KR101912380B9 - 프로바이오틱스의 방출 및 프로바이오틱스 효소 활성의 유지를 위한 점막점착성 장치 - Google Patents

프로바이오틱스의 방출 및 프로바이오틱스 효소 활성의 유지를 위한 점막점착성 장치

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Publication number
KR101912380B9
KR101912380B9 KR1020170032382A KR20170032382A KR101912380B9 KR 101912380 B9 KR101912380 B9 KR 101912380B9 KR 1020170032382 A KR1020170032382 A KR 1020170032382A KR 20170032382 A KR20170032382 A KR 20170032382A KR 101912380 B9 KR101912380 B9 KR 101912380B9
Authority
KR
South Korea
Prior art keywords
probiotics
maintenance
release
enzyme activities
mucoadhesive devices
Prior art date
Application number
KR1020170032382A
Other languages
English (en)
Other versions
KR20180105380A (ko
KR101912380B1 (ko
Inventor
김석진
루피 바바라
비탈리 비아트리체
아브루조 안젤라
Original Assignee
(주)바이오일레븐
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to KR1020170032382A priority Critical patent/KR101912380B1/ko
Application filed by (주)바이오일레븐 filed Critical (주)바이오일레븐
Priority to JP2019572332A priority patent/JP2020510099A/ja
Priority to PCT/KR2018/002968 priority patent/WO2018169296A1/en
Priority to CN201880018644.XA priority patent/CN110461313A/zh
Priority to EP18767740.6A priority patent/EP3595644A4/en
Priority to US16/494,148 priority patent/US11065200B2/en
Publication of KR20180105380A publication Critical patent/KR20180105380A/ko
Application granted granted Critical
Publication of KR101912380B1 publication Critical patent/KR101912380B1/ko
Priority to US17/350,683 priority patent/US20210386659A1/en
Priority to JP2021147594A priority patent/JP7325130B6/ja
Publication of KR101912380B9 publication Critical patent/KR101912380B9/ko

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/745—Bifidobacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/50—Hydrolases (3) acting on carbon-nitrogen bonds, other than peptide bonds (3.5), e.g. asparaginase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0216—Solid or semisolid forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/66—Enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/10—Washing or bathing preparations
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
    • C12Y305/03—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in linear amidines (3.5.3)
    • C12Y305/03006—Arginine deiminase (3.5.3.6)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Birds (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Nutrition Science (AREA)
  • Dermatology (AREA)
  • Physiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Cosmetics (AREA)
KR1020170032382A 2017-03-15 2017-03-15 프로바이오틱스의 방출 및 프로바이오틱스 효소 활성의 유지를 위한 점막점착성 장치 KR101912380B1 (ko)

Priority Applications (8)

Application Number Priority Date Filing Date Title
KR1020170032382A KR101912380B1 (ko) 2017-03-15 2017-03-15 프로바이오틱스의 방출 및 프로바이오틱스 효소 활성의 유지를 위한 점막점착성 장치
PCT/KR2018/002968 WO2018169296A1 (en) 2017-03-15 2018-03-14 Mucoadhesive devices for the release of probiotics and for the maintenance of their enzyme activities
CN201880018644.XA CN110461313A (zh) 2017-03-15 2018-03-14 用于释放益生菌和保持其酶活性的粘膜粘附装置
EP18767740.6A EP3595644A4 (en) 2017-03-15 2018-03-14 MUCOADHESIVE DEVICES FOR THE RELEASE OF PROBIOTICS AND FOR THE MAINTENANCE OF THEIR ENZYMATIC ACTIVITIES
JP2019572332A JP2020510099A (ja) 2017-03-15 2018-03-14 プロバイオティックスの放出およびプロバイオティックス酵素活性の維持のための粘膜粘着性装置
US16/494,148 US11065200B2 (en) 2017-03-15 2018-03-14 Mucoadhesive devices for the release of probiotics and for the maintenance of their enzyme activities
US17/350,683 US20210386659A1 (en) 2017-03-15 2021-06-17 Mucoadhesive devices for the release of probiotics and for the maintenance of their enzyme activities
JP2021147594A JP7325130B6 (ja) 2017-03-15 2021-09-10 プロバイオティックスの放出およびプロバイオティックス酵素活性の維持のための粘膜粘着性フィルムの調製方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1020170032382A KR101912380B1 (ko) 2017-03-15 2017-03-15 프로바이오틱스의 방출 및 프로바이오틱스 효소 활성의 유지를 위한 점막점착성 장치

Publications (3)

Publication Number Publication Date
KR20180105380A KR20180105380A (ko) 2018-09-28
KR101912380B1 KR101912380B1 (ko) 2018-10-26
KR101912380B9 true KR101912380B9 (ko) 2024-01-16

Family

ID=63522300

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020170032382A KR101912380B1 (ko) 2017-03-15 2017-03-15 프로바이오틱스의 방출 및 프로바이오틱스 효소 활성의 유지를 위한 점막점착성 장치

Country Status (6)

Country Link
US (2) US11065200B2 (ko)
EP (1) EP3595644A4 (ko)
JP (2) JP2020510099A (ko)
KR (1) KR101912380B1 (ko)
CN (1) CN110461313A (ko)
WO (1) WO2018169296A1 (ko)

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US11951139B2 (en) 2015-11-30 2024-04-09 Seed Health, Inc. Method and system for reducing the likelihood of osteoporosis
US11951140B2 (en) 2011-02-04 2024-04-09 Seed Health, Inc. Modulation of an individual's gut microbiome to address osteoporosis and bone disease
US11844720B2 (en) 2011-02-04 2023-12-19 Seed Health, Inc. Method and system to reduce the likelihood of dental caries and halitosis
US11826388B2 (en) 2013-12-20 2023-11-28 Seed Health, Inc. Topical application of Lactobacillus crispatus to ameliorate barrier damage and inflammation
US11969445B2 (en) 2013-12-20 2024-04-30 Seed Health, Inc. Probiotic composition and method for controlling excess weight, obesity, NAFLD and NASH
US11839632B2 (en) 2013-12-20 2023-12-12 Seed Health, Inc. Topical application of CRISPR-modified bacteria to treat acne vulgaris
US11833177B2 (en) 2013-12-20 2023-12-05 Seed Health, Inc. Probiotic to enhance an individual's skin microbiome
US11980643B2 (en) 2013-12-20 2024-05-14 Seed Health, Inc. Method and system to modify an individual's gut-brain axis to provide neurocognitive protection
KR101912380B1 (ko) * 2017-03-15 2018-10-26 (주)바이오일레븐 프로바이오틱스의 방출 및 프로바이오틱스 효소 활성의 유지를 위한 점막점착성 장치
US11058634B2 (en) 2018-11-19 2021-07-13 Steven J. Edwards Adherent oral pharmabiotic delivery strip
CN111004757B (zh) * 2019-12-31 2021-11-02 深圳市沁帆科技有限公司 一种罗伊氏乳杆菌、微生物菌剂及食物制品
IT202100001169A1 (it) 2021-01-27 2022-07-27 Alfasigma Spa Gel mucoadesivo buccale contenente probiotici per uso nella prevenzione e nel trattamento delle malattie parodontali.
IT202100023381A1 (it) * 2021-09-09 2023-03-09 Magi Euregio Scs Composizione per il trattamento delle mucositi orali radio-indotte
CN116024128B (zh) * 2022-11-01 2024-05-03 普百氏(北京)生物科技有限公司 一株嗜热链球菌菌株p0012及其制备的口腔健康护理用益生菌组合物和应用
CN115887505B (zh) * 2022-12-30 2024-05-24 北京农学院 动物双歧杆菌j-12干预口腔溃疡的作用效果

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IT1296148B1 (it) * 1996-11-22 1999-06-09 Renata Maria Anna Ve Cavaliere Uso di batteri lattici per accrescere il livello delle ceramidi della pelle e delle mucose, e composizioni dermatologiche e cosmetiche atte
US20050276836A1 (en) * 1997-06-11 2005-12-15 Michelle Wilson Coated vaginal devices for vaginal delivery of therapeutically effective and/or health-promoting agents
US8697051B2 (en) * 1999-06-09 2014-04-15 Vsl Pharmaceuticals Inc. Composition comprising alkaline sphingomyelinase for use as a dietetic preparation, food supplement or pharmaceutical product
KR100654487B1 (ko) 2003-09-09 2006-12-05 마츠시타 덴끼 산교 가부시키가이샤 컨버터 회로, 모터 구동 장치, 압축기, 공기 조화기,냉장고, 전기 세탁기, 송풍기, 전기 청소기 및 히트펌프급탕기
GB0508306D0 (en) * 2005-04-25 2005-06-01 Bioprogress Technology Ltd Nicotine dosage forms
KR101230804B1 (ko) * 2006-07-21 2013-02-08 바이오딜리버리 사이언시스 인터내셔널 인코포레이티드 향상된 흡수를 갖는 경점막 전달 장치
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JP5646158B2 (ja) * 2008-11-07 2014-12-24 ツキオカフィルム製薬株式会社 乳酸菌含有フィルム及び乳酸菌含有フィルムの製造方法
JP2016084287A (ja) * 2014-10-23 2016-05-19 株式会社アヴェデス 歯周病用フィルム状外用剤及びその使用方法
KR101912380B1 (ko) * 2017-03-15 2018-10-26 (주)바이오일레븐 프로바이오틱스의 방출 및 프로바이오틱스 효소 활성의 유지를 위한 점막점착성 장치

Also Published As

Publication number Publication date
EP3595644A1 (en) 2020-01-22
US11065200B2 (en) 2021-07-20
EP3595644A4 (en) 2020-10-21
KR20180105380A (ko) 2018-09-28
KR101912380B1 (ko) 2018-10-26
JP2020510099A (ja) 2020-04-02
US20200078294A1 (en) 2020-03-12
JP2021185205A (ja) 2021-12-09
WO2018169296A1 (en) 2018-09-20
JP7325130B2 (ja) 2023-08-14
JP7325130B6 (ja) 2023-08-29
US20210386659A1 (en) 2021-12-16
CN110461313A (zh) 2019-11-15

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X701 Decision to grant (after re-examination)
GRNT Written decision to grant
G170 Re-publication after modification of scope of protection [patent]