KR101555731B1 - 클로람페니콜 아세틸 트랜스퍼라아제(ｃａｔ)-결손성 소마토스타틴 융합 단백질 및 그것의 용도 - Google Patents

클로람페니콜 아세틸 트랜스퍼라아제(ｃａｔ)-결손성 소마토스타틴 융합 단백질 및 그것의 용도 Download PDF

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KR101555731B1
KR101555731B1 KR1020107029180A KR20107029180A KR101555731B1 KR 101555731 B1 KR101555731 B1 KR 101555731B1 KR 1020107029180 A KR1020107029180 A KR 1020107029180A KR 20107029180 A KR20107029180 A KR 20107029180A KR 101555731 B1 KR101555731 B1 KR 101555731B1
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seq
somatostatin
phe
amino acid
acid sequence
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KR20110039517A (ko
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앤드류 알. 멘델슨
케이트 엔. 하퍼
제임스 래릭
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브라아쉬 바이오테크 엘엘씨
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/60—Feeding-stuffs specially adapted for particular animals for weanlings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/31—Somatostatins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12N9/1033—Chloramphenicol O-acetyltransferase (2.3.1.28)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y203/00—Acyltransferases (2.3)
    • C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01028—Chloramphenicol O-acetyltransferase (2.3.1.28)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Polymers & Plastics (AREA)
  • Endocrinology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Mycology (AREA)
  • Birds (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Husbandry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
KR1020107029180A 2008-06-25 2008-06-25 클로람페니콜 아세틸 트랜스퍼라아제(ｃａｔ)-결손성 소마토스타틴 융합 단백질 및 그것의 용도 Expired - Fee Related KR101555731B1 (ko)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2008/068195 WO2009157926A1 (en) 2008-06-25 2008-06-25 Chloramphenicol acetyl transferase (cat)-defective somatostatin fusion protein and uses thereof

Publications (2)

Publication Number Publication Date
KR20110039517A KR20110039517A (ko) 2011-04-19
KR101555731B1 true KR101555731B1 (ko) 2015-09-25

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KR1020107029180A Expired - Fee Related KR101555731B1 (ko) 2008-06-25 2008-06-25 클로람페니콜 아세틸 트랜스퍼라아제(ｃａｔ)-결손성 소마토스타틴 융합 단백질 및 그것의 용도

Country Status (15)

Country Link
US (3) US7722881B2 (https=)
EP (1) EP2303314B1 (https=)
JP (1) JP5506792B2 (https=)
KR (1) KR101555731B1 (https=)
CN (1) CN102105163B (https=)
AU (1) AU2008358353B2 (https=)
CA (1) CA2728734A1 (https=)
DK (1) DK2303314T3 (https=)
ES (1) ES2445403T3 (https=)
IL (1) IL209792A (https=)
MX (1) MX2010014082A (https=)
NZ (1) NZ590011A (https=)
RU (1) RU2501565C2 (https=)
WO (1) WO2009157926A1 (https=)
ZA (1) ZA201009125B (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2303314B1 (en) 2008-06-25 2013-12-11 Braasch Biotech LLC Chloramphenicol acetyl transferase (cat)-defective somatostatin fusion protein and uses thereof in cattle
NZ590010A (en) 2008-06-25 2013-01-25 Braasch Biotech Llc Compositions and methods treating growth hormone deficiency and/or an insulin-like growth factor 1 deficiency with somatostatin and an adjuvant
SG11201408287RA (en) * 2012-06-26 2015-01-29 Biovalence Sdn Bhd Rapid specific pathogen free animal
MX365599B (es) 2012-11-08 2019-06-07 Phi Pharma Sa Moleculas de transporte especificas de proteoglicano c4s.
RU2526571C1 (ru) * 2013-04-08 2014-08-27 Сергей Михайлович Юдин Инъекционный препарат для повышения спермопродукции человека и способ его применения
US10441652B2 (en) * 2014-08-21 2019-10-15 Braasch Biotech Llc Methods for improving immunological response in vaccinated animals
WO2021024020A1 (en) 2019-08-06 2021-02-11 Astellas Pharma Inc. Combination therapy involving antibodies against claudin 18.2 and immune checkpoint inhibitors for treatment of cancer
JP7727389B2 (ja) * 2020-02-11 2025-08-21 ブラッシュ・バイオテック・エルエルシー 乳房炎の処置及び／又は予防のための組成物

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005066344A2 (en) 2004-01-09 2005-07-21 Instytut Biotechnologii I Antybiotykow New plasmids, their derivatives and fragments, their methods of manufacture and application

Family Cites Families (11)

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Publication number Priority date Publication date Assignee Title
US4342832A (en) * 1979-07-05 1982-08-03 Genentech, Inc. Method of constructing a replicable cloning vehicle having quasi-synthetic genes
US4446235A (en) * 1982-03-22 1984-05-01 Genentech, Inc. Method for cloning human growth hormone varient genes
ATE163013T1 (de) 1987-11-04 1998-02-15 Byk Gulden Lomberg Chem Fab Alveolare oberflächenaktive proteine
US6316004B1 (en) * 1993-06-22 2001-11-13 T. Tikhonenko Chimeric somatostatin containing protein and encoding DNA, plasmids of expression, method for preparing chimeric protein, strain-producers, immunogenic composition, method for increasing the productivity of farm animals
RU2034457C1 (ru) * 1993-06-22 1995-05-10 Товарищество с ограниченной ответственностью "Ветек" Способ повышения продуктивности сельскохозяйственных животных и препарат для его осуществления
US6025368A (en) * 1997-02-25 2000-02-15 Celtrix Pharmaceuticals, Inc. Method for treating the symptoms of chronic stress-related disorders using IGF
US20070048860A1 (en) * 1997-10-10 2007-03-01 The Government Of The Usa, As Represented By The Secretary, Department Of Health And Human Services Carcinoembryonic antigen (CEA) peptides
US7998930B2 (en) * 2004-11-04 2011-08-16 Hanall Biopharma Co., Ltd. Modified growth hormones
ZA200711123B (en) * 2005-06-27 2009-08-26 Biovail Lab Int Srl Modified-release formulations of a bupropion salt
EP2303314B1 (en) * 2008-06-25 2013-12-11 Braasch Biotech LLC Chloramphenicol acetyl transferase (cat)-defective somatostatin fusion protein and uses thereof in cattle
NZ590010A (en) 2008-06-25 2013-01-25 Braasch Biotech Llc Compositions and methods treating growth hormone deficiency and/or an insulin-like growth factor 1 deficiency with somatostatin and an adjuvant

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005066344A2 (en) 2004-01-09 2005-07-21 Instytut Biotechnologii I Antybiotykow New plasmids, their derivatives and fragments, their methods of manufacture and application

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Biochem J. 1993, Vol. 290, pp.15-19.

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Publication number Publication date
AU2008358353A1 (en) 2009-12-30
ES2445403T3 (es) 2014-03-03
EP2303314A4 (en) 2012-07-18
US20100136037A1 (en) 2010-06-03
US7722881B2 (en) 2010-05-25
ZA201009125B (en) 2012-06-27
IL209792A0 (en) 2011-02-28
CN102105163B (zh) 2014-12-10
US20090324629A1 (en) 2009-12-31
JP2011525914A (ja) 2011-09-29
MX2010014082A (es) 2011-04-07
DK2303314T3 (da) 2014-01-13
CA2728734A1 (en) 2009-12-30
NZ590011A (en) 2012-09-28
AU2008358353B2 (en) 2013-11-07
EP2303314B1 (en) 2013-12-11
BRPI0822826A2 (pt) 2015-07-07
IL209792A (en) 2012-12-31
RU2501565C2 (ru) 2013-12-20
US8367073B2 (en) 2013-02-05
EP2303314A1 (en) 2011-04-06
WO2009157926A1 (en) 2009-12-30
CN102105163A (zh) 2011-06-22
US7943143B2 (en) 2011-05-17
RU2011100104A (ru) 2012-07-20
JP5506792B2 (ja) 2014-05-28
US20120076806A1 (en) 2012-03-29
KR20110039517A (ko) 2011-04-19

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