EA201990451A1 - Композиция многовалентных пневмококковых конъюгатов капсульного полисахарида с белком-носителем и ее применение - Google Patents

Композиция многовалентных пневмококковых конъюгатов капсульного полисахарида с белком-носителем и ее применение

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Publication number
EA201990451A1
EA201990451A1 EA201990451A EA201990451A EA201990451A1 EA 201990451 A1 EA201990451 A1 EA 201990451A1 EA 201990451 A EA201990451 A EA 201990451A EA 201990451 A EA201990451 A EA 201990451A EA 201990451 A1 EA201990451 A1 EA 201990451A1
Authority
EA
Eurasian Patent Office
Prior art keywords
composition
protein
pneumo
valent
cock
Prior art date
Application number
EA201990451A
Other languages
English (en)
Inventor
Тэ Хён Ким
Хун Сон Чже
Original Assignee
ЭлДжи КЕМ, ЛТД.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ЭлДжи КЕМ, ЛТД. filed Critical ЭлДжи КЕМ, ЛТД.
Publication of EA201990451A1 publication Critical patent/EA201990451A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55516—Proteins; Peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Изобретение относится к вакцинной композиции для предупреждения пневмококковых заболеваний и к иммуногенной композиции против Streptococcus pneumoniae, которая содержит 13 или 14 типов конъюгатов капсульного полисахарида с белком-носителем.
EA201990451A 2016-09-06 2017-08-31 Композиция многовалентных пневмококковых конъюгатов капсульного полисахарида с белком-носителем и ее применение EA201990451A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20160114591 2016-09-06
PCT/KR2017/009569 WO2018048141A1 (ko) 2016-09-06 2017-08-31 다가 협막 다당류-운반 단백질을 포함하는 조성물 및 이의 용도

Publications (1)

Publication Number Publication Date
EA201990451A1 true EA201990451A1 (ru) 2019-08-30

Family

ID=61561397

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201990451A EA201990451A1 (ru) 2016-09-06 2017-08-31 Композиция многовалентных пневмококковых конъюгатов капсульного полисахарида с белком-носителем и ее применение

Country Status (12)

Country Link
KR (1) KR101991457B1 (ru)
BR (1) BR112019004303A2 (ru)
EA (1) EA201990451A1 (ru)
JO (1) JOP20190038B1 (ru)
MA (1) MA45283B1 (ru)
MX (1) MX2019002552A (ru)
MY (1) MY192792A (ru)
PH (1) PH12019500377A1 (ru)
SA (1) SA519401232B1 (ru)
TN (1) TN2019000064A1 (ru)
WO (1) WO2018048141A1 (ru)
ZA (1) ZA201901969B (ru)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019139692A2 (en) 2017-12-06 2019-07-18 Merck Sharp & Dohme Corp. Compositions comprising streptococcus pneumoniae polysaccharide-protein conjugates and methods of use thereof
CA3089007A1 (en) 2018-02-05 2019-08-08 Sanofi Pasteur Inc. Multivalent pneumococcal polysaccharide-protein conjugate composition
AU2019256218A1 (en) 2018-04-18 2020-12-03 Sk Bioscience Co., Ltd. Streptococcus pneumoniae capsular polysaccharides and immunogenic conjugate thereof
MX2021007496A (es) 2018-12-19 2021-08-05 Merck Sharp & Dohme Llc Composiciones que comprenden conjugados de polisacarido de streptococcus pneumoniae con proteina y sus metodos de uso.
WO2023218322A1 (en) * 2022-05-11 2023-11-16 Pfizer Inc. Process for producing of vaccine formulations with preservatives

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3828145B2 (ja) * 1993-09-22 2006-10-04 ヘンリー エム．ジャクソン ファウンデイション フォー ザ アドバンスメント オブ ミリタリー メディスン 免疫原性構成物の製造のための新規シアン化試薬を使った可溶性炭水化物の活性化方法
EP2425854A1 (en) * 2005-04-08 2012-03-07 Wyeth LLC Multivalent pneumococcal polysaccharide-protein conjugate composition
CN107080838A (zh) * 2010-06-04 2017-08-22 惠氏有限责任公司 疫苗制剂
KR102057217B1 (ko) * 2012-06-20 2020-01-22 에스케이바이오사이언스 주식회사 다가 폐렴구균 다당류-단백질 접합체 조성물
CN103893751B (zh) * 2014-03-26 2016-04-20 天津康希诺生物技术有限公司 一种肺炎球菌多糖蛋白缀合疫苗及其制备方法
CN104069504B (zh) * 2014-05-11 2019-09-24 江苏康泰生物医学技术有限公司 一种增强多糖蛋白结合物免疫原性的方法

Also Published As

Publication number Publication date
JOP20190038A1 (ar) 2019-03-06
KR20180027353A (ko) 2018-03-14
PH12019500377A1 (en) 2019-10-21
MY192792A (en) 2022-09-09
JOP20190038B1 (ar) 2023-09-17
MA45283B1 (fr) 2021-05-31
MX2019002552A (es) 2019-07-01
WO2018048141A1 (ko) 2018-03-15
MA45283A1 (fr) 2019-06-28
SA519401232B1 (ar) 2022-10-23
ZA201901969B (en) 2019-12-18
TN2019000064A1 (en) 2020-07-15
BR112019004303A2 (pt) 2019-05-28
KR101991457B1 (ko) 2019-09-30

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