KR102250214B1 - 1-인단설파미드 유도체를 포함하는 통증에 대한 치료제 및/또는 예방제 - Google Patents

1-인단설파미드 유도체를 포함하는 통증에 대한 치료제 및/또는 예방제 Download PDF

Info

Publication number
KR102250214B1
KR102250214B1 KR1020167014850A KR20167014850A KR102250214B1 KR 102250214 B1 KR102250214 B1 KR 102250214B1 KR 1020167014850 A KR1020167014850 A KR 1020167014850A KR 20167014850 A KR20167014850 A KR 20167014850A KR 102250214 B1 KR102250214 B1 KR 102250214B1
Authority
KR
South Korea
Prior art keywords
pain
mmol
dihydro
inden
room temperature
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
KR1020167014850A
Other languages
English (en)
Korean (ko)
Other versions
KR20160106053A (ko
Inventor
히로유키 히가시야마
유지 가즈타
게이스케 하시모토
Original Assignee
에자이 알앤드디 매니지먼트 가부시키가이샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 에자이 알앤드디 매니지먼트 가부시키가이샤 filed Critical 에자이 알앤드디 매니지먼트 가부시키가이샤
Publication of KR20160106053A publication Critical patent/KR20160106053A/ko
Application granted granted Critical
Publication of KR102250214B1 publication Critical patent/KR102250214B1/ko
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays or needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
KR1020167014850A 2013-12-19 2014-12-17 1-인단설파미드 유도체를 포함하는 통증에 대한 치료제 및/또는 예방제 Active KR102250214B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2013262743 2013-12-19
JPJP-P-2013-262743 2013-12-19
PCT/JP2014/083374 WO2015093515A1 (ja) 2013-12-19 2014-12-17 １－インダンスルファミド誘導体を含む疼痛の治療および／または予防剤

Publications (2)

Publication Number Publication Date
KR20160106053A KR20160106053A (ko) 2016-09-09
KR102250214B1 true KR102250214B1 (ko) 2021-05-07

Family

ID=53402860

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020167014850A Active KR102250214B1 (ko) 2013-12-19 2014-12-17 1-인단설파미드 유도체를 포함하는 통증에 대한 치료제 및/또는 예방제

Country Status (14)

Country Link
US (1) US9610262B2 (https=)
EP (1) EP3085369B1 (https=)
JP (1) JP6518595B2 (https=)
KR (1) KR102250214B1 (https=)
CN (1) CN105792821B (https=)
AU (1) AU2014367781B2 (https=)
BR (1) BR112016012833B1 (https=)
CA (1) CA2932529C (https=)
ES (1) ES2673876T3 (https=)
IL (1) IL246036B (https=)
MX (1) MX370898B (https=)
RU (1) RU2678571C1 (https=)
SG (1) SG11201604484UA (https=)
WO (1) WO2015093515A1 (https=)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20240069905A (ko) 2022-11-11 2024-05-21 덕산에테르씨티 주식회사 내화성능 및 강도가 보강된 압력용기
KR20240069904A (ko) 2022-11-11 2024-05-21 덕산에테르씨티 주식회사 내화성능 및 강도가 보강된 압력용기
KR20240069903A (ko) 2022-11-11 2024-05-21 덕산에테르씨티 주식회사 내화성능 및 강도가 보강된 압력용기
KR20250063587A (ko) 2023-11-01 2025-05-08 덕산에테르씨티 주식회사 압력 용기의 숄더부 보호용 커버
KR20250063589A (ko) 2023-11-01 2025-05-08 덕산에테르씨티 주식회사 압력 용기의 숄더부 보호용 커버
KR20250063588A (ko) 2023-11-01 2025-05-08 덕산에테르씨티 주식회사 압력 용기의 숄더부 보호용 커버

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20200132858A (ko) * 2018-03-20 2020-11-25 에자이 알앤드디 매니지먼트 가부시키가이샤 간질 치료제
TW202345782A (zh) * 2022-04-27 2023-12-01 日商衛材R&D企管股份有限公司 帕金森氏症治療用醫藥組成物

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010115952A1 (en) 2009-04-09 2010-10-14 N.V. Organon Indane derivatives
WO2012038081A1 (de) 2010-09-22 2012-03-29 Grünenthal GmbH Substituierte benzamid-verbindungen
WO2013191144A1 (ja) 2012-06-21 2013-12-27 エーザイ・アール・アンド・ディー・マネジメント株式会社 新規インダンスルファミド誘導体

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8716231B2 (en) 2005-12-19 2014-05-06 Janssen Pharmaceutica Nv Use of benzo-fused heterocycle sulfamide derivatives for the treatment of pain
US20070191452A1 (en) 2006-02-15 2007-08-16 Smith-Swintosky Virginia L Use of benzo-heteroaryl sulfamide derivatives for the treatment of pain
CL2007002994A1 (es) 2006-10-19 2008-02-08 Wyeth Corp Compuestos derivados heterociclicos que contienen sulfamoilo, inhibidores de hsp90; composicion farmaceutica; y uso para el tratamiento del cancer, tal como cancer de mama, de colon y prostata, entre otros.
TWI433674B (zh) 2006-12-28 2014-04-11 Infinity Discovery Inc 環杷明（ｃｙｃｌｏｐａｍｉｎｅ）類似物類
RU2508295C2 (ru) * 2012-03-22 2014-02-27 Общество с ограниченной ответственностью "Биофармокс" Синтетические пептиды с ненаркотическим типом анальгетического действия

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010115952A1 (en) 2009-04-09 2010-10-14 N.V. Organon Indane derivatives
WO2012038081A1 (de) 2010-09-22 2012-03-29 Grünenthal GmbH Substituierte benzamid-verbindungen
WO2013191144A1 (ja) 2012-06-21 2013-12-27 エーザイ・アール・アンド・ディー・マネジメント株式会社 新規インダンスルファミド誘導体

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20240069905A (ko) 2022-11-11 2024-05-21 덕산에테르씨티 주식회사 내화성능 및 강도가 보강된 압력용기
KR20240069904A (ko) 2022-11-11 2024-05-21 덕산에테르씨티 주식회사 내화성능 및 강도가 보강된 압력용기
KR20240069903A (ko) 2022-11-11 2024-05-21 덕산에테르씨티 주식회사 내화성능 및 강도가 보강된 압력용기
KR20250063587A (ko) 2023-11-01 2025-05-08 덕산에테르씨티 주식회사 압력 용기의 숄더부 보호용 커버
KR20250063589A (ko) 2023-11-01 2025-05-08 덕산에테르씨티 주식회사 압력 용기의 숄더부 보호용 커버
KR20250063588A (ko) 2023-11-01 2025-05-08 덕산에테르씨티 주식회사 압력 용기의 숄더부 보호용 커버

Also Published As

Publication number Publication date
IL246036B (en) 2018-11-29
AU2014367781B2 (en) 2019-07-04
JPWO2015093515A1 (ja) 2017-03-23
EP3085369B1 (en) 2018-04-04
EP3085369A1 (en) 2016-10-26
US9610262B2 (en) 2017-04-04
WO2015093515A1 (ja) 2015-06-25
SG11201604484UA (en) 2016-07-28
ES2673876T3 (es) 2018-06-26
EP3085369A4 (en) 2017-05-10
RU2016122189A (ru) 2018-01-24
RU2678571C1 (ru) 2019-01-30
CN105792821A (zh) 2016-07-20
CA2932529A1 (en) 2015-06-25
US20160303058A1 (en) 2016-10-20
JP6518595B2 (ja) 2019-05-22
IL246036A0 (en) 2016-07-31
BR112016012833B1 (pt) 2022-11-16
BR112016012833A2 (https=) 2017-08-08
AU2014367781A1 (en) 2016-06-23
CA2932529C (en) 2022-03-22
CN105792821B (zh) 2018-05-04
MX370898B (es) 2020-01-09
KR20160106053A (ko) 2016-09-09
MX2016007370A (es) 2016-10-03

Similar Documents

Publication Publication Date Title
KR102250214B1 (ko) 1-인단설파미드 유도체를 포함하는 통증에 대한 치료제 및/또는 예방제
JP7530390B2 (ja) 新規ｅｇｆｒ阻害剤
CN108395452B (zh) 作为钠通道调节剂的吡啶酮酰胺的前药
CN110088107B (zh) 化合物、组合物及其用途
AU2013278450B2 (en) Novel indanesulfamide derivative
EP1908753B1 (en) Novel heterocyclidene acetamide derivative
CN105254557A (zh) 作为钙或钠通道阻滞剂的芳基取代羧酰胺衍生物
EA018011B1 (ru) Катехоламиновые производные, полезные для лечения болезни паркинсона
WO2008011487A2 (en) L-benzyl-l-hydr0xy-2, 3-diamin0-propyl amines and 3-benzyl-3-hydroxy-2-amino-propionicacid amides for chronic pain
CA3062452A1 (en) Compositions, combinations, and methods thereof for treatment of neurological disorders
WO2010010935A1 (ja) 光学活性なヘテロシクリデン－ｎ－アリールアセトアミド誘導体
JP2021073171A (ja) （ｒ）−ジミラセタム（１）と（ｓ）−ジミラセタム（２）を非ラセミ比で含む相乗的組成物
CN1128030A (zh) 具有中枢神经系统活性的杂环胺
WO2015044229A1 (en) New pi3k/akt/mtor inhibitors and pharmaceutical uses thereof
WO2025167978A1 (en) Cyclin-dependent kinase (cdk) 12 and/or cdk13 inhibitor combinations and uses thereof
JP6885560B2 (ja) モルヒナン誘導体及びその医薬用途
US20140371165A1 (en) Identification of NSC23925 Isomers to Reverse Multidrug Resistance in Human Cancers
TWI387455B (zh) 苯并-稠合的雜環磺醯胺衍生物用於治療疼痛之用途
US20060223824A1 (en) Serotonergic agents
WO2007020631A2 (en) Tetracyclic benzofuran derivatives with therapeutic activities

Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20160603

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
A201 Request for examination
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20191021

Comment text: Request for Examination of Application

E701 Decision to grant or registration of patent right
PE0701 Decision of registration

Patent event code: PE07011S01D

Comment text: Decision to Grant Registration

Patent event date: 20210209

GRNT Written decision to grant
PR0701 Registration of establishment

Comment text: Registration of Establishment

Patent event date: 20210503

Patent event code: PR07011E01D

PR1002 Payment of registration fee

Payment date: 20210503

End annual number: 3

Start annual number: 1

PG1601 Publication of registration