KR101309500B1 - 분리된 계통 음성 조혈 줄기세포 및 이를 사용한 치료 방법 - Google Patents

분리된 계통 음성 조혈 줄기세포 및 이를 사용한 치료 방법 Download PDF

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Publication number
KR101309500B1
KR101309500B1 KR1020077007667A KR20077007667A KR101309500B1 KR 101309500 B1 KR101309500 B1 KR 101309500B1 KR 1020077007667 A KR1020077007667 A KR 1020077007667A KR 20077007667 A KR20077007667 A KR 20077007667A KR 101309500 B1 KR101309500 B1 KR 101309500B1
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South Korea
Prior art keywords
lin
cells
delete delete
hsc
retinal
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KR1020077007667A
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Korean (ko)
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KR20070104512A (ko
Inventor
마틴 프라이드랜터
아쓰시 오타니
카렌 대실바
스테이시 모레노 (핸캠프)
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더 스크립스 리서치 인스티튜트
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Priority claimed from US10/933,634 external-priority patent/US20050129665A1/en
Application filed by 더 스크립스 리서치 인스티튜트 filed Critical 더 스크립스 리서치 인스티튜트
Priority claimed from PCT/US2005/031304 external-priority patent/WO2006031467A2/en
Publication of KR20070104512A publication Critical patent/KR20070104512A/ko
Application granted granted Critical
Publication of KR101309500B1 publication Critical patent/KR101309500B1/ko

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0081—Purging biological preparations of unwanted cells
    • C12N5/0087—Purging against subsets of blood cells, e.g. purging alloreactive T cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Developmental Biology & Embryology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020077007667A 2004-09-03 2005-09-02 분리된 계통 음성 조혈 줄기세포 및 이를 사용한 치료 방법 KR101309500B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/933,634 US20050129665A1 (en) 2002-07-25 2004-09-03 Isolated lineage negative hematopoietic stem cells and methods of treatment therewith
US10/933,634 2004-09-03
PCT/US2005/031304 WO2006031467A2 (en) 2002-07-25 2005-09-02 Isolated lineage negative hematopoietic stem cells and methods of treatment therewith

Publications (2)

Publication Number Publication Date
KR20070104512A KR20070104512A (ko) 2007-10-26
KR101309500B1 true KR101309500B1 (ko) 2013-09-24

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Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020077007667A KR101309500B1 (ko) 2004-09-03 2005-09-02 분리된 계통 음성 조혈 줄기세포 및 이를 사용한 치료 방법

Country Status (8)

Country Link
EP (1) EP1802199A4 (zh)
JP (1) JP2008512376A (zh)
KR (1) KR101309500B1 (zh)
CN (1) CN101052305B (zh)
AU (1) AU2005285246B2 (zh)
CA (1) CA2579292A1 (zh)
MX (1) MX2007002639A (zh)
ZA (1) ZA200702607B (zh)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2554662A1 (en) * 2011-08-05 2013-02-06 M Maria Pia Cosma Methods of treatment of retinal degeneration diseases

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004010959A2 (en) * 2002-07-25 2004-02-05 The Scripps Research Institute Hematopoietic stem cells and methods of treatment of neovascular eye diseases therewith

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5928638A (en) * 1996-06-17 1999-07-27 Systemix, Inc. Methods for gene transfer
US7219016B2 (en) * 2001-04-20 2007-05-15 Yale University Systems and methods for automated analysis of cells and tissues
US6939378B2 (en) * 2001-06-01 2005-09-06 The Board Of Trustees Of The Leland Stanford Junior University Microfabricated tissue as a substrate for pigment epithelium transplantation
JP2005526482A (ja) * 2001-08-10 2005-09-08 イムクローン システムズ インコーポレイティド Ｖｅｇｆｒ−１を発現する幹細胞の単離および動員
KR20050042046A (ko) * 2001-10-30 2005-05-04 다이이찌 세이야꾸 가부시기가이샤 조혈 줄기세포의 증식방법
CN1194086C (zh) * 2002-02-01 2005-03-23 北京科宇联合干细胞生物技术有限公司 一种神经干细胞制剂的制备方法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004010959A2 (en) * 2002-07-25 2004-02-05 The Scripps Research Institute Hematopoietic stem cells and methods of treatment of neovascular eye diseases therewith

Also Published As

Publication number Publication date
EP1802199A2 (en) 2007-07-04
CA2579292A1 (en) 2006-03-23
AU2005285246B2 (en) 2011-07-21
CN101052305A (zh) 2007-10-10
KR20070104512A (ko) 2007-10-26
MX2007002639A (es) 2007-08-06
AU2005285246A1 (en) 2006-03-23
CN101052305B (zh) 2012-10-10
JP2008512376A (ja) 2008-04-24
EP1802199A4 (en) 2008-08-27
ZA200702607B (en) 2008-08-27

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