KR102314451B1 - 단백질 키나아제 a의 촉매 서브 유닛 알파에 특이적으로 결합하는 단일클론항체 및 이를 활용한 암 진단 용도 - Google Patents

단백질 키나아제 a의 촉매 서브 유닛 알파에 특이적으로 결합하는 단일클론항체 및 이를 활용한 암 진단 용도 Download PDF

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KR102314451B1
KR102314451B1 KR1020210003891A KR20210003891A KR102314451B1 KR 102314451 B1 KR102314451 B1 KR 102314451B1 KR 1020210003891 A KR1020210003891 A KR 1020210003891A KR 20210003891 A KR20210003891 A KR 20210003891A KR 102314451 B1 KR102314451 B1 KR 102314451B1
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Prior art keywords
antibody
cancer
group
seq
pka
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KR1020210003891A
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English (en)
Korean (ko)
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정의석
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크레너지 주식회사
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Priority to KR1020210003891A priority Critical patent/KR102314451B1/ko
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Publication of KR102314451B1 publication Critical patent/KR102314451B1/ko
Priority to PCT/KR2021/019380 priority patent/WO2022154288A1/fr

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Hospice & Palliative Care (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
KR1020210003891A 2021-01-12 2021-01-12 단백질 키나아제 a의 촉매 서브 유닛 알파에 특이적으로 결합하는 단일클론항체 및 이를 활용한 암 진단 용도 KR102314451B1 (ko)

Priority Applications (2)

Application Number Priority Date Filing Date Title
KR1020210003891A KR102314451B1 (ko) 2021-01-12 2021-01-12 단백질 키나아제 a의 촉매 서브 유닛 알파에 특이적으로 결합하는 단일클론항체 및 이를 활용한 암 진단 용도
PCT/KR2021/019380 WO2022154288A1 (fr) 2021-01-12 2021-12-20 Anticorps monoclonal se liant de manière spécifique à la protéine kinase a d'une sous-unité catalytique alpha, et son utilisation pour le diagnostic du cancer

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1020210003891A KR102314451B1 (ko) 2021-01-12 2021-01-12 단백질 키나아제 a의 촉매 서브 유닛 알파에 특이적으로 결합하는 단일클론항체 및 이를 활용한 암 진단 용도

Publications (1)

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KR102314451B1 true KR102314451B1 (ko) 2021-10-20

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KR1020210003891A KR102314451B1 (ko) 2021-01-12 2021-01-12 단백질 키나아제 a의 촉매 서브 유닛 알파에 특이적으로 결합하는 단일클론항체 및 이를 활용한 암 진단 용도

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KR (1) KR102314451B1 (fr)
WO (1) WO2022154288A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022154288A1 (fr) * 2021-01-12 2022-07-21 주식회사 낙스 Anticorps monoclonal se liant de manière spécifique à la protéine kinase a d'une sous-unité catalytique alpha, et son utilisation pour le diagnostic du cancer

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20030036011A (ko) * 2001-10-30 2003-05-09 주식회사 에이.비.아이 암 진단을 위한 항프로테인 키나제 에이 항체를 이용한효소면역측정법
KR20050054387A (ko) * 2003-12-04 2005-06-10 주식회사 에이.비.아이 암진단용 프로테인 키나제 에이 항체 분절 및 알칼리성포스파타제의 융합단백질

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8455200B2 (en) * 2009-10-15 2013-06-04 Traxxsson, Llc Measurement of PKA for cancer detection
KR102314451B1 (ko) * 2021-01-12 2021-10-20 크레너지 주식회사 단백질 키나아제 a의 촉매 서브 유닛 알파에 특이적으로 결합하는 단일클론항체 및 이를 활용한 암 진단 용도

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20030036011A (ko) * 2001-10-30 2003-05-09 주식회사 에이.비.아이 암 진단을 위한 항프로테인 키나제 에이 항체를 이용한효소면역측정법
KR20050054387A (ko) * 2003-12-04 2005-06-10 주식회사 에이.비.아이 암진단용 프로테인 키나제 에이 항체 분절 및 알칼리성포스파타제의 융합단백질

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Ou J. et al, PLOS ONE p.1-20 & S4 Table (2020.11. 6.)* *
SMITH F.D. et al, Biochem J. 438(1): 103~110. (2011. 8.15)* *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022154288A1 (fr) * 2021-01-12 2022-07-21 주식회사 낙스 Anticorps monoclonal se liant de manière spécifique à la protéine kinase a d'une sous-unité catalytique alpha, et son utilisation pour le diagnostic du cancer

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