PL2183268T3 - Sposoby oczyszczania alfa-1-antytrypsyny i apolipoproteiny A-I - Google Patents

Sposoby oczyszczania alfa-1-antytrypsyny i apolipoproteiny A-I

Info

Publication number
PL2183268T3
PL2183268T3 PL08795338T PL08795338T PL2183268T3 PL 2183268 T3 PL2183268 T3 PL 2183268T3 PL 08795338 T PL08795338 T PL 08795338T PL 08795338 T PL08795338 T PL 08795338T PL 2183268 T3 PL2183268 T3 PL 2183268T3
Authority
PL
Poland
Prior art keywords
antitrypsin
apolipoprotein
alpha
purification
methods
Prior art date
Application number
PL08795338T
Other languages
English (en)
Inventor
Nathan Brinkman
Douglas Bigler
Reinhard Bolli
Vreni Foertsch
Original Assignee
Csl Behring Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Csl Behring Gmbh filed Critical Csl Behring Gmbh
Publication of PL2183268T3 publication Critical patent/PL2183268T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/775—Apolipopeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8121—Serpins
    • C07K14/8125—Alpha-1-antitrypsin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL08795338T 2007-08-17 2008-08-15 Sposoby oczyszczania alfa-1-antytrypsyny i apolipoproteiny A-I PL2183268T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US93552707P 2007-08-17 2007-08-17
PCT/US2008/009745 WO2009025754A2 (en) 2007-08-17 2008-08-15 Methods for purification of alpha-1-antitrypsin and apolipoprotein a-i
EP08795338A EP2183268B1 (en) 2007-08-17 2008-08-15 Methods for purification of alpha-1-antitrypsin and apolipoprotein a-i

Publications (1)

Publication Number Publication Date
PL2183268T3 true PL2183268T3 (pl) 2013-03-29

Family

ID=39811842

Family Applications (1)

Application Number Title Priority Date Filing Date
PL08795338T PL2183268T3 (pl) 2007-08-17 2008-08-15 Sposoby oczyszczania alfa-1-antytrypsyny i apolipoproteiny A-I

Country Status (13)

Country Link
US (3) US8436152B2 (pl)
EP (3) EP2522674A1 (pl)
JP (1) JP5600061B2 (pl)
KR (1) KR101580907B1 (pl)
CN (3) CN103408658A (pl)
AU (1) AU2008289543B2 (pl)
CA (1) CA2694854C (pl)
DK (1) DK2183268T3 (pl)
ES (1) ES2397280T3 (pl)
NZ (3) NZ582170A (pl)
PL (1) PL2183268T3 (pl)
SG (1) SG183743A1 (pl)
WO (1) WO2009025754A2 (pl)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2183268T3 (pl) 2007-08-17 2013-03-29 Csl Behring Gmbh Sposoby oczyszczania alfa-1-antytrypsyny i apolipoproteiny A-I
JP2012532919A (ja) 2009-07-16 2012-12-20 アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル 治療因子を含むｈｄｌおよび治療における使用
CN102127165B (zh) * 2010-01-15 2013-09-04 上海莱士血液制品股份有限公司 一种从血浆组分四沉淀中制备高纯ApoA-I的生产工艺
HUE032560T2 (en) 2010-06-30 2017-09-28 Csl Ltd Dissolved high density lipoprotein formulation and preparation process
EP4400511A3 (en) 2011-02-07 2024-09-04 Abionyx Pharma SA Lipoprotein complexes and manufacturing and uses thereof
CN102731642B (zh) * 2011-04-14 2014-01-29 上海莱士血液制品股份有限公司 从人血浆组分四沉淀制备高纯Apoa-I的生产工艺
CN102766205B (zh) * 2012-07-25 2013-10-02 深圳市宝凯仑科技有限公司 一种载脂蛋白b的快速纯化方法
US9353165B2 (en) * 2012-07-25 2016-05-31 Grifols, S.A. Purification of cell culture derived alpha1 protease inhibitor
US9534029B2 (en) * 2012-10-03 2017-01-03 Csl Behring Ag Method of purifying proteins
HK1212995A1 (zh) * 2012-10-03 2016-06-24 Csl Behring Ag 一种纯化蛋白质的方法
US9125943B2 (en) 2012-11-02 2015-09-08 Csl Limited Reconstituted HDL formulation
HK1216240A1 (zh) 2012-11-14 2016-10-28 W. R. Grace & Co.-Conn. 含有生物活性材料与无序无机氧化物的组合物
CA2914260C (en) * 2013-06-05 2023-04-18 Csl Limited Process for preparing apolipoprotein a-i (apo a-i)
KR102437202B1 (ko) * 2013-08-08 2022-08-29 시에스엘 리미티드 오염 제거 방법
EP2853259A1 (en) 2013-09-30 2015-04-01 Université Pierre et Marie Curie (Paris 6) Reconstituted high density lipoproteins composition and uses thereof
BR112016025470A2 (pt) 2014-05-02 2017-08-15 Cerenis Therapeutics Holding S A ?hdl terapêutico?
CN105646699B (zh) * 2016-01-15 2019-04-05 新乡医学院 一种利用气相二氧化硅从人血浆中提取载脂蛋白a-1的方法
US12150975B2 (en) 2016-07-27 2024-11-26 Hartis-Pharma Sa Therapeutic combinations to treat red blood cell disorders
CN107022025A (zh) * 2017-04-17 2017-08-08 深圳职业技术学院 一种纯化α1‑抗胰蛋白酶的方法
CN108239146A (zh) * 2018-03-26 2018-07-03 江苏中新医药有限公司 一种高纯度rhNGF的制备方法
CN108467429A (zh) * 2018-03-26 2018-08-31 江苏中新医药有限公司 疏水层析动态清除重组人神经生长因子前体的方法
CN117209585B (zh) * 2023-11-09 2024-04-05 南京立顶医疗科技有限公司 一种人血清天然脂蛋白(a)的高效提取方法

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BE629149A (pl) 1962-03-03
DE3271827D1 (en) 1981-05-01 1986-07-31 Medical Research Inst Of San F Method for isolating alpha-1-antitrypsin
US4820805A (en) 1983-07-14 1989-04-11 New York Blood Center, Inc. Undenatured virus-free trialkyl phosphate treated biologically active protein derivatives
US4697003A (en) 1985-11-01 1987-09-29 Miles Laboratories, Inc. Method of preparing alpha-1-proteinase inhibitor
US4629567A (en) 1986-03-07 1986-12-16 Smithkline-Rit Alpha-1-antiprotease purification
US4876241A (en) 1987-05-22 1989-10-24 Armour Pharmaceutical Company Stabilization of biological and pharmaceutical products during thermal inactivation of viral and bacterial contaminants
CA1335077C (en) 1988-02-08 1995-04-04 Henri Isliker Process for the manufacture of apolipoproteins from human blood plasma or serum
US6187572B1 (en) 1990-04-16 2001-02-13 Baxter International Inc. Method of inactivation of viral and bacterial blood contaminants
CA2112674C (en) 1991-07-02 2005-10-04 John S. Patton Method and device for delivering aerosolized medicaments
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US6096216A (en) 1994-06-09 2000-08-01 American National Red Cross Iodinated matrices for disinfecting biological fluids
US6284874B1 (en) 1994-06-17 2001-09-04 Alpha Therapeutic Corporation Process for separating α1-proteinase inhibitor from cohn fraction IV1 and IV4 paste
US5610285A (en) 1994-08-24 1997-03-11 Bayer Corporation Purification of α-1 proteinase inhibitor using novel chromatographic separation conditions
US5780014A (en) 1995-04-14 1998-07-14 Inhale Therapeutic Systems Method and apparatus for pulmonary administration of dry powder alpha 1-antitrypsin
DE69738397D1 (de) 1996-08-23 2008-01-31 Esperion Therapeutics Inc Verfahren zur aufreinigung von apolipoprotein-a oder apolipoprotein-e aus menschlichem plasma
AT407114B (de) 1997-06-10 2000-12-27 Immuno Ag Alpha 1-antitrypsin-präparation sowie verfahren zu deren herstellung
US6369048B1 (en) 1998-01-12 2002-04-09 V.I. Technologies, Inc. Methods and compositions for inactivating viruses
US6093804A (en) 1998-09-24 2000-07-25 American National Red Cross Method for purification of alpha-1 proteinase inhibitor
US6106773A (en) 1998-09-24 2000-08-22 American National Red Cross Pathogen inactivating compositions for disinfecting biological fluids
US6436344B1 (en) 1999-11-02 2002-08-20 American National Red Cross Method of inactivating pathogens
US7777006B2 (en) * 2002-12-31 2010-08-17 Csl Behring L.L.C. Method for purification of alpha-1-antitrypsin
ATE391730T1 (de) 2003-09-22 2008-04-15 Kamada Ltd Herstellung eines alpha-1-proteinaseinhibitors im grossmassstab und dessen verwendung
RU2346996C2 (ru) 2004-06-29 2009-02-20 ЮРОПИЭН НИКЕЛЬ ПиЭлСи Усовершенствованное выщелачивание основных металлов
EP1786273B1 (en) * 2004-08-20 2018-11-14 ProMetic BioSciences Ltd. Sequential protein isolation and purification schemes by affinity chromatography
DE602006020138D1 (de) 2005-06-29 2011-03-31 Compumedics Ltd Sensoranordnung mit leitfähiger brücke
GB2446550B (en) * 2005-11-28 2010-12-08 Proteomtech Inc Methods for production of recombinant alpha1-antitrypsin
WO2007063129A2 (en) 2005-12-02 2007-06-07 Novozymes A/S Insolation of peptides , polypeptides and proteins
PL2183268T3 (pl) 2007-08-17 2013-03-29 Csl Behring Gmbh Sposoby oczyszczania alfa-1-antytrypsyny i apolipoproteiny A-I

Also Published As

Publication number Publication date
EP2183268B1 (en) 2012-10-10
US20110087008A1 (en) 2011-04-14
AU2008289543B2 (en) 2011-11-03
AU2008289543A1 (en) 2009-02-26
EP2183268A2 (en) 2010-05-12
CA2694854C (en) 2016-09-27
CA2694854A1 (en) 2009-02-26
CN103396479A (zh) 2013-11-20
DK2183268T3 (da) 2013-01-21
NZ582170A (en) 2012-02-24
US8653245B2 (en) 2014-02-18
US20130289245A1 (en) 2013-10-31
KR101580907B1 (ko) 2015-12-29
JP5600061B2 (ja) 2014-10-01
CN101778860A (zh) 2010-07-14
KR20100074134A (ko) 2010-07-01
US8436152B2 (en) 2013-05-07
CN101778860B (zh) 2013-07-10
NZ598395A (en) 2013-07-26
EP2522674A1 (en) 2012-11-14
EP2520583A1 (en) 2012-11-07
SG183743A1 (en) 2012-09-27
JP2010536758A (ja) 2010-12-02
US8962802B2 (en) 2015-02-24
WO2009025754A2 (en) 2009-02-26
WO2009025754A3 (en) 2009-04-30
NZ595384A (en) 2012-03-30
US20140094591A1 (en) 2014-04-03
ES2397280T3 (es) 2013-03-06
CN103408658A (zh) 2013-11-27

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