KR102312817B1 - C1-에스테라제 억제제를 사용한 장기 이식 환자에서의 항체-매개성 거부반응의 치료 방법 - Google Patents

C1-에스테라제 억제제를 사용한 장기 이식 환자에서의 항체-매개성 거부반응의 치료 방법 Download PDF

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KR102312817B1
KR102312817B1 KR1020167013463A KR20167013463A KR102312817B1 KR 102312817 B1 KR102312817 B1 KR 102312817B1 KR 1020167013463 A KR1020167013463 A KR 1020167013463A KR 20167013463 A KR20167013463 A KR 20167013463A KR 102312817 B1 KR102312817 B1 KR 102312817B1
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콜린 브룸
마르크 이. 욱니스
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다케다 야쿠힌 고교 가부시키가이샤
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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020167013463A 2013-11-22 2014-11-21 C1-에스테라제 억제제를 사용한 장기 이식 환자에서의 항체-매개성 거부반응의 치료 방법 Active KR102312817B1 (ko)

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Application Number Priority Date Filing Date Title
KR1020217032180A KR102384814B1 (ko) 2013-11-22 2014-11-21 C1-에스테라제 억제제를 사용한 장기 이식 환자에서의 항체-매개성 거부반응의 치료 방법

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361907550P 2013-11-22 2013-11-22
US61/907,550 2013-11-22
US201462029086P 2014-07-25 2014-07-25
US62/029,086 2014-07-25
PCT/US2014/066784 WO2015077543A1 (en) 2013-11-22 2014-11-21 Methods of treating antibody-mediated rejection in organ transplant patients with c1-esterase inhibitor

Related Child Applications (1)

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KR1020217032180A Division KR102384814B1 (ko) 2013-11-22 2014-11-21 C1-에스테라제 억제제를 사용한 장기 이식 환자에서의 항체-매개성 거부반응의 치료 방법

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KR20160079821A KR20160079821A (ko) 2016-07-06
KR102312817B1 true KR102312817B1 (ko) 2021-10-13

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KR1020167013463A Active KR102312817B1 (ko) 2013-11-22 2014-11-21 C1-에스테라제 억제제를 사용한 장기 이식 환자에서의 항체-매개성 거부반응의 치료 방법
KR1020217032180A Active KR102384814B1 (ko) 2013-11-22 2014-11-21 C1-에스테라제 억제제를 사용한 장기 이식 환자에서의 항체-매개성 거부반응의 치료 방법

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US (3) US9895428B2 (https=)
EP (3) EP4162947A1 (https=)
JP (5) JP6431912B2 (https=)
KR (2) KR102312817B1 (https=)
CN (2) CN111388655A (https=)
AU (2) AU2014352846B2 (https=)
BR (1) BR112016011499A2 (https=)
CA (1) CA2930964A1 (https=)
CY (1) CY1121298T1 (https=)
DK (1) DK3071219T3 (https=)
ES (1) ES2708655T3 (https=)
HR (1) HRP20190184T1 (https=)
HU (1) HUE041809T2 (https=)
LT (1) LT3071219T (https=)
ME (1) ME03318B (https=)
MX (2) MX378834B (https=)
NZ (2) NZ719724A (https=)
PL (1) PL3071219T3 (https=)
PT (1) PT3071219T (https=)
RS (1) RS58343B1 (https=)
SG (1) SG10201804326SA (https=)
SI (1) SI3071219T1 (https=)
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Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ719724A (en) * 2013-11-22 2022-08-26 Takeda Pharmaceuticals Co Methods of treating antibody-mediated rejection in organ transplant patients with c1-esterase inhibitor
CA3075686A1 (en) * 2017-09-15 2019-03-21 Cedars-Sinai Medical Center Methods for improving organ function in organ transplant patients
WO2019166572A1 (en) * 2018-02-28 2019-09-06 Pharming Intellectual Property B.V. Pharmaceutical system for transdermal administration of a c1 -esterase inhibitor
US20220073605A1 (en) * 2018-12-20 2022-03-10 Cedars-Sinai Medical Center Clazakizumab in the treatment of chronic antibody-mediated rejection of organ transplant
AU2020327043A1 (en) * 2019-08-08 2022-02-24 Cedars-Sinai Medical Center Methods of improving organ function
EP3895726A1 (en) 2020-04-17 2021-10-20 Pharming Intellectual Property BV Using c1 esterase inhibitor to treat viral infection-related acute respiratory distress
AU2021381360A1 (en) * 2020-11-20 2023-06-22 Csl Behring Gmbh Method for treating antibody-mediated rejection
CN113035369B (zh) * 2021-03-10 2021-12-03 浙江大学 一种肾移植抗感染药物剂量预测模型的构建方法
JP2024525084A (ja) 2021-07-09 2024-07-09 ファーミング・インテレクチュアル・プロパティー・ビー．ブイ． Ｃ１エステラーゼ阻害剤によるウイルス感染関連症状の治療
WO2024152030A1 (en) * 2023-01-13 2024-07-18 The Uab Research Foundation Crossmatching for porcine xenotransplantation

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JP4212278B2 (ja) * 2001-03-01 2009-01-21 日本たばこ産業株式会社 移植片拒絶反応抑制剤
DE10112617A1 (de) 2001-03-14 2002-10-02 Aventis Behring Gmbh Verwendung eines C1-Esterase-Inhibitors zur Verhinderung oder Verzögerung der Abstoßung von Xenotransplantaten in Säugetieren
US20090118162A1 (en) 2005-06-07 2009-05-07 Regents Of The University Of Colorado Inhibitors of serine protease activity and their use in methods and compositions for treatment of graft rejection and promotion of graft survival
RS53864B1 (sr) * 2006-03-02 2015-08-31 Alexion Pharmaceuticals, Inc. Produžavanje preživljavanja alografta inhibiranjem aktivnosti komplementa
DK2758076T3 (en) * 2011-09-24 2019-04-01 Csl Behring Gmbh COMBINATION THERAPY USING IMMUNOGLOBULIN AND C1 INHIBITOR
CA2901225C (en) * 2013-03-08 2023-09-19 Csl Behring Gmbh Treatment and prevention of remote ischemia-reperfusion injury
BR112015023207A8 (pt) * 2013-03-15 2018-01-23 Shire Viropharma Inc composições de ci-inh e métodos para prevenção e tratamento de desordens associadas à deficiência de inibidor de c1 esterase.
NZ719724A (en) * 2013-11-22 2022-08-26 Takeda Pharmaceuticals Co Methods of treating antibody-mediated rejection in organ transplant patients with c1-esterase inhibitor

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ClinicalTrials.gov Archive (2013.11.18.), URL:https://ciinicaltrials.gov/archive/NCT01147302/2013_11_18*
J Immunol, Vol. 190, pp. 3839-3847 (2013.04.15.)*

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EP3071219B1 (en) 2018-11-14
CA2930964A1 (en) 2015-05-28
JP6620206B2 (ja) 2019-12-11
BR112016011499A2 (pt) 2020-10-27
AU2014352846A1 (en) 2016-06-02
SI3071219T1 (sl) 2019-03-29
JP2022179637A (ja) 2022-12-02
RS58343B1 (sr) 2019-03-29
MX2016006656A (es) 2016-09-06
JP2016537380A (ja) 2016-12-01
HUE041809T2 (hu) 2019-05-28
KR20160079821A (ko) 2016-07-06
JP2019023233A (ja) 2019-02-14
CN105744949A (zh) 2016-07-06
US20150147319A1 (en) 2015-05-28
JP2021063141A (ja) 2021-04-22
ME03318B (me) 2019-10-20
KR20210125118A (ko) 2021-10-15
CN111388655A (zh) 2020-07-10
MX378834B (es) 2025-03-11
PT3071219T (pt) 2019-02-06
HRP20190184T1 (hr) 2019-03-22
KR102384814B1 (ko) 2022-04-08
MX2021000332A (es) 2021-04-13
EP4162947A1 (en) 2023-04-12
AU2014352846B2 (en) 2019-10-03
LT3071219T (lt) 2019-01-10
WO2015077543A1 (en) 2015-05-28
JP2019001831A (ja) 2019-01-10
SG10201804326SA (en) 2018-06-28
NZ719724A (en) 2022-08-26
US20180104319A1 (en) 2018-04-19
DK3071219T3 (en) 2019-02-25
EP3494988A1 (en) 2019-06-12
CY1121298T1 (el) 2020-05-29
ES2708655T3 (es) 2019-04-10
JP6431912B2 (ja) 2018-11-28
EP3494988B1 (en) 2022-08-03
NZ759187A (en) 2022-08-26
PL3071219T3 (pl) 2019-04-30
US20200360495A1 (en) 2020-11-19
AU2020200015B2 (en) 2022-03-10
AU2020200015A1 (en) 2020-01-30
SMT201900042T1 (it) 2019-02-28
EP3071219A1 (en) 2016-09-28
US9895428B2 (en) 2018-02-20

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