KR101668421B1 - A cosmetic composition for wrinkle improvement containing hurb extracts - Google Patents

Abstract

The present invention relates to a cosmetic composition for improving wrinkles containing a herbal medicine extract. More particularly, the present invention relates to a cosmetic composition for improving wrinkles containing at least two kinds selected from extracts of herbal medicines consisting of oats, salted and dried.

Antioxidant, wrinkle, anti-aging, cosmetic, composition

Description

[0001] The present invention relates to a cosmetic composition for wrinkle improvement containing horn extract,

The present invention relates to a cosmetic composition for improving wrinkles containing a herbal medicine extract. More particularly, the present invention relates to a cosmetic composition for improving wrinkles containing at least two kinds selected from extracts of herbal medicines consisting of oats, salted and dried.

Cosmetics are deeply related to our daily lives and are used by many people. Before the development of human civilization, the purpose of makeup was to protect the body from nature, but with the development of science and civilization, the purpose of makeup is to make the body clean and beautiful, and also to delay the aging to make beautiful and pleasant life It changed. The functions of cosmetics are not only clean and aesthetic, but also free radicals (radicals) due to external factors such as moisture, pollutants and stress, ultraviolet rays, internal factors such as impaired immune cell function, , And to remove or suppress the cause of skin aging such as protein, nucleic acid, cell membrane lipid breakage by peroxide and the like. In addition, cosmetics having whitening, skin wrinkle improvement and inhibition, and ultraviolet shielding function are continuously being developed to meet consumers' desire for high-performance cosmetics. Among them, wrinkle improvement and restraining products are attracting much attention from consumers who want to keep younger.

Wrinkles are formed by repeated movement of muscles over a long period of time in a specific direction, which is affected by age, external environment, ultraviolet radiation, and the like. Damage of skin cells caused by these factors causes various aging phenomena. Since the formation and decomposition of collagen, elastin, and GAGs constituting the dermis matrix do not occur smoothly, the firmness of the matrix deteriorates and the skin elasticity is lowered and wrinkles are formed.

Presently, retinoids, adenosine, animal placenta-derived proteins, chlorella extract, and the like are known to improve wrinkles. The best known retinol is a substance that promotes collagen synthesis, but it is unstable. When applied to the skin, it has a limited amount of use due to safety problems such as irritation and seizure, and chlorella extract has little effect, It is known.

      On the other hand, skin is exposed to ultraviolet rays, and photochemical reactions that make active oxygen species continue to occur, and these reactive oxygen species lead to skin cell and tissue damage. They break down the antioxidant defense network consisting of antioxidant enzymes and non-enzymatic antioxidants, thereby biasing the oxidant / antioxidant balance towards the oxidized state. Therefore, in order to protect a healthy body, a system capable of efficiently protecting the generated active oxygen must be included in the prescription of cosmetics. In other words, it is necessary to construct an antioxidant defense system for the skin in which the oxidant / antioxidant balance is maintained.

To date, substances known to have antioxidant activity include ascorbic acid, dl-alpha-tocopherol, beta-carotene, and dibutylhydroxyltoluene (BHT). However, since these materials are used as a synthetic product, they may cause problems of skin safety when used for a long time or when used in large amounts. Therefore, it is urgently required to develop new antioxidative cosmetics that can be applied to skin safely and usefully.

A problem to be solved by the present invention is to provide an excellent cosmetic composition for improving wrinkles containing a herbal medicine extract. And particularly to a cosmetic composition having an excellent antioxidative effect.

The present invention provides a cosmetic composition for improving wrinkles containing at least two kinds selected from the extracts of herbal medicines consisting of oats, sachets and alfalfa.

The cosmetic composition containing at least two selected from the extracts of herbal medicines consisting of oats, sachets and alfalfa according to the present invention has an effect of promoting the improvement of skin wrinkles. The cosmetic composition containing the herbal medicines extract has an anti- ≪ / RTI >

The present invention provides a cosmetic composition for improving wrinkles containing at least two kinds selected from the extracts of herbal medicines consisting of oats, sachets and alfalfa.

The oak is a medicinal substance which fumigates under- fruited fruit of Prunusmume Sieb. EtZucc., And contains citric acid, malic acid, succinic acid, carbohydrate, It is known that it consists of triterpenoids, oleanolic acid, sitosterol and the like.

The above-mentioned Hashuo is a vineous Pleuropterusmultflorus with dicotyledonous spruce , and is mainly divided into two kinds of seaweed and white seaweed , and the seaweed grown in Korea is mainly white seaweed. The physiological activity of the Sasa is known to be due to anthraquinone contained in the sewage, but the Sasa contains various plant sterols and various glycoside compounds.

The baekchul means that removal of the rhizomes or jupi of a kind of medicinal plants, sapju (Atractylodesjapanica Koidzumi) or sugar baekchul (Atractylodesovata Koidzumi).

The extraction solvent may be a polar solvent selected from water (purified water), lower alcohols having 1 to 4 carbon atoms, or a mixed solvent thereof, preferably ethanol, followed by hot water extraction.

The amount of the extraction solvent is 2 to 10 times the dry weight of the herbal medicine. The extraction method may be an extraction method such as hot water extraction, reflux cooling extraction, ultrasonic extraction, etc., and may be extracted once to five times, preferably as an extraction method of hot water extraction.

The immersion temperature is most preferably 30 to 70 ° C, more preferably 40 to 60 ° C, and most preferably 50 ° C to prevent decay, discoloration, and detachment. The immersion time is 5 to 20 hours , Preferably 10 hours.

After extracting the herbal medicine extract, the solid content is removed by using a filter paper or the like, the suspension may be centrifuged, and the supernatant may be subjected to filtration under reduced pressure. The filtered extract is dried in a vacuum rotary condenser at 20 to 100 ° C Can be concentrated under reduced pressure at 50 to 70 DEG C. The herbal medicine extract according to the present invention has excellent wrinkle-reducing effect and shows an application for improvement of skin condition.

In the composition of the present invention, the herbal medicine extract may be contained in an amount of 0.001 to 20% by weight based on the total weight of the composition. If the amount is less than 0.001% by weight, the effect is insignificant, and if it is more than 20% by weight, the stability of the formulation may be affected.

The cosmetics prepared from the cosmetic composition containing the herbal medicine extract of the present invention as an active ingredient can be prepared in the form of a general emulsified formulation and a solubilized formulation. Cosmetics of emulsified form include nutrition lotion, cream, essence, etc., and cosmetics of solubilized form have softening longevity. In addition to cosmetics containing the herbal medicinal extract of the present invention, it can be prepared in the form of adjuvant which can be applied topically or systemically, which is conventionally used in the field of dermatology by containing a dermatologically acceptable medium or base.

Suitable cosmetic formulations include, for example, solutions, gels, solid or kneaded anhydrous products, emulsions obtained by dispersing the oil phase in water, suspensions, microemulsions, microcapsules, microgranules or ionic (liposomes) In the form of a fodder dispersant, in the form of a cream, a skin, lotions, powders, ointments, sprays or conceal sticks. It can also be prepared in the form of a foam or an aerosol composition further containing a compressed propellant.

The cosmetic composition of the present invention may further contain, in addition to the herbal medicine extract, a lipid, an organic solvent, a solubilizing agent, a thickening agent and a gelling agent, a softening agent, an antioxidant, a suspending agent, a stabilizer, a foaming agent, , Ionic or nonionic emulsifiers, fillers, sequestering and chelating agents, preservatives, vitamins, barrier agents, wetting agents, essential oils, dyes, pigments, hydrophilic or lipophilic active agents, lipid vesicles or cosmetics And may contain adjuvants commonly used in the cosmetics or dermatological fields, such as any other ingredient. And, the above ingredients can be introduced in amounts commonly used in the field of dermatology.

Examples of products to which the cosmetic composition of the present invention can be added include cosmetics such as astringent lotion, softening longevity lotion, nutrition lotion, various creams, essences, packs, foundation and the like, cleansing, cleanser, soap, .

As a specific formulation of the cosmetic composition of the present invention, there may be mentioned a skin lotion, a skin softener, a skin toner, an astringent, a lotion, a milk lotion, a moisturizing lotion, a nutrition lotion, a massage cream, And includes formulations such as soap, shampoo, cleansing foam, cleansing lotion, cleansing cream, body lotion, body cleanser, milky lotion, press powder, loose powder, eye shadow and the like.

Hereinafter, preferred embodiments and experimental examples are provided to facilitate understanding of the present invention. However, the following examples and experimental examples are provided only for the purpose of easier understanding of the present invention, and the present invention is not limited by the examples.

Hereinafter, the present invention will be described in more detail with reference to the following Reference Examples, Examples and Comparative Examples. However, the following Reference Examples, Examples and Comparative Examples are intended to illustrate the present invention, but the scope of the present invention is not limited thereto.

[Referential Example 1] Preparation of oat extract

70% ethanol in an amount of four times the weight (Kg) was added to 500 g of oats, and the resulting mixture was heated at 80 DEG C for 2 hours to extract an effective ingredient. This was allowed to stand at room temperature for one day to precipitate impurities. The filtrate was filtered twice using a filter paper, and the filtrate was completely evaporated by using a reduced pressure evaporator and concentrated.

[Referential Example 2] Preparation of Sucrose Extract

70% ethanol in an amount of four times by weight (Kg) was added to 500 g of Sasao, and the mixture was heated at 80 DEG C for 2 hours to extract the active ingredient. This was allowed to stand at room temperature for one day to precipitate impurities. The filtrate was filtered twice using a filter paper, and the filtrate was completely evaporated by using a reduced pressure evaporator and concentrated.

[Referential Example 3] Preparation of dried extract

70% ethanol in an amount of 4 times the weight (Kg) was added to 500 g of the extract, and the extract was heated at 80 DEG C for 2 hours to extract an active ingredient. This was allowed to stand at room temperature for one day to precipitate impurities. The filtrate was filtered twice using a filter paper, and the filtrate was completely evaporated by using a reduced pressure evaporator and concentrated.

Cosmetic preparations containing two or more kinds of herbal medicine extracts of Reference Examples 1 to 3 were prepared, and for comparison, cosmetic compositions containing herbal extract alone were prepared at the composition ratios shown in Table 1 below.

division Content (% by weight) ingredient Example 1 Example 2 Example 3 Example 4 Comparative Example 1 Comparative Example 2 Comparative Example 3 Oat extract
(Reference Example 1) 1.0 1.0 - 1.0 2.0 - - Sashou extract
(Reference Example 2) 1.0 - 1.0 0.05 - 2.0 - Dried extract
(Reference Example 3) - 1.0 1.0 0.05 - - 2.0 Butylene glycol 2.0 2.0 2.0 2.0 2.0 2.0 2.0 Propylene glycol 6.0 6.0 6.0 6.0 6.0 6.0 6.0 Carboxyvinyl polymer 0.5 0.5 0.5 0.5 0.5 0.5 0.5 Wax 2.0 2.0 2.0 2.0 2.0 2.0 2.0 vaseline 7.0 7.0 7.0 7.0 7.0 7.0 7.0 Polysorbate 60 2.0 2.0 2.0 2.0 2.0 2.0 2.0 Sorbitan sesquioleate 2.5 2.5 2.5 2.5 2.5 2.5 2.5 Squalane 3.0 3.0 3.0 3.0 3.0 3.0 3.0 Liquid paraffin 10.0 10.0 10.0 10.0 10.0 10.0 10.0 Triethanolamine 0.5 0.5 0.5 0.5 0.5 0.5 0.5 Tocopheryl acetate 0.1 0.1 0.1 0.1 0.1 0.1 0.1 Spices, preservatives a very small amount a very small amount a very small amount a very small amount a very small amount a very small amount a very small amount Purified water Balance Balance Balance Balance Balance Balance Balance Sum 100 100 100 100 100 100 100

[Experimental Example 1] Wrinkle improvement clinical effect

The clinical effect of improving the skin wrinkle on the cosmetic containing the herbal medicine extract of the present invention was measured. Twenty women aged 40 or older (mean age 44.5 years) were divided into two groups (A and B). The subjects were divided into groups A and B, 2 times / day, 0.2 g / times), the degree of improvement (? W) of the skin wrinkles was measured by classifying the objective evaluation of the expert according to the following seven grades. The results are shown in Table 2 below.

Very badly aggravated -3 worse -2 Slightly worse -One No change 0 Slight improvement One Improving 2 Very much improved 3

* Wrinkle Evaluation Criteria

Objective evaluation of expert division Average wrinkle improvement ingredient Example 1 Example 2 Example 3 Example 4 Comparative Example 1 Comparative Example 2 Comparative Example 3 ? W (T12-T0) 2.2 2.4 2.0 2.8 1.0 1.2 1.0

After 12 weeks from the test results, it was found that the degree of improvement of the average wrinkles was significantly higher in Examples 1 to 4 containing two or more herbal extracts in the objective evaluation of the skilled artisans, compared with Comparative Examples 1 to 3 containing herbal extracts alone Respectively.

[Experimental Example 2] Skin elasticity improvement effect

The elasticity of skin elasticity was measured for a cosmetic composition containing the herbal medicine extract of the present invention. The elasticity of the skin was measured using a skin elasticity meter (Cutometer MPA 580, CK Electronic GmbH) Respectively.

That is, in Table 3, the degree of skin adsorption indicates the degree of adsorption, which indicates the penetration depth of the skin into the aperture in the instrument of the kittometer, and the smaller the value, the better. The degree of improvement in the elasticity of the skin after applying the above-mentioned Examples and Comparative Examples was confirmed at 100% before application.

Skin elasticity effect division Skin adsorption (%) ingredient Example 1 Example 2 Example 3 Example 4 Comparative Example 1 Comparative Example 2 Comparative Example 3 ? W (T12-T0) 67.3 66.2 66.8 59.1 96.5 94.6 94.8

As a result, it can be seen from the results shown in Table 3 that the cosmetic containing two or more kinds of herbal medicine extracts according to the present invention significantly enhances the skin wrinkle improving effect and the elasticity effect compared to the cosmetic containing the herbal medicine extract alone It can be seen that it exerts an excellent effect of preventing skin aging.

      Based on the results of the above Experimental Examples, a cosmetic composition containing the herbal medicine extract of the present invention is prepared and presented. However, the composition of the present invention is not intended to be limited to the following formulation examples.

[Formulation Example 1] Flexible lotion

     Formulation examples of a soft lotion containing a herbal medicine extract were prepared according to the composition shown in Table 4 below.

Raw material Content (% by weight) Herbal medicine extract 1.00 1,3-butylene glycol 1.00 Disodium iodide 0.05 Allantoin 0.10 Dipotassium glycyrrhizate 0.05 Citric acid 0.01 Sodium citrate 0.02 Glycereth-26 1.00 Arbutin 2.00 Hydrogenated castor oil 1.00 ethanol 30.00 Preservative a very small amount coloring agent a very small amount Flavoring agent a very small amount Purified water Balance

[Formulation Example 2] Nourishing cream

Formulation examples of nutritional creams containing herbal extracts were prepared according to the composition shown in Table 5 below.

Raw material Content (% by weight) Herbal medicine extract 2.0 1,3-butylene glycol 7.0 glycerin 1.0 D-Panthenol 0.1 Plant extract 3.2 Magnesium aluminum silicate 0.3 PEG-40 stearate 1.2 Stearic acid 2.0 Polysorbate 60 1.5 Chin type glyceryl stearate 2.0 Sorbitan sesquioleate 1.5 Cetearyl alcohol 3.0 Mineral oil 4.0 Squalane 3.8 Carlyric / capric triglyceride 2.8 vegetable oil 1.8 Dimethicone 0.4 Dipotassium glycyrrhizate a very small amount Allantoin a very small amount Sodium hyaruronate a very small amount Tocopheryl acetate Suitable amount Triethanolamine Suitable amount Preservative Suitable amount Flavoring agent Suitable amount Purified water Balance

Claims (3)

A cosmetic composition for improving wrinkles containing a mixture of an oat extract, The cosmetic composition for wrinkle improvement according to claim 1, wherein the weight ratio of the oat extract: Sasao extract: Baekjang extract is 2: 1: 1. [Claim 3] The composition according to claim 1, wherein the content of the oats extract is 0.002 to 20% by weight based on the total weight of the composition, The content of the extract of Sasa extract is 0.001 to 10% by weight based on the total weight of the composition, Wherein the content of the dried extract is 0.001 to 10% by weight based on the total weight of the composition. delete