KR102308673B1 - 칼륨의 감소 및 만성 신장 및/또는 만성 심장 질환의 치료를 위한 미세다공성 규산지르코늄 및 이뇨제 - Google Patents

칼륨의 감소 및 만성 신장 및/또는 만성 심장 질환의 치료를 위한 미세다공성 규산지르코늄 및 이뇨제 Download PDF

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KR102308673B1
KR102308673B1 KR1020157031787A KR20157031787A KR102308673B1 KR 102308673 B1 KR102308673 B1 KR 102308673B1 KR 1020157031787 A KR1020157031787 A KR 1020157031787A KR 20157031787 A KR20157031787 A KR 20157031787A KR 102308673 B1 KR102308673 B1 KR 102308673B1
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potassium
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crystals
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도날드 제프리 카이저
알바로 에프. 길렘
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제트에스 파마, 인코포레이티드
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    • A61K31/336Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having three-membered rings, e.g. oxirane, fumagillin
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KR1020157031787A 2013-04-05 2014-04-03 칼륨의 감소 및 만성 신장 및/또는 만성 심장 질환의 치료를 위한 미세다공성 규산지르코늄 및 이뇨제 Active KR102308673B1 (ko)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201361808897P 2013-04-05 2013-04-05
US61/808,897 2013-04-05
US201361914362P 2013-12-10 2013-12-10
US61/914,362 2013-12-10
US201461930331P 2014-01-22 2014-01-22
US61/930,331 2014-01-22
PCT/US2014/032815 WO2014165670A1 (en) 2013-04-05 2014-04-03 Microporous zirconium silicate and diuretics for the reduction of potassium and treatment of chronic kidney and/or chronic heart disease

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KR20150140750A KR20150140750A (ko) 2015-12-16
KR102308673B1 true KR102308673B1 (ko) 2021-10-01

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KR1020157031787A Active KR102308673B1 (ko) 2013-04-05 2014-04-03 칼륨의 감소 및 만성 신장 및/또는 만성 심장 질환의 치료를 위한 미세다공성 규산지르코늄 및 이뇨제

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US (3) US20140302175A1 (enExample)
EP (1) EP2981272B1 (enExample)
JP (1) JP6280636B2 (enExample)
KR (1) KR102308673B1 (enExample)
CN (1) CN105473151B (enExample)
AU (1) AU2014248081B2 (enExample)
BR (1) BR112015025438B1 (enExample)
CA (1) CA2908641C (enExample)
CL (1) CL2015002951A1 (enExample)
DK (1) DK2981272T3 (enExample)
ES (1) ES2943007T3 (enExample)
FI (1) FI2981272T3 (enExample)
HU (1) HUE061862T2 (enExample)
IL (1) IL241926B (enExample)
MX (1) MX2015014055A (enExample)
PH (1) PH12015502301A1 (enExample)
PL (1) PL2981272T3 (enExample)
PT (1) PT2981272T (enExample)
TW (1) TW201521746A (enExample)
WO (1) WO2014165670A1 (enExample)
ZA (1) ZA201507666B (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SMT201900037T1 (it) 2011-02-11 2019-02-28 Zs Pharma Inc Uso di un silicato di zirconio per il trattamento di iperkaliemia
US9592253B1 (en) 2015-10-14 2017-03-14 ZS Pharma, Inc. Extended use zirconium silicate compositions and methods of use thereof
CN114917247B (zh) * 2022-05-18 2024-01-26 广东省疾病预防控制中心 纳米二氧化钛在防治肾损伤中的应用
CN117776193A (zh) * 2023-12-25 2024-03-29 杭州国瑞生物科技有限公司 一种环硅酸锆钠zs-9的制备方法及其应用

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6159505A (en) 1996-01-24 2000-12-12 Piper; Edwina M. Compositions for the treatment of migraine, containing potassium, magnesium and pyridoxine
US20100104527A1 (en) 2008-08-22 2010-04-29 Relypsa, Inc. Treating hyperkalemia with crosslinked cation exchange polymers of improved physical properties
US20120213847A1 (en) * 2011-02-11 2012-08-23 ZS Pharma, Inc. Microporous zirconium silicate for the treatment of hyperkalemia

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US5891417A (en) 1997-04-08 1999-04-06 Uop Llc Zirconium silicate and zirconium germanate molecular sieves and process using the same
US5888472A (en) 1997-04-08 1999-03-30 Uop Llc Zirconium silicate molecular sieves and process using the same
US6099737A (en) 1999-03-29 2000-08-08 Uop Llc Process for removing toxins from blood using zirconium metallate or titanium metallate compositions
US6332985B1 (en) 1999-03-29 2001-12-25 Uop Llc Process for removing toxins from bodily fluids using zirconium or titanium microporous compositions
EP1307270A1 (en) * 2000-07-12 2003-05-07 Uop Llc Process for removing toxins from bodily fluids using zirconium or titanium microporous compositions
AU2002242103A1 (en) * 2001-02-06 2002-08-19 Ash Medical Systems, Inc. Monovalent-selective cation exchangers as oral sorbent therapy
US6579460B1 (en) * 2001-03-13 2003-06-17 Uop Llc Process and composition for removing toxins from bodily fluids
CN103919792B (zh) 2008-08-22 2018-03-09 瑞立普萨公司 交联阳离子交换聚合物、组合物及在治疗方法高钾血症中的应用
US20120070468A1 (en) * 2010-09-16 2012-03-22 Uop Llc Removal of toxins from gastrointestinal fluids
MX2015000381A (es) * 2012-07-11 2015-11-23 Zs Pharma Inc Silicato de zirconio microporoso para el tratamiento de la hipercalemia en pacientes hipercalcemicos y composiciones con calcio mejoradas para el tratamiento de la hipercalemia.
KR102184602B1 (ko) * 2012-10-22 2020-11-30 제트에스 파마, 인코포레이티드 고칼륨혈증의 치료를 위한 미세다공성 지르코늄 실리케이트

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6159505A (en) 1996-01-24 2000-12-12 Piper; Edwina M. Compositions for the treatment of migraine, containing potassium, magnesium and pyridoxine
US20100104527A1 (en) 2008-08-22 2010-04-29 Relypsa, Inc. Treating hyperkalemia with crosslinked cation exchange polymers of improved physical properties
US20120213847A1 (en) * 2011-02-11 2012-08-23 ZS Pharma, Inc. Microporous zirconium silicate for the treatment of hyperkalemia

Also Published As

Publication number Publication date
JP6280636B2 (ja) 2018-02-14
CA2908641C (en) 2022-10-18
EP2981272A1 (en) 2016-02-10
IL241926B (en) 2020-10-29
AU2014248081B2 (en) 2019-02-28
MX2015014055A (es) 2015-12-15
CL2015002951A1 (es) 2016-11-11
FI2981272T3 (fi) 2023-05-03
HUE061862T2 (hu) 2023-08-28
EP2981272A4 (en) 2016-12-07
WO2014165670A1 (en) 2014-10-09
EP2981272B1 (en) 2023-03-01
KR20150140750A (ko) 2015-12-16
US20140302175A1 (en) 2014-10-09
CN105473151B (zh) 2018-09-18
DK2981272T3 (da) 2023-05-01
US10695366B2 (en) 2020-06-30
BR112015025438B1 (pt) 2022-06-07
JP2016515624A (ja) 2016-05-30
HK1221177A1 (en) 2017-05-26
AU2014248081A1 (en) 2015-11-12
PH12015502301A1 (en) 2016-02-10
US20180271902A1 (en) 2018-09-27
ES2943007T3 (es) 2023-06-08
CN105473151A (zh) 2016-04-06
CA2908641A1 (en) 2014-10-09
PL2981272T3 (pl) 2023-05-29
ZA201507666B (en) 2019-09-25
PT2981272T (pt) 2023-05-03
BR112015025438A2 (pt) 2017-07-18
TW201521746A (zh) 2015-06-16
US20160051584A1 (en) 2016-02-25

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