotonin-dependent diseases and iron supplementation in neurodevelopmental or psychiatric disorder
GB202414014D0 (en) 2024-09-24 2024-11-06 Shield Tx Uk Ltd Use of ferric trimaltol in treating of preventing iron deficiency

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1150213B (it) * 1982-03-02 1986-12-10 Italfarmaco Spa Derivati di ferro biodisponibile esenti da gastrolesivita',procentimento di preparazione e relative composizioni farmaceutiche
SU1676626A1 (ru) * 1989-05-17 1991-09-15 Тюменский государственный медицинский институт Способ лечени железодефицитных анемий
RO113611B1 (ro) * 1990-08-03 1998-09-30 Asta Pharma Ag Preparate solide de ifosfamida, administrate oral si procedeu de obtinere
AU6010696A (en) 1995-06-10 1997-01-09 Vitra Pharmaceuticals Ltd Iron compounds, compositions, methods of making the same and uses thereof
ID18663A (id) * 1996-04-12 1998-04-30 Novartis Ag Komposisi farmasi berlapis enterik
NZ328751A (en) * 1997-09-16 1999-01-28 Bernard Charles Sherman Solid medicament containing an anionic surfactant and cyclosporin
US7135196B2 (en) 2000-09-19 2006-11-14 Vitra Pharmaceuticals Limited Iron compositions
US20050118291A1 (en) * 2003-09-10 2005-06-02 Mian-Ying Wang Formulations and methods for treating breast cancer with Morinda citrifolia and methylsulfonymethane
EP1877094A1 (en) * 2005-05-03 2008-01-16 Innozen, Inc. Edible film for transmucosal delivery of nutritional supplements
EP1757299A1 (de) * 2005-08-25 2007-02-28 Vifor (International) Ag Eisen(III)-Komplexverbindungen zur Behandlung von Eisenmangel-Zuständen bei Patienten mit chronisch-entzündlicher Darmerkrankung
US20070111936A1 (en) * 2005-11-15 2007-05-17 Vladimir Pak Complex of alpha-fetoprotein and inducers of apoptosis for the treatment of cancer
GB0808835D0 (en) * 2008-05-15 2008-06-18 Vitra Pharmaceuticals Ltd Therapeutic compositions
GB201101370D0 (en) 2011-01-27 2011-03-09 Iron Therapeutics Holdings Ag Process
JP5856725B2 (ja) * 2011-08-02 2016-02-10 和夫 酒井 うつ病治療用または予防用医薬組成物
US10179120B2 (en) 2014-01-06 2019-01-15 Iron Therapeutics Holdings Ag Dosage regimen of ferric trimaltol
GB201418710D0 (en) 2014-10-21 2014-12-03 Iron Therapeutics Holdings Ag Dosage regimen

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Harvey R.S.J., et al., Ferric trimaltol corrects iron deficiency anaemia in patients intolerant of iron, Aliment Pharmacol Ther, 1998, 12, 845-848. (1998.09.30.)*

Also Published As

Publication number Publication date
JP2019131592A (ja) 2019-08-08
IL246613B (en) 2020-05-31
CN114010629A (zh) 2022-02-08
US10179120B2 (en) 2019-01-15
JP2017501235A (ja) 2017-01-12
IL246613A0 (en) 2016-08-31
WO2015101971A1 (en) 2015-07-09
CA2934836A1 (en) 2015-07-09
AU2015204192A1 (en) 2016-07-07
CA2934836C (en) 2022-03-22
SI3091974T1 (sl) 2020-08-31
JP6556753B2 (ja) 2019-08-07
ES2785391T3 (es) 2020-10-06
US20160324822A1 (en) 2016-11-10
EP3091974A1 (en) 2016-11-16
KR20160105499A (ko) 2016-09-06
BR112016015766A2 (pt) 2017-08-08
AU2015204192B2 (en) 2020-03-26
CN106413706A (zh) 2017-02-15
EP3091974B1 (en) 2020-04-01

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