KR101804998B1 - Composition containing natural fermented extracts of ginseng berry - Google Patents

Abstract

The present invention relates to a composition containing a natural fermented extract of ginseng fruit, and more particularly, to a composition containing a fermented extract obtained by naturally fermenting a ginseng fruit having a unique composition and composition among ginseng root parts, Whitening, anti-aging and moisturizing effect.

Description

[0001] The present invention relates to a composition containing natural fermented extract of ginseng fruit,

The present invention relates to a composition containing a natural fermented extract of ginseng fruit, and more particularly, to a composition containing a fermented extract obtained by naturally fermenting a ginseng fruit having a unique composition and composition among ginseng root parts, Whitening, anti-aging and moisturizing effect.

Ginseng (Panax ginseng C.A. Meyer) is a herb that belongs to the genus Ogawa and Ginseng. It has been used in Korea, China and Japan for over 2,000 years and has been used empirically to prevent disease and prolong the life span. The efficacy and effect of ginseng which has been known so far can be determined by the action of the central nervous system, the anticarcinogenic action, the anticancer activity, the immune function regulating action, the anti-diabetic action, the hyperfunction of liver function, the improvement of cardiovascular disorder, (Korean Ginseng & Tobacco Research Institute, 56-112, 1996). In addition, it has been reported that the antioxidant activity and antioxidant activity of osteoporosis are improved.

Ginsenoside, which is a representative physiologically active ingredient of ginseng, is distributed evenly on the ground and underground of ginseng. Especially, ginsenoside (root), ginseng leaf and ginseng berries have not only ginsenoside content but also composition (Attele AS et al, Biochem Pharmacol, 58: 1685-1693, 1999). In particular, the fruit of ginseng has been reported to exhibit superior antidiabetic efficacy to ginseng root based on the contents of ginseng roots and other ginsenosides (Dey L. et al., Phytomedicine, 10, 600 -605, 2003).

Recently, consumers are interested in natural cosmetics. At the same time, many cosmetics using herbal materials have been launched, and ginseng has been studied as a plant material having important skin effect of cosmetics. However, most of them are ginseng root extract or ginseng root ginsenoside Side component and ginseng polysaccharide are utilized only for the inhibition of skin aging and the wrinkle improving effect due to the ingredient of ginseng fruit.

The ginseng fruit is considered to be more valuable than ginseng since ancient times and has been harvested for the purpose of obtaining seeds. Ginseng fruit is grown only once in 4 years of ginseng cultivation period. When seeds are cultivated in 3 year olds, it is difficult to produce good seedling ginseng because seeds are too small. If seeds are grown for 5 years or more, seeds are faithful and good, The quality of red ginseng can be greatly reduced when red ginseng is produced because it is not only inhibited development but also is inadequate in the tissue. When the number of seedlings is increased to more than 2 times during the growing period, the yield and the quality of red ginseng deteriorate significantly (Korean Ginseng and Tobacco Research Institute, 130-131, 1996).

Accordingly, the inventors of the present invention found that natural fermented extract of ginseng fruit has superior skin effect than ordinary ginseng or ginseng fruit extract in studying skin effect using ginseng fruit, which is the above-ground ginseng fruit, and completed the present invention.

Accordingly, an object of the present invention is to provide a composition containing a natural fermented extract of ginseng fruit having skin whitening, anti-aging and moisturizing effect as an active ingredient.

To achieve the above object, the present invention provides a health food or a skin cosmetic composition comprising a natural fermented extract of ginseng fruit as an active ingredient.

The present invention can provide a composition having skin whitening, anti-aging and skin moisturizing effect by containing natural fermented extract of ginseng fruit having ginseng root and different components and composition among ginseng root as an active ingredient. In addition, the present invention is characterized in that the content of active ingredients contained in the ginseng fruit is remarkably increased by naturally fermenting the ginseng fruit without using a separate fermenter and a solvent, so that it can exhibit an excellent effect, is non-irritating, It can be used as a raw material for skin cosmetics.

The present invention provides a health food or skin cosmetic composition comprising a natural fermented extract of ginseng fruit as an active ingredient.

Hereinafter, the present invention will be described more specifically.

The natural fermentation extract of ginseng fruit as an effective ingredient of the present invention can be obtained by removing ginseng fruit to remove impurities and then mixing with sugar components and fermenting without artificial manipulation. The saccharide component usable in the present invention is not particularly limited, and specific examples thereof include sucrose, xylitol, oligosaccharide, dietary fiber, erythritol, glucose, fructose and the like.

The sugar components are mixed with ginseng fruit and placed in pot. At this time, the saccharide ingredient is preferably mixed at 1 to 10 wt% with respect to the total weight of the whole fermentation product, and is fermented for 30 days to 6 years, preferably 6 months or more in a natural environment of sunny four seasons.

The natural fermented extract of the ginseng fruit according to the present invention can be contained as an active ingredient in a health food or cosmetic composition and is excellent in skin whitening, anti-aging and moisturizing effect.

The natural fermented extract of the ginseng fruit of the present invention may be contained in an amount of 0.0001 to 50% by weight based on the total weight of the composition, depending on the form of the composition. If the amount is less than 0.0001% by weight, the effect is insignificant, and if it is more than 50% by weight, the formulation stability is deteriorated.

The health food composition according to the present invention is not particularly limited in its formulation. Specific examples thereof may be oral administration forms such as pills, drinks, tea bags, instant tea, granules, tablets or capsules.

The skin cosmetic composition according to the present invention is not particularly limited in its formulation. Specifically, it may be, for example, a cosmetic composition having a formulation of a softening agent, a nutritional lotion, a nutrient lotion, a massage cream, a nutritional cream, a pack, a gel or a skin adhesive type cosmetic composition, Or spray formulations.

Hereinafter, the constitution and effects of the present invention will be described in more detail with reference to examples and test examples. However, these examples and examples are provided for illustrative purposes only in order to facilitate understanding of the present invention, and the scope and scope of the present invention are not limited by the following examples.

[Preparation Example 1] Preparation of natural fermented extract of ginseng fruit

1kg of washed ginseng fruit was mixed with 50g of oligosaccharide and put into Onggi. When the Onggi was full, it was pressed by pressing it on top of it, and it was naturally fermented for 6 months without covering it. After the fermentation, the fermented raw materials were filtered with a filter cloth to remove the residue, thereby obtaining a natural fermented extract of the ginseng fruit.

[Production Example 2] Preparation of ginseng fruit extract

The raw ginseng fruit was harvested and the seeds were separated and removed. Then, the ginseng fruit and the skin of the ginseng fruit were dried with sunshine or hot air to prepare dry ingredients of ginseng fruit. Next, 3 kg of water was added to 1 kg of dried ginseng fruit, and the mixture was refluxed, filtered and concentrated under reduced pressure at 40 to 45 ° C to obtain 300 g of ginseng fruit extract.

[Manufacturing Example 3] Production of ginseng muscle root extract

In the same manner as in Production Example 2, except that ginseng roots (roots) were used in place of the ginseng fruit in Production Example 2 above.

[Test Example 1] Effect of improving skin wrinkles

For the 30 subjects with facial wrinkles of 30 to 50 years old, the nutritional creams of Examples and Comparative Examples 1 and 2 having the compositions shown in the following Table 1 were produced and their skin wrinkle-reducing effects were compared and evaluated.

ingredient Example
(weight%) Comparative Example 1
(weight%) Comparative Example 2
(weight%) Natural Fermented Extract of Ginseng Fruit (Preparation Example 1) 0.1 - - Ginseng fruit extract (Preparation Example 2) - 0.1 - Ginseng root extract (Preparation Example 3) - - 0.1 Wax 10 10 10 Polysorbate 60 1.5 1.5 1.5 Piggy 60 hardened castor oil 2 2 2 Sorbitan sesquioleate 0.5 0.5 0.5 Liquid paraffin 10 10 10 Squalane 5 5 5 Caprylic / capric triglyceride
(Estasan: Uniqema (manufacturer)) 5 5 5 glycerin 5 5 5 Butylene glycol 3 3 3 Propylene glycol 3 3 3 Triethanolamine 0.2 0.2 0.2 Preservative, coloring, fragrance Suitable amount Suitable amount Suitable amount Purified water Balance Balance Balance

The skin condition of both sides of the facial area before the use of the cream was measured, and then the same part was remeasured 3 months after using the cream to measure the change of the skin wrinkles. The skin wrinkles were measured with a Visiometer system (C + K company) by removing the wrinkles of the eye tail region with a replica in a constant temperature and humidity chamber at 24 ° C and a relative humidity of 40%. The amount of change in the skin wrinkles was calculated according to the following formula (1).

(In the above equation (1), "Tdi" is the measured site value at D90 and "Tdo" is the measured site value at D0)

As a result of calculation according to Equation (1), skin wrinkles at the site using Comparative Example 2 showed a decrease of 6.5 ± 4% (mean ± standard deviation), whereas skin wrinkles at the site using Comparative Example 1 were 13.1 ± 6% The effect of ginseng fruit extract on the skin wrinkle was higher than that of ginseng root extract. However, in the case of the example containing the natural fermentation extract of the ginseng fruit, it showed a decrease value of 35.7 ± 10%. Thus, it was confirmed that the natural fermentation extract of the ginseng fruit according to the present invention improves the skin wrinkles and shows an excellent anti-aging effect.

[Test Example 2] Skin whitening effect

In order to examine the whitening effect of the natural fermented extract of the ginseng fruit on the human skin, the following experiment was conducted using the above-described Examples and Comparative Examples 1 and 2.

First, 12 healthy boys were exposed to UV light (1.5 ~ 2 times UVB) of the minimum erythema (Minimal Erythema Dose) of each subject after attaching an opaque tape with a hole of 1.5 ㎝ in diameter at the upper part of the subject. To induce blackening of the skin.

After the ultraviolet ray irradiation, the test materials of Examples and Comparative Examples 1 and 2 and hydroquinone were applied, respectively, and one state was observed for 10 weeks without applying anything. The color of skin was measured with a colorimeter CR2002 (Minolta Co., Japan) every 1 week.

Then, the difference (ΔL *) between the start time of application of the respective test substances and the completion time of the application of the test substances was calculated according to the following formula 2, and the results are shown in Table 2 below. On the other hand, the whitening effect is judged by comparison of DELTA L * between the sample application site and the control site. When the DELTA L * value is 2, the whitening of the deposited pigment is noticeable. .

Test substance The degree of skin color brightness (DELTA L *) Example 1.89 + 0.17 Comparative Example 1 1.15 ± 0.16 Comparative Example 2 0.62 ± 0.16 Hydroquinone (positive control) 1.90 + 0.13 Vehicle (negative control) 0.50 0.16

As shown in Table 2, the Example containing the naturally fermented extract of the ginseng fruit according to the present invention showed significantly higher skin color brightness as compared with Comparative Examples 1 and 2, and the degree of similarity to the positive control group hydroquinone Of skin color intensity. Therefore, the natural fermented extract of the ginseng fruit according to the present invention improves the pigment deposition caused by ultraviolet rays, thereby brightening the skin color, thereby showing excellent skin whitening effect.

[Test Example 3] Skin moisturizing effect

Sixty adult male and female persons who exhibited dry skin syndrome were divided into three groups, and each group was applied to the face and face for 2 weeks each for 4 weeks. (24 ° C, relative humidity: 40%) after one week, two weeks, and four weeks after application and before two weeks (six weeks after completion of application) Skin moisture was measured and the results are shown in Table 3 below. The test result is a percentage of the increment of the measured value after a certain period of treatment based on the coneometer value measured just before the start of the test.

Test substance Moisture growth rate (%) 1 week Two weeks 4 weeks 6 weeks Example 36 40 43 34 Comparative Example 1 30 34 34 15 Comparative Example 2 28 30 30 13

Connio meter is a skin moisture analyzer that measures the amount of water present in the skin by measuring the electrical conductivity of the skin. As shown in Table 3, in the group containing the naturally fermented extract of the ginseng fruit according to the present invention, Comparative Examples 1 and 2 containing the ginseng fruit extract or ginseng root extract extracted by the general method were applied Increased skin moisture compared to one group. In addition, even after stopping the application of the nutritional cream of the examples, the skin moisture was measured to be similar to the one week after application, and skin moisture was maintained for a certain period of time without applying the example.

Claims (9)

A natural fermented extract of ginseng fruit as an active ingredient,
The naturally fermented extract of the ginseng fruit is obtained by mixing and fermenting ginseng fruit and one or more sugar components selected from the group consisting of sucrose, xylitol, oligosaccharide, erythritol, glucose and fructose,
Wherein the sugar component is mixed in an amount of 1 to 10% by weight based on the total weight of the ginseng fruit. The composition of claim 1 which is formulated into a transdermal dosage form selected from the group consisting of softening lotion, nutritional lotion, nutritional lotion, massage cream, nutritional cream, pack, gel, lotion, ointment, gel, cream, patch, ≪ / RTI > The skin cosmetic composition according to claim 1, wherein the composition is for skin whitening. The skin cosmetic composition according to claim 1, wherein the composition is for skin moisturizing. delete delete delete delete delete