KR101440171B1 - 세포 팽창 장치에 사용하기 위한 일회용 배관 세트 및 무균 샘플링 방법 - Google Patents

세포 팽창 장치에 사용하기 위한 일회용 배관 세트 및 무균 샘플링 방법 Download PDF

Info

Publication number
KR101440171B1
KR101440171B1 KR1020097020706A KR20097020706A KR101440171B1 KR 101440171 B1 KR101440171 B1 KR 101440171B1 KR 1020097020706 A KR1020097020706 A KR 1020097020706A KR 20097020706 A KR20097020706 A KR 20097020706A KR 101440171 B1 KR101440171 B1 KR 101440171B1
Authority
KR
South Korea
Prior art keywords
cell growth
cell
tube
sample
region
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
KR1020097020706A
Other languages
English (en)
Korean (ko)
Other versions
KR20090121372A (ko
Inventor
글렌 델버트 앤트윌러
Original Assignee
테루모 비씨티, 인크.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 테루모 비씨티, 인크. filed Critical 테루모 비씨티, 인크.
Publication of KR20090121372A publication Critical patent/KR20090121372A/ko
Application granted granted Critical
Publication of KR101440171B1 publication Critical patent/KR101440171B1/ko
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/42—Integrated assemblies, e.g. cassettes or cartridges
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C12M1/26—Inoculator or sampler
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/28—Constructional details, e.g. recesses, hinges disposable or single use
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/48—Holding appliances; Racks; Supports
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/04—Filters; Permeable or porous membranes or plates, e.g. dialysis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Clinical Laboratory Science (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
KR1020097020706A 2007-03-01 2008-01-28 세포 팽창 장치에 사용하기 위한 일회용 배관 세트 및 무균 샘플링 방법 Expired - Fee Related KR101440171B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US89246007P 2007-03-01 2007-03-01
US60/892,460 2007-03-01
US97138207P 2007-09-11 2007-09-11
US60/971,382 2007-09-11
PCT/US2008/052185 WO2008109200A1 (en) 2007-03-01 2008-01-28 Disposable tubing set for use with a cell expansion apparatus and method for sterile sampling

Publications (2)

Publication Number Publication Date
KR20090121372A KR20090121372A (ko) 2009-11-25
KR101440171B1 true KR101440171B1 (ko) 2014-09-15

Family

ID=39522125

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020097020706A Expired - Fee Related KR101440171B1 (ko) 2007-03-01 2008-01-28 세포 팽창 장치에 사용하기 위한 일회용 배관 세트 및 무균 샘플링 방법

Country Status (8)

Country Link
US (2) US7718430B2 (https=)
EP (1) EP2115117A1 (https=)
JP (1) JP5149313B2 (https=)
KR (1) KR101440171B1 (https=)
CN (1) CN101622337B (https=)
AU (1) AU2008223280B2 (https=)
CA (1) CA2679097C (https=)
WO (1) WO2008109200A1 (https=)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5149313B2 (ja) * 2007-03-01 2013-02-20 テルモ ビーシーティー、インコーポレーテッド 細胞増殖装置と共に使用するためのディスポーザブル配管セット、および無菌サンプリング方法
ES2665024T3 (es) * 2007-03-05 2018-04-24 Terumo Bct, Inc. Métodos para controlar el movimiento celular en biorreactores de fibra hueca
JP2010519937A (ja) 2007-03-05 2010-06-10 カリディアンビーシーティー、インコーポレーテッド 細胞増殖システムおよび使用方法
US9284523B2 (en) 2008-10-27 2016-03-15 Terumo Bct, Inc. Premounted fluid conveyance assembly for cell expansion system and method of use associated therewith
US8399245B2 (en) * 2009-02-18 2013-03-19 Terumo Bct, Inc. Rotation system for cell growth chamber of a cell expansion system and method of use therefor
EP2414508A4 (en) * 2009-04-03 2015-05-06 Xcellerex Inc TISSUE AND ORGAN TRANSPLANT BIOREACTOR AND OPERATING PROCEDURES
GB0906836D0 (en) * 2009-04-21 2009-06-03 Cymtox Ltd Consumable component kit
US9057045B2 (en) * 2009-12-29 2015-06-16 Terumo Bct, Inc. Method of loading and distributing cells in a bioreactor of a cell expansion system
WO2011126650A1 (en) 2010-04-09 2011-10-13 Caridianbct, Inc. Air removal chamber for a cell expansion system and method of use associated therewith
CA2812774A1 (en) * 2010-10-01 2012-04-05 Zevex, Inc. Method for improving accuracy in a peristaltic pump system based on tubing material properties
WO2012048276A2 (en) 2010-10-08 2012-04-12 Caridianbct, Inc. Customizable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system
PL2718416T3 (pl) 2011-06-06 2020-05-18 ReGenesys BVBA Namnażanie komórek macierzystych w bioreaktorach włóknisto-kapilarnych
DE102012200938B4 (de) * 2012-01-23 2016-08-18 Alpha Plan Gmbh Bio- und medizintechnisches Baukastensystem
CN104583386A (zh) * 2012-08-20 2015-04-29 泰尔茂比司特公司 浓缩穿过细胞生长腔室循环的流体的组分
CN104540933A (zh) * 2012-08-20 2015-04-22 泰尔茂比司特公司 在细胞扩增系统的生物反应器中加载和分配细胞的方法
WO2015073913A1 (en) 2013-11-16 2015-05-21 Terumo Bct, Inc. Expanding cells in a bioreactor
WO2015148704A1 (en) 2014-03-25 2015-10-01 Terumo Bct, Inc. Passive replacement of media
US10077421B2 (en) 2014-04-24 2018-09-18 Terumo Bct, Inc. Measuring flow rate
EP3198006B1 (en) 2014-09-26 2021-03-24 Terumo BCT, Inc. Scheduled feed
WO2017004592A1 (en) 2015-07-02 2017-01-05 Terumo Bct, Inc. Cell growth with mechanical stimuli
CN105087380A (zh) * 2015-07-31 2015-11-25 南方医科大学珠江医院 大规模培养动物细胞的系统
GB201600315D0 (en) 2015-08-13 2016-02-24 Gen Electric Heatseal sampling
US11965175B2 (en) 2016-05-25 2024-04-23 Terumo Bct, Inc. Cell expansion
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
CN115044471B (zh) 2016-08-27 2025-05-27 三维生物科技有限公司 生物反应器
KR102499475B1 (ko) 2017-02-10 2023-02-15 론자 리미티드 세포 배양 시스템 및 방법
CN117247899A (zh) 2017-03-31 2023-12-19 泰尔茂比司特公司 细胞扩增
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
US10696961B2 (en) 2017-12-01 2020-06-30 Global Life Sciences Solutions Usa Llc Magnetic cell isolation techniques
US12077743B2 (en) 2018-02-09 2024-09-03 Global Life Sciences Solutions Usa Llc Apparatus for fluid line management in a bioprocessing system
US10889792B2 (en) 2018-02-09 2021-01-12 Global Life Sciences Solutions Usa Llc Cell expansion vessel systems and methods
JP7520322B2 (ja) * 2018-02-09 2024-07-23 グローバル・ライフ・サイエンシズ・ソリューションズ・ユーエスエー・エルエルシー 細胞療法のためのバイオプロセッシング方法
US11920119B2 (en) 2018-02-09 2024-03-05 Global Life Sciences Solutions Usa Llc Systems and methods for bioprocessing
US11371007B2 (en) 2018-02-09 2022-06-28 Global Life Sciences Solutions Usa Llc System and method for fluid flow management in a bioprocessing system
US11932842B2 (en) 2018-02-09 2024-03-19 Global Life Sciences Solutions Usa Llc Bioprocessing apparatus
US12252682B2 (en) 2018-02-09 2025-03-18 Global Life Sciences Solutions Usa Llc System and method for fluid flow management in a bioprocessing system
US11414639B2 (en) 2018-02-09 2022-08-16 Global Life Sciences Solutions Usa Llc Bioprocessing vessel
JP7225796B2 (ja) * 2018-12-27 2023-02-21 大日本印刷株式会社 サンプリング機能付き容器
WO2021157712A1 (en) * 2020-02-06 2021-08-12 Terumo Kabushiki Kaisha Flow path cassette, cell culturing kit, and cell culturing system
GB202017182D0 (en) * 2020-10-29 2020-12-16 Cytiva Sweden Ab Fluid coupling network for sampling a bioreactor
WO2023122133A1 (en) * 2021-12-22 2023-06-29 Pbs Biotech, Inc. Apparatus and methods for treating media in large-scale bioreactors
US12521474B2 (en) 2022-03-10 2026-01-13 Terumo Bct, Inc. Soft cassette with integrated features
US12379916B2 (en) 2022-03-10 2025-08-05 Terumo Bct, Inc. Communications and operation control of apheresis systems
US12458740B2 (en) 2022-03-10 2025-11-04 Terumo Bct, Inc. Modular serviceability sleds and interconnections
US12599710B2 (en) 2022-03-10 2026-04-14 Terumo Bct, Inc. Methods and interfaces for providing donation process feedback
US12478551B2 (en) 2022-03-10 2025-11-25 Terumo Bct, Inc. Collection bottle with integrated cap, handle, and shield features
WO2025207793A1 (en) * 2024-03-26 2025-10-02 Waters Technologies Corporation Pneumatic transfer of fluid samples over lengthy conduits

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002028996A1 (en) 2000-10-02 2002-04-11 Cannon Thomas F Automated bioculture and bioculture experiments system
US20020146816A1 (en) 2000-10-25 2002-10-10 Vellinger John C. Bioreactor apparatus and cell culturing system
JP2005531300A (ja) * 2002-04-08 2005-10-20 ミレニアム・バイオロジクス，インコーポレイテッド 自動的な組織工学モジュール

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4889812A (en) * 1986-05-12 1989-12-26 C. D. Medical, Inc. Bioreactor apparatus
JPH0576582A (ja) * 1991-09-20 1993-03-30 Hitachi Ltd マイクロ波滅菌方法、その滅菌装置及び培養システム
US7347913B2 (en) * 2001-04-27 2008-03-25 Fenwal, Inc. Sealing apparatus and method
EP1455860B1 (en) * 2001-12-10 2011-08-31 CaridianBCT, Inc. Method for the leukoreduction of red blood cells
JP2005524445A (ja) 2002-05-03 2005-08-18 ガンブロ　　インコーポレーテッド 血液製剤中のバクテリアを検出する装置並びに方法
JP4668568B2 (ja) * 2003-08-26 2011-04-13 株式会社メディネット 培養容器、培養装置および細胞の培養方法
WO2006026835A1 (en) * 2004-09-10 2006-03-16 Unisearch Limited Device and method to prevent culture media degradation
US7919307B2 (en) * 2005-05-09 2011-04-05 Alpha Plan Gmbh Supply system for cell culture module
JP5149313B2 (ja) 2007-03-01 2013-02-20 テルモ ビーシーティー、インコーポレーテッド 細胞増殖装置と共に使用するためのディスポーザブル配管セット、および無菌サンプリング方法

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002028996A1 (en) 2000-10-02 2002-04-11 Cannon Thomas F Automated bioculture and bioculture experiments system
US20020146816A1 (en) 2000-10-25 2002-10-10 Vellinger John C. Bioreactor apparatus and cell culturing system
JP2005531300A (ja) * 2002-04-08 2005-10-20 ミレニアム・バイオロジクス，インコーポレイテッド 自動的な組織工学モジュール

Also Published As

Publication number Publication date
CN101622337A (zh) 2010-01-06
JP5149313B2 (ja) 2013-02-20
CN101622337B (zh) 2013-04-24
JP2010519903A (ja) 2010-06-10
AU2008223280A1 (en) 2008-09-12
AU2008223280B2 (en) 2013-09-19
KR20090121372A (ko) 2009-11-25
CA2679097C (en) 2015-04-28
EP2115117A1 (en) 2009-11-11
US20100144037A1 (en) 2010-06-10
US20080213894A1 (en) 2008-09-04
US8163555B2 (en) 2012-04-24
WO2008109200A1 (en) 2008-09-12
CA2679097A1 (en) 2008-09-12
US7718430B2 (en) 2010-05-18

Similar Documents

Publication Publication Date Title
KR101440171B1 (ko) 세포 팽창 장치에 사용하기 위한 일회용 배관 세트 및 무균 샘플링 방법
US10617569B2 (en) System for wound treatment using a serum
US20080227190A1 (en) Cell Expansion Apparatus with Plate Bioreactor
US12606792B2 (en) Cell concentration methods and devices for use in automated bioreactors
US8906688B2 (en) Cell expansion system and methods of use
JPS62171669A (ja) 細胞を培養し、老廃物を取出し、生産物を濃縮する装置および方法
JP5760254B2 (ja) ろ過装置
WO2025041046A1 (en) Systems, devices, and methods for fluid control in a cell processing system
KR20140147805A (ko) 지방조직으로부터 비지방 세포의 단리를 위한 방법 및 장치
EP4106907B1 (en) Filtration system for cell removal systems and methods of using the same
HK40051570A (en) Cell concentration methods and devices for use in automated bioreactors
HK40103099A (zh) 用於在自动化细胞工程系统中使用的组合流体切换器

Legal Events

Date Code Title Description
PA0105 International application

St.27 status event code: A-0-1-A10-A15-nap-PA0105

E13-X000 Pre-grant limitation requested

St.27 status event code: A-2-3-E10-E13-lim-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

PN2301 Change of applicant

St.27 status event code: A-3-3-R10-R13-asn-PN2301

St.27 status event code: A-3-3-R10-R11-asn-PN2301

A201 Request for examination
P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PA0201 Request for examination

St.27 status event code: A-1-2-D10-D11-exm-PA0201

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

St.27 status event code: A-1-2-D10-D21-exm-PE0902

E13-X000 Pre-grant limitation requested

St.27 status event code: A-2-3-E10-E13-lim-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

R17-X000 Change to representative recorded

St.27 status event code: A-3-3-R10-R17-oth-X000

E701 Decision to grant or registration of patent right
PE0701 Decision of registration

St.27 status event code: A-1-2-D10-D22-exm-PE0701

GRNT Written decision to grant
PR0701 Registration of establishment

St.27 status event code: A-2-4-F10-F11-exm-PR0701

PR1002 Payment of registration fee

St.27 status event code: A-2-2-U10-U12-oth-PR1002

Fee payment year number: 1

PG1601 Publication of registration

St.27 status event code: A-4-4-Q10-Q13-nap-PG1601

R17-X000 Change to representative recorded

St.27 status event code: A-5-5-R10-R17-oth-X000

FPAY Annual fee payment

Payment date: 20170629

Year of fee payment: 4

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 4

FPAY Annual fee payment

Payment date: 20180628

Year of fee payment: 5

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 5

PC1903 Unpaid annual fee

St.27 status event code: A-4-4-U10-U13-oth-PC1903

Not in force date: 20190904

Payment event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

PC1903 Unpaid annual fee

St.27 status event code: N-4-6-H10-H13-oth-PC1903

Ip right cessation event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

Not in force date: 20190904