KR101438546B1 - 프레가발린을 포함하는 서방성 제제 - Google Patents

프레가발린을 포함하는 서방성 제제 Download PDF

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Publication number
KR101438546B1
KR101438546B1 KR1020120092407A KR20120092407A KR101438546B1 KR 101438546 B1 KR101438546 B1 KR 101438546B1 KR 1020120092407 A KR1020120092407 A KR 1020120092407A KR 20120092407 A KR20120092407 A KR 20120092407A KR 101438546 B1 KR101438546 B1 KR 101438546B1
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KR
South Korea
Prior art keywords
agent
pregabalin
swelling
comparative example
amount
Prior art date
Application number
KR1020120092407A
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English (en)
Korean (ko)
Other versions
KR20130023127A (ko
Inventor
이홍우
최재승
박종수
남경태
이송재
Original Assignee
근화제약주식회사
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Application filed by 근화제약주식회사 filed Critical 근화제약주식회사
Publication of KR20130023127A publication Critical patent/KR20130023127A/ko
Application granted granted Critical
Publication of KR101438546B1 publication Critical patent/KR101438546B1/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
KR1020120092407A 2011-08-26 2012-08-23 프레가발린을 포함하는 서방성 제제 KR101438546B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020110085433 2011-08-26
KR20110085433 2011-08-26

Publications (2)

Publication Number Publication Date
KR20130023127A KR20130023127A (ko) 2013-03-07
KR101438546B1 true KR101438546B1 (ko) 2014-09-17

Family

ID=47756576

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020120092407A KR101438546B1 (ko) 2011-08-26 2012-08-23 프레가발린을 포함하는 서방성 제제

Country Status (2)

Country Link
KR (1) KR101438546B1 (fr)
WO (1) WO2013032185A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102221846B1 (ko) * 2014-04-07 2021-02-26 영진약품 주식회사 안정성이 개선된 프레가발린을 함유하는 약제학적 조성물 및 이의 제조방법
KR102039345B1 (ko) * 2017-02-01 2019-11-01 지엘팜텍주식회사 프레가발린 함유 고팽윤성 서방성 삼중정제
KR102039344B1 (ko) * 2017-02-01 2019-11-01 지엘팜텍주식회사 프레가발린 함유 경구용 서방성 삼중정제

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040180088A1 (en) * 2001-07-04 2004-09-16 Dudhara Kamlesh Mohanlal Gastric retention controlled drug delivery system
KR20080059427A (ko) * 2005-11-02 2008-06-27 화이자 프로덕츠 인크. 프리가발린, 매트릭스 형성제 및 팽윤제를 함유하는 1일1회 투여를 위한 경구용 고체 제약 조성물

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006078811A2 (fr) * 2005-01-21 2006-07-27 Pharmanova Inc. Preparations pharmaceutiques qui procedes d'utilisation
KR20100023429A (ko) * 2008-08-22 2010-03-04 제일약품주식회사 당뇨병 복합제의 위체류시스템 서방성 및 속방성 조절을 통한 최적화된 약물송달시스템
KR101317592B1 (ko) * 2009-10-28 2013-10-15 씨제이제일제당 (주) 프레가발린, 폴리에틸렌옥사이드 및 폴리비닐알코올-폴리에틸렌글리콜 그라프트 공중합체를 함유하는 위체류형 서방성 제제
KR101648490B1 (ko) * 2009-11-02 2016-08-17 한미사이언스 주식회사 위체류 약물 전달시스템을 이용한 서방성 경구용 제제

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040180088A1 (en) * 2001-07-04 2004-09-16 Dudhara Kamlesh Mohanlal Gastric retention controlled drug delivery system
KR20080059427A (ko) * 2005-11-02 2008-06-27 화이자 프로덕츠 인크. 프리가발린, 매트릭스 형성제 및 팽윤제를 함유하는 1일1회 투여를 위한 경구용 고체 제약 조성물

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Publication number Publication date
KR20130023127A (ko) 2013-03-07
WO2013032185A1 (fr) 2013-03-07

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