KR102240473B1 - 방법, 어레이 및 그의 용도 - Google Patents

방법, 어레이 및 그의 용도 Download PDF

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KR102240473B1
KR102240473B1 KR1020167015574A KR20167015574A KR102240473B1 KR 102240473 B1 KR102240473 B1 KR 102240473B1 KR 1020167015574 A KR1020167015574 A KR 1020167015574A KR 20167015574 A KR20167015574 A KR 20167015574A KR 102240473 B1 KR102240473 B1 KR 102240473B1
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KR20160085327A (ko
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칼 아르네 크리스테르 보레바에크
크리스테르 라르스 베르틸 빈그렌
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이뮤노비아 에이비
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    • G01N33/57438
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57525Immunoassay; Biospecific binding assay; Materials therefor for cancer of the liver or pancreas
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6834Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • G01N33/54386Analytical elements
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/581Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with enzyme label (including co-enzymes, co-factors, enzyme inhibitors or substrates)
    • CCHEMISTRY; METALLURGY
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    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Peptides Or Proteins (AREA)
KR1020167015574A 2013-11-11 2014-11-11 방법, 어레이 및 그의 용도 Expired - Fee Related KR102240473B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1319878.3 2013-11-11
GBGB1319878.3A GB201319878D0 (en) 2013-11-11 2013-11-11 Method, Array and use thereof
PCT/GB2014/053340 WO2015067969A2 (en) 2013-11-11 2014-11-11 Method, array and use thereof

Publications (2)

Publication Number Publication Date
KR20160085327A KR20160085327A (ko) 2016-07-15
KR102240473B1 true KR102240473B1 (ko) 2021-04-15

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Country Link
US (3) US20160252513A1 (enExample)
EP (1) EP3069143B1 (enExample)
JP (1) JP6600637B2 (enExample)
KR (1) KR102240473B1 (enExample)
CN (1) CN105917230B (enExample)
AU (1) AU2014345484B2 (enExample)
BR (1) BR112016010510A2 (enExample)
CA (1) CA2930211A1 (enExample)
ES (1) ES2704888T3 (enExample)
GB (1) GB201319878D0 (enExample)
MX (1) MX2016006125A (enExample)
WO (1) WO2015067969A2 (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2442919T3 (es) 2007-03-27 2014-02-14 Immunovia Ab Firma/marcadores de proteínas para la detección de adenocarcinoma
GB201014837D0 (en) 2010-09-07 2010-10-20 Immunovia Ab Biomarker signatures and uses thereof
GB201103726D0 (en) 2011-03-04 2011-04-20 Immunovia Ab Method, array and use thereof
CN105021825B (zh) * 2015-07-09 2016-08-17 陈勇 一种检测胰腺癌相关多肽dap44的elisa试剂盒
GB201516801D0 (en) 2015-09-22 2015-11-04 Immunovia Ab Method, array and use thereof
GB201608192D0 (en) * 2016-05-10 2016-06-22 Immunovia Ab Method, array and use thereof
GB201609951D0 (en) * 2016-06-07 2016-07-20 Immunovia Ab Biomarkers signatures and uses thereof
GB201609950D0 (en) * 2016-06-07 2016-07-20 Immunovia Ab Biomarkers signatures and uses thereof
CN110402393A (zh) * 2016-11-24 2019-11-01 休伯特保健公司 疾病诊断的组合物
GB201701572D0 (en) * 2017-01-31 2017-03-15 Immunovia Ab Methods, arrays and uses thereof
KR102536314B1 (ko) * 2018-05-23 2023-05-25 주식회사 휴벳바이오 질환의 진단용 조성물
US11487739B2 (en) 2019-02-19 2022-11-01 Nasdaq, Inc. System and methods for data model detection and surveillance
WO2020223705A2 (en) * 2019-05-02 2020-11-05 Ligandal, Inc. Methods and compositions for diagnostically-responsive ligand-targeted delivery of therapeutic agents
WO2020235943A1 (ko) * 2019-05-21 2020-11-26 (주)아큐레시스바이오 암의 진단용 조성물
GB202010970D0 (en) 2020-07-16 2020-09-02 Immunovia Ab Methods, arrays and uses thereof
KR102226826B1 (ko) * 2020-08-06 2021-03-11 주식회사 휴벳바이오 버피 코트 시료에 사용하기 위한 췌장암 진단용 조성물

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010527232A (ja) * 2007-04-13 2010-08-12 オーエスアイ・ファーマスーティカルズ・インコーポレーテッド 上皮増殖因子受容体キナーゼ阻害剤に対する抗癌反応を予測する生物学的マーカー

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0039578B1 (en) 1980-05-02 1985-04-10 Edward P. Davis Leg aid device
US4486530A (en) 1980-08-04 1984-12-04 Hybritech Incorporated Immunometric assays using monoclonal antibodies
US4376110A (en) 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
US5856090A (en) 1994-09-09 1999-01-05 The Scripps Research Institute DNA-methylase linking reaction
GB9703369D0 (en) 1997-02-18 1997-04-09 Lindqvist Bjorn H Process
US6727066B2 (en) * 2000-07-28 2004-04-27 Incyte Corporation Genes expressed in treated human C3A liver cell cultures
WO2003087766A2 (en) * 2002-04-05 2003-10-23 The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services Methods of diagnosing potential for metastasis or developing hepatocellular carcinoma and of identifying therapeutic targets
JP4679149B2 (ja) * 2002-09-30 2011-04-27 オンコセラピー・サイエンス株式会社 ヒト膵癌に関連する遺伝子およびポリペプチド
US7250496B2 (en) * 2002-11-14 2007-07-31 Rosetta Genomics Ltd. Bioinformatically detectable group of novel regulatory genes and uses thereof
US7217807B2 (en) * 2002-11-26 2007-05-15 Rosetta Genomics Ltd Bioinformatically detectable group of novel HIV regulatory genes and uses thereof
US20050100543A1 (en) * 2003-07-01 2005-05-12 Immunomedics, Inc. Multivalent carriers of bi-specific antibodies
SI1753871T1 (sl) * 2004-05-28 2016-01-29 Agensys, Inc. Protitelesa in sorodne molekule, ki se vežejo na psca proteine
WO2006110585A2 (en) * 2005-04-07 2006-10-19 Novartis Vaccines And Diagnostics Inc. Cancer-related genes (prlr)
JP2007051880A (ja) * 2005-08-15 2007-03-01 Tokyo Univ Of Science 膵臓癌の検出方法、膵臓癌の診断キット
NZ593224A (en) * 2006-01-11 2012-10-26 Genomic Health Inc Gene expression markers (fap) for colorectal cancer prognosis
ES2442919T3 (es) * 2007-03-27 2014-02-14 Immunovia Ab Firma/marcadores de proteínas para la detección de adenocarcinoma
CA2691980C (en) * 2007-06-29 2022-05-10 Correlogic Systems, Inc. Predictive markers for ovarian cancer
US7951549B2 (en) * 2008-03-07 2011-05-31 Osi Pharmaceuticals, Inc. Methods for the identification of agents that inhibit mesenchymal-like tumor cells or their formation
GB0815846D0 (en) * 2008-09-01 2008-10-08 Immunovia Ab diagnosis, prognosis and imaging of disease
ES2703714T3 (es) * 2009-03-12 2019-03-12 Cancer Prevention & Cure Ltd Métodos de identificación, evaluación, prevención y terapia de enfermedades pulmonares y kits de los mismos, incluida la identificación, evaluación, prevención y terapia de enfermedades en base al género
WO2011039289A1 (de) * 2009-09-29 2011-04-07 Protagen Ag Markersequenzen für pankreaskrebserkrankungen, pankreaskarzinom und deren verwendung
MY185582A (en) * 2010-01-07 2021-05-24 Malaysian Palm Oil Board Anti-obesity and anti-dyslipidemic effects of oil palm phenolics in preventing atheroslerosis and cardiovascular disease
CN102279264A (zh) * 2010-06-09 2011-12-14 李彬 48种恶性肿瘤标志物抗体芯片的制备方法
US20120040858A1 (en) * 2010-08-13 2012-02-16 Morehouse School Of Medicine Biomarkers for stroke
GB201103726D0 (en) * 2011-03-04 2011-04-20 Immunovia Ab Method, array and use thereof
WO2012139628A1 (en) * 2011-04-11 2012-10-18 Lykera Biomed Sa Coding polypurine hairpins for the treatment of cancer

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010527232A (ja) * 2007-04-13 2010-08-12 オーエスアイ・ファーマスーティカルズ・インコーポレーテッド 上皮増殖因子受容体キナーゼ阻害剤に対する抗癌反応を予測する生物学的マーカー

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
C Wingren et al, Cancer Research (2012.05.15.), vol 72, no 10, pp 2481-2490.
Cho J H et al, Gastroenterology (2008.04.01.), vol 134, no 4, pp A-699.
Frida Pauly et al, Journal of Proteome Research (2013.09.24.), vol 12, no 12, pp 5943-5953.
Fujiwara S I et al, Biochemical and Biophysical Research Communications (2005.12.16.), vol 338, no 2, pp 1256-1262.
Johan ingvarsson et al, Proteomics (2008.06.01.), vol 8, no 11, pp 2211-2219.
Li H et al, Chinese Journal of Cancer Prevention and Treatment (2008.08.), vol 15, no 15, pp 1166-1168.

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Publication number Publication date
AU2014345484B2 (en) 2020-08-27
JP2016537652A (ja) 2016-12-01
EP3069143A2 (en) 2016-09-21
ES2704888T3 (es) 2019-03-20
US20220214344A1 (en) 2022-07-07
GB201319878D0 (en) 2013-12-25
BR112016010510A2 (pt) 2017-12-05
JP6600637B2 (ja) 2019-10-30
WO2015067969A3 (en) 2015-08-06
CN105917230B (zh) 2020-06-16
EP3069143B1 (en) 2018-10-10
MX2016006125A (es) 2016-08-12
US20190128891A1 (en) 2019-05-02
US20160252513A1 (en) 2016-09-01
CN105917230A (zh) 2016-08-31
WO2015067969A2 (en) 2015-05-14
KR20160085327A (ko) 2016-07-15
AU2014345484A1 (en) 2016-06-30
CA2930211A1 (en) 2015-05-14

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