KR101931392B1 - 세로토닌 수용체 작용제 및 디케토피페라진을 포함하는 편두통 치료용 조성물 - Google Patents

세로토닌 수용체 작용제 및 디케토피페라진을 포함하는 편두통 치료용 조성물 Download PDF

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KR101931392B1
KR101931392B1 KR1020137014686A KR20137014686A KR101931392B1 KR 101931392 B1 KR101931392 B1 KR 101931392B1 KR 1020137014686 A KR1020137014686 A KR 1020137014686A KR 20137014686 A KR20137014686 A KR 20137014686A KR 101931392 B1 KR101931392 B1 KR 101931392B1
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sumatriptan
pharmaceutical composition
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dry powder
diketopiperazine
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KR20140008314A (ko
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안드레아 레온-베이
그레이슨 더블유. 스토웰
조세프 제이. 과르네리
돈 엠. 칼슨
마샬 그랜트
채드 씨. 스머트니
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맨카인드 코포레이션
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4196—1,2,4-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020137014686A 2010-11-09 2011-11-09 세로토닌 수용체 작용제 및 디케토피페라진을 포함하는 편두통 치료용 조성물 Active KR101931392B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US41177510P 2010-11-09 2010-11-09
US61/411,775 2010-11-09
US41233910P 2010-11-10 2010-11-10
US61/412,339 2010-11-10
PCT/US2011/060057 WO2012064892A1 (en) 2010-11-09 2011-11-09 Composition comprising a serotonin receptor agonist and a diketopiperazine for treating migraines

Publications (2)

Publication Number Publication Date
KR20140008314A KR20140008314A (ko) 2014-01-21
KR101931392B1 true KR101931392B1 (ko) 2018-12-20

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KR1020137014686A Active KR101931392B1 (ko) 2010-11-09 2011-11-09 세로토닌 수용체 작용제 및 디케토피페라진을 포함하는 편두통 치료용 조성물

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EP (2) EP3536368B1 (enExample)
JP (2) JP6092113B2 (enExample)
KR (1) KR101931392B1 (enExample)
CN (2) CN107854454A (enExample)
AU (1) AU2011326529B2 (enExample)
BR (1) BR112013011549B1 (enExample)
CA (1) CA2817337C (enExample)
ES (1) ES2732818T3 (enExample)
MX (2) MX376862B (enExample)
WO (1) WO2012064892A1 (enExample)

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HUE035803T2 (en) 2012-12-21 2018-05-28 Sanofi Sa Dual GLP1 / GIP or trigonal GLP1 / GIP / glucagon agonists
BR112015023168B1 (pt) 2013-03-15 2021-08-10 Mannkind Corporation Composição de 3,6-bis(n-fumaril-4-aminobutil)-2,5-dicetopiperazina cristalina, método de produção de partículas de 3,6-bis(n-fumaril-4-aminobutil)-2,5-dicetopiperazina e uso de uma composição de dicetopiperazina cristalina
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TW201609797A (zh) 2013-12-13 2016-03-16 賽諾菲公司 雙重ｇｌｐ－１／升糖素受體促效劑
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
TW201625669A (zh) 2014-04-07 2016-07-16 賽諾菲公司 衍生自艾塞那肽－４（Ｅｘｅｎｄｉｎ－４）之肽類雙重ＧＬＰ－１／升糖素受體促效劑
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Also Published As

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AU2011326529B2 (en) 2015-07-30
EP3536368B1 (en) 2025-09-17
EP2637657A1 (en) 2013-09-18
BR112013011549A2 (pt) 2017-07-25
JP6092113B2 (ja) 2017-03-08
JP2013545748A (ja) 2013-12-26
AU2011326529A1 (en) 2013-05-02
MX376862B (es) 2025-03-07
CA2817337C (en) 2020-04-14
KR20140008314A (ko) 2014-01-21
CA2817337A1 (en) 2012-05-18
EP3536368A1 (en) 2019-09-11
BR112013011549B1 (pt) 2022-01-04
CN107854454A (zh) 2018-03-30
JP2017110026A (ja) 2017-06-22
CN103200940A (zh) 2013-07-10
EP2637657B1 (en) 2019-05-22
JP6458064B2 (ja) 2019-01-23
WO2012064892A1 (en) 2012-05-18
ES2732818T3 (es) 2019-11-26
MX2013005294A (es) 2013-12-06
MX340112B (es) 2016-06-27

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