JOP20190038A1 - تركيب اقتراني من السكر المتعدد لكبسولة بكتيريا المكورات الرئوية وبروتين حامل واستخداماته - Google Patents

تركيب اقتراني من السكر المتعدد لكبسولة بكتيريا المكورات الرئوية وبروتين حامل واستخداماته

Info

Publication number
JOP20190038A1
JOP20190038A1 JOP/2019/0038A JOP20190038A JOP20190038A1 JO P20190038 A1 JOP20190038 A1 JO P20190038A1 JO P20190038 A JOP20190038 A JO P20190038A JO P20190038 A1 JOP20190038 A1 JO P20190038A1
Authority
JO
Jordan
Prior art keywords
carrier protein
capsular polysaccharide
composition
protein conjugates
pneumococcal capsular
Prior art date
Application number
JOP/2019/0038A
Other languages
English (en)
Inventor
Tae Hyun Kim
Hoon Sung Jeh
Original Assignee
Lg Chemical Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lg Chemical Ltd filed Critical Lg Chemical Ltd
Publication of JOP20190038A1 publication Critical patent/JOP20190038A1/ar
Application granted granted Critical
Publication of JOP20190038B1 publication Critical patent/JOP20190038B1/ar

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55516—Proteins; Peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)

Abstract

يتعلق هذا الاختراع بتركيب لقاح لمنع الأمراض التي تحدث بسبب بكتيريا المكورات الرئوية وتركيب منشط للمناعة موجه ضد ستربتوكوكس بنيومونيا ، والذي يحتوي على عدد 13 أو 14 نوعا من اقتران يتكون من سكر متعدد يخص الكبسولة البكتيرية- وبروتين حامل.
JOP/2019/0038A 2016-09-06 2017-08-31 تركيب اقتراني من السكر المتعدد لكبسولة بكتيريا المكورات الرئوية وبروتين حامل واستخداماته JOP20190038B1 (ar)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20160114591 2016-09-06
PCT/KR2017/009569 WO2018048141A1 (ko) 2016-09-06 2017-08-31 다가 협막 다당류-운반 단백질을 포함하는 조성물 및 이의 용도

Publications (2)

Publication Number Publication Date
JOP20190038A1 true JOP20190038A1 (ar) 2019-03-06
JOP20190038B1 JOP20190038B1 (ar) 2023-09-17

Family

ID=61561397

Family Applications (1)

Application Number Title Priority Date Filing Date
JOP/2019/0038A JOP20190038B1 (ar) 2016-09-06 2017-08-31 تركيب اقتراني من السكر المتعدد لكبسولة بكتيريا المكورات الرئوية وبروتين حامل واستخداماته

Country Status (12)

Country Link
KR (1) KR101991457B1 (ar)
BR (1) BR112019004303A2 (ar)
EA (1) EA201990451A1 (ar)
JO (1) JOP20190038B1 (ar)
MA (1) MA45283B1 (ar)
MX (1) MX2019002552A (ar)
MY (1) MY192792A (ar)
PH (1) PH12019500377A1 (ar)
SA (1) SA519401232B1 (ar)
TN (1) TN2019000064A1 (ar)
WO (1) WO2018048141A1 (ar)
ZA (1) ZA201901969B (ar)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3720483A2 (en) 2017-12-06 2020-10-14 Merck Sharp&Dohme Corp. Compositions comprising streptococcus pneumoniae polysaccharide-protein conjugates and methods of use thereof
IL304977A (en) 2018-02-05 2023-10-01 Sanofi Pasteur Inc A multivalent pneumococcal protein-polysaccharide conjugate preparation
BR112020021296A2 (pt) 2018-04-18 2021-01-26 Sk Bioscience Co., Ltd. polissacarídeo capsular de streptococcus pneumoniae e conjugado imunogênico do mesmo
CR20210333A (es) 2018-12-19 2021-08-18 Merck Sharp & Dohme Composiciones que comprenden conjugados de polisacárido de streptococcus pneumoniae con proteína y sus métodos de uso
WO2023218322A1 (en) * 2022-05-11 2023-11-16 Pfizer Inc. Process for producing of vaccine formulations with preservatives

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3828145B2 (ja) * 1993-09-22 2006-10-04 ヘンリー エム．ジャクソン ファウンデイション フォー ザ アドバンスメント オブ ミリタリー メディスン 免疫原性構成物の製造のための新規シアン化試薬を使った可溶性炭水化物の活性化方法
CN104815327A (zh) * 2005-04-08 2015-08-05 惠氏有限责任公司 多价肺炎球菌多糖-蛋白质缀合物组合物
HUE048398T2 (hu) * 2010-06-04 2020-07-28 Wyeth Llc Vakcinakészítmények
KR102057217B1 (ko) * 2012-06-20 2020-01-22 에스케이바이오사이언스 주식회사 다가 폐렴구균 다당류-단백질 접합체 조성물
CN103893751B (zh) * 2014-03-26 2016-04-20 天津康希诺生物技术有限公司 一种肺炎球菌多糖蛋白缀合疫苗及其制备方法
CN104069504B (zh) * 2014-05-11 2019-09-24 江苏康泰生物医学技术有限公司 一种增强多糖蛋白结合物免疫原性的方法

Also Published As

Publication number Publication date
SA519401232B1 (ar) 2022-10-23
MA45283B1 (fr) 2021-05-31
MX2019002552A (es) 2019-07-01
PH12019500377A1 (en) 2019-10-21
KR20180027353A (ko) 2018-03-14
MY192792A (en) 2022-09-09
TN2019000064A1 (en) 2020-07-15
WO2018048141A1 (ko) 2018-03-15
BR112019004303A2 (pt) 2019-05-28
KR101991457B1 (ko) 2019-09-30
JOP20190038B1 (ar) 2023-09-17
ZA201901969B (en) 2019-12-18
EA201990451A1 (ru) 2019-08-30
MA45283A1 (fr) 2019-06-28

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