KR101280315B1 - Method for manufacturing composition for alleviating atopic dermatitis using phytoncide - Google Patents

Abstract

PURPOSE: A method for manufacturing a phytoncide composition for alleviating atopic dermatitis is provided to penetrate the composition into a dermal layer and to supply nutrients such as phytoncide into skin by pulverizing a complex extract of Pinus koraiensis, Chamaecyparis obtusa, and green tea. CONSTITUTION: A method for manufacturing a phytoncide composition for alleviating atopic dermatitis comprises: a step of dipping Pinus koraiensis and Chamaecyparis obtuse in water for 24-36 hours, drying, pulverizing in a length of 8-10mm, and pulverizing in a length of 3-4mm; a step of pressing the pulverized Pinus koraiensis and Chamaecyparis obtuse and separating a liquid phase; a step of placing the liquid phase for 24 hours and collecting supernatant to obtain a liquid extract; a step of maturing the extract at 13-15 deg. C for 36 hours; a step of soaking green tea leaves in water and pulverizing; a step of maturing the liquid ingredient in a ceramic material reactor at 13-15 deg. C for 36 hours and preparing a liquid extract of green tea; a step of mixing the extracts and injecting to the ceramic material reactor; a step of fermenting at room temperature for 5-6 days and filtering; and a step of maturing the mixture at 26-28 deg. C for 72 hours.

Description

METHOD FOR MANUFACTURING COMPOSITION FOR ALLEVIATING ATOPIC DERMATITIS USING PHYTONCIDE}

The present invention relates to a method for preparing an eczema relief composition suitable for dry skin due to atopy, using a pine / cypress extract and green tea leaves as natural materials. More specifically, the composite extract of pine / cypress extract and green tea extract is prepared into particles smaller than the cell gap of the skin to prepare the composition, so that the composition penetrates deep into the dermal layer of the skin, thereby retaining nutrients such as phytoncite in the skin. Can supply In addition, the composition of the present invention contains a large amount of active ingredients of pine, cypress, green tea leaves can not only protect the skin from bacteria and fungi, but also obtain antioxidant and stimulating effects.

Atopic dermatitis is on the rise globally and is a chronic recurrent skin disease that begins mainly in infancy and childhood. The causes of atopic dermatitis are not clearly identified, but environmental factors, genetic predisposition, immunochemical reactions, and skin barrier abnormalities are considered to be the main causes of atopic dermatitis.

Symptoms of atopic dermatitis are variously manifested as pruritus, dry skin, erythema, redness, eczema, rash or scab. In particular, certain substances or stimuli can easily cause itching and inflammatory reactions, leading to mental stress.

As a drug treatment for atopic dermatitis, topical steroids, topical immunomodulators, systemic steroids, systemic immunosuppressants, antihistamines and the like are usually administered or taken, but these drugs carry risks of various side effects.

Various methods have been developed to improve the symptoms of atopic dermatitis, for example, to remove allergens and enhance the skin barrier function, or to contain the adrenal cortex hormones in external preparations to attenuate allergic reactions and as antibacterial agents. Methods such as preventing secondary infection have been used.

However, most of the cosmetic compositions developed for the purpose of healing atopic dermatitis are derived from chemical components such as surfactants, perfumes, chemical preservatives, and chemical thickeners, and have basic properties despite the fact that they contain various raw materials having effective effects on atopic skin. It has a blind spot that it contains raw materials as an additive. Rather, these problems are likely to lead to the consequences of offsetting the inherent functions of the therapeutically active ingredients. Such methods carry the risk of secondary side effects rather than the underlying cure of the disease.

Therefore, there is a need for a new atopic dermatitis treatment composition having an effect on atopic dermatitis and no side effects, and compositions for treating atopic dermatitis using extracts derived from various natural substances have been developed.

In addition, interest in alternative medical complementary therapies for drug treatment has led to the use of natural materials used as cosmetic ingredients or cosmetic massage products for the treatment of skin diseases. In particular, there have been attempts to develop compositions suitable for atopic skin diseases using aromatherapy.

Specifically, alternative therapies have been used to obtain the healing effects of natural essential oils penetrated into the skin by applying vegetable aroma oils to the skin, as well as to relax the senses through the sense of smell and to stabilize the emotions.

Korean Patent Laid-Open Publication No. 10-2009-0017182 discloses, in particular, atopic dermatitis mitigating agents comprising chamomile oil as an active ingredient.

Republic of Korea Patent No. 10-0597997 discloses a therapeutic agent for atopic skin diseases containing herbs including lavender oil, eucalyptus oil, tea tree oil, carrier oil, baked salt. This application discloses an ointment formulation in which an herbal mixture is taken in the form of an oil and mixed with a carrier oil in an ointment base.

Korean Patent Laid-Open No. 10-2007-0028816 discloses atopy that contains lavender oil, tea tree oil, beeswax or vegetable oil, bamboo salt, surfactant, etc. in a solution obtained by extracting fine powders such as cheonhwa powder, gamguk, white paper, and Angelica from alcohol solution. Dedicated cream compositions and soap compositions are disclosed. In this application, since the herbal medicine material is used by simply mixing the extract extracted from alcohol, there is a disadvantage in that it does not remove the harmful substances contained in the herbal medicine material itself.

Aroma oil is a substance obtained by concentrating several chemicals in the plant several hundred times by distillation extraction method. Because a plant contains a variety of unknown ingredients, the use of high concentrations is limited to achieve some desired efficacy.

As a result of efforts to develop an atopic disease mitigating composition having improved effects and reducing side effects, the present invention has been applied to the skin by applying a plant phytoncide-generating composition to the skin, along with the healing effect of natural essential oils. As a composition capable of obtaining tension relaxation and emotional stabilizing effects, it has been possible to develop an atopic eczema relaxation composition in which phytoncits are generated from natural materials.

The present invention, unlike the conventional drug treatments such as steroids, antihistamines, immunosuppressive agents used in the treatment of atopic dermatitis, atopic dermatitis, which can be safely used for a long period of time, using safe natural ingredients without the risk of side effects, in particular To provide a relief composition for atopic eczema.

As a result of the research efforts of the present inventors to solve the above problems, it has been found that the composition comprising pine and cypress extract and green tea leaves have an excellent stimulating effect on atopic eczema, and phytoncite has a keratinizing effect. .

Specifically, the atopic eczema mitigating composition prepared by the method of the present invention comprises 35 parts by weight of pine tree extract, 25 parts by weight of cypress extract, 5-10 parts by weight of green tea leaf short-term ripening extract, and 5-10 parts by weight of phytoncide ionized water. And 20-25 parts by weight of a cosmetic additive such as glycerin as an additive as a total total content.

As a method of preparing the atopic eczema mitigating composition, first drying the liquid extract extracted from pine and cypress and green tea leaves, pulverizing the dried extract, mixing the phytoncide generation ionized water derived from plant components to the pulverized extract The main raw material is prepared by the step of, and fermenting the resulting mixture. The liquid extract is aged at about 13-15 ° C. for about 36 hours before drying. Thereafter, after mixing all the components, the mixture may be aged at room temperature of 26-28 ° C. for 72 hours to obtain a aged main raw material.

Next, the general cosmetic additives may be mixed with the prepared main raw materials to prepare atopic eczema relief compositions of various cosmetic forms.

In addition, the plant-derived phytoncide generation extract is a liquid substance obtained by aging at room temperature in a water-soluble solvent from the plant material generating the phytoncite.

Pine, cypress, etc. can be used as a plant which produces a phyton cheat.

In addition, the solid materials contained in the main raw material prepared by mixing phytoncide-generated ionized water with pine and cypress trees are pulverized to a size smaller than the skin cell gap. Since the liquid extract primarily extracted from pine and cypress is viscous, it may not penetrate deep into the skin. Accordingly, in the present invention, by using the pulverized extract, which is dried to the first extracted viscous liquid extract, and ground to a size smaller than the skin cell gap, it has the effect of improving the penetration of the composition into the dermal dermal layer.

The aging process is a process of ripening for about 72 hours at room temperature of 26-28 ℃ in a ceramic material reactor through which air and permeate the main raw material mixed with pine extract, cypress extract and phytoncide generated ion water.

The atopic eczema relief composition prepared according to the preparation method of the present invention can be prepared in various forms, for example, as an atopic eczema relief external preparation or skin cleanser of a formulation selected from cream, gel, milk lotion, skin lotion, ointment.

The atopic eczema mitigating composition prepared according to the preparation method of the present invention relieves irritation with excellent moisturizing action in the atopic skin, prevents itching, and prevents the oxidization of keratin and keratinous skin tissues to cure atopic dermatitis. Has a facilitating effect. In addition, the atopic eczema mitigating composition prepared according to the manufacturing method of the present invention is subjected to the short-term aging of each component at low temperature during the manufacturing process, and the long-term aging of the mixture of all the components at room temperature, irritating in the components Phosphorus properties are reduced, and skin-friendly nutrients are thought to be enriched.

The complex composition of pine and cypress extracts, green tea leaves and phytoncite-generated ionized water for a short period of time is effective in improving immunity. Short-term ripening pine and cypress extracts and green tea leaves have been shown to have anti-inflammatory effects. .

Pine tree is an evergreen coniferous tree that grows in the mountains of 100 ~ 1,900m in the whole country.It is native to Korea and is distributed in Japan, China and Siberia. It has good cold-resistance, so it is widely distributed in the high mountains of the mountainous region and has good environmental adaptability, and grows well anywhere in the country. In addition, the pine wood is very beautiful, light and fragrant. In addition, it is easy to process and is used in a variety of applications, pine nuts are used for raw food, pine nuts, milking and other various dishes. In the present invention, the bark and leaves of the pine tree can be easily obtained.

Cypress is a representative species known to produce phytoncites. Phytoncide is known to provide psychological stability, strengthen peripheral blood vessels, strengthen cardiopulmonary function, treat bronchial asthma and pulmonary tuberculosis, and strengthen the heart. It is also known to have pharmacological action to disinfect skin. In the present invention, bark and leaves of the cypress can be used.

Green tea has anti-oxidant effect, anti-aging effect, heavy metal removal effect, anti-diabetic effect, fatty liver prevention, diet effect, anti-allergic effect, detoxification effect of tobacco, bad breath and odor removal effect, tea fragrance component function, alkaline constitution improvement effect, It is known to have various effects such as inflammatory treatment effect, skin beauty effect, immunity enhancement, stress relief, constipation improvement effect, physiological action of caffeine, physiological action of deanine, and radioactive detoxification effect. In the present invention, green tea leaves are used to utilize the anti-inflammatory effects of green tea.

In the present invention, it is preferable to use a complex extract of pine and cypress extract and green tea leaves. The extract obtained by aging this complex extract for 36 hours was shown to have an alleviating effect of atopic dermatitis. How to prepare such an extract is as follows. First, the pine and cypress and green tea leaves are washed and crushed. Each component is aged for about 36 hours at a low temperature of 13-15 ° C. Then, the mixture of all the components is injected into a ceramic-based reactor (aircraft) through which air is permeated and liquid components are not permeated, and then aged at 72-28 ° C. for 72 hours. In this way, the complex extract is separated into a supernatant by short-term aging. The solid / liquid separated composite extract is filtered by a filter to obtain a liquid extract. In the present invention, this liquid extract may be used as it is, or may be used as a ground product which is dried and pulverized. When used as a ground and pulverized powder, it is preferable to use the ground to a size smaller than the skin cell spacing, thereby further improving the penetrating power of the composition penetrating the skin dermis layer.

The reason for using Onggi is that clean purified extracts can be obtained from natural materials by preventing the degeneration of the raw materials, keeping the active substances contained in the raw materials fresh, and allowing the impurities in the raw materials to be filtered naturally. to be.

The atopic eczema mitigating composition of the present invention further contains 5-10 parts by weight of liquid ionized water for generating a phytoncite. The complex extract further contains phytoncide-generating ionized water, which has an excellent antioxidant effect and skin regeneration effect, and keeps the skin clear and refreshed by smoothly supplying nutrients to the skin, thereby exhibiting excellent skin soothing action. With regard to the complex extract component, one major feature of the present invention is the use of green tea leaf extract.

Atopic dermatitis easing agent composition of the present invention contains a total of 60 parts by weight of pine and cypress extract. In the composition of the present invention, the pine and cypress extracts not only have antibacterial and antioxidant effects, but also have excellent moisturizing action to relieve itching and irritation of the skin. The pine and cypress used in the composition of the present invention can be easily obtained from the surroundings as a native plant of Korea.

Pine, cypress and green tea leaves have long been used as folk remedies, and they are known to have an excellent effect on wound healing. Pine and cypress extracts are also used as a very effective treatment for surgical wounds and 2-3 degree burns. .

Such pine, cypress and green tea leaves complex extracts also help the regeneration of aging skin.

In addition, the atopic dermatitis alleviating composition of the present invention may further contain 5-10 parts by weight of phytoncide ionized water. As such, it is thought that the phytoncit generated ionized water in the composition of the present invention will have a synergistic effect in stimulating alleviation and bactericidal action together with the complex extract.

The liquid extracts of pine and cypress are rich in terpene phytoncide, which generates phytoncide by itself, and are rich in vitamins and minerals beneficial to the human body. In addition, the pine wood provides a phytoncite aroma to the final composition to enhance the user's satisfaction. In the present invention, the mixture comprises a phytoncite liquid extract which is recovered by crushing and filtering the pine and cypress extracts.

As a process of obtaining pine and cypress extracts, first, the pine nuts and cypresses collected are soaked in sufficient water for at least one day to be concerned with rosin. The pine and cypress are picked up and dried for one day, and then crushed using a microwaver, for example, an all-rounder. It is preferable to grind | pulverize as a 1st grind | pulverization and a 2nd grind | pulverization. In a 1st grind | pulverization, it grinds to 8-10 mm or less, and in a 2nd grind | pulverization, it grinds to 3-4 mm or less. Then, the crushed pine and cypresses are wrapped and subjected to liquid phase separation with a hydraulic compression press, and the mixture is kept in a standing state for more than 24 hours, and separated into a supernatant and a slurry. The slurry is filtered to separate the supernatant to obtain an extract. have. Further, in addition to the present method, various extraction methods commonly used in the art may be used, and preferably about 1 to 15 times the volume of pine and cypress, which are samples, preferably about 5 to 10 times the water, and the lower level. From about 1 hour at an extraction temperature of 20 to 100 ° C., preferably 50 to 100 ° C. in alcohol or a mixed solvent having a mixing ratio of about 1: 0.1 to 1:10, preferably 1: 1 to 1: 3. 2 days, preferably about 2 hours to 1 day, extracts may be obtained using methods such as cold soaking, hot water extraction, ultrasonic extraction, reflux cooling extraction and the like.

60 parts by weight of the pine and cypress extracts obtained in the first step, 5-10 parts by weight of green tea short-term ripening extract, and 5-10 parts by weight of phytoncide ionized water. The addition amount is 70-75 parts by weight of the pine and cypress extract, the green tea leaf extract and the phytoncite ionized water as a whole, 20-25 parts by weight of additives such as stabilizers, moisturizers.

Preferably, the materials are mixed in a homogenizer at 2500 rpm for about 15 minutes. The pine nuts and cypress extracts and green tea extracts thus mixed are finally aged for 72 hours and aged at room temperature of 26-28 ° C.

In addition, the atopic eczema relaxant composition of the present invention may further contain 5-10 parts by weight of phytoncit ion water derived from a plant component.

As the anion generation and phyton cheat generation number used in the plant component used in the composition of the present invention, the anion generating composition derived from the plant component disclosed in Korean Patent Registration Nos. 10-0715378 and 10-0715396, the applicant of the present invention is used. do. More specifically, the anion-generating alkaline ionized water derived from the plant component is mixed with 40 to 50 parts by weight of leek, 30 to 40 parts by weight of pine needles, 10 to 20 parts by weight of green tea leaves, the mixture is air permeable and the liquid component is permeated It is injected into a ceramic material reactor, which is left untreated at room temperature for 5 to 6 days and then fermented, and then phytoncit generated ionized water is obtained by filtration of the liquid substance produced by the fermentation.

Atopic mitigating compositions prepared using mature fermentation of vegetable complexes release phytoncits that are harmless to the human body. It is combined with harmful oxygen (active oxygen) generated inside the human body and not only discharges it to the outside of the human body, but also has energy to attract various acidic wastes, thereby enhancing the body's natural immunity. It is also known that phytoncit generated water can decompose organic compounds and ozone. Therefore, not only helps to remove various harmful substances stimulating the skin, especially harmful to atopic dermatitis, it will work advantageously to alleviate atopic dermatitis, which is a kind of immune disease by enhancing the body's immunity. The compositions of the present invention are purely natural composite derived materials, generally using 1,3-butylene glycol as a base for formulation, and formulations made with an antiseptic system are stable without any irritation to the skin.

The formulation of the atopic dermatitis alleviating composition of the present invention is not particularly limited. For example, the composition according to the present invention may be used as an external preparation such as milk lotion, skin lotion, ointment, cleaning agent such as soap, or quasi-drug. It is well known in the art to form a composition prepared according to the process of the invention into one of the above formulations.

As the additive of the formulation, a general cosmetic additive may be used, and the composition prepared according to the manufacturing method of the present invention may include, for example, 35 parts by weight of pine tree extract, 25 parts by weight of cypress extract, 5-10 parts by weight of green tea leaf extract. And 5-10 parts by weight of phytoncite ionized water as the main raw material, and 70 to 75 parts by weight of the total composition, and the additive may contain 20 to 25 parts by weight.

Examples of the additive include glycerin (4 parts by weight), xanthan gum (viscosity control agent, 0.5 parts by weight), pentoxyethanol (preservative, 0.4 parts by weight), stearyl alcohol (viscosity control agent, 3.5 parts by weight), Glycerylstearate SE (emulsifying agent, 3.0 parts by weight), caprylic / capric triglyceride (emollient, 3.7 parts by weight), squalane (emolitic, 3 parts by weight), polysorbate 60 (2.0 parts by weight) and Methylparaben (preservative, 2.0 parts by weight) may be contained.

Hereinafter, the specific manufacture example of this invention is demonstrated.

Manufacturing example  One

Pine nuts, cypress and green tea leaves were collected in a clean process to obtain pine and cypress extracts and green tea leaf extracts. The raw materials were washed and pulverized, and each component was short-aged for 36 hours at a low temperature of 13-15 ° C. Next, each component is mixed and injected into a ceramic material reactor through which air is permeated and liquid components are not permeated, and aged for 72 hours at room temperature of 26-28 ° C. to produce a liquid substance, which is then filtered and extracted. Used as. This complex extract is composed of 35 parts by weight of pine extract, 25 parts by weight of cypress extract, and 10 parts by weight of green tea leaf extract.

Green tea leaves were commercially purchased, soaked in water, pulverized and fermented, and the liquid substance produced by the fermentation was filtered and used as an extract.

The bark and cypress were separated and soaked in premise water for 24-36 hours. The pine and cypress were harvested and dried for one day, and then they were first crushed to 8-10 mm using an all-round microwave, which was again crushed to 3-4 mm. The pulverized product was put into a 325 mesh mesh and squeezed with a hydraulic compression press (2HP) to separate liquid phase. The resulting liquid phase was allowed to stand for 24 hours to separate the supernatant from the precipitate (slurry), and the remaining slurry was filtered to take only the supernatant.

60 parts by weight of the pine and cypress extracts prepared above, 5 parts by weight of phytoncide ionized water to 5 parts by weight of green tea leaf extract, and mixed for 60-70 minutes at a speed of 600-650rpm in a homogeneous homogenizer.

After the mixed composition was filtered with a filter, the atopic dermatitis alleviating composition of the present invention was obtained. The pH of the composition was about 6.0-6.5. This composition was used for the test.

Test Example  One

A panel test was conducted on eleven teenagers with atopic dermatitis and five adults in their twenties and thirties with the composition of the present invention for the improvement of atopic dermatitis (Woongjin, Arlesar Cosmetic Research Institute). )

Clinical 1, (adult 20-30s) Before use 66,20 After use 70,35

Clinical 2, (adult 20-30s) Before use 71,35 After use 76,25

Clinical 3, (adults 20-30) Before use 69,00 After use 75,00

4 clinical trials (adult 20-30) 75,21 before use 80,12 after use

Clinical 5, (adult 20-30) Before use 80,11 After use 86,22

Clinical 6, (10) Before use 83,67 After use 88,65

7 clinical trials (10) Before use 76,21 After use 82,54

Clinical 8, (10) Before use 72,31 After use 79,65

Clinical 9, (10) Before use 66.87 After use 75,32

10 clinical trials (10) Before use 82,35 After use 86,36

Clinical 11, (10) Before use 83,25 After use 87,35

Clinical 12, (10) Before use 84,15 After use 86,89

Clinical 13, (10) Before use 85,09 After use 87,19

Clinical 14, (10) Before use 86,10 After use 88,27

Clinical 15, (10) Before use 87,20 After use 89,45

Average 75,42 81,09

As a result of the implementation, the improvement effect is on average from 75,42% to 81,09%.

1.0% by weight of the composition obtained in Preparation Example 1 and 3.0% by weight of 1,3-butylene glycol, 3.0% by weight of glycerin, 4.0% by weight of beeswax, 1.0% by weight of vegetable oil, 10.0% by weight of ethanol of the present invention The product was allowed to be applied to the atopic dermatological lesions of the volunteers three times daily for four weeks and tested for itching, moisturizing and inflammation relief.

Mean of clinical measurements

Items of keratin improvement were surveyed and averaged over 15 points.

Survey Results After 1 day use After 3 days After 1 week use After 2 weeks After 3 weeks After 4 weeks Relieves itching 0.9 1.8 2.9 3 3 3 Moisturizing effect 0.8 1.7 2.1 2.5 2.7 3 Inflammation relief 0.7 1.7 2.1 2.4 2.8 3 Keratin improvement 0.5 1.6 1.9 2.1 2.5 2.9

Points: 3-complete healing, 2-significant healing, 1-slight improvement, 0-no effect

Through the evaluation results, the composition of the present invention showed an excellent itching relief effect within 1 week after use and indicates that the keratin improving action with the rapid inflammation relief progressed quickly.

Examples of formulations of milk lotion and skin lotion prepared according to techniques known in the art using 20-30 parts by weight of the composition according to the present invention are illustrated below.

Example Formulation 1 ( Liquid Skin )

Composition of Example Formulation 1 ingredient weight% Composition prepared in Preparation Example 1 1.0 Butylene glycol 2.0 Propylene glycol 2.0 Carboxyvinyl polymer 0.1 PEG 12 nonylphenyl ether 0.2 Polysorbate 80 0.4 ethanol 10.0 Triethanolamine 0.1 Purified water Up to 100

Example Formulation 2 (Liquid Lotion)

Composition of Example Formulation 2 ingredient weight% Composition prepared in Preparation Example 1 1.0 Wax 4.0 Polysorbate 60 1.5 (emulsifier) Methyl Paraffin 0.5 Capryl / Capryltriglyceride 3,7. (Emolate) glycerin 3.0 (moisturizer) Butylene glycol 3.0 Propylene glycol 3.0 Carboxyvinyl polymer 0.1 Triethanolamine 0.2 100% of compound water Up to 100

Claims (8)

A method for producing a vegetable atopic eczema-releasing composition containing 35 parts by weight of pine tree extract, 25 parts by weight of cypress extract, 5-10 parts by weight of green tea leaf extract and 5-10 parts by weight of phytoncit generated ionized water,
Isolate pine and cypress, soak in 1 to 15 times the volume of pine and cypress for 24 to 36 hours, then scoop it up and dry for a day. Second grinding to 3-4 mm again,
The pine and cypress crushed product was put into a 325 mesh mesh and squeezed with a hydraulic compression press (2HP) to separate liquid phases. Taking only the supernatant to obtain a liquid extract,
First aging of the extract at 13-15 ° C. for 36 hours
Green tea leaves are called in water and pulverized, aged in a ceramic material reactor which is air permeable and liquid components are not permeable at 13-15 ° C. for 36 hours to obtain a liquid extract of the primary aged green tea leaves,
As a step of mixing the extracts and phytoncit generated ionized water, phytoncit generated ionized water is mixed with 40 to 50 parts by weight of leek, 30 to 40 parts by weight of pine needles, 10 to 20 parts by weight of green tea leaves, the mixture is air permeable and liquid components Silver is injected into a non-permeable ceramic material reactor and left to ferment for 5 to 6 days at room temperature, and then using the one obtained by filtering the liquid material produced by fermentation, and
72-hour secondary aging of the mixture at 26-28 ° C. in a ceramic material reactor that only permeates air
≪ / RTI > delete delete delete The method of claim 1, further comprising drying the pine and cypress extracts before mixing with the green tea leaf extract. The method of claim 1 wherein the composition prepared further comprises an additive selected from the group consisting of preservatives, stabilizers, emulsifiers and binders. 7. The method of claim 6, wherein the additive contains 20-25 parts by weight of the composition and comprises glycerin. The method according to claim 1, wherein the prepared composition is used for the preparation of external preparations such as milk lotions, skin lotions, ointments, cleaning agents such as soaps, or quasi-drugs.