KR101521484B1 - 메모리 t세포를 주성분으로 하는 림프구 세포군의 제조 방법 - Google Patents

메모리 t세포를 주성분으로 하는 림프구 세포군의 제조 방법 Download PDF

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KR101521484B1
KR101521484B1 KR1020147027998A KR20147027998A KR101521484B1 KR 101521484 B1 KR101521484 B1 KR 101521484B1 KR 1020147027998 A KR1020147027998 A KR 1020147027998A KR 20147027998 A KR20147027998 A KR 20147027998A KR 101521484 B1 KR101521484 B1 KR 101521484B1
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cells
culture
lymphocyte
cell
memory
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KR1020147027998A
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KR20140145585A (ko
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테루아키 세키네
카즈오키 오수미
케이이치로 코모리
노리오 쉬미츠
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가부시키가이샤 림포텍
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/46Cellular immunotherapy
    • A61K39/461Cellular immunotherapy characterised by the cell type used
    • A61K39/4611T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/46Cellular immunotherapy
    • A61K39/464Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/4643Vertebrate antigens
    • A61K39/4644Cancer antigens
    • A61K39/464499Undefined tumor antigens, e.g. tumor lysate or antigens targeted by cells isolated from tumor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0636T lymphocytes

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
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  • Immunology (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
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  • Wood Science & Technology (AREA)
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  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
KR1020147027998A 2012-04-10 2013-04-09 메모리 t세포를 주성분으로 하는 림프구 세포군의 제조 방법 KR101521484B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JPJP-P-2012-088926 2012-04-10
JP2012088926A JP6142142B2 (ja) 2012-04-10 2012-04-10 メモリーt細胞を主成分とするリンパ球細胞群の製造方法
PCT/JP2013/002405 WO2013153800A1 (ja) 2012-04-10 2013-04-09 メモリーt細胞を主成分とするリンパ球細胞群の製造方法

Publications (2)

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KR20140145585A KR20140145585A (ko) 2014-12-23
KR101521484B1 true KR101521484B1 (ko) 2015-06-05

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KR1020147027998A KR101521484B1 (ko) 2012-04-10 2013-04-09 메모리 t세포를 주성분으로 하는 림프구 세포군의 제조 방법

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JP (1) JP6142142B2 (ja)
KR (1) KR101521484B1 (ja)
CN (1) CN104204195B (ja)
HK (1) HK1205181A1 (ja)
WO (1) WO2013153800A1 (ja)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6424447B2 (ja) 2014-03-28 2018-11-21 東洋製罐グループホールディングス株式会社 細胞培養方法、及び細胞培養システム
KR101922322B1 (ko) 2014-07-22 2018-11-26 가부시키가이샤 간멘에키켄큐쇼 말초 순환 암세포의 검출 방법 및 검출 장치
KR101984074B1 (ko) 2015-01-30 2019-05-30 도요세이칸 그룹 홀딩스 가부시키가이샤 세포 배양 방법 및 세포 배양 장치
CN107384859A (zh) * 2017-09-05 2017-11-24 四川新生命干细胞科技股份有限公司 一种高纯度nk细胞的分离培养方法
US20200277573A1 (en) * 2017-11-17 2020-09-03 Iovance Biotherapeutics, Inc. Til expansion from fine needle aspirates and small biopsies
JP2021533759A (ja) * 2018-08-10 2021-12-09 ユーティレックス カンパニー リミテッド 癌抗原特異的cd8+t細胞を調製および凍結保存するための方法
CN109628396B (zh) * 2019-01-24 2021-03-26 清华大学 记忆性淋巴细胞群在肝癌治疗中的应用
CN113005081B (zh) * 2019-12-20 2023-12-19 苏州依科赛生物科技股份有限公司 一种扩增干细胞样记忆性t细胞的培养方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4395644B2 (ja) * 1999-07-08 2010-01-13 株式会社リンフォテック 投与用製剤の製造方法

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JP4389039B2 (ja) * 1998-04-09 2009-12-24 株式会社リンフォテック アロジェニックな活性化cd4陽性細胞を主成分とする医薬組成物、およびその製造方法、ならびに該医薬組成物調製用キット
JP4385158B2 (ja) * 2000-12-04 2009-12-16 株式会社リンフォテック 細胞の保存液および該保存液を用いた細胞の保存方法
JP4917201B2 (ja) * 2000-12-04 2012-04-18 株式会社リンフォテック 臍帯血移植後の腫瘍および各種感染症の予防・治療用製剤、臍帯血移植後の移植臍帯血幹細胞の生着促進用製剤、臍帯血移植後の腫瘍および各種感染症の予防・治療用製剤ならびに臍帯血移植後の移植臍帯血幹細胞の生着促進用製剤の製造方法。
EP1347040B1 (en) * 2000-12-04 2006-01-11 Lymphotec Inc. Cell-preservation liquid and method of preserving cells by using the liquid
PL2613801T3 (pl) * 2010-09-08 2016-12-30 Zastosowanie komórek T pamięci centralnych przeciwko obcym antygenom do leczenia białaczki/chłoniaka

Patent Citations (1)

* Cited by examiner, † Cited by third party
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JP4395644B2 (ja) * 1999-07-08 2010-01-13 株式会社リンフォテック 投与用製剤の製造方法

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
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Biotherapy, 2009, Vol.23, No.3, p. 257-262 *
Cell Immunol.,1991, Vol.133 (1), p. 206-218 *
CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY, 2000, Vol. 7, No. 3, p. 352-359 *

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Publication number Publication date
CN104204195A (zh) 2014-12-10
WO2013153800A1 (ja) 2013-10-17
JP2013215141A (ja) 2013-10-24
CN104204195B (zh) 2017-07-18
KR20140145585A (ko) 2014-12-23
HK1205181A1 (en) 2015-12-11
JP6142142B2 (ja) 2017-06-07

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