KR101787983B1 - Frangnance cosmetic composition with antiseptic effect containing natural fragrances - Google Patents

Abstract

The present invention relates to a cosmetic composition having a preservative effect by containing a natural perfume, and more particularly, to a cosmetic composition having a preservative effect by containing a natural perfume, Lavender oil, and the like, and to a cosmetic composition using the preservative effect of natural perfumes.

Description

[0001] The present invention relates to a fragrance composition containing a natural fragrance and having an antiseptic effect containing natural fragrances,

The present invention relates to a cosmetic composition having a preservative effect by containing a natural perfume, and more particularly, to a cosmetic composition having a preservative effect by containing a natural perfume, Lavender oil, and the like, and to a cosmetic composition using the preservative effect of natural perfumes.

The role of preservatives in cosmetics is very important. In order to use our cosmetics, we open the lid and use it in the hands. In this case, cosmetics are contaminated by polluted substances in the air or contaminated microorganisms in our hands. Such contaminated cosmetic products are easily deteriorated and can no longer be used if the preservative treatment is not performed properly.

In recent years, many cosmetics have been developed using special containers to prevent contamination due to air or hand contact. Since cosmetics usually contain a certain amount of water, they are stored at a high temperature for a long time or at a high humidity There is a high possibility of alteration. For this reason cosmetics should be formulated with preservatives.

Preservatives used in cosmetics are mainly divided into synthetic preservatives and natural preservatives. Synthetic preservatives have been developed in a wide variety of terms, collectively referring to preservatives made by chemical synthesis. These synthetic preservatives are inexpensive and can be mass produced, but their use is very limited due to toxicity, skin irritation, and irritating odor. Among these synthetic preservatives, benzoic acid ester (paraben) preservatives are low in toxicity, irritation and odor compared to other preservatives, are widely available for microorganisms, are low in usage and persistent, It is mainly used as a preservative for cosmetics because it is difficult to penetrate into the skin. However, it has been reported that parabens can accumulate in the body as a pseudo-hormone component to disturb the female hormone system, thereby increasing the risk of breast cancer, inhibiting estrogen production, weakening liver function and causing depression. Is a trend to stop.

A natural preservative is a term derived from an animal or a plant and refers to a substance having an antimicrobial and antiseptic effect. The natural preservatives presently on the market are not very strong in buoyancy, so they should be added to cosmetics at a high concentration of 2% or more, and their use is limited because they are expensive and can cause discoloration when used at high concentrations. So far, no natural preservatives have been developed that exhibit a preservative effect comparable to synthetic preservatives.

Thus, the present inventors have conducted studies to improve the low repelling force of natural preservatives while solving the harmfulness of synthetic preservatives. In the present invention, as a result of research for producing a cosmetic composition having a preservative effect using only natural fragrances, natural perfumes such as cinnamon bark oil, cinnamon leaf oil, marzolam oil, rose oil, sandalwood oil, geranium oil and lavender oil The present inventors have completed the present invention.

Accordingly, it is an object of the present invention to provide a cosmetic composition using the preservative effect of natural fragrances without using a synthetic preservative.

In order to achieve the above object, the present invention relates to a composition comprising 20 to 50% by weight of cinnamon bark oil, 10 to 20% by weight of Cinnamon leaf oil, and 10 to 20% by weight of Marjoram oil ) 10 to 30% by weight as an active ingredient.

The present invention relates to a perfume composition containing cinnamon bark oil, cinnamon leaf oil, marzoam oil, rose oil, petroleum oil, geranium oil and lavender oil. By applying the perfume composition to cosmetics, .

The composition of the present invention provides a perfume composition containing Cinnamon bark oil, Cinnamon leaf oil and Marjoram oil as an active ingredient.

The perfume composition may further contain at least one selected from the group consisting of Rose oil, Sandalwood oil, Geranium oil and Lavender oil.

The perfume composition provided by the present invention has excellent antibacterial and repellent properties and can reduce adverse effects due to use of the synthetic preservative.

The cinnamon bark oil used in the present invention is a liquid having a yellow fluidity obtained by peeling the cinnamon tree and drying it and then distilling the water vapor, and has effects of detoxification, antibacterial, antiseptic, sterilization, promotion of digestion and promotion of blood circulation.

The cinnamon leaf oil used in the present invention is a dark yellow liquid obtained by steam distillation of the branches and leaves of cinnamon tree, and has an effect of preserving, sterilizing, antibacterial, sedative, promoting metabolism activity.

Marjoram oil used in the present invention is a pale yellow oil obtained by steam distillation after drying fresh leaves, and has antibacterial, antiseptic, antiviral, anticonvulsant and antioxidative effects.

The rose oil used in the present invention is a yellow liquid obtained by steam distillation of natural rose flowers, and is effective for preservation, antibacterial, relaxation of nervous tension, soothing effect, relieving depression.

The sandalwood oil used in the present invention is a pale yellow viscous liquid which is obtained by cutting sandalwood and cutting branches and leaves and then cutting and drying the wood finely. The oil is antibacterial, antibacterial, antidepressant, aphrodisiac, It is a natural fragrance.

The geranium oil used in the present invention is an oil obtained by steam distillation of geranium leaves and is a slightly brownish yellow liquid. This geranium oil has anti-depressive, anti-inflammatory, antiseptic, astringent, deodorizing and digestive effect.

Lavender oil used in the present invention is obtained by steam distillation of whole flower. This oil has a light yellow color, and it has effects of antidepressant, antibacterial, antiseptic, sterilization as well as detoxification, anticonvulsant, burn treatment.

The composition according to the present invention contains 20 to 50% by weight of cinnamon bark oil, 10 to 20% by weight of cinnamon leaf oil, 10 to 30% by weight of marjoram oil, 5 to 10% by weight of rose oil, 10 to 20% by weight of geranium oil, 10 to 20% by weight of geranium oil and 10 to 20% by weight of lavender oil. When the content of the oil is out of the above range with respect to the total weight of the composition, anticipatory preservative effect can not be obtained, The degree of preference drops significantly, which lowers the value of the product.

The perfume composition according to the present invention may be formulated into cosmetic compositions for external application to the skin such as perfumes and cosmetics, and may be appropriately selected and blended in order to achieve the desired effects according to the conventional techniques in the art, May be contained in an amount of 0.1 to 1.0% by weight based on the total weight of the cosmetic composition.

The external preparation for skin is not limited in its formulation and may be formulated in any formulation known in the art. Examples of formulations include packs, ointments, lotions, soluble powders, suspensions, emulsions, creams, gels, sprays, papermaking, warnings, patches or water pills.

Hereinafter, the present invention will be described in more detail with reference to examples and test examples, but the present invention is not limited to these examples.

[Example 1] A perfume composition having a preservative effect

As examples of the perfume composition according to the present invention, fragrances were prepared according to the composition shown in Table 1 below.

Antiseptic fragrance composition Component name (content;% by weight) Example 1 Example 2 Example 3 Example 4 Example 5 Example 6 Cinnamon Bark Oil 50 40 40 40 40 20 Cinnamon leaf oil 20 20 20 20 20 20 Marzoam oil 30 30 30 20 20 15 Rose oil 10 5 Sandalwood oil 10 5 Geranium oil 20 15 Lavender Oil 20 20 total 100 100 100 100 100 100

[Test Example 1] Evaluation of antibacterial activity of perfume composition

In order to confirm the antibacterial activity of the perfume composition according to the present invention, antibacterial experiments were conducted for Examples 1 to 6. Specific experimental methods are as follows.

Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa strains used in the experiment were obtained from Tryptic Soy Broth, Candida albicans and Aspergillus niger strains were cultured in Sabouraud Dextrose broth. The culture was added to each medium at a ratio of 1/100 (Candida albicans 1/10 diluted diluted solution was used as a test solution. Aspergillus niger, a spore suspension prepared to have a concentration of 2 × 10 ⁸ cfu / ml was used as the test strain.

0.15 ml of the above-mentioned test solution was added to 15 ml of each medium, and well-mixed solution was used as a diluting solution.

In a 96-well 96-well plate, add 16 μl of each sample to the first line, and add 184 μl of the diluted solution. In the remaining wells, 100 μl of the dilution solution was added. 100 μl of the mixed solution of No. 1 line was mixed well and 100 μl of the mixture was added to the No. 2 line. After mixing well, 100 μl of the mixture was added to the No. 3 line and diluted 2-fold.

Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa were incubated in a 32 ° C thermostat with Candida albicans, Aspergillus niger (Aspergillus niger), Staphylococcus aureus niger) were incubated in a 25 ° C incubator.

After 48 hours, the microbial proliferation was checked by suspension and microscope to determine the minimum inhibitory concentration (MIC) value. The results are shown in Table 2 below.

Result of antibacterial activity of natural fragrance Material name Minimum inhibitory concentration (MIC), unit% Sedona Monas
Aruzinosa Staphylococcus aureus Escherichia coli Candida
Albikans Aspergillus niger Methyl
Paraben 0.2 to 0.25 0.15-0.2 0.2 0.1 0.1 Cinnamon bark
oil One <0.0625 <0.0625 <0.0625 <0.0625 Cinnamon leaf
oil 4 0.125 0.5 <0.0625 <0.0625 Marzoam oil > 8 0.5 0.5 0.125 0.5 Rose oil > 8 > 8 0.25 0.25 <0.0625 Sandalwood oil > 8 > 8 <0.0625 > 8 > 8 Geranium
oil > 8 > 8 0.125 <0.0625 <0.0625 lavender
oil > 8 <0.0625 0.125 <0.0625 0.25 Example 1 0.25 0.125 0.125 0.03125 0.03125 Example 2 0.2 0.125 0.0625 0.03125 0.03125 Example 3 0.25 0.125 0.125 0.03125 0.03125 Example 4 0.25 0.125 0.125 0.03125 0.03125 Example 5 0.25 0.125 0.125 0.125 0.03125 Example 6 0.25 0.125 0.125 0.03125 0.03125

As shown in the above Table 2, the antibacterial activity of the perfume compositions of Examples 1 to 6 was similar to that of methylparaben, a synthetic preservative commonly used in cosmetics.

[Test Example 2] Estimation of buoyant force in cosmetic composition

To confirm the preservative effect when the perfume compositions of Examples 1 to 6 were contained in the product, cosmetic compositions of Examples 7 to 30 and Comparative Examples 2 to 5 were prepared as shown in Tables 3 to 6 below, Respectively.

The skin-form cosmetic composition ingredient Example
7 Example 8 Example
9 Example
10 Example
11 Example
12 Comparative Example
2 Purified water to 100 to 100 to 100 to 100 to 100 to 100 to 100 Trehalose 3.0 3.0 3.0 3.0 3.0 3.0 3.0 Concentrated glycerin 3.0 3.0 3.0 3.0 3.0 3.0 3.0 Butylene glycol 2.0 2.0 2.0 2.0 2.0 2.0 2.0 Polyoxyethylene hardened castor oil 0.3 0.3 0.3 0.3 0.3 0.3 0.3 Phenyl trimecicone 0.15 0.15 0.15 0.15 0.15 0.15 0.15 Carboxyvinyl polymer 0.08 0.08 0.08 0.08 0.08 0.08 0.08 Triethanolamine 0.05 0.05 0.05 0.05 0.05 0.05 0.05 Sodium ethylenediaminetetraacetate 0.02 0.02 0.02 0.02 0.02 0.02 0.02 Triethanolamine 0.05 0.05 0.05 0.05 0.05 0.05 0.05 Perfume (Example 1) 0.1 - - - - - - Perfume (Example 2) - 0.1 - - - - - The perfume (Example 3) - - 0.1 - - - - Perfume (Example 4) - - - 0.1 - - - Perfume (Example 5) - - - - 0.1 - - Perfume (Example 6) - - - - - 0.1 - Methyl paraben - - - - - - 0.15 Propylparaben - - - - - - 0.02 Phenoxyethanol - - - - - - 0.2

Lotion-formulated cosmetic composition ingredient Example 13 Example
14 Example
15 Example
16 Example
17 Example
18 Comparative Example 3 Purified water to 100 to 100 to 100 to 100 to 100 to 100 to 100 Liquid paraffin 5.0 5.0 5.0 5.0 5.0 5.0 5.0 Tree (capryl, capric acid) glycerin 5.0 5.0 5.0 5.0 5.0 5.0 5.0 Cetyl octanoate 5.0 5.0 5.0 5.0 5.0 5.0 5.0 Concentrated glycerin 3.0 3.0 3.0 3.0 3.0 3.0 3.0 Polyglyceryl-3-methyl glucoside distearate 2.0 2.0 2.0 2.0 2.0 2.0 2.0 Cyclomethicone 2.0 2.0 2.0 2.0 2.0 2.0 2.0 Dimethicone 1.0 1.0 1.0 1.0 1.0 1.0 1.0 Stearic acid 0.8 0.8 0.8 0.8 0.8 0.8 0.8 Cetostearyl alcohol 0.7 0.7 0.7 0.7 0.7 0.7 0.7 Pro-type glycerin monostearate 0.6 0.6 0.6 0.6 0.6 0.6 0.6 Triethanolamine 0.2 0.2 0.2 0.2 0.2 0.2 0.2 Carboxyvinyl polymer 0.15 0.15 0.15 0.15 0.15 0.15 0.15 Sodium ethylenediaminetetraacetate 0.02 0.02 0.02 0.02 0.02 0.02 0.02 Perfume (Example 1) 0.1 - - - - - - Perfume (Example 2) - 0.1 - - - - - The perfume (Example 3) - - 0.1 - - - - Perfume (Example 4) - - - 0.1 - - - Perfume (Example 5) - - - - 0.1 - - Perfume (Example 6) - - - - - 0.1 - Methyl paraben - - - - - - 0.2 Propylparaben - - - - - - 0.1 Phenoxyethanol - - - - - - 0.3

Cream formulated cosmetic composition ingredient Example 19 Example 20 Example 21 Example 22 Example 23 Example 24 Comparative Example 4 Purified water to 100 to 100 to 100 to 100 to 100 to 100 to 100 Liquid paraffin 10.0 10.0 10.0 10.0 10.0 10.0 10.0 Concentrated glycerin 7.0 7.0 7.0 7.0 7.0 7.0 7.0 Tree (capryl, capric acid) glycerin 5.0 5.0 5.0 5.0 5.0 5.0 5.0 Cetyl octanoate 5.0 5.0 5.0 5.0 5.0 5.0 5.0 Cyclomethicone 5.0 5.0 5.0 5.0 5.0 5.0 5.0 Propylene glycol 5.0 5.0 5.0 5.0 5.0 5.0 5.0 vaseline 3.0 3.0 3.0 3.0 3.0 3.0 3.0 Stearic acid 2.0 2.0 2.0 2.0 2.0 2.0 2.0 Cetostearyl alcohol 2.0 2.0 2.0 2.0 2.0 2.0 2.0 Pro-type glycerin monostearate 2.0 2.0 2.0 2.0 2.0 2.0 2.0 Triethanolamine 0.2 0.2 0.2 0.2 0.2 0.2 0.2 Polyoxyethylene sorbitan monostearate 1.5 1.5 1.5 1.5 1.5 1.5 1.5 Dimethicone 1.0 1.0 1.0 1.0 1.0 1.0 1.0 Sesquioleic acid sorbitan 0.8 0.8 0.8 0.8 0.8 0.8 0.8 Sodium ethylenediaminetetraacetate 0.02 0.02 0.02 0.02 0.02 0.02 0.02 Perfume (Example 1) 0.2 - - - - - - Perfume (Example 2) - 0.2 - - - - - The perfume (Example 3) - - 0.2 - - - - Perfume (Example 4) - - - 0.2 - - - Perfume (Example 5) - - - - 0.2 - - Perfume (Example 6) - - - - - 0.2 - Methyl paraben - - - - - - 0.2 Propylparaben - - - - - - 0.1 Phenoxyethanol - - - - - - 0.4 Chlorphenazine - - - - - - 0.2

Packaged cosmetic composition ingredient Example 25 Example 26 Example 27 Example 28 Example 29 Example 30 Comparative Example 5 Purified water to 100 to 100 to 100 to 100 to 100 to 100 to 100 Cyclopentasiloxane 6.30 6.30 6.30 6.30 6.30 6.30 6.30 Butylene glycol 6.00 6.00 6.00 6.00 6.00 6.00 6.00 glycerin 2.10 2.10 2.10 2.10 2.10 2.10 2.10 Trehalose 2.00 2.00 2.00 2.00 2.00 2.00 2.00 Dimethicone / Vinyl Dimethicone Crosspolymer 0.10 0.10 0.10 0.10 0.10 0.10 0.10 Dimethicone 0.20 0.20 0.20 0.20 0.20 0.20 0.20 Disodium iodide 0.02 0.02 0.02 0.02 0.02 0.02 0.02 Ammonium acryloyldimethyltaurate / Vpicopolymer 0.50 0.50 0.50 0.50 0.50 0.50 0.50 Carbomer 0.20 0.20 0.20 0.20 0.20 0.20 0.20 Triethanolamine 0.40 0.40 0.40 0.40 0.40 0.40 0.40 Polysorbate 20 0.60 0.60 0.60 0.60 0.60 0.60 0.60 Methylparaben - - - - - - 0.2 Clofenine - - - - - - 0.3 Perfume (Example 1) 0.2 - - - - - - Perfume (Example 2) - 0.2 - - - - - The perfume (Example 3) - - 0.2 - - - - Perfume (Example 4) - - - 0.2 - - - Perfume (Example 5) - - - - 0.2 - - Perfume (Example 6) - - - - 0.2 -

Escherichia coli (ATCC 8739) and Staphlyococcus aureus (ATCC 6538) were added to 20 to 30 g of the cosmetic compositions of Examples 7 to 30 and Comparative Examples 2 to 5, , And Pseudomonas aeruginosa (ATCC 99027) were added and mixed at an initial concentration of 10 ⁶ cfu (colony forming unit) / g per sample. 1 g of each cosmetic was taken at intervals of 1 day, 7 days, 14 days, 21 days, and 28 days while culturing them in a thermostat at 30 to 32 ° C for 4 weeks. The measurement results are shown in Table 7 below.

In the case of fungi, a mixed culture solution of Penicillium citrinum (ATCC 9849) and Aspergillus niger (ATCC 16404) was added at an initial concentration of 10 ⁶ cfu / g per sample, The presence or absence and the presence or absence of mycelia and spore formation on the surface of the sample were observed at intervals of 7 days while culturing, and the results are shown in Table 7 below.

Preservation experiment result of cosmetic composition Cosmetics Bacteria (cfu / g) mold
* Initial number of bacteria Day 1 Day 7 Day 14 Day 21 Day 28 Example 7 1 x 10 ⁶ <1000 <100 <100 <100 <100 - Example 8 1 x 10 ⁶ 2000 <100 <100 <100 <100 - Example 9 1 x 10 ⁶ <1000 <1000 <100 <100 <100 - Example 10 1 x 10 ⁶ 3000 2000 1000 <100 <100 - Example 11 1 x 10 ⁶ 10000 5000 1000 <1000 <1000 - Example 12 1 x 10 ⁶ 5000 5000 1000 <1000 <1000 - Comparative Example 2 1 x 10 ⁶ 25000 5000 1000 <1000 <1000 + Example 13 1 x 10 ⁶ <1000 <100 <100 <100 <100 - Example 14 1 x 10 ⁶ 10000 1200 <100 <100 <100 - Example 15 1 x 10 ⁶ 20000 1200 <100 <100 <100 - Example 16 1 x 10 ⁶ 1500 <1000 <100 <100 <100 - Example 17 1 x 10 ⁶ <1000 <1000 <100 <100 <100 - Example 18 1 x 10 ⁶ 2000 <100 <100 <100 <100 - Comparative Example 3 1 x 10 ⁶ 31000 1200 <100 <100 <100 - Example 19 1 x 10 ⁶ <1000 <100 <100 <100 <100 - Example 20 1 x 10 ⁶ <100 <100 <100 <100 <100 - Example 21 1 x 10 ⁶ <100 <100 <100 <100 <100 - Example 22 1 x 10 ⁶ <1000 <100 <100 <100 <100 - Example 23 1 x 10 ⁶ <1000 <100 <100 <1000 <100 - Example 24 1 x 10 ⁶ <100 <100 <100 <100 <100 - Comparative Example 4 1 x 10 ⁶ <1000 <100 <100 <100 <100 - Example 25 1 x 10 ⁶ <100 <100 <100 <100 <100 - Example 26 1 x 10 ⁶ <100 <100 <100 <100 <100 - Example 27 1 x 10 ⁶ <100 <100 <100 <100 <100 - Example 28 1 x 10 ⁶ <1000 <100 <100 <100 <100 - Example 29 1 x 10 ⁶ <1000 <100 <100 <100 <100 - Example 30 1 x 10 ⁶ <1000 <100 <100 <100 <100 - Comparative Example 5 1 x 10 ⁶ <1000 <100 <100 <100 <100 -

* -: No spawning and mycelium spawning for 8 weeks and good

+: Molding on the wall or lid within 4 weeks

++: mending within 4 weeks and mold on part of the surface

+++: Mildew and mold on the entire surface within 4 weeks

As shown in Table 7, it was confirmed that the cosmetic composition containing Examples 1 to 6 having a preservative effect exhibited the same level of repelling power as the cosmetic composition using the synthetic preservative.

Claims (11)

delete delete delete delete delete delete delete A composition comprising 20 to 50% by weight of Cinnamon bark oil, 10 to 20% by weight of Cinnamon leaf oil and 10 to 30% by weight of Marjoram oil, based on the total weight of the composition mixture; 5 to 10% by weight of Rose oil, 5 to 10% by weight of Sandalwood oil, 10 to 20% by weight of Geranium oil and 10 to 20% by weight of Geranium oil, based on the total weight of the composition, Of at least one oil selected from the group consisting of Lavender oil, as an active ingredient,
The total weight of the mixture of cinnamon bark oil, cinnamon leaf oil and marjoram oil and at least one oil selected from the group consisting of rose oil, sandalwood oil, geranium oil and lavender oil, 45 to 100% by weight,
The composition has antibacterial activity against bacteria or fungi,
Wherein the bacterium is at least one selected from the group consisting of Staphylococcus aureus , Escherichia coli and Pseudomonas aeruginosa ,
Wherein the fungus is at least one selected from the group consisting of Candida albicans , Penicillium citrinum , and Aspergillus niger .
9. The method according to claim 8, wherein the cinnamon bark oil is obtained by stripping the cinnamon bark, drying it, and obtaining it by steam distillation, wherein the cinnamon leaf oil is obtained by steam distillation of branches and leaves of cinnamon tree, Wherein the oil is obtained by drying marjoram leaf and then steam distillation, wherein the rose oil is obtained by steam distillation of rose flower, the sandalwood oil is obtained by extracting a branch tree from which branches and leaves have been removed, Wherein the geranium oil is obtained by steam distillation of geranium leaves, and the lavender oil is obtained by steam distillation of lavender flowers.
9. A cosmetic composition comprising the composition of claim 8 or 9 in an amount of 0.1 to 1.0% by weight based on the total weight of the cosmetic composition.
11. The cosmetic composition according to claim 10, wherein the composition is formulated as a pack, ointment, lotion, soluble composition, suspension, emulsion, cream, gel, spray, papermaking,