KR101991457B1 - 다가 협막 다당류-운반 단백질을 포함하는 조성물 및 이의 용도 - Google Patents
다가 협막 다당류-운반 단백질을 포함하는 조성물 및 이의 용도 Download PDFInfo
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- KR101991457B1 KR101991457B1 KR1020170111180A KR20170111180A KR101991457B1 KR 101991457 B1 KR101991457 B1 KR 101991457B1 KR 1020170111180 A KR1020170111180 A KR 1020170111180A KR 20170111180 A KR20170111180 A KR 20170111180A KR 101991457 B1 KR101991457 B1 KR 101991457B1
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- South Korea
- Prior art keywords
- protein
- capsular polysaccharide
- serotypes
- vaccine
- capsular
- Prior art date
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- 239000001103 potassium chloride Substances 0.000 description 1
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- 239000002244 precipitate Substances 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
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- 229910000162 sodium phosphate Inorganic materials 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 229940035044 sorbitan monolaurate Drugs 0.000 description 1
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- 238000010561 standard procedure Methods 0.000 description 1
- 125000004079 stearyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
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- 208000022218 streptococcal pneumonia Diseases 0.000 description 1
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Classifications
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55516—Proteins; Peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020160114591 | 2016-09-06 | ||
| KR20160114591 | 2016-09-06 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20180027353A KR20180027353A (ko) | 2018-03-14 |
| KR101991457B1 true KR101991457B1 (ko) | 2019-09-30 |
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| Application Number | Title | Priority Date | Filing Date |
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| KR1020170111180A KR101991457B1 (ko) | 2016-09-06 | 2017-08-31 | 다가 협막 다당류-운반 단백질을 포함하는 조성물 및 이의 용도 |
Country Status (12)
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| KR (1) | KR101991457B1 (ar) |
| BR (1) | BR112019004303A2 (ar) |
| EA (1) | EA201990451A1 (ar) |
| JO (1) | JOP20190038B1 (ar) |
| MA (1) | MA45283B1 (ar) |
| MX (1) | MX2019002552A (ar) |
| MY (1) | MY192792A (ar) |
| PH (1) | PH12019500377A1 (ar) |
| SA (1) | SA519401232B1 (ar) |
| TN (1) | TN2019000064A1 (ar) |
| WO (1) | WO2018048141A1 (ar) |
| ZA (1) | ZA201901969B (ar) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7369123B2 (ja) | 2017-12-06 | 2023-10-25 | メルク・シャープ・アンド・ドーム・エルエルシー | 肺炎球菌多糖類－タンパク質コンジュゲートを含む組成物およびその使用方法 |
| US11123417B2 (en) | 2018-02-05 | 2021-09-21 | Sanofi Pasteur Inc. | Multivalent pneumococcal polysaccharide-protein conjugate composition |
| AU2019256218A1 (en) * | 2018-04-18 | 2020-12-03 | Sk Bioscience Co., Ltd. | Streptococcus pneumoniae capsular polysaccharides and immunogenic conjugate thereof |
| MA54533A (fr) | 2018-12-19 | 2022-03-30 | Merck Sharp & Dohme | Compositions comprenant des conjugués polysaccharide-protéine de streptococcus pneumoniae et leurs méthodes d'utilisation |
| WO2023218322A1 (en) * | 2022-05-11 | 2023-11-16 | Pfizer Inc. | Process for producing of vaccine formulations with preservatives |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2015175355A1 (en) * | 2014-05-11 | 2015-11-19 | Kanvax Biopharmaceuticals Ltd | Compositions and methods of enhancing immunogenicity of polysaccharide protein conjugates |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE254475T1 (de) * | 1993-09-22 | 2003-12-15 | Jackson H M Found Military Med | Verfahren zur aktivierung von löslichem kohlenhydraten durch verwendung von neuen cyanylierungsreagenzien, zur herstellung von immunogenischen konstrukten |
| CN102716480B (zh) * | 2005-04-08 | 2023-03-21 | 惠氏有限责任公司 | 多价肺炎球菌多糖-蛋白质缀合物组合物 |
| SI3170508T1 (sl) * | 2010-06-04 | 2020-01-31 | Wyeth Llc | Formulacije cepiva |
| KR102057217B1 (ko) * | 2012-06-20 | 2020-01-22 | 에스케이바이오사이언스 주식회사 | 다가 폐렴구균 다당류-단백질 접합체 조성물 |
| CN103893751B (zh) * | 2014-03-26 | 2016-04-20 | 天津康希诺生物技术有限公司 | 一种肺炎球菌多糖蛋白缀合疫苗及其制备方法 |
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2017
- 2017-08-31 BR BR112019004303A patent/BR112019004303A2/pt unknown
- 2017-08-31 JO JOP/2019/0038A patent/JOP20190038B1/ar active
- 2017-08-31 EA EA201990451A patent/EA201990451A1/ru unknown
- 2017-08-31 TN TNP/2019/000064A patent/TN2019000064A1/en unknown
- 2017-08-31 MY MYPI2019001207A patent/MY192792A/en unknown
- 2017-08-31 MX MX2019002552A patent/MX2019002552A/es unknown
- 2017-08-31 MA MA45283A patent/MA45283B1/fr unknown
- 2017-08-31 KR KR1020170111180A patent/KR101991457B1/ko active IP Right Grant
- 2017-08-31 WO PCT/KR2017/009569 patent/WO2018048141A1/ko active Application Filing
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2019
- 2019-02-21 PH PH12019500377A patent/PH12019500377A1/en unknown
- 2019-03-04 SA SA519401232A patent/SA519401232B1/ar unknown
- 2019-03-29 ZA ZA2019/01969A patent/ZA201901969B/en unknown
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015175355A1 (en) * | 2014-05-11 | 2015-11-19 | Kanvax Biopharmaceuticals Ltd | Compositions and methods of enhancing immunogenicity of polysaccharide protein conjugates |
Also Published As
| Publication number | Publication date |
|---|---|
| JOP20190038B1 (ar) | 2023-09-17 |
| EA201990451A1 (ru) | 2019-08-30 |
| MA45283A1 (fr) | 2019-06-28 |
| KR20180027353A (ko) | 2018-03-14 |
| WO2018048141A1 (ko) | 2018-03-15 |
| ZA201901969B (en) | 2019-12-18 |
| BR112019004303A2 (pt) | 2019-05-28 |
| JOP20190038A1 (ar) | 2019-03-06 |
| MX2019002552A (es) | 2019-07-01 |
| TN2019000064A1 (en) | 2020-07-15 |
| PH12019500377A1 (en) | 2019-10-21 |
| SA519401232B1 (ar) | 2022-10-23 |
| MY192792A (en) | 2022-09-09 |
| MA45283B1 (fr) | 2021-05-31 |
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