KR101158603B1 - 비강용 스프레이를 전달하는 방법 - Google Patents

비강용 스프레이를 전달하는 방법 Download PDF

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Publication number
KR101158603B1
KR101158603B1 KR1020077014446A KR20077014446A KR101158603B1 KR 101158603 B1 KR101158603 B1 KR 101158603B1 KR 1020077014446 A KR1020077014446 A KR 1020077014446A KR 20077014446 A KR20077014446 A KR 20077014446A KR 101158603 B1 KR101158603 B1 KR 101158603B1
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KR
South Korea
Prior art keywords
spray
olopatadine
formulation
nasal
delete delete
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
KR1020077014446A
Other languages
English (en)
Korean (ko)
Other versions
KR20070086638A (ko
Inventor
게랄드 카글
지. 마이클 왈
Original Assignee
알콘, 인코퍼레이티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by 알콘, 인코퍼레이티드 filed Critical 알콘, 인코퍼레이티드
Publication of KR20070086638A publication Critical patent/KR20070086638A/ko
Application granted granted Critical
Publication of KR101158603B1 publication Critical patent/KR101158603B1/ko
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L9/00—Disinfection, sterilisation or deodorisation of air
    • A61L9/015—Disinfection, sterilisation or deodorisation of air using gaseous or vaporous substances, e.g. ozone
    • A61L9/04—Disinfection, sterilisation or deodorisation of air using gaseous or vaporous substances, e.g. ozone using substances evaporated in the air without heating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/006—Sprayers or atomisers specially adapted for therapeutic purposes operated by applying mechanical pressure to the liquid to be sprayed or atomised
    • A61M11/007—Syringe-type or piston-type sprayers or atomisers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A61M15/0025—Mouthpieces therefor with caps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/08—Inhaling devices inserted into the nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/10—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mechanical Engineering (AREA)
  • Inorganic Chemistry (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
KR1020077014446A 2004-11-24 2005-10-31 비강용 스프레이를 전달하는 방법 Expired - Lifetime KR101158603B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US63088604P 2004-11-24 2004-11-24
US60/630,886 2004-11-24
PCT/US2005/039268 WO2006057769A2 (en) 2004-11-24 2005-10-31 Method of delivering nasal spray

Publications (2)

Publication Number Publication Date
KR20070086638A KR20070086638A (ko) 2007-08-27
KR101158603B1 true KR101158603B1 (ko) 2012-07-09

Family

ID=36498400

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020077014446A Expired - Lifetime KR101158603B1 (ko) 2004-11-24 2005-10-31 비강용 스프레이를 전달하는 방법

Country Status (19)

Country Link
US (3) US20060110328A1 (enExample)
EP (1) EP1814538B1 (enExample)
JP (1) JP5068172B2 (enExample)
KR (1) KR101158603B1 (enExample)
CN (2) CN101065122A (enExample)
AT (1) ATE443516T1 (enExample)
AU (1) AU2005309951B2 (enExample)
BR (1) BRPI0518283A2 (enExample)
CA (1) CA2586553C (enExample)
CY (1) CY1110528T1 (enExample)
DE (1) DE602005016833D1 (enExample)
DK (1) DK1814538T3 (enExample)
ES (1) ES2331619T3 (enExample)
MX (1) MX2007005845A (enExample)
PL (1) PL1814538T3 (enExample)
PT (1) PT1814538E (enExample)
SI (1) SI1814538T1 (enExample)
WO (1) WO2006057769A2 (enExample)
ZA (1) ZA200704139B (enExample)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6788460B2 (en) 1998-04-15 2004-09-07 Duke University Projection screen apparatus
US6829087B2 (en) 1998-04-15 2004-12-07 Bright View Technologies, Inc. Micro-lens array based light transmitting screen with tunable gain
US6816306B2 (en) 1998-04-15 2004-11-09 Bright View Technologies Inc. Micro-lens array based light transmitting screen with high resolution and low imaging artifacts
US7977376B2 (en) * 2001-06-27 2011-07-12 Novartis Ag Olopatadine formulations for topical nasal administration
WO2008097220A1 (en) 2007-02-07 2008-08-14 Alcon, Inc. Olopatadine formulations for topical nasal administration
BR112012001169A2 (pt) 2009-07-17 2016-03-01 Alcon Res Ltd sistema de pulverização nasal de olopatadina para crianças
WO2011027322A1 (en) 2009-09-03 2011-03-10 Ranbaxy Laboratories Limited Extended release dosage form containing olopatadine for oral administration
GB2485604A (en) * 2010-11-22 2012-05-23 Martin Chard Device for marking a surface
UA116793C2 (uk) 2013-09-13 2018-05-10 Гленмарк Спешіалті С.А. Стабільна фармацевтична композиція з фіксованою дозою, що містить мометазон й олопатадин
US9370483B2 (en) 2013-09-13 2016-06-21 Glenmark Specialty S.A. Stable fixed dose pharmaceutical composition comprising mometasone and olopatadine
US9937189B2 (en) * 2013-09-13 2018-04-10 Glenmark Specialty S.A. Stable fixed dose pharmaceutical composition comprising mometasone and olopatadine
US10548907B2 (en) 2013-10-04 2020-02-04 Glenmark Specialty S.A. Treatment of allergic rhinitis using a combination of mometasone and olopatadine
US10758550B2 (en) 2013-10-04 2020-09-01 Glenmark Specialty S.A. Treatment of allergic rhinitis using a combination of mometasone and olopatadine
US10653661B2 (en) 2013-10-04 2020-05-19 Glenmark Specialty S.A. Treatment of allergic rhinitis using a combination of mometasone and olopatadine
MX2015009429A (es) 2013-10-04 2015-10-09 Glenmark Pharmaceuticals Ltd Tratamiento de rinitis alergica utilizando una combinacion de mometasona y olopatadina.
US10016443B2 (en) 2013-10-04 2018-07-10 Glenmark Specialty S.A. Treatment of allergic rhinitis using a combination of mometasone and olopatadine
CN104063850B (zh) * 2014-06-24 2017-02-01 广东互维科技有限公司 红眼修复方法
US11679210B2 (en) 2014-10-03 2023-06-20 Glenmark Specialty S.A. Dispensing device and pharmaceutical composition for the treatment of rhinitis
CN107569454B (zh) * 2017-09-29 2018-05-04 深圳大佛药业股份有限公司 一种盐酸奥洛他定鼻喷雾剂及其制备方法
US12303635B2 (en) 2018-04-16 2025-05-20 Glenmark Specialty S.A. Dispensing device and pharmaceutical composition for the treatment of rhinitis
US11890409B1 (en) * 2019-11-19 2024-02-06 Saeed Rezakhany Methods of curing early stages of, and preventing, upper respiratory infections and applicators therefor
USD969992S1 (en) * 2020-12-23 2022-11-15 Aptar France Sas Device for nasal spray
JP2025506999A (ja) * 2022-03-02 2025-03-13 ヴィジャイ ドュッガル 粘膜の保護および治療のための過酸化水素ベースの治療用スプレー仮出願への相互参照 本出願は、2022年3月に出願された米国仮出願第633109710号の利益を受けるものである。

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE555319A (enExample) * 1956-03-21 1900-01-01
GB8520662D0 (en) * 1985-08-17 1985-09-25 Wellcome Found Tricyclic aromatic compounds
US4923892A (en) * 1985-08-17 1990-05-08 Burroughs Wellcome Co. Tricyclic aromatic compounds
JPS6310784A (ja) * 1986-03-03 1988-01-18 Kyowa Hakko Kogyo Co Ltd 抗アレルギー剤
PH24976A (en) * 1987-08-13 1990-12-26 Glaxo Group Ltd Indole derivatives
JPH0323237U (enExample) * 1989-07-19 1991-03-11
US5641805A (en) * 1995-06-06 1997-06-24 Alcon Laboratories, Inc. Topical ophthalmic formulations for treating allergic eye diseases
US5976573A (en) * 1996-07-03 1999-11-02 Rorer Pharmaceutical Products Inc. Aqueous-based pharmaceutical composition
FR2803612B1 (fr) * 2000-01-12 2002-12-06 Michel Jean Louis Mar Doustaly Point d'eau sanitaire adaptable a une cuvette de wc
GB0014892D0 (en) * 2000-06-16 2000-08-09 Glaxo Group Ltd Novel pharmaceutical formulation
IT1317998B1 (it) * 2000-06-26 2003-07-21 Medical Internat Licensing N V Valvola erogatrice per spray nasale.
TWI231759B (en) * 2001-06-27 2005-05-01 Alcon Inc Olopatadine formulations for topical administration
EP1426059A4 (en) * 2001-09-14 2007-01-17 Ono Pharmaceutical Co DRUGS FOR TREATING PRURIT
CA2504200A1 (en) * 2002-11-12 2004-05-27 Alcon, Inc. The use of an anti-allergy agent and a steroid to treat allergic rhinitis
US7812120B2 (en) * 2003-03-21 2010-10-12 Par Pharmaceutical, Inc. Nasal calcitonin formulations containing chlorobutanol

Also Published As

Publication number Publication date
SI1814538T1 (sl) 2010-01-29
US20140227326A1 (en) 2014-08-14
ATE443516T1 (de) 2009-10-15
AU2005309951A1 (en) 2006-06-01
DE602005016833D1 (de) 2009-11-05
CA2586553A1 (en) 2006-06-01
US20170172974A1 (en) 2017-06-22
CN103860540A (zh) 2014-06-18
KR20070086638A (ko) 2007-08-27
CY1110528T1 (el) 2015-04-29
US20060110328A1 (en) 2006-05-25
MX2007005845A (es) 2007-07-04
EP1814538A2 (en) 2007-08-08
BRPI0518283A2 (pt) 2008-11-11
EP1814538B1 (en) 2009-09-23
WO2006057769A3 (en) 2006-08-31
WO2006057769A2 (en) 2006-06-01
CN101065122A (zh) 2007-10-31
ZA200704139B (en) 2008-10-29
PL1814538T3 (pl) 2010-02-26
DK1814538T3 (da) 2009-11-02
CA2586553C (en) 2015-02-10
EP1814538A4 (en) 2007-11-07
PT1814538E (pt) 2009-11-10
JP2008521488A (ja) 2008-06-26
ES2331619T3 (es) 2010-01-11
JP5068172B2 (ja) 2012-11-07
AU2005309951B2 (en) 2011-07-07

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