KR101580907B1 - 알파-1-안티트립신 및 아포지단백질 ａ-ｉ의 정제 방법 - Google Patents

알파-1-안티트립신 및 아포지단백질 ａ-ｉ의 정제 방법 Download PDF

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KR101580907B1
KR101580907B1 KR1020107005824A KR20107005824A KR101580907B1 KR 101580907 B1 KR101580907 B1 KR 101580907B1 KR 1020107005824 A KR1020107005824 A KR 1020107005824A KR 20107005824 A KR20107005824 A KR 20107005824A KR 101580907 B1 KR101580907 B1 KR 101580907B1
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South Korea
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aat
apoa
fraction
purification
delete delete
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KR1020107005824A
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Korean (ko)
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KR20100074134A (ko
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나단 브링크만
더글라스 비글러
라인할트 볼리
브레니 푀르츠
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체에스엘 베링 게엠베하
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Publication of KR20100074134A publication Critical patent/KR20100074134A/ko
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/775—Apolipopeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8121—Serpins
    • C07K14/8125—Alpha-1-antitrypsin

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020107005824A 2007-08-17 2008-08-15 알파-1-안티트립신 및 아포지단백질 ａ-ｉ의 정제 방법 KR101580907B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US93552707P 2007-08-17 2007-08-17
US60/935,527 2007-08-17

Publications (2)

Publication Number Publication Date
KR20100074134A KR20100074134A (ko) 2010-07-01
KR101580907B1 true KR101580907B1 (ko) 2015-12-29

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KR1020107005824A KR101580907B1 (ko) 2007-08-17 2008-08-15 알파-1-안티트립신 및 아포지단백질 ａ-ｉ의 정제 방법

Country Status (13)

Country Link
US (3) US8436152B2 (xx)
EP (3) EP2520583A1 (xx)
JP (1) JP5600061B2 (xx)
KR (1) KR101580907B1 (xx)
CN (3) CN103396479A (xx)
AU (1) AU2008289543B2 (xx)
CA (1) CA2694854C (xx)
DK (1) DK2183268T3 (xx)
ES (1) ES2397280T3 (xx)
NZ (3) NZ582170A (xx)
PL (1) PL2183268T3 (xx)
SG (1) SG183743A1 (xx)
WO (1) WO2009025754A2 (xx)

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CN102127165B (zh) * 2010-01-15 2013-09-04 上海莱士血液制品股份有限公司 一种从血浆组分四沉淀中制备高纯ApoA-I的生产工艺
CN103118683B (zh) 2010-06-30 2015-08-19 杰特有限公司 重建高密度脂蛋白制剂及其生产方法
SI2767546T1 (sl) 2011-02-07 2019-03-29 Cerenis Therapeutics Holding Sa Lipoproteinski kompleksi in izdelava ter uporaba le-teh
CN102731642B (zh) * 2011-04-14 2014-01-29 上海莱士血液制品股份有限公司 从人血浆组分四沉淀制备高纯Apoa-I的生产工艺
US9353165B2 (en) * 2012-07-25 2016-05-31 Grifols, S.A. Purification of cell culture derived alpha1 protease inhibitor
CN102766205B (zh) * 2012-07-25 2013-10-02 深圳市宝凯仑科技有限公司 一种载脂蛋白b的快速纯化方法
US9534029B2 (en) 2012-10-03 2017-01-03 Csl Behring Ag Method of purifying proteins
CN104968676A (zh) * 2012-10-03 2015-10-07 美国杰特贝林生物制品有限公司 一种纯化蛋白质的方法
US9125943B2 (en) 2012-11-02 2015-09-08 Csl Limited Reconstituted HDL formulation
CN113842362A (zh) 2012-11-14 2021-12-28 格雷斯公司 含有生物活性材料与无序无机氧化物的组合物
CA3190893A1 (en) * 2013-06-05 2014-12-11 Csl Limited Process for preparing apolipoprotien a-i (apo a-i)
EP3418290A1 (en) 2013-08-08 2018-12-26 CSL Ltd. Contaminant removal method
EP2853259A1 (en) 2013-09-30 2015-04-01 Université Pierre et Marie Curie (Paris 6) Reconstituted high density lipoproteins composition and uses thereof
KR20170003611A (ko) 2014-05-02 2017-01-09 세레니스 쎄라퓨틱스 홀딩 에스에이 Ｈｄｌ 요법 마커
CN105646699B (zh) * 2016-01-15 2019-04-05 新乡医学院 一种利用气相二氧化硅从人血浆中提取载脂蛋白a-1的方法
CA3032229A1 (en) 2016-07-27 2018-02-01 Hartis-Pharma Sa Therapeutic combinations to treat red blood cell disorders
CN107022025A (zh) * 2017-04-17 2017-08-08 深圳职业技术学院 一种纯化α1‑抗胰蛋白酶的方法
CN108239146A (zh) * 2018-03-26 2018-07-03 江苏中新医药有限公司 一种高纯度rhNGF的制备方法
CN108467429A (zh) * 2018-03-26 2018-08-31 江苏中新医药有限公司 疏水层析动态清除重组人神经生长因子前体的方法
CN117209585B (zh) * 2023-11-09 2024-04-05 南京立顶医疗科技有限公司 一种人血清天然脂蛋白(a)的高效提取方法

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Also Published As

Publication number Publication date
WO2009025754A2 (en) 2009-02-26
WO2009025754A3 (en) 2009-04-30
JP2010536758A (ja) 2010-12-02
PL2183268T3 (pl) 2013-03-29
NZ598395A (en) 2013-07-26
EP2183268A2 (en) 2010-05-12
US20140094591A1 (en) 2014-04-03
JP5600061B2 (ja) 2014-10-01
US8653245B2 (en) 2014-02-18
NZ595384A (en) 2012-03-30
CN103408658A (zh) 2013-11-27
EP2520583A1 (en) 2012-11-07
CA2694854C (en) 2016-09-27
EP2522674A1 (en) 2012-11-14
US8436152B2 (en) 2013-05-07
NZ582170A (en) 2012-02-24
KR20100074134A (ko) 2010-07-01
CN101778860A (zh) 2010-07-14
US8962802B2 (en) 2015-02-24
CN103396479A (zh) 2013-11-20
AU2008289543A1 (en) 2009-02-26
SG183743A1 (en) 2012-09-27
DK2183268T3 (da) 2013-01-21
CN101778860B (zh) 2013-07-10
US20130289245A1 (en) 2013-10-31
EP2183268B1 (en) 2012-10-10
ES2397280T3 (es) 2013-03-06
AU2008289543B2 (en) 2011-11-03
CA2694854A1 (en) 2009-02-26
US20110087008A1 (en) 2011-04-14

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