KR102137717B1 - 채널로돕신-2 (chop2) 돌연변이의 확인 및 사용 방법 - Google Patents

채널로돕신-2 (chop2) 돌연변이의 확인 및 사용 방법 Download PDF

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KR102137717B1
KR102137717B1 KR1020147027985A KR20147027985A KR102137717B1 KR 102137717 B1 KR102137717 B1 KR 102137717B1 KR 1020147027985 A KR1020147027985 A KR 1020147027985A KR 20147027985 A KR20147027985 A KR 20147027985A KR 102137717 B1 KR102137717 B1 KR 102137717B1
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KR20140132401A (ko
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주오-화 팬
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웨인 스테이트 유니버시티
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/405—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from algae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

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  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
KR1020147027985A 2012-03-05 2013-03-05 채널로돕신-2 (chop2) 돌연변이의 확인 및 사용 방법 Active KR102137717B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261606663P 2012-03-05 2012-03-05
US61/606,663 2012-03-05
PCT/US2013/029171 WO2013134295A1 (en) 2012-03-05 2013-03-05 Identification of channelrhodopsin-2 (chop2) mutations and methods of use

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KR20140132401A KR20140132401A (ko) 2014-11-17
KR102137717B1 true KR102137717B1 (ko) 2020-07-27

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US (3) US10947281B2 (enExample)
EP (1) EP2822964B1 (enExample)
JP (3) JP6395611B2 (enExample)
KR (1) KR102137717B1 (enExample)
CN (2) CN111378020A (enExample)
AU (4) AU2013230112A1 (enExample)
CA (1) CA2866405A1 (enExample)
DK (1) DK2822964T3 (enExample)
EA (1) EA201491643A1 (enExample)
ES (1) ES2703324T3 (enExample)
HU (1) HUE040487T2 (enExample)
MX (1) MX360085B (enExample)
NZ (1) NZ629843A (enExample)
PL (1) PL2822964T3 (enExample)
PT (1) PT2822964T (enExample)
WO (1) WO2013134295A1 (enExample)

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US8470790B2 (en) 2006-05-04 2013-06-25 Wayne State University Restoration of visual responses by in vivo delivery of rhodopsin nucleic acids
US9453241B2 (en) 2010-05-04 2016-09-27 Wayne State University AAV-mediated subcellular targeting of heterologous rhodopsins in retinal ganglion cells
CN111378020A (zh) 2012-03-05 2020-07-07 韦恩州立大学 通道视蛋白-2(Chop2)突变的鉴定及使用方法
WO2014160281A2 (en) 2013-03-14 2014-10-02 Wayne State University Method of enhancing delivery of therapeutic compounds to the eye
US10234761B2 (en) 2013-07-08 2019-03-19 Basf Se Oxime ester photoinitiators
WO2015138616A1 (en) 2014-03-11 2015-09-17 Wayne State University A modified mglur6 promoter and methods of use
KR20230160967A (ko) 2016-05-03 2023-11-24 웨인 스테이트 유니버시티 프로테오좀 억제제를 사용하여 눈에서 바이러스 매개 유전자 전달을 향상시키는 방법
JP2019522469A (ja) * 2016-06-03 2019-08-15 マックス−プランク−ゲゼルシャフト ツア フェルデルンク デア ヴィッセンシャフテン エー．ファウ． チャネルロドプシンの変異型光誘導性イオンチャネル
RU2019109021A (ru) * 2016-08-29 2020-09-29 Уэйн Стейт Юниверсити Идентификация мутаций в вариантах каналопсина, имеющих улучшенную чувствительность к свету, и способы их применения
WO2018106369A2 (en) * 2016-11-06 2018-06-14 Nanoscope Technologies Llc Optogenetic modulation by multi-characteristic opsins for vision restoration and other applications thereof
WO2018189247A1 (en) * 2017-04-12 2018-10-18 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. New optogenetic tool
SG11202004940VA (en) * 2017-12-04 2020-06-29 Salvat Lab Sa Ophthalmic topical composition comprising dobesilic acid for treating diseases of the posterior segment of the eye
JP6567153B1 (ja) * 2018-09-28 2019-08-28 学校法人東北工業大学 対象化合物の特性の予測を行うための方法、コンピュータシステム、プログラム
WO2024226667A2 (en) * 2023-04-24 2024-10-31 Nanoscope Therapeutics Inc. Optogenetic modulation by multi-characteristic opsins for vision restoration and other applications thereof

Citations (1)

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KR101639859B1 (ko) 2014-03-06 2016-07-14 포항공과대학교 산학협력단 광 자극에 의한 미토콘드리아 활성의 시공간적 가역 조절 방법

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US4498919A (en) 1983-10-31 1985-02-12 Corning Glass Works Method for making colored photochromic prescription ophthalmic lenses
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WO2000015822A1 (en) 1998-09-17 2000-03-23 University Of Florida Methods for treatment of degenerative retinal diseases
CA2406743A1 (en) 2000-04-28 2001-11-08 The Trustees Of The University Of Pennsylvania Recombinant aav vectors with aav5 capsids and aav5 vectors pseudotyped in heterologous capsids
EP1381276A4 (en) 2001-04-13 2005-02-02 Univ Pennsylvania METHOD FOR TREATMENT OR DEVELOPMENT SLUDGE DEGRADATION
WO2003016486A2 (en) 2001-08-16 2003-02-27 Sloan Kettering Institute For Cancer Research Bio-synthetic photostimulators and methods of use
DE10216005A1 (de) 2002-04-11 2003-10-30 Max Planck Gesellschaft Verwendung von biologischen Photorezeptoren als direkt lichtgesteuerte Ionenkanäle
WO2004009022A2 (en) 2002-07-18 2004-01-29 The General Hospital Corp. Method for augmenting vision in persons suffering from photoreceptor cell degeneration
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US20070053996A1 (en) 2005-07-22 2007-03-08 Boyden Edward S Light-activated cation channel and uses thereof
US8470790B2 (en) * 2006-05-04 2013-06-25 Wayne State University Restoration of visual responses by in vivo delivery of rhodopsin nucleic acids
US9453241B2 (en) 2010-05-04 2016-09-27 Wayne State University AAV-mediated subcellular targeting of heterologous rhodopsins in retinal ganglion cells
SI2614079T1 (sl) * 2010-09-08 2015-10-30 Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften E.V. Mutantski kanalnirodopsin 2
CN111378020A (zh) * 2012-03-05 2020-07-07 韦恩州立大学 通道视蛋白-2(Chop2)突变的鉴定及使用方法

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Also Published As

Publication number Publication date
HK1205744A1 (en) 2015-12-24
EA201491643A1 (ru) 2015-02-27
HUE040487T2 (hu) 2019-03-28
PL2822964T3 (pl) 2019-05-31
CA2866405A1 (en) 2013-09-12
AU2021245195B2 (en) 2023-09-28
JP2019193656A (ja) 2019-11-07
AU2017239601B2 (en) 2019-05-16
NZ727041A (en) 2022-01-28
MX2014010664A (es) 2015-03-06
AU2017239601A1 (en) 2017-10-26
EP2822964B1 (en) 2018-08-22
CN104334575A (zh) 2015-02-04
NZ629843A (en) 2017-03-31
AU2013230112A1 (en) 2014-09-25
CN111378020A (zh) 2020-07-07
US20150044181A1 (en) 2015-02-12
AU2021245195A1 (en) 2021-11-04
WO2013134295A1 (en) 2013-09-12
US10947281B2 (en) 2021-03-16
DK2822964T3 (en) 2018-12-10
EP2822964A1 (en) 2015-01-14
ES2703324T3 (es) 2019-03-08
US20220033449A1 (en) 2022-02-03
JP2015510759A (ja) 2015-04-13
KR20140132401A (ko) 2014-11-17
MX360085B (es) 2018-10-10
JP6395611B2 (ja) 2018-09-26
JP2018134098A (ja) 2018-08-30
PT2822964T (pt) 2018-11-29
AU2019216638B2 (en) 2021-07-08
US20250066431A1 (en) 2025-02-27
AU2019216638A1 (en) 2019-09-05

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