KR101957530B1 - 치료학적 활성 물질을 포함하는 가습 입자 - Google Patents

치료학적 활성 물질을 포함하는 가습 입자 Download PDF

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Publication number
KR101957530B1
KR101957530B1 KR1020137006737A KR20137006737A KR101957530B1 KR 101957530 B1 KR101957530 B1 KR 101957530B1 KR 1020137006737 A KR1020137006737 A KR 1020137006737A KR 20137006737 A KR20137006737 A KR 20137006737A KR 101957530 B1 KR101957530 B1 KR 101957530B1
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South Korea
Prior art keywords
aerosol
particles
temperature
water vapor
particle
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Expired - Fee Related
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KR1020137006737A
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English (en)
Korean (ko)
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KR20130141463A (ko
Inventor
다니엘라 라멜
프리데만 타우트
뮨크 크리스티안 데
마르쿠스 라스트
페터 이와첸코
게르하르트 폴만
볼프강 코흐
호르스트 빈트
Original Assignee
프라운호퍼-게젤샤프트 추르 푀르데룽 데어 안제반텐 포르슝 에 파우
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A61K9/122—Foams; Dry foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0082—Lung surfactant, artificial mucus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/001—Particle size control
    • A61M11/003—Particle size control by passing the aerosol trough sieves or filters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/10—Preparation of respiratory gases or vapours
    • A61M16/105—Filters
    • A61M16/106—Filters in a path
    • A61M16/1065—Filters in a path in the expiratory path
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/001—Particle size control
    • A61M11/002—Particle size control by flow deviation causing inertial separation of transported particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/06—Respiratory or anaesthetic masks
    • A61M16/0666—Nasal cannulas or tubing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/10—Preparation of respiratory gases or vapours
    • A61M16/14—Preparation of respiratory gases or vapours by mixing different fluids, one of them being in a liquid phase
    • A61M16/142—Preparation of respiratory gases or vapours by mixing different fluids, one of them being in a liquid phase with semi-permeable walls separating the liquid from the respiratory gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/10—Preparation of respiratory gases or vapours
    • A61M16/14—Preparation of respiratory gases or vapours by mixing different fluids, one of them being in a liquid phase
    • A61M16/16—Devices to humidify the respiration air
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/50—General characteristics of the apparatus with microprocessors or computers
    • A61M2205/502—User interfaces, e.g. screens or keyboards
    • A61M2205/505—Touch-screens; Virtual keyboard or keypads; Virtual buttons; Soft keys; Mouse touches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/75—General characteristics of the apparatus with filters
    • A61M2205/7518—General characteristics of the apparatus with filters bacterial
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/0318—Processes

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Emergency Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020137006737A 2010-08-23 2011-08-22 치료학적 활성 물질을 포함하는 가습 입자 Expired - Fee Related KR101957530B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP10173759.1 2010-08-23
EP10173759 2010-08-23
PCT/EP2011/064399 WO2012025496A1 (en) 2010-08-23 2011-08-22 Humidified particles comprising a therapeutically active substance

Publications (2)

Publication Number Publication Date
KR20130141463A KR20130141463A (ko) 2013-12-26
KR101957530B1 true KR101957530B1 (ko) 2019-03-12

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KR1020137006737A Expired - Fee Related KR101957530B1 (ko) 2010-08-23 2011-08-22 치료학적 활성 물질을 포함하는 가습 입자

Country Status (15)

Country Link
US (1) US9693955B2 (OSRAM)
EP (1) EP2608769B1 (OSRAM)
JP (1) JP6324069B2 (OSRAM)
KR (1) KR101957530B1 (OSRAM)
CN (1) CN103052380B (OSRAM)
AU (1) AU2011295165B2 (OSRAM)
BR (1) BR112013003597B1 (OSRAM)
CA (1) CA2805602A1 (OSRAM)
EA (1) EA201300255A1 (OSRAM)
ES (1) ES2769576T3 (OSRAM)
IL (1) IL224692A (OSRAM)
MX (1) MX2013001936A (OSRAM)
NZ (1) NZ607358A (OSRAM)
WO (1) WO2012025496A1 (OSRAM)
ZA (1) ZA201300415B (OSRAM)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT507187B1 (de) 2008-10-23 2010-03-15 Helmut Dr Buchberger Inhalator
JP5681819B2 (ja) 2011-02-11 2015-03-11 バットマーク・リミテッド 吸入器コンポーネント
AT510837B1 (de) 2011-07-27 2012-07-15 Helmut Dr Buchberger Inhalatorkomponente
JP6017562B2 (ja) 2011-09-06 2016-11-02 ブリティッシュ アメリカン タバコ （インヴェストメンツ） リミテッドＢｒｉｔｉｓｈ Ａｍｅｒｉｃａｎ Ｔｏｂａｃｃｏ （Ｉｎｖｅｓｔｍｅｎｔｓ） Ｌｉｍｉｔｅｄ 喫煙材の加熱
WO2013034459A1 (en) 2011-09-06 2013-03-14 British American Tobacco (Investments) Limited Heating smokeable material
AT511344B1 (de) 2011-10-21 2012-11-15 Helmut Dr Buchberger Inhalatorkomponente
GB201207039D0 (en) 2012-04-23 2012-06-06 British American Tobacco Co Heating smokeable material
GB2504076A (en) 2012-07-16 2014-01-22 Nicoventures Holdings Ltd Electronic smoking device
GB2504075A (en) 2012-07-16 2014-01-22 Nicoventures Holdings Ltd Electronic smoking device
DE102013001888B4 (de) * 2013-02-02 2017-07-20 Drägerwerk AG & Co. KGaA Vorrichtung und Verfahren zur Bereitstellung eines Atemgasstromes
CN105210291B (zh) 2013-03-15 2018-10-02 维斯普瑞公司 可调滤波器系统、装置以及方法
GB2513639A (en) 2013-05-02 2014-11-05 Nicoventures Holdings Ltd Electronic cigarette
GB2513638A (en) 2013-05-02 2014-11-05 Nicoventures Holdings Ltd Electronic cigarette
GB2513637A (en) 2013-05-02 2014-11-05 Nicoventures Holdings Ltd Electronic cigarette
GB2514893B (en) 2013-06-04 2017-12-06 Nicoventures Holdings Ltd Container
ES2778679T3 (es) 2014-03-05 2020-08-11 Fraunhofer-Gesellschaft zur Förderung der Angewandten Forschung Ev Dispositivo para proporcionar una cantidad constante de aerosol y sistema de control
US11123513B2 (en) 2014-03-05 2021-09-21 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Humidifier for humidifying an aerosol
GB201407426D0 (en) 2014-04-28 2014-06-11 Batmark Ltd Aerosol forming component
GB2528673B (en) 2014-07-25 2020-07-01 Nicoventures Holdings Ltd Aerosol provision system
US20160101246A1 (en) * 2014-10-10 2016-04-14 Solaeromed Inc. Apparatus and methods for producing and delivering a vapour medicament
GB2533135B (en) 2014-12-11 2020-11-11 Nicoventures Holdings Ltd Aerosol provision systems
GB201505595D0 (en) 2015-03-31 2015-05-13 British American Tobacco Co Cartridge for use with apparatus for heating smokeable material
GB201505597D0 (en) 2015-03-31 2015-05-13 British American Tobacco Co Article for use with apparatus for heating smokable material
GB201511349D0 (en) 2015-06-29 2015-08-12 Nicoventures Holdings Ltd Electronic aerosol provision systems
GB201511361D0 (en) 2015-06-29 2015-08-12 Nicoventures Holdings Ltd Electronic vapour provision system
US20170055584A1 (en) 2015-08-31 2017-03-02 British American Tobacco (Investments) Limited Article for use with apparatus for heating smokable material
US11924930B2 (en) 2015-08-31 2024-03-05 Nicoventures Trading Limited Article for use with apparatus for heating smokable material
GB2542838B (en) 2015-10-01 2022-01-12 Nicoventures Trading Ltd Aerosol provision system
US20170119046A1 (en) 2015-10-30 2017-05-04 British American Tobacco (Investments) Limited Apparatus for Heating Smokable Material
EP4706709A3 (en) 2016-04-27 2026-05-20 Nicoventures Trading Ltd ELECTRONIC AEROSOL SUPPLY SYSTEM AND ASSOCIATED SPRAYER
DE102016112822A1 (de) * 2016-07-13 2018-01-18 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Atemgesteuerte Applikation von pulverförmigem Aerosol bei der Beatmung oder Atemunterstützung eines Patienten
CN213642639U (zh) * 2016-10-14 2021-07-09 蒸汽热能公司 用于呼吸治疗单元中的流体循环的系统和蒸气转移系统
BR112019010069A2 (pt) 2016-12-08 2019-08-20 R.P. Scherer Technologies, Llc método para aliviar tensão em carcaças de cápsula para reduzir propensão à ruptura
WO2018127591A1 (en) * 2017-01-06 2018-07-12 INSERM (Institut National de la Santé et de la Recherche Médicale) Jet aerosol dispenser
ES2798399T3 (es) 2017-09-18 2020-12-11 Fraunhofer Ges Forschung Dispositivo para administrar un aerosol humidificado a una interconexión de paciente
CN116115864B (zh) * 2021-11-15 2025-10-21 深圳麦克韦尔科技有限公司 雾化装置
CN115148330B (zh) * 2022-05-24 2023-07-25 中国医学科学院北京协和医院 Pop治疗方案形成方法及系统

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59164724A (ja) 1983-03-10 1984-09-17 Tokyo Tanabe Co Ltd サ−フアクタント及びそれを含有する呼吸窮迫症候群治療剤
US4773410A (en) 1984-10-09 1988-09-27 Transpirator Technologies, Inc. Method and apparatus for the treatment of the respiratory track with vapor-phase water
DE3819988A1 (de) 1988-06-11 1989-12-14 Draegerwerk Ag Atemluftanfeuchter fuer ein atemschutzgeraet
JPH04506809A (ja) 1989-07-11 1992-11-26 ジェネンテク，インコーポレイテッド 界面活性剤組成物および方法
DK0553272T3 (da) 1990-10-17 2000-09-04 Liposome Co Inc Syntetisk lungesurfactant
GB9120005D0 (en) * 1991-09-19 1991-11-06 Wellcome Found Method of administering phospholipid dispersions
US6582728B1 (en) * 1992-07-08 2003-06-24 Inhale Therapeutic Systems, Inc. Spray drying of macromolecules to produce inhaleable dry powders
DE4418936A1 (de) 1994-05-31 1996-02-08 Byk Gulden Lomberg Chem Fab Polypeptid
SE503771C2 (sv) * 1994-12-01 1996-09-02 Gibeck Respiration Ab Anordning vid fukt-värmeväxlare
DE19507410C2 (de) * 1995-03-03 1997-05-22 Gsf Forschungszentrum Umwelt Verfahren und Vorrichtung zur Herstellung von Aerosolen
US6315983B1 (en) 1996-01-24 2001-11-13 Byk Gulden Lomberg Chemische Fabrik Gmbh Process for the production of powdered pulmonary surfactant preparations
US6261539B1 (en) * 1998-12-10 2001-07-17 Akwete Adjei Medicinal aerosol formulation
DE19962221A1 (de) 1999-10-01 2001-05-23 Glatt Process Technology Gmbh Dispersionen für Depotapplikationen
AU782579B2 (en) 1999-12-10 2005-08-11 Vapotherm, Inc. Apparatus and method for respiratory tract therapy
US6918389B2 (en) 2000-03-21 2005-07-19 Fisher & Paykel Healthcare Limited Breathing assistance apparatus
EP1324751B1 (en) 2000-10-02 2006-05-24 Novozymes A/S Coated particles containing an active substance
US7708013B2 (en) 2000-12-08 2010-05-04 Vapotherm, Inc. Apparatus and method for delivering water vapor to a gas
US20080038363A1 (en) * 2001-05-24 2008-02-14 Zaffaroni Alejandro C Aerosol delivery system and uses thereof
WO2003065005A2 (en) 2002-01-30 2003-08-07 Aerosol Dynamics Inc. Continuous, laminar flow water-based particle condensation device and method
US8003080B2 (en) * 2002-05-13 2011-08-23 Alexza Pharmaceuticals, Inc. Delivery of drug amines through an inhalation route
GB0326632D0 (en) * 2003-11-14 2003-12-17 Jagotec Ag Dry powder formulations
US7407531B2 (en) * 2004-05-10 2008-08-05 Tsi Incorporated Particle surface treatment for promoting condensation
DE102005016102B3 (de) 2005-04-08 2006-10-26 Altana Pharma Ag Vorrichtung zur Dosierung und Trockenvernebelung
EP1820530B1 (en) 2006-02-20 2014-10-08 Björn Thulin Humidifier and use of the humidifier
DE102006026578B4 (de) 2006-06-08 2009-01-08 Lts Lohmann Therapie-Systeme Ag Wirkstoffpartikelhaltiges Transdermales Therapeutisches System mit erhöhtem Wirkstofffluss und Verfahren zu seiner Herstellung sowie Verwendung
WO2008036293A1 (en) * 2006-09-19 2008-03-27 Discovery Laboratories, Inc. Pulmonary surfactant formulations and methods for promoting mucus clearance
US8550075B2 (en) 2007-06-28 2013-10-08 Resmed Limited Removable and/or replaceable humidifier
EP2203155A1 (en) 2007-09-25 2010-07-07 Novartis Ag Treatment of pulmonary disorders with aerosolized medicaments such as vancomycin
EP2172190A1 (en) 2008-10-02 2010-04-07 Laboratorios Liconsa, S.A. Inhalable particles comprising tiotropium
NZ620527A (en) 2009-04-23 2015-08-28 Takeda Gmbh Improved apparatus for the aerosolization of large volumes of dry powder

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Respiratory Care, 2005, 50(9), 1209-1227*

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Publication number Publication date
US20130142782A1 (en) 2013-06-06
ZA201300415B (en) 2017-11-29
KR20130141463A (ko) 2013-12-26
ES2769576T3 (es) 2020-06-26
WO2012025496A1 (en) 2012-03-01
CN103052380B (zh) 2015-11-25
EP2608769A1 (en) 2013-07-03
JP6324069B2 (ja) 2018-05-16
US9693955B2 (en) 2017-07-04
IL224692A (en) 2017-12-31
CN103052380A (zh) 2013-04-17
CA2805602A1 (en) 2012-03-01
BR112013003597B1 (pt) 2021-10-13
NZ607358A (en) 2015-04-24
BR112013003597A8 (pt) 2018-02-06
EA201300255A1 (ru) 2013-06-28
AU2011295165A1 (en) 2013-04-04
EP2608769B1 (en) 2019-11-06
AU2011295165B2 (en) 2015-07-02
MX2013001936A (es) 2013-03-08
BR112013003597A2 (pt) 2016-08-16
JP2013540704A (ja) 2013-11-07

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