KR101196486B1 - Herbal Composition for Treatment of Allergy Diseases - Google Patents

Abstract

The present invention relates to a herbal composition for treating allergic diseases using herbal medicines, based on 100% by weight of the total Chinese medicine composition, 8-12% by weight quince, 8-12% by weight vine root, 4-6% by weight, angle , 4-6% by weight of endodon or mixtures thereof, 4-6% by weight of Ogapi, 4-6% by weight of calendula, 4-6% by weight of low head cavity, mildness, taillight or 24-36% by weight thereof, and By formulating a mixture of powdered, root fluid, pill, ointment, or bath preparation using a mixture of root skins as a residual amount, the internal lymphatic fluid can circulate smoothly through the lymph vessels internally without the side effects of steroids. In addition, by externally smoothing the circulation and respiration of the skin and treating inflammation, allergic diseases can be treated by smoothing the discharge of allergic substances causing the disease.

Description

Herbal Composition for Treatment of Allergic Diseases

The present invention relates to a herbal composition for treating allergic diseases. More specifically, allergic diseases, including rhinitis, asthma, atopy, etc., which means all symptoms appearing in the respiratory system, skin, etc. caused by various substances in nature and chemicals generated in the human environment, using herbal medicines A herbal composition for treatment.

When a disease occurs in the human body, a defense mechanism is activated. The main axis of this defense mechanism is white blood cells. The granulocytes and lymphocytes of the leukocytes are controlled by the human autonomic nervous system consisting of the sympathetic and parasympathetic nerves. Among them, the sympathetic nerve is responsible for the excitement of the body, the parasympathetic nerve stabilizes the body, the diseases occurring in the human body are all associated with the autonomic nerve. For example, when the sympathetic nerve is excited, symptoms such as an increase in heart rate, an increase in blood pressure, sweating, an increase in stress hormones, a change in immune function, and insomnia appear.

On the other hand, when the parasympathetic nerve is properly activated, it feels stable and the vision becomes sensitive to pain, but when the parasympathetic nerve is hyperactive and lymphocytes become excessive, the immune system reacts sensitively to allergic rhinitis, bronchial asthma, Allergic diseases such as atopic dermatitis will occur.

Lymph fluid that flows from capillaries between tissue fluids must collect in the lymph nodes, form lymphatic vessels, merge with venous blood again from the subclavian vein, and enter the heart. Because it is full, it does not flow through the lymphatic vessels and flows tissue fluid, and when it reaches its limit, it flows into the skin. If this phenomenon persists, an oil film is formed throughout the skin, disrupting the circulation of skin tissue and inhibiting skin respiration. The symptoms of this phenomenon are getting worse and worse, the symptoms of the skin's thyroiditis.

When the circulation and breathing of the skin are blocked, it causes the body's autonomous reaction to itch and scratches the blocked area to try to breathe through it, and the mechanism to circulate by supplying excessive blood flow into the capillaries of the skin works. Skin redness; In other words, itching, redness and inflammatory condition of the afflicted skin of atopic patients, which is a kind of allergic disease, is a healing response as a physiological response to normalize the human body.

The recent increase in allergic diseases compared to the past may be due to environmental factors such as air pollution, water quality, and soil pollution, although there may be mental factors including historical factors and stress.

As a treatment for atopic dermatitis, a type of allergic disease, various drugs such as antihistamines, antiserotonin agents, anti-leukotrienes, anti-inflammatory drugs, and steroid hormones are prescribed. These are all symptomatic treatments. However, it does not fundamentally cure atopic dermatitis. These drugs develop more severe symptoms when the drug is discontinued than before the accumulated harmful substances were released.

As a result, more severe symptomatic therapy cannot be forced due to severe symptoms that cannot be tolerated, and this vicious cycle continues to be repeated to escape symptomatic therapy. While symptomatic therapy does not cause significant dependence in the short term, it does not cause much damage, but if it lasts for several years, it becomes difficult to escape the disease.

In particular, steroids are substances with a cholesterol backbone and do not release well and remain easily in the tissues. Ointments containing it can be severely deposited on the skin, causing new cholesterol oxidative dermatitis, which leads to purulent inflammation, which requires stronger steroids to prevent the inflammation. Gradually fall into steroid dependence, in the end, even if you try to get away from the effects of steroids, the repulsion phenomenon is so strong that it is forced to continue to depend on steroids.

Other side effects of steroids include cataracts, glaucoma, inhibition of bone growth, decreased immunity of the body, and steroid dermatosis.If steroids are used externally, inhaled or orally for a long time, the routine rhythm is broken and sleepy during the day and sleep at night. You may notice steroid psychosis, which begins to appear and you feel nervous and anxious and eventually end up in a relaxed daily life.

In general, the oriental medicine view or method of treating atopy is recognized as a disease caused by the birth of a young child with innate tan fever and the heat of the blood caused by food or stress during his or her life. Therefore, the treatment method is to avoid mental and physical stress as usual, stable, and as a method for removing the heat in the blood, cupping to remove the poison of the skin, or to shed heat poison generated on the skin It is due to the fact that it is caused by the release of toxins in the body as an active antiperspirant, or by the epidermis caused by the heat poison generated inside the human body, and caused by diarrhea with a cold medicine or by dryness and itching due to heat. It is recognized that it is moisturizing and treatment. This too is not a fundamental treatment based on the cause.

As an example of treating allergic diseases using herbal medicines, Korean Patent Laid-Open Publication No. 2002-7806 discloses an allergy and / or asthma prophylactic and therapeutic composition comprising herbal extracts, and an effective amount of neck skin and Prickly Pear Extract is used.

In addition, Korean Patent Publication No. 2006-104409 discloses a herbal composition for the treatment of atopic dermatitis, and it is made of Hwapi, Saenghwanghwang, Hyunsam, Donkey, Gyeji, Creation, Ephedra, Root, Hyeonggae, Windproof, Sesin, Cheonoh, Choo, Cheonggung, It is composed to contain Chinese herbal medicine composite consisting of licorice, sewage and sungwoongsul.

The conventional herbal composition for treating atopic dermatitis has a problem in that it is not possible to cure inflammation and hypertrophy of lymph nodes, which is a basic cause of clogging of the lymphatic circulation system of allergic diseases, and thus cannot fundamentally cure allergic diseases such as rhinitis, asthma and atopy.

The purpose of the present invention is to treat inflammation and hypertrophy of the lymph nodes, which is the basic cause of the lymph circulation system of allergic diseases by using a specific herbal medicine to have a specific composition ratio so that the lymph fluid circulates smoothly through the lymphatic vessel, such as rhinitis, asthma, atopy, etc. Recognizing that it is possible to fundamentally treat allergic diseases, to provide a herbal composition that can cure the internal causes of allergic diseases by treating the internal causes of allergic diseases without having side effects and the like.

Herbal medicine composition for treatment of allergic diseases of the present invention for achieving the above object, 8-12% by weight of quince, 8-12% by weight of grape root, 4-6% by weight, angle of the total 100% by weight of the herbal composition , 4-6% by weight of endodon or mixtures thereof, 4-6% by weight of Ogapi, 4-6% by weight of calendula, 4-6% by weight of low head cavity, mildness, taillight or 24-36% by weight thereof, and It is produced by extracting or pulverizing a mixture of roots and skins as the remaining amount.

Of the present invention, in the amount of 8-12% by weight and 16-24% by weight of the tailings, the tailings or the tailings or the mixture thereof, 24-36% by weight are mixed.

The mixture of the present invention is prepared by hot water extraction as water.

The herbal composition of the present invention is to have a formulation of powder, lactose, pill, ointment or bath preparation.

The powder of the present invention, the first step of hot water in 60-80% by weight of 100% by weight of the herbal medicine powder obtained by pulverizing the mixed herbal medicine mixture having a composition ratio of claim 1 for 8 to 10 hours; A second step of stirring and kneading for 8 to 10 hours after adding the remaining amount of the herbal medicine powder to the bath liquid of the first step; And it is prepared by the third step of drying the drug of the second step to prepare a powder form.

According to the present invention, by mixing a specific herbal medicine in a specific composition ratio to prepare a formulation such as powder, lactose, pill, ointment, bathing agent, etc., internal body lymph fluid without internal side effects without steroids, etc. It smoothly circulates through the lymphatic vessels and externally directly removes the lymphatic membranes spread throughout the skin to facilitate circulation and respiration of the skin and to treat inflammation, thereby preventing the release of allergens that cause these diseases. It can be used to treat allergic diseases such as rhinitis, asthma and atopy.

Hereinafter, preferred embodiments of the present invention will be described. The following examples are intended to illustrate the invention and do not limit the scope of the invention.

Herbal medicine composition for treatment of allergic diseases according to the present invention, 8-12% by weight of quince, 8-12% by weight of grape root, 4-6% by weight of root root, endodon, endodon or mixture thereof 4-6% by weight, 4-6% by weight of ogapi, 4-6% by weight of calendula, 4-6% by weight of low head cavity, mifudo, taillight or mixtures thereof 24-36% by weight It is characterized in that it is prepared by extraction or grinding.

The Chinese quince (木瓜) is the fruit of the Chinese quince, promotes the secretion of digestive enzymes to improve digestion and make tea or drink alcohol. It is a warm, tasteful and nontoxic medicine, which controls the cessation of cessation of the roots of the gyran, and digests the plant, stops the thirst of Lihu, Regulates cattle, nausea and mud, strengthens the musculature, and heals the power of the legs and knees.

In addition, it gains muscle and blood blast furnace entering the liver. Enter the limbs of the limbs to protect the lungs, remove moisture, harmonize the stomach and nourish the rain. The Chinese quince is used in the range of 8 to 12% by weight relative to the total 100% by weight of the herbal composition according to the present invention. Outside this range, the effect of treating allergic diseases is minimal.

Grape root (葡萄 根) is the root of the vine, it is effective to drive off the sand breeze (風邪), eliminate the wet sand (濕 邪) and urine out well. It is flat and tastes sweet and nontoxic. Changjin rules over the uncured. The castle is able to descend and to swallow up.

The grape root is used in the range of 8 to 12% by weight relative to the total 100% by weight of the herbal composition according to the present invention. Outside this range, the effect of treating allergic diseases is minimal.

In the above, the root root (蘆 根) is a reed root, when the ear is not yet reed is called the root root. It is cold in nature, sweet in taste and nontoxic. It governs Sogal and sputum, and opens the stomach to rule the deep heat and regal of maternal and pregnant women. The root is used in the range of 4 to 6% by weight relative to the total 100% by weight of the herbal composition according to the present invention. Outside this range, the effect of treating allergic diseases is minimal.

In the above, the cherry tree is an cherry tree, and the cherry tree is a fruit ripened in June in red and sweet and sour taste. It is warm in nature, sweet in taste and nontoxic. Chojungikbi (調 中 益脾) and make the face light.

The endo, endo meat or mixtures thereof are used in the range of 4 to 6% by weight relative to the total 100% by weight of the herbal composition according to the present invention. Outside this range, the effect of treating allergic diseases is minimal.

Ogapi (五加皮) is the bark of the roots, stems and branches of the tree, the nature is warm, taste is spicy and bitter, there is no toxicity. Ono, seven statues, ripen, harden the bones, strengthen the limbs, control the man's genitals and the woman's yin and yang, and heal the lumbar pain .

The agapi is used in the range of 4 to 6% by weight relative to the total 100% by weight of the herbal composition according to the present invention. Outside this range, the effect of treating allergic diseases is minimal.

Songhwa (松花) refers to the pollen of pine trees, characterized by a light yellow and sweet scent. Its properties are warm, flat and nontoxic. Relax the five intestines, reduce heat, heal all spears, heads, and cultivation and remove fraud.

The calendula is used in the range of 4 to 6% by weight relative to the total 100% by weight of the herbal composition according to the present invention. Outside this range, the effect of treating allergic diseases is minimal.

In the above, low-duty gang (also called `` mi-gang '') is a collection of rice bran and brown rice oil stuck to the ball of a lanyard when the rice bran is separated by putting the hell on a treadmill. Cure the blockage.

The low head cavity is used in the range of 4 to 6% by weight relative to the total 100% by weight of the herbal composition according to the present invention. Outside this range, the effect of treating allergic diseases is minimal.

In the above, Mifudo is the fruit of the persimmon tree dried in the sun, Mifu lantern is the stem (vine) of the perennial tree, and the azalea grows in the deep valleys of the country as one of the representative wild fruits together with the wild flowers. It is a round fruit about the size of a finger. Its color is blue and its sweetness is strong. It ripens in September ~ October. It is cold, sweet and sour and nontoxic. Severe thirst and burns to treat stone forests (石淋), to cool the stomach (脾胃) and to block the heat symptoms and reversal (().

The microfibers, microfluidic lights or mixtures thereof are used in the range of 24 to 36% by weight relative to the total 100% by weight of the herbal composition according to the present invention. Outside this range, the effect of treating allergic diseases is minimal. More preferably, a mixture is used in which the microporousity is mixed in an amount of 8-12% by weight and the taillight in an amount of 16-24% by weight.

The roots of Yugeun-pi (楡 根 皮) is the bark of the elm, flat nature, sweet taste and non-toxic. His temper is so conspicuous that heales the urinary tract of stool, and removes Isu-do, which helps the way of urine to go out, and the ileum of the gut. , Edema (浮腫) and swelling (五淋; five kinds of gonorrhea from the oriental medicine) is beneficial, heals insomnia and stool problems.

The roots of the roots of the Chinese medicinal composition according to the invention 100% by weight of the Chinese quince; Grape root; Labor; Endodon, endodon or mixtures thereof; Ogapi; Calendula; Low head cavity; It is used in remaining amount except microfudo, microfuter or mixture thereof. Outside this range, the effect of treating allergic diseases is minimal. It is preferably used in an amount of 20-30% by weight relative to the total 100% by weight of the herbal composition.

Chinese quince as raw material used for the preparation of extracts or ground products; Grape root; Labor; Endodon, endodon or mixtures thereof; Ogapi; Calendula; Low head cavity; Mifudo, Mifu etc. or mixtures thereof; And yugeunpi may be used without limitation, if purchased commercially.

In an embodiment of the present invention, the Chinese quince which is used as a component of the composition according to the present invention; Grape root; Labor; Endodon, endodon or mixtures thereof; Ogapi; Calendula; Low head cavity; Mifudo, Mifu etc. or mixtures thereof; Although herbal extracts of Yu-Geun-pi may be prepared by hot water extraction, any conventional extraction method used in the art, for example, alcohol extraction, hot water extraction, organic solvent extraction, supercritical extraction, etc. may be used without limitation.

In the embodiment of the present invention, 5 to 7 times of water was mixed with respect to the total weight of the herbal medicine of the present invention was heated and concentrated according to a conventional method to obtain an extract of approximately four times the weight of herbal medicine. However, the extract preparation process is not limited to this range and can be carried out without limitation as long as it is a conventional herbal medicine extraction method.

In addition, the herbal composition of the present invention may have a formulation such as powder, lactose, pill, beverage and the like. In addition, it may have a formulation such as ointment, bath preparations that can be applied to the skin without oral administration.

In the present invention, the powder may be prepared according to a conventional method, but 60-80% by weight of 100% by weight of the herbal medicine powder obtained by pulverizing the mixed herbal medicine mixture having the above composition ratio for 8 to 10 hours according to a conventional method. A first step of boiling water; A second step of stirring and kneading the remaining amount of the herbal medicine powder in the first step of the bath liquid for 8 to 10 hours according to a conventional method; And it may be prepared by the third step of preparing the drug of the second step in a powder form by drying in a thin piece according to a conventional method. In particular, by passing through the kneading process in the second step, the water-soluble and fat-soluble components of the herbal ingredients can be extracted.

Example  One - Of hot-water extract  Produce

[Preparation of Herbal Medicines]

10% by weight of quince, 10% by weight of vine root, 5% by weight of root root, 5% by weight of endodon meat, 5% by weight of ogapi, 5% by weight of calendula, 5% by weight of low head cavity, and 10% by weight of mildew 1,600 g of the herbal mixture was prepared in an amount of 20% by weight, taillight, and 25% by weight of root skin.

[Hot Water Extraction]

1,600 g of the medicinal herb mixture and 9.0 L of water were mixed and heated and concentrated for 4 hours and 30 minutes according to a conventional discharging method to obtain 6.3 L of the medicinal herb extract. 45 packs were prepared in an amount of 140 ml / pack. This process was repeated several dozen times to produce a large amount of the same pack.

Example  2 - Sanje  Produce

[Preparation and Crushing of Herbal Medicine]

The herbal mixture having the composition ratio of Example 1 was washed, dried and then ground in a conventional manner to prepare a herbal mixture powder.

[Water bath, stirring, kneading and drying]

About 70% by weight of the total 100% by weight of the prepared herbal mixture powder was subjected to a bath while wearing water for 9 hours according to a conventional method. Thereafter, the remaining amount of 30% by weight of the herbal medicine powder was added to the drug, and then the soaking and kneading process were performed for 9 hours according to a conventional method. The finished drug was dried for 8 hours in a thinly sliced state using a rolling machine according to a conventional method to prepare a powder in powder form.

Test Example  One - Of hot-water extract  Allergic disease treatment effect examination

(1) 47 children and adult patients with allergic rhinitis, (2) 40 children and adult patients with allergic dermatitis, (3) 25 children and adult patients with allergic asthma, (4) 32 children and adult patients identified as eczema, (5) 25 children and adults identified as pollen allergy, and (6) 30 children and adult patients identified as atopic dermatitis (15 each) It was set as.

140 ml / pack of the hot water extract of Example 1 was taken three times a day during the administration period of Table 1, and then the state change was observed, and the results are shown in Table 1 below.

division
Number of experimenters Dosage period (1 ~ 3 months) Dosage period (3-6 months) Number of respondents Reaction Rate Number of respondents Reaction Rate Allergic rhinitis 47 people 42 people improved 89% 42 people cured 89% Allergic dermatitis 40 persons 32 people improved 80% 32 people cured 80% Allergic asthma 25 persons 18 people improved 72% 25 people cured 100% eczema 32 persons 0 people 0 % 32 people cured 100% pollen allergy 25 persons 0 people 0 % 25 people cured 100% Atopic dermatitis 30 persons 17 people improved 57% 26 people improved 87%
However, improvement was the case of reduced to 50-20% of the initial symptoms, cure is less than 20% of the initial symptoms.

As can be seen in Table 1, the herbal composition of the present invention obtained as an extract showed a high response to a variety of allergic diseases even when taking 1-3 months, cure or even a higher response to long-term administration. Specifically, for allergic rhinitis, runny nose, stuffy nose, itching; Urticaria, itching in case of allergic dermatitis; Bronchial inflammation, cough, dyspnea in case of allergic asthma; Itching, blisters, rash in the case of eczema; Eye, nose itching, sneezing, runny nose in case of pollen allergy; In case of atopic dermatitis, symptoms such as dry skin, itching, and rash were cured or improved.

Test Example  2 - Sanje  Allergic disease treatment effect examination

(1) 40 children and adult patients with allergic rhinitis, (2) 40 children and adult patients with allergic dermatitis, (3) 25 children and adult patients with allergic asthma, (4) 32 children and adult patients identified as eczema, (5) 25 children and adults identified as pollen allergy, and (6) 30 children and adult patients identified as atopic dermatitis (15 each) It was set as.

After taking the powder of Example 2 at a dose of 3 g / time 3 times a day for the administration period of Table 2, the state change was observed, and the results are shown in Table 2 below.

division
Number of experimenters Dosage period (1 ~ 3 months) Dosage period (3-6 months) Number of respondents Reaction Rate Number of respondents Reaction Rate Allergic rhinitis 40 persons 36 people improved 90% 36 people cured 90% Allergic dermatitis 40 persons 32 people improved 80% 32 people cured 80% Allergic asthma 25 persons 18 people improved 72% 25 people cured 100% eczema 32 persons 0 people 0 % 32 people cured 100% pollen allergy 25 persons 0 people 0 % 25 people cured 100% Atopic dermatitis 30 persons 16 people improved 53% 25 people improved 83%
However, improvement was the case of reduced to 50-20% of the initial symptoms, cure is less than 20% of the initial symptoms.

As can be seen in Table 2, the herbal composition of the present invention having a powder formulation showed a high improvement in allergic diseases even when administered for 1-3 months, and cure or higher response when taken for a long time. Seemed.

The present invention described above can be embodied in many other forms without departing from the spirit or main features thereof. Therefore, the above embodiments are merely examples in all respects and should not be interpreted limitedly.

Claims (5)

8-12% by weight of quince, 8-12% by weight of grape root, 4-6% by weight of root root, 4-6% by weight of endodon, endodon or mixture thereof, 4-6% by weight of Ogapi based on 100% by weight of the herbal composition Herbal medicine for the treatment of allergic diseases prepared by extracting or pulverizing 4-6% by weight, 4-6% by weight of the lower head cavity, 4-6% by weight, mildly, poorly, or mixtures thereof, and 24-36% by weight of these mixtures. Composition. The method of claim 1,
Herbal medicine composition for the treatment of allergic diseases, characterized in that the mixture is in the amount of 8-12% by weight, 16-24% by weight of the tailings in the 24-36% by weight of the tailings, taillights or mixtures thereof. The method of claim 1,
The mixture is a herbal composition for treating allergic diseases, characterized in that prepared by hot water extraction as water. The method of claim 1,
The herbal composition is a herbal composition for treating allergic diseases, characterized in that it has a formulation of powder, lactose, pill, ointment or bath preparation. 5. The method of claim 4,
The powder, the first step of hot water 60-80% by weight in 100% by weight of the herbal medicine powder obtained by grinding the mixed herbal medicine mixture to have a composition ratio of claim 1 for 8 to 10 hours; A second step of stirring and kneading for 8 to 10 hours after adding the remaining amount of the herbal medicine powder to the bath liquid of the first step; And a third step of drying the drug of the second step to prepare the powder in the form of powder.