KR102200656B1 - 마이크로스피어를 포함하는 개선된 창상 치료 조성물 - Google Patents

마이크로스피어를 포함하는 개선된 창상 치료 조성물 Download PDF

Info

Publication number
KR102200656B1
KR102200656B1 KR1020157009202A KR20157009202A KR102200656B1 KR 102200656 B1 KR102200656 B1 KR 102200656B1 KR 1020157009202 A KR1020157009202 A KR 1020157009202A KR 20157009202 A KR20157009202 A KR 20157009202A KR 102200656 B1 KR102200656 B1 KR 102200656B1
Authority
KR
South Korea
Prior art keywords
microspheres
wound
pharmaceutical composition
wounds
delete delete
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
KR1020157009202A
Other languages
English (en)
Korean (ko)
Other versions
KR20150082207A (ko
Inventor
블라디미르 리터
메리 클레이만
데보라 하나 바르트펠트
에일론 아스쿨라이
Original Assignee
폴리힐 리미티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 폴리힐 리미티드 filed Critical 폴리힐 리미티드
Publication of KR20150082207A publication Critical patent/KR20150082207A/ko
Application granted granted Critical
Publication of KR102200656B1 publication Critical patent/KR102200656B1/ko
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/745Polymers of hydrocarbons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0014Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061Use of materials characterised by their function or physical properties
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020157009202A 2012-09-13 2013-09-12 마이크로스피어를 포함하는 개선된 창상 치료 조성물 Active KR102200656B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261700362P 2012-09-13 2012-09-13
US61/700,362 2012-09-13
PCT/IL2013/050774 WO2014041543A1 (en) 2012-09-13 2013-09-12 Improved wound healing compositions comprising microspheres

Publications (2)

Publication Number Publication Date
KR20150082207A KR20150082207A (ko) 2015-07-15
KR102200656B1 true KR102200656B1 (ko) 2021-01-11

Family

ID=50277729

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020157009202A Active KR102200656B1 (ko) 2012-09-13 2013-09-12 마이크로스피어를 포함하는 개선된 창상 치료 조성물

Country Status (17)

Country Link
US (1) US9370533B2 (https=)
EP (1) EP2895209B1 (https=)
JP (1) JP6104390B2 (https=)
KR (1) KR102200656B1 (https=)
AU (1) AU2013316718B2 (https=)
BR (1) BR112015005335B1 (https=)
CA (1) CA2883455C (https=)
DK (1) DK2895209T3 (https=)
ES (1) ES2748805T3 (https=)
HR (1) HRP20191804T1 (https=)
HU (1) HUE047212T2 (https=)
LT (1) LT2895209T (https=)
MX (1) MX359713B (https=)
PL (1) PL2895209T3 (https=)
PT (1) PT2895209T (https=)
RS (1) RS59410B1 (https=)
WO (1) WO2014041543A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6893877B2 (ja) * 2014-10-29 2021-06-23 スペクトラル エムディー, インコーポレイテッドSpectral Md, Inc. 組織を分類するための反射モードマルチスペクトル時間分解型光学イメージングの方法および装置
CN110573066A (zh) 2017-03-02 2019-12-13 光谱Md公司 用于多光谱截肢部位分析的机器学习系统和技术
US10740884B2 (en) 2018-12-14 2020-08-11 Spectral Md, Inc. System and method for high precision multi-aperture spectral imaging
KR102812782B1 (ko) 2018-12-14 2025-05-23 스펙트랄 엠디, 인크. 고정밀도 다중-애퍼쳐 스펙트럼 이미징을 위한 시스템 및 방법
KR20240163190A (ko) 2018-12-14 2024-11-18 스펙트랄 엠디, 인크. 상처들의 평가, 치유 예측 및 치료를 위한 머신 학습 시스템들 및 방법들
US10783632B2 (en) 2018-12-14 2020-09-22 Spectral Md, Inc. Machine learning systems and method for assessment, healing prediction, and treatment of wounds
WO2022212413A1 (en) 2021-03-30 2022-10-06 Spectral Md, Inc. System and method for high precision snapshot multi-spectral imaging based on multiplexed illumination

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5614310A (en) * 1994-11-04 1997-03-25 Minnesota Mining And Manufacturing Company Low trauma wound dressing with improved moisture vapor permeability
US5861149A (en) 1997-06-04 1999-01-19 Polyheal Ltd. Methods for wound treatment
KR100683603B1 (ko) * 1998-10-23 2007-02-20 폴리힐 엘티디. 창상 치유용 미소구 조성물
CA2440803A1 (en) * 2001-03-07 2002-09-12 Pfizer Products Inc. Modulators of chemokine receptor activity
US7465463B2 (en) * 2002-09-04 2008-12-16 Polyheal, Ltd. Compositions comprising microspheres with anti-inflammatory properties for healing of ocular tissues
CN101378790A (zh) * 2006-01-31 2009-03-04 大卫·瓦尚 用于促进多细胞生物的组织愈合的组合物和方法
GB0607774D0 (en) * 2006-04-20 2006-05-31 Renovo Group Plc Medicaments

Also Published As

Publication number Publication date
EP2895209A4 (en) 2016-04-20
RS59410B1 (sr) 2019-11-29
HK1212638A1 (en) 2016-06-17
US9370533B2 (en) 2016-06-21
WO2014041543A1 (en) 2014-03-20
BR112015005335A2 (pt) 2017-07-04
PL2895209T3 (pl) 2020-01-31
HRP20191804T1 (hr) 2019-12-27
KR20150082207A (ko) 2015-07-15
JP6104390B2 (ja) 2017-03-29
BR112015005335A8 (pt) 2018-01-30
ES2748805T3 (es) 2020-03-18
EP2895209A1 (en) 2015-07-22
MX359713B (es) 2018-10-08
CA2883455C (en) 2020-01-28
DK2895209T3 (da) 2019-10-21
US20150231170A1 (en) 2015-08-20
JP2015528492A (ja) 2015-09-28
CA2883455A1 (en) 2014-03-20
EP2895209B1 (en) 2019-07-17
HUE047212T2 (hu) 2020-04-28
LT2895209T (lt) 2019-10-25
MX2015002816A (es) 2015-05-15
BR112015005335B1 (pt) 2020-03-10
AU2013316718A1 (en) 2015-03-12
PT2895209T (pt) 2019-10-28
AU2013316718B2 (en) 2016-09-29

Similar Documents

Publication Publication Date Title
KR102200656B1 (ko) 마이크로스피어를 포함하는 개선된 창상 치료 조성물
KR102132543B1 (ko) 양이온성 살생물제를 포함하는 페트롤라툼-계 조성물
Khorasani et al. Aloe versus silver sulfadiazine creams for second-degree burns: a randomized controlled study
JP6778219B2 (ja) 皮膚の炎症を抑制するイガイ接着タンパク質製品及びその適用
JP2021520373A (ja) Cgrpを阻害する際に使用するための神経毒素
JP2019206544A (ja) 次亜塩素酸ナトリウムを含む抗炎症溶液
Cortesi et al. Lipid-based nanosystems for wound healing
US12171901B2 (en) Powdered collagen wound care compositions
Serafini et al. Recent patents on medicinal plants/natural products as a therapeutic approach to wounds and burns healing
EP3087990B1 (en) Gel-forming powder comprising sulfamonomethoxine and chitosan for treating wounds
RU2286781C2 (ru) Способ лечения химических ожогов пищевода у детей
HK1212638B (en) Improved wound healing compositions comprising microspheres
US20250367224A1 (en) Galactose and fucose monosaccharides for re-epithelialization and treating lesions
EP4659751A1 (en) Galactose and fucose monosaccharides for re-epithelialization and treating lesions
CN115245502B (zh) 滴喷剂型纳米脂质体凝胶三伏贴
CN112316108A (zh) 促进及治疗慢性伤口愈合的组合物和方法
KR101607229B1 (ko) 말기름을 함유하는 상처 치료용 조성물
KR102644156B1 (ko) 피부 상처 또는 화상 치료 작용제
Katual et al. Advancements in Treatment of Laceration by Chitosan Coated Flexible Liposomes of Mupirocin: A current prospective
Sar Development and characterisation of metformin loaded film with flaxseed gel for acceleration of healing process of burn wounds: an approach for tissue regeneration
CN117617500A (zh) 一种适用于术后恢复的功能型配方粉及其制备方法和用法
Zagórska-Dziok et al. Hydrogel-Based Active Substance Release Systems for Cosmetology and Dermatology Application: A
Palácio et al. WOUND HEALING EFFECTS OF Β-LAPACHONE-LOADED LIPOSOMAL HYDROGEL BASED ON BACTERIAL CELLULOSE AND HYDROXYETHYLCELLULOSE

Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20150409

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
A201 Request for examination
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20180907

Comment text: Request for Examination of Application

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20200213

Patent event code: PE09021S01D

E701 Decision to grant or registration of patent right
PE0701 Decision of registration

Patent event code: PE07011S01D

Comment text: Decision to Grant Registration

Patent event date: 20201013

GRNT Written decision to grant
PR0701 Registration of establishment

Comment text: Registration of Establishment

Patent event date: 20210105

Patent event code: PR07011E01D

PR1002 Payment of registration fee

Payment date: 20210105

End annual number: 3

Start annual number: 1

PG1601 Publication of registration
PR1001 Payment of annual fee

Payment date: 20231228

Start annual number: 4

End annual number: 4

PR1001 Payment of annual fee

Payment date: 20241226

Start annual number: 5

End annual number: 5