AU2005285246B2 - Isolated lineage negative hematopoietic stem cells and methods of treatment therewith - Google Patents

Isolated lineage negative hematopoietic stem cells and methods of treatment therewith Download PDF

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Publication number
AU2005285246B2
AU2005285246B2 AU2005285246A AU2005285246A AU2005285246B2 AU 2005285246 B2 AU2005285246 B2 AU 2005285246B2 AU 2005285246 A AU2005285246 A AU 2005285246A AU 2005285246 A AU2005285246 A AU 2005285246A AU 2005285246 B2 AU2005285246 B2 AU 2005285246B2
Authority
AU
Australia
Prior art keywords
cells
lin
hematopoietic stem
hsc
isolated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2005285246A
Other languages
English (en)
Other versions
AU2005285246A1 (en
Inventor
Karen Da Silva
Martin Friedlander
Stacey Moreno (Hanekamp)
Atsushi Otani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scripps Research Institute
Original Assignee
Scripps Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/933,634 external-priority patent/US20050129665A1/en
Application filed by Scripps Research Institute filed Critical Scripps Research Institute
Priority claimed from PCT/US2005/031304 external-priority patent/WO2006031467A2/en
Publication of AU2005285246A1 publication Critical patent/AU2005285246A1/en
Application granted granted Critical
Publication of AU2005285246B2 publication Critical patent/AU2005285246B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0081—Purging biological preparations of unwanted cells
    • C12N5/0087—Purging against subsets of blood cells, e.g. purging alloreactive T cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Developmental Biology & Embryology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2005285246A 2004-09-03 2005-09-02 Isolated lineage negative hematopoietic stem cells and methods of treatment therewith Ceased AU2005285246B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/933,634 2004-09-03
US10/933,634 US20050129665A1 (en) 2002-07-25 2004-09-03 Isolated lineage negative hematopoietic stem cells and methods of treatment therewith
PCT/US2005/031304 WO2006031467A2 (en) 2002-07-25 2005-09-02 Isolated lineage negative hematopoietic stem cells and methods of treatment therewith

Publications (2)

Publication Number Publication Date
AU2005285246A1 AU2005285246A1 (en) 2006-03-23
AU2005285246B2 true AU2005285246B2 (en) 2011-07-21

Family

ID=37903853

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2005285246A Ceased AU2005285246B2 (en) 2004-09-03 2005-09-02 Isolated lineage negative hematopoietic stem cells and methods of treatment therewith

Country Status (8)

Country Link
EP (1) EP1802199A4 (zh)
JP (1) JP2008512376A (zh)
KR (1) KR101309500B1 (zh)
CN (1) CN101052305B (zh)
AU (1) AU2005285246B2 (zh)
CA (1) CA2579292A1 (zh)
MX (1) MX2007002639A (zh)
ZA (1) ZA200702607B (zh)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2554662A1 (en) * 2011-08-05 2013-02-06 M Maria Pia Cosma Methods of treatment of retinal degeneration diseases

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004010959A2 (en) * 2002-07-25 2004-02-05 The Scripps Research Institute Hematopoietic stem cells and methods of treatment of neovascular eye diseases therewith

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5928638A (en) * 1996-06-17 1999-07-27 Systemix, Inc. Methods for gene transfer
US7219016B2 (en) * 2001-04-20 2007-05-15 Yale University Systems and methods for automated analysis of cells and tissues
US6939378B2 (en) * 2001-06-01 2005-09-06 The Board Of Trustees Of The Leland Stanford Junior University Microfabricated tissue as a substrate for pigment epithelium transplantation
ATE378056T1 (de) * 2001-08-10 2007-11-15 Imclone Systems Inc Medizinische verwendung von stammzellen, die vegfr-1 exprimieren
WO2003038077A1 (fr) * 2001-10-30 2003-05-08 Daiichi Pharmaceutical Co., Ltd. Procede d'amplification des cellules hematopoietiques souches
CN1194086C (zh) * 2002-02-01 2005-03-23 北京科宇联合干细胞生物技术有限公司 一种神经干细胞制剂的制备方法

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004010959A2 (en) * 2002-07-25 2004-02-05 The Scripps Research Institute Hematopoietic stem cells and methods of treatment of neovascular eye diseases therewith
WO2004098499A2 (en) * 2002-07-25 2004-11-18 The Scripps Research Institute Hematopoietic stem cells and methods of treatment of neovascular eye diseases therewith

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Otani, A. et al. 2002 Nature Medicine, vol. 8, p. 1004-1010 *

Also Published As

Publication number Publication date
ZA200702607B (en) 2008-08-27
KR101309500B1 (ko) 2013-09-24
CA2579292A1 (en) 2006-03-23
AU2005285246A1 (en) 2006-03-23
MX2007002639A (es) 2007-08-06
EP1802199A4 (en) 2008-08-27
EP1802199A2 (en) 2007-07-04
CN101052305B (zh) 2012-10-10
KR20070104512A (ko) 2007-10-26
JP2008512376A (ja) 2008-04-24
CN101052305A (zh) 2007-10-10

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Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired