KR101691534B1 - 류마티스 관절염 및 골다공증 치료용 ｉｌ-20 길항제의 용도 - Google Patents

류마티스 관절염 및 골다공증 치료용 ｉｌ-20 길항제의 용도 Download PDF

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Publication number
KR101691534B1
KR101691534B1 KR1020117009475A KR20117009475A KR101691534B1 KR 101691534 B1 KR101691534 B1 KR 101691534B1 KR 1020117009475 A KR1020117009475 A KR 1020117009475A KR 20117009475 A KR20117009475 A KR 20117009475A KR 101691534 B1 KR101691534 B1 KR 101691534B1
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South Korea
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antibody
composition
mab
osteoporosis
antibodies
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KR1020117009475A
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English (en)
Korean (ko)
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KR20110094272A (ko
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밍-시 창
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내셔날 쳉쿵 유니버시티
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Priority claimed from US12/246,715 external-priority patent/US7837994B2/en
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26—Androgens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/32—Fusion polypeptide fusions with soluble part of a cell surface receptor, "decoy receptors"

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Diabetes (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Pain & Pain Management (AREA)
  • Biochemistry (AREA)
  • Reproductive Health (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
KR1020117009475A 2008-10-07 2009-10-07 류마티스 관절염 및 골다공증 치료용 ｉｌ-20 길항제의 용도 Expired - Fee Related KR101691534B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US12/246,715 US7837994B2 (en) 2008-10-07 2008-10-07 Use of anti-IL-20 antibody for treating osteoporosis
US12/246,715 2008-10-07
US23866109P 2009-08-31 2009-08-31
US61/238,661 2009-08-31
PCT/US2009/059865 WO2010042634A1 (en) 2008-10-07 2009-10-07 Use of il-20 antagonists for treating rheumatoid arthritis and osteoporosis

Publications (2)

Publication Number Publication Date
KR20110094272A KR20110094272A (ko) 2011-08-23
KR101691534B1 true KR101691534B1 (ko) 2017-01-09

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KR1020117009475A Expired - Fee Related KR101691534B1 (ko) 2008-10-07 2009-10-07 류마티스 관절염 및 골다공증 치료용 ｉｌ-20 길항제의 용도

Country Status (7)

Country Link
EP (1) EP2340039B1 (enExample)
JP (2) JP5860699B2 (enExample)
KR (1) KR101691534B1 (enExample)
CN (1) CN102281898B (enExample)
CA (1) CA2739794A1 (enExample)
DK (1) DK2340039T3 (enExample)
WO (1) WO2010042634A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2796064A1 (en) * 2010-04-16 2011-10-20 National Cheng Kung University Treating disorders associated with il-20 receptor-mediated signaling pathway by blocking il-20 receptor activity
WO2014006230A1 (en) 2012-07-06 2014-01-09 Novo Nordisk A/S Il-20 epitopes and il-20 ligands
CA2878825A1 (en) * 2012-07-10 2014-01-16 The Uab Research Foundation Compositions and methods for modulation of il-20 family cytokine activity
US8603470B1 (en) * 2012-08-07 2013-12-10 National Cheng Kung University Use of IL-20 antagonists for treating liver diseases
US9376490B2 (en) * 2014-04-01 2016-06-28 National Cheng Kung University Treatment of inflammatory pain using IL-20 antagonists
CA2961597A1 (en) * 2014-11-24 2016-06-02 Inserm (Institut National De La Sante Et De La Recherche Medicale) Treatment of acute exacerbations of chronic obstructive pulmonary disease by antagonism of the il-20r.
US9982043B2 (en) 2016-06-03 2018-05-29 National Cheng Kung University Use of IL-20 antagonists for treating pancreatic cancer
KR101796025B1 (ko) 2017-04-25 2017-11-10 가톨릭대학교 산학협력단 사포그릴레이트, 프라바스타틴 및 tnf-억제제를 유효성분으로 포함하는 죽상동맥경화증 예방 또는 치료용 약학조성물

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060142550A1 (en) 2003-05-23 2006-06-29 Chi-Mei Medical Center Antibodies to interleukin-20 and method for inhibiting interleukin-20 induced cell proliferation

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BRPI9707379C8 (pt) * 1996-02-09 2017-12-12 Abbott Biotech Ltd composições farmacêuticas compreendendo anticorpo humano recombinante geneticamente engenheirado, e anticorpo humano recombinante geneticamente engenheirado.
US6649779B2 (en) * 1997-05-02 2003-11-18 Wyeth Estrenes
KR100574387B1 (ko) * 1997-11-26 2006-04-27 지모제넥틱스, 인코포레이티드 포유류 시토카인 유사 폴리펩티드-10
US20030148955A1 (en) * 1999-04-19 2003-08-07 Pluenneke John D. Soluble tumor necrosis factor receptor treatment of medical disorders
EP1244708B8 (en) * 1999-12-23 2007-03-07 ZymoGenetics, Inc. Method for treating inflammation
AU783473B2 (en) * 1999-12-23 2005-10-27 Zymogenetics Inc. Soluble interleukin-20 receptor
US6610286B2 (en) * 1999-12-23 2003-08-26 Zymogenetics, Inc. Method for treating inflammation using soluble receptors to interleukin-20
US7122632B2 (en) * 1999-12-23 2006-10-17 Zymogenetics, Inc. Soluble Interleukin-20 receptor
US20050143333A1 (en) * 2001-05-18 2005-06-30 Sirna Therapeutics, Inc. RNA interference mediated inhibition of interleukin and interleukin receptor gene expression using short interfering nucleic acid (SINA)
WO2003026568A2 (en) * 2001-09-21 2003-04-03 Merck & Co., Inc. Androstanes as androgen receptor modulators
EP1446114A4 (en) * 2001-11-08 2005-05-25 Merck & Co Inc COMPOSITIONS AND METHODS FOR TREATING OSTEOPOROSIS
CA2545867A1 (en) * 2003-11-21 2005-06-09 Zymogenetics, Inc. Anti-il-20 antibodies and binding partners and methods of using in inflammation
WO2007116818A1 (ja) * 2006-03-30 2007-10-18 Toray Industries, Inc. 樹状ポリエステル、その製造方法および熱可塑性樹脂組成物
JP5330829B2 (ja) * 2006-08-04 2013-10-30 憲弘 西本 関節リウマチ患者の治療予後予測方法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060142550A1 (en) 2003-05-23 2006-06-29 Chi-Mei Medical Center Antibodies to interleukin-20 and method for inhibiting interleukin-20 induced cell proliferation

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Bone, Vol. 35, No. 5, pp. 1200-1207 (2004.09.28.).

Also Published As

Publication number Publication date
KR20110094272A (ko) 2011-08-23
EP2340039B1 (en) 2015-11-25
EP2340039A4 (en) 2012-10-24
CN102281898B (zh) 2015-06-03
CA2739794A1 (en) 2010-04-15
AU2009302383B2 (en) 2016-05-12
JP5860699B2 (ja) 2016-02-16
EP2340039A1 (en) 2011-07-06
JP2012505227A (ja) 2012-03-01
DK2340039T3 (en) 2016-02-29
CN102281898A (zh) 2011-12-14
AU2009302383A1 (en) 2010-04-15
JP2016041730A (ja) 2016-03-31
WO2010042634A1 (en) 2010-04-15

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