KR102246699B1 - 암 검출을 위한 뉴클레오솜-전사 인자 복합체의 용도 - Google Patents

암 검출을 위한 뉴클레오솜-전사 인자 복합체의 용도 Download PDF

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KR102246699B1
KR102246699B1 KR1020187029952A KR20187029952A KR102246699B1 KR 102246699 B1 KR102246699 B1 KR 102246699B1 KR 1020187029952 A KR1020187029952 A KR 1020187029952A KR 20187029952 A KR20187029952 A KR 20187029952A KR 102246699 B1 KR102246699 B1 KR 102246699B1
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nucleosome
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KR20190013707A (ko
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제이콥 빈센트 미칼레프
조지 레이스-필류
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벨지언 볼리션 에스피알엘
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6875Nucleoproteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57488Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds identifable in body fluids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701Details
    • G01N2333/4703Regulators; Modulating activity
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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  • Proteomics, Peptides & Aminoacids (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020187029952A 2016-03-22 2017-03-22 암 검출을 위한 뉴클레오솜-전사 인자 복합체의 용도 Active KR102246699B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020217012412A KR102369544B1 (ko) 2016-03-22 2017-03-22 암 검출을 위한 뉴클레오솜-전사 인자 복합체의 용도

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1604806.8 2016-03-22
GBGB1604806.8A GB201604806D0 (en) 2016-03-22 2016-03-22 Method of identifying a cancer of unknown origin
PCT/EP2017/056851 WO2017162755A1 (en) 2016-03-22 2017-03-22 Use of nucleosome-transcription factor complexes for cancer detection

Related Child Applications (1)

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KR1020217012412A Division KR102369544B1 (ko) 2016-03-22 2017-03-22 암 검출을 위한 뉴클레오솜-전사 인자 복합체의 용도

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KR20190013707A KR20190013707A (ko) 2019-02-11
KR102246699B1 true KR102246699B1 (ko) 2021-05-04

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KR1020187029952A Active KR102246699B1 (ko) 2016-03-22 2017-03-22 암 검출을 위한 뉴클레오솜-전사 인자 복합체의 용도
KR1020217012412A Expired - Fee Related KR102369544B1 (ko) 2016-03-22 2017-03-22 암 검출을 위한 뉴클레오솜-전사 인자 복합체의 용도

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US (1) US20200363418A1 (enExample)
EP (3) EP3433616B2 (enExample)
JP (1) JP6777757B2 (enExample)
KR (2) KR102246699B1 (enExample)
CN (1) CN109313192B (enExample)
AU (1) AU2017238442A1 (enExample)
CA (1) CA3018428C (enExample)
ES (2) ES2861440T5 (enExample)
GB (1) GB201604806D0 (enExample)
MY (1) MY187655A (enExample)
SG (1) SG11201807991QA (enExample)
WO (1) WO2017162755A1 (enExample)

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TW202238131A (zh) 2020-11-25 2022-10-01 比利時商比利時意志有限公司 測量無細胞核蛋白染色質片段之方法
TW202242145A (zh) 2020-12-29 2022-11-01 比利時商比利時意志有限公司 核小體耗盡循環無細胞染色質片段之轉錄因子結合位點分析
TW202242130A (zh) 2020-12-29 2022-11-01 比利時商比利時意志有限公司 循環轉錄因子分析
WO2023048509A1 (ko) * 2021-09-24 2023-03-30 주식회사 온코크로스 종양의 원발부위 결정 방법
WO2025073909A1 (en) 2023-10-04 2025-04-10 Belgian Volition Srl Pcr method for detecting ctcf occupied cfdna fragments

Citations (1)

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US20160003848A1 (en) 2013-02-28 2016-01-07 Singapore Volition Pte Limited Method for predicting therapy efficacy using nucleosome structure biomarkers

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WO2001073133A1 (en) * 2000-03-27 2001-10-04 Thomas Jefferson University Compositions and methods for identifying and targeting cancer cells
CA2459972A1 (en) * 2001-09-14 2003-03-27 F. Hoffmann-La Roche Ag Differential diagnosis of disorders of iron metabolism by means of three independent parameters and recommendations for the treatment of these disorders of iron metabolism
US7248921B2 (en) * 2003-06-02 2007-07-24 Cameron Health, Inc. Method and devices for performing cardiac waveform appraisal
US20040018525A1 (en) * 2002-05-21 2004-01-29 Bayer Aktiengesellschaft Methods and compositions for the prediction, diagnosis, prognosis, prevention and treatment of malignant neoplasma
US20040236188A1 (en) * 2003-05-19 2004-11-25 Ge Medical Systems Information Method and apparatus for monitoring using a mathematical model
US8029989B2 (en) * 2005-08-26 2011-10-04 The Trustees Of The University Of Pennsylvania Method using snail transcriptional repressor
US20090298097A1 (en) * 2007-07-17 2009-12-03 Harris Pamela J Methods for the diagnosis of lung cancer
US20110160399A1 (en) * 2008-07-01 2011-06-30 Nihon University Histone modification inhibitor specific to target gene
MY148542A (en) * 2009-06-15 2013-04-30 Cancer Res Initiatives Foundation A method for the assessment of cancer in a biological sample obtained from a subject
EP2270510A1 (en) * 2009-07-02 2011-01-05 EMBL (European Molecular Biology Laboratory) Diagnostic method for predicting the risk of cancer recurrence based on Histone macroH2A isoforms
GB201115098D0 (en) * 2011-09-01 2011-10-19 Belgian Volition Sa Method for detecting nucleosomes containing histone variants
GB201115095D0 (en) * 2011-09-01 2011-10-19 Singapore Volition Pte Ltd Method for detecting nucleosomes containing nucleotides
EP4092415A1 (en) * 2011-12-07 2022-11-23 Belgian Volition Srl Method for detecting nucleosome adducts

Patent Citations (1)

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Publication number Priority date Publication date Assignee Title
US20160003848A1 (en) 2013-02-28 2016-01-07 Singapore Volition Pte Limited Method for predicting therapy efficacy using nucleosome structure biomarkers

Non-Patent Citations (2)

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Title
Ballare Cecilia et al, Molecular Cell (2012.11.21.), vol 49, no 1, pp 67-79.
Paschalia Pantazi et al, Research and Reports in Biochemistry (2015.01.13.), 2015: 5, pp 11-30.

Also Published As

Publication number Publication date
EP3839513B1 (en) 2023-06-14
US20200363418A1 (en) 2020-11-19
WO2017162755A1 (en) 2017-09-28
KR102369544B1 (ko) 2022-03-03
EP3839513C0 (en) 2023-06-14
EP3839513A1 (en) 2021-06-23
EP4270007A2 (en) 2023-11-01
AU2017238442A1 (en) 2018-10-11
JP6777757B2 (ja) 2020-10-28
CN109313192A (zh) 2019-02-05
KR20210049954A (ko) 2021-05-06
KR20190013707A (ko) 2019-02-11
EP3433616A1 (en) 2019-01-30
EP3433616B2 (en) 2024-07-24
ES2951136T3 (es) 2023-10-18
MY187655A (en) 2021-10-07
SG11201807991QA (en) 2018-10-30
EP3433616B1 (en) 2020-12-30
CN109313192B (zh) 2022-07-26
GB201604806D0 (en) 2016-05-04
EP4270007A3 (en) 2023-12-20
CA3018428A1 (en) 2017-09-28
CA3018428C (en) 2024-03-19
JP2019510974A (ja) 2019-04-18
ES2861440T3 (es) 2021-10-06
ES2861440T5 (en) 2025-02-05

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