KR101285645B1 - 진통제 - Google Patents

진통제 Download PDF

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Publication number
KR101285645B1
KR101285645B1 KR1020077011752A KR20077011752A KR101285645B1 KR 101285645 B1 KR101285645 B1 KR 101285645B1 KR 1020077011752 A KR1020077011752 A KR 1020077011752A KR 20077011752 A KR20077011752 A KR 20077011752A KR 101285645 B1 KR101285645 B1 KR 101285645B1
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KR
South Korea
Prior art keywords
pain
carbon atoms
compound
hydrogen
analgesic
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Expired - Fee Related
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KR1020077011752A
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English (en)
Korean (ko)
Other versions
KR20070085436A (ko
Inventor
나오키 이즈미모토
쿠니아키 카와무라
토시카즈 코마가타
타다토시 하시모토
히로시 나가부쿠로
Original Assignee
도레이 카부시키가이샤
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Publication date
Application filed by 도레이 카부시키가이샤 filed Critical 도레이 카부시키가이샤
Publication of KR20070085436A publication Critical patent/KR20070085436A/ko
Application granted granted Critical
Publication of KR101285645B1 publication Critical patent/KR101285645B1/ko
Anticipated expiration legal-status Critical
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
    • C07D489/08—Oxygen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020077011752A 2004-11-04 2005-11-04 진통제 Expired - Fee Related KR101285645B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JPJP-P-2004-00320583 2004-11-04
JP2004320583 2004-11-04
PCT/JP2005/020297 WO2006049248A1 (ja) 2004-11-04 2005-11-04 鎮痛剤

Publications (2)

Publication Number Publication Date
KR20070085436A KR20070085436A (ko) 2007-08-27
KR101285645B1 true KR101285645B1 (ko) 2013-07-12

Family

ID=36319248

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020077011752A Expired - Fee Related KR101285645B1 (ko) 2004-11-04 2005-11-04 진통제

Country Status (12)

Country Link
US (1) US8470845B2 (https=)
EP (1) EP1820505A4 (https=)
JP (1) JP4706636B2 (https=)
KR (1) KR101285645B1 (https=)
CN (1) CN101090722B (https=)
AR (1) AR053098A1 (https=)
CA (1) CA2586181C (https=)
MX (1) MX2007005336A (https=)
NO (1) NO20072832L (https=)
PE (1) PE20060723A1 (https=)
TW (1) TW200621785A (https=)
WO (1) WO2006049248A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2464593T3 (es) * 2005-11-09 2014-06-03 Toray Industries, Inc. Agente terapéutico o profiláctico para trastornos funcionales digestivos
CA2634055C (en) * 2005-12-21 2011-07-05 Toray Industries, Inc. Antitussive agent
FR2902341B1 (fr) 2006-06-16 2011-02-25 Scras Utilisation therapeutique simultanee, separee ou etalee dans le temps d'au moins une neurotoxine botulique, et d'au moins un derive opiace
FR2910327B1 (fr) 2006-12-22 2013-04-26 Scras Utilisation d'au moins une neurotoxine botulique pour traiter la douleur induite par les traitements therapeutiques du virus du sida.
ES2627217T3 (es) * 2007-05-21 2017-07-27 Toray Industries, Inc. Partículas micropulverizadas cristalinas
AU2008254039B2 (en) * 2007-05-21 2013-10-24 Toray Industries, Inc. Method for producing pharmaceutical tablet
US9084817B2 (en) * 2007-05-21 2015-07-21 Toray Industries, Inc. Oral preparation comprising specific organic acid, and method for improvement in elution property and chemical stability of oral preparation
FR2930447B1 (fr) 2008-04-25 2010-07-30 Sod Conseils Rech Applic Utilisation therapeutique d'au moins une neurotoxine botulique dans le traitement de la douleur dans le cas de la neuropathie diabetique
US20210015813A1 (en) 2018-03-08 2021-01-21 Victoria Link Ltd. Treatment of demyelinating diseases

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0066340A1 (en) * 1981-05-25 1982-12-08 Alcoa Nederland B.V. Lamp post having a reinforcement of the aperture in the lower portion
CA2501389A1 (en) 2002-10-09 2004-04-22 Toray Industries, Inc. Remedies or preventives for frequent urination or urinary incontinence and morphinan derivatives having nitrogen-containing heterocyclic group

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4118823B1 (https=) * 1964-02-03 1966-10-31
US3318885A (en) 1965-07-21 1967-05-09 American Cyanamid Co Substituted 6-amino-6, 14-endoethen-ocodides and morphides
KR970011390B1 (ko) * 1992-01-23 1997-07-10 도레이 가부시키가이샤 모르피난 유도체와 약리학적으로 허용되는 이의 산 부가염 및 이를 함유하는 약제학적 조성물
AU686203B2 (en) 1993-07-23 1998-02-05 Toray Industries, Inc. Morphinan derivative and medicinal use
DE69631525T2 (de) 1995-03-03 2004-12-16 Endo Pharmaceuticals Inc. Verwendung von dextromethorphan oder dextrorphan zur behandlung der harninkontinenz
CN1374963A (zh) 1999-07-19 2002-10-16 东丽株式会社 尿频或尿失禁的治疗或预防剂
DE19939044A1 (de) * 1999-08-18 2001-03-15 Gruenenthal Gmbh Verwendung von Morphinanderivaten als Arzneimittel
AU2002227135B2 (en) * 2000-10-31 2008-01-03 Rensselaer Polytechnic Institute 8- substituted-2, 6-methano-3-benzazocines and 3-substituted morphinanes as opioid receptor binding agents
JP4118824B2 (ja) 2004-02-24 2008-07-16 株式会社日立製作所 優先パケットの遅延を最小化するシェーピング装置
JP4118826B2 (ja) 2004-03-01 2008-07-16 リオン株式会社 補聴器用ケースなどの製造方法及びその装置
JP4882744B2 (ja) 2004-03-30 2012-02-22 東レ株式会社 止痒剤

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0066340A1 (en) * 1981-05-25 1982-12-08 Alcoa Nederland B.V. Lamp post having a reinforcement of the aperture in the lower portion
CA2501389A1 (en) 2002-10-09 2004-04-22 Toray Industries, Inc. Remedies or preventives for frequent urination or urinary incontinence and morphinan derivatives having nitrogen-containing heterocyclic group

Also Published As

Publication number Publication date
CA2586181A1 (en) 2006-05-11
JPWO2006049248A1 (ja) 2008-08-07
TWI356826B (https=) 2012-01-21
HK1115808A1 (en) 2008-12-12
JP4706636B2 (ja) 2011-06-22
AR053098A1 (es) 2007-04-25
TW200621785A (en) 2006-07-01
CA2586181C (en) 2012-11-27
US8470845B2 (en) 2013-06-25
PE20060723A1 (es) 2006-08-29
NO20072832L (no) 2007-08-01
EP1820505A4 (en) 2010-01-20
EP1820505A1 (en) 2007-08-22
MX2007005336A (es) 2007-06-25
KR20070085436A (ko) 2007-08-27
CN101090722B (zh) 2011-12-21
WO2006049248A1 (ja) 2006-05-11
CN101090722A (zh) 2007-12-19
US20070299100A1 (en) 2007-12-27

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