KR101612563B1 - 도파민 수용체 리간드를 함유하는 약학적 조성물 및 도파민 수용체 리간드를 사용한 치료 방법 - Google Patents

도파민 수용체 리간드를 함유하는 약학적 조성물 및 도파민 수용체 리간드를 사용한 치료 방법 Download PDF

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KR101612563B1
KR101612563B1 KR1020107004638A KR20107004638A KR101612563B1 KR 101612563 B1 KR101612563 B1 KR 101612563B1 KR 1020107004638 A KR1020107004638 A KR 1020107004638A KR 20107004638 A KR20107004638 A KR 20107004638A KR 101612563 B1 KR101612563 B1 KR 101612563B1
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escitalopram
treatment
cariprazine hydrochloride
depression
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KR20100059830A (ko
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니카 애드함
게리 사모리스키
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리히터 게데온 닐트.
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • AHUMAN NECESSITIES
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    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
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    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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  • Animal Behavior & Ethology (AREA)
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  • General Health & Medical Sciences (AREA)
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  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Addiction (AREA)
  • Anesthesiology (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Otolaryngology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020107004638A 2007-08-03 2008-08-04 도파민 수용체 리간드를 함유하는 약학적 조성물 및 도파민 수용체 리간드를 사용한 치료 방법 Active KR101612563B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US95369407P 2007-08-03 2007-08-03
US60/953,694 2007-08-03

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KR20100059830A KR20100059830A (ko) 2010-06-04
KR101612563B1 true KR101612563B1 (ko) 2016-04-14

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KR1020107004638A Active KR101612563B1 (ko) 2007-08-03 2008-08-04 도파민 수용체 리간드를 함유하는 약학적 조성물 및 도파민 수용체 리간드를 사용한 치료 방법

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US (3) US20090036468A1 (https=)
EP (1) EP2185155B1 (https=)
JP (1) JP5460594B2 (https=)
KR (1) KR101612563B1 (https=)
CN (1) CN101815519B (https=)
AU (1) AU2008283989B2 (https=)
CA (1) CA2695519A1 (https=)
CY (1) CY1119828T1 (https=)
DK (1) DK2185155T3 (https=)
EA (1) EA018064B1 (https=)
ES (1) ES2653852T3 (https=)
HR (1) HRP20171908T1 (https=)
HU (1) HUE036004T2 (https=)
LT (1) LT2185155T (https=)
MY (1) MY157192A (https=)
NO (1) NO2185155T3 (https=)
PL (1) PL2185155T3 (https=)
PT (1) PT2185155T (https=)
SI (1) SI2185155T1 (https=)
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Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2317852T3 (pl) 2008-07-16 2015-05-29 Richter Gedeon Nyrt Preparaty farmaceutyczne zawierające ligandy receptora dopaminy
US20110117214A1 (en) * 2009-11-16 2011-05-19 Auspex Pharmaceuticals, Inc. Cyclohexyl urea modulators of d2 receptors and/or d3 receptors
US8691836B2 (en) * 2010-06-18 2014-04-08 Altos Therapeutics, LLC D2 antagonists, methods of synthesis and methods of use
US8912197B2 (en) 2012-08-20 2014-12-16 Forest Laboratories Holdings Ltd. Crystalline form of carbamoyl-cyclohexane derivatives
US11274087B2 (en) 2016-07-08 2022-03-15 Richter Gedeon Nyrt. Industrial process for the preparation of cariprazine
HUP1700253A1 (hu) * 2017-06-13 2019-01-28 Richter Gedeon Nyrt Szilárd orális gyógyszerkészítmények
GB2571696B (en) 2017-10-09 2020-05-27 Compass Pathways Ltd Large scale method for the preparation of Psilocybin and formulations of Psilocybin so produced
US12459965B2 (en) 2017-10-09 2025-11-04 Compass Pathfinder Limited Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use
US11547707B2 (en) 2019-04-10 2023-01-10 Richter Gedeon Nyrt. Carbamoyl cyclohexane derivatives for treating autism spectrum disorder
HU231500B1 (hu) * 2019-04-10 2024-04-28 Richter Gedeon Nyrt Karbamoil-ciklohexán származékok autizmus spektrum betegség kezelésére
KR20220009954A (ko) 2019-04-17 2022-01-25 컴퍼스 패쓰파인더 리미티드 신경인지 장애, 만성 통증을 치료하고 염증을 감소시키는 방법
MX2024005256A (es) * 2021-10-28 2024-09-06 Abbvie Inc Tratamiento del trastorno depresivo mayor.
KR20240122455A (ko) * 2021-12-13 2024-08-12 컴퍼스 패쓰파인더 리미티드 치료-저항성 우울증의 치료에서 사용하기 위한 실로사이빈 및 보조적 세로토닌 재흡수 저해제
IL315074A (en) 2022-03-17 2024-10-01 Mapi Pharma Ltd Storage systems containing cryprazine or its salts

Family Cites Families (14)

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Publication number Priority date Publication date Assignee Title
GB8814057D0 (en) * 1988-06-14 1988-07-20 Lundbeck & Co As H New enantiomers & their isolation
ZA977967B (en) * 1996-09-23 1999-03-04 Lilly Co Eli Combination therapy for treatment of psychoses
US6960577B2 (en) * 1998-05-22 2005-11-01 Eli Lilly And Company Combination therapy for treatment of refractory depression
US6556540B1 (en) * 1998-05-29 2003-04-29 Paradyne Corporation System and method for non-intrusive measurement of service quality in a communications network
TR200401456T1 (tr) * 1999-10-25 2005-04-21 H. Lundbeck A/S Sitalopram hazırlanması için yöntem.
UA77650C2 (en) * 1999-12-06 2007-01-15 Lundbeck & Co As H Use of serotonin reuptake inhibitor in combination with deramcyclane
EA200301195A1 (ru) * 2001-05-01 2004-04-29 Х. Лундбекк А/С Применение энантиомерно чистого эсциталопрама
US7030122B2 (en) * 2002-04-12 2006-04-18 Sepracor Inc. 1,4-disubstituted piperazine ligands for neurotransmitter receptors
WO2004000326A1 (en) * 2002-06-20 2003-12-31 H. Lundbeck A/S Combination therapy wherein a serotonin reuptake inhibitor is used
HU227534B1 (en) * 2003-08-04 2011-08-29 Richter Gedeon Nyrt (thio)carbamoyl-cyclohexane derivatives, process for producing them and pharmaceutical compositions containing them
US20070042014A1 (en) * 2003-09-04 2007-02-22 H. Lundbeck A/S Combination of a serotonin reuptake inhibitor and loxapine
HUP0500170A3 (en) * 2005-02-03 2007-11-28 Richter Gedeon Nyrt Piperazine derivatives, process for producing them and pharmaceutical compositions containing them
TW200812993A (en) * 2006-05-02 2008-03-16 Lundbeck & Co As H New uses of escitalopram
HU230748B1 (hu) * 2007-05-11 2018-02-28 Richter Gedeon Nyrt Új piperazin só és előállítási eljárása

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EA201000280A1 (ru) 2010-08-30
LT2185155T (lt) 2017-12-11
HK1144784A1 (en) 2011-03-11
WO2009020897A1 (en) 2009-02-12
PT2185155T (pt) 2018-01-04
CA2695519A1 (en) 2009-02-12
EP2185155A1 (en) 2010-05-19
HUE036004T2 (hu) 2018-06-28
US20120028991A1 (en) 2012-02-02
JP2010535790A (ja) 2010-11-25
SI2185155T1 (en) 2018-02-28
CY1119828T1 (el) 2018-06-27
MY157192A (en) 2016-05-13
US20090036468A1 (en) 2009-02-05
KR20100059830A (ko) 2010-06-04
PL2185155T3 (pl) 2018-03-30
AU2008283989B2 (en) 2013-12-05
EA018064B1 (ru) 2013-05-30
CN101815519B (zh) 2013-08-21
AU2008283989A1 (en) 2009-02-12
HRP20171908T1 (hr) 2018-01-26
EP2185155A4 (en) 2012-04-25
NO2185155T3 (https=) 2018-03-03
US20110015208A1 (en) 2011-01-20
EP2185155B1 (en) 2017-10-04
JP5460594B2 (ja) 2014-04-02
ES2653852T3 (es) 2018-02-09
CN101815519A (zh) 2010-08-25
DK2185155T3 (en) 2018-01-02

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