KR101497509B1 - 트라마돌의 부작용을 감소시키는 방법 - Google Patents

트라마돌의 부작용을 감소시키는 방법 Download PDF

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KR101497509B1
KR101497509B1 KR1020097018879A KR20097018879A KR101497509B1 KR 101497509 B1 KR101497509 B1 KR 101497509B1 KR 1020097018879 A KR1020097018879 A KR 1020097018879A KR 20097018879 A KR20097018879 A KR 20097018879A KR 101497509 B1 KR101497509 B1 KR 101497509B1
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pharmaceutically acceptable
acceptable salt
tramadol
combination
sildenafil
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Korean (ko)
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KR20090127277A (ko
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데이비드 바-오
케빈 빌야드
제임스 브이. 윙클러
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브릭스 파마슈티컬스 인코퍼레이티드
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Assigned to 아이트 바이오사이언스, 아이엔씨. reassignment 아이트 바이오사이언스, 아이엔씨. 권리의 전부이전등록 Assignors: 브릭스 파마슈티컬스 인코퍼레이티드
Assigned to 주식회사 대웅제약 reassignment 주식회사 대웅제약 권리의 전부이전등록 Assignors: 아이트 바이오사이언스, 아이엔씨.
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pain & Pain Management (AREA)
  • Gynecology & Obstetrics (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020097018879A 2007-02-12 2008-02-12 트라마돌의 부작용을 감소시키는 방법 Active KR101497509B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US88938007P 2007-02-12 2007-02-12
US60/889,380 2007-02-12
PCT/US2008/053722 WO2008100933A2 (en) 2007-02-12 2008-02-12 Reducing side effects of tramadol

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020137027225A Division KR20130122023A (ko) 2007-02-12 2008-02-12 트라마돌의 부작용을 감소시키는 방법

Publications (2)

Publication Number Publication Date
KR20090127277A KR20090127277A (ko) 2009-12-10
KR101497509B1 true KR101497509B1 (ko) 2015-03-03

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Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020097018879A Active KR101497509B1 (ko) 2007-02-12 2008-02-12 트라마돌의 부작용을 감소시키는 방법
KR1020137027225A Withdrawn KR20130122023A (ko) 2007-02-12 2008-02-12 트라마돌의 부작용을 감소시키는 방법

Family Applications After (1)

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KR1020137027225A Withdrawn KR20130122023A (ko) 2007-02-12 2008-02-12 트라마돌의 부작용을 감소시키는 방법

Country Status (16)

Country Link
US (3) US20080261991A1 (https=)
EP (2) EP2114147B9 (https=)
JP (1) JP5550101B2 (https=)
KR (2) KR101497509B1 (https=)
CN (1) CN101674728A (https=)
AU (1) AU2008216363B2 (https=)
BR (1) BRPI0807281A2 (https=)
CA (1) CA2677691C (https=)
DK (1) DK2114147T3 (https=)
ES (1) ES2384127T3 (https=)
MX (1) MX2009008511A (https=)
NZ (1) NZ579170A (https=)
PL (1) PL2114147T3 (https=)
SG (1) SG178775A1 (https=)
WO (1) WO2008100933A2 (https=)
ZA (1) ZA200906187B (https=)

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CN101674728A (zh) * 2007-02-12 2010-03-17 Dmi生物科学公司 降低曲马多的副作用
CA2677690C (en) * 2007-02-12 2012-05-15 James V. Winkler Treatment of comorbid premature ejaculation and erectile dysfunction
CA2785056A1 (en) 2009-12-22 2011-07-21 Pondera Biotechnologies, LLC Methods and compositions for treating distress dysfunction and enhancing safety and efficacy of specific medications
CA2833307C (en) * 2011-04-12 2018-01-23 Revogenex Inc. Intravenous administration of tramadol
WO2015134695A1 (en) * 2014-03-07 2015-09-11 Vyrix Pharmaceuticals, Inc. Method of mitigating the side effects of a phosphodiesterase type v inhibitor in a subject
US20160228485A1 (en) * 2015-02-11 2016-08-11 Latasha M. Watts Skin medicating system
US9980900B2 (en) 2015-12-22 2018-05-29 Revogenex Ireland Ltd Intravenous administration of tramadol
US9693949B1 (en) 2015-12-22 2017-07-04 Revogenex Ireland Ltd Intravenous administration of tramadol
US10022321B2 (en) 2016-06-30 2018-07-17 Revogenex Ireland Ltd. Intravenous administration of tramadol
WO2020006606A1 (en) * 2018-07-05 2020-01-09 Helium 3 Resources Pty Ltd A pharmaceutical composition and method of use of same
US12599554B2 (en) 2020-07-29 2026-04-14 Kydes Pharmaceuticals Llc Pharmaceutical formulations comprising tadalafil
US11504332B2 (en) * 2021-03-23 2022-11-22 Vk Research Associates Inc. Phosphodiesterase-4 inhibitor combinations, methods of making, and methods of use thereof
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KR20040052490A (ko) * 2001-03-16 2004-06-23 디엠아이 바이오사이언스 인코포레이티드 사정 지연 방법

Also Published As

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US20080261991A1 (en) 2008-10-23
PL2114147T3 (pl) 2012-10-31
EP2114147B1 (en) 2012-05-16
NZ579170A (en) 2012-05-25
ZA200906187B (en) 2013-02-27
EP2114147B9 (en) 2013-04-10
KR20090127277A (ko) 2009-12-10
CA2677691C (en) 2012-07-31
MX2009008511A (es) 2010-01-20
WO2008100933A2 (en) 2008-08-21
AU2008216363B2 (en) 2014-05-08
WO2008100933A3 (en) 2008-10-16
SG178775A1 (en) 2012-03-29
JP5550101B2 (ja) 2014-07-16
EP2486921A1 (en) 2012-08-15
EP2114147A4 (en) 2010-04-07
EP2114147A2 (en) 2009-11-11
CA2677691A1 (en) 2008-08-21
JP2010518168A (ja) 2010-05-27
ES2384127T3 (es) 2012-06-29
AU2008216363A1 (en) 2008-08-21
CN101674728A (zh) 2010-03-17
HK1131730A1 (en) 2010-02-05
DK2114147T3 (da) 2012-06-25
US20130338166A1 (en) 2013-12-19
KR20130122023A (ko) 2013-11-06
US20120018333A1 (en) 2012-01-26
BRPI0807281A2 (pt) 2014-04-29

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PA0105 International application

Patent event date: 20090909

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