KR101086095B1 - 분무용 시클레소니드의 수성 현탁액 - Google Patents

분무용 시클레소니드의 수성 현탁액 Download PDF

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Publication number
KR101086095B1
KR101086095B1 KR1020067013760A KR20067013760A KR101086095B1 KR 101086095 B1 KR101086095 B1 KR 101086095B1 KR 1020067013760 A KR1020067013760 A KR 1020067013760A KR 20067013760 A KR20067013760 A KR 20067013760A KR 101086095 B1 KR101086095 B1 KR 101086095B1
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KR
South Korea
Prior art keywords
ciclesonide
delete delete
suspension
mixtures
autoclaving
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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KR1020067013760A
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English (en)
Korean (ko)
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KR20060122890A (ko
Inventor
안트예 브뤽-셰플러
Original Assignee
니코메드 게엠베하
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34684543&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR101086095(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 니코메드 게엠베하 filed Critical 니코메드 게엠베하
Publication of KR20060122890A publication Critical patent/KR20060122890A/ko
Application granted granted Critical
Publication of KR101086095B1 publication Critical patent/KR101086095B1/ko
Assigned to 다케다 게엠베하 reassignment 다케다 게엠베하 권리의 전부이전등록 Assignors: 다케다 게엠베하
Assigned to 아스트라제네카 아베 reassignment 아스트라제네카 아베 권리의 전부이전등록 Assignors: 다케다 게엠베하
Assigned to 코비스 파마 비.브이. reassignment 코비스 파마 비.브이. 권리의 전부이전등록 Assignors: 아스트라제네카 아베
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
KR1020067013760A 2003-12-16 2004-12-15 분무용 시클레소니드의 수성 현탁액 Expired - Lifetime KR101086095B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP03028848.4 2003-12-16
EP03028848 2003-12-16
PCT/EP2004/053495 WO2005058935A2 (en) 2003-12-16 2004-12-15 Aqueous suspensions of ciclesonide for nebulisation

Publications (2)

Publication Number Publication Date
KR20060122890A KR20060122890A (ko) 2006-11-30
KR101086095B1 true KR101086095B1 (ko) 2011-11-25

Family

ID=34684543

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020067013760A Expired - Lifetime KR101086095B1 (ko) 2003-12-16 2004-12-15 분무용 시클레소니드의 수성 현탁액

Country Status (21)

Country Link
US (2) US20070117783A1 (https=)
EP (2) EP2319858B1 (https=)
JP (1) JP5001657B2 (https=)
KR (1) KR101086095B1 (https=)
CN (1) CN100513417C (https=)
AR (1) AR046892A1 (https=)
AU (1) AU2004298447B2 (https=)
BR (1) BRPI0416854B8 (https=)
CA (1) CA2549038C (https=)
CO (1) CO5700832A2 (https=)
EA (1) EA012388B1 (https=)
EC (1) ECSP066608A (https=)
IL (1) IL175461A (https=)
MY (1) MY159377A (https=)
NO (1) NO337225B1 (https=)
NZ (1) NZ547217A (https=)
PE (1) PE20050941A1 (https=)
TW (1) TWI350757B (https=)
UA (1) UA87123C2 (https=)
WO (1) WO2005058935A2 (https=)
ZA (1) ZA200603768B (https=)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2022796A1 (en) * 2007-08-07 2009-02-11 Nycomed GmbH Amorphous ciclesonide
US7984792B2 (en) * 2008-03-03 2011-07-26 Rolls-Royce Corporation Lubrication system
WO2010064522A1 (ja) * 2008-12-03 2010-06-10 株式会社Ｌｔｔバイオファーマ 修飾型スーパーオキサイドジスムターゼ含有吸入剤
CA3004707C (en) 2009-09-02 2022-05-31 Synedgen Inc. Methods and compositions for disrupting biofilm utilizing chitosan-derivative compounds
US10105356B2 (en) 2011-01-31 2018-10-23 Avalyn Pharma Inc. Aerosol pirfenidone and pyridone analog compounds and uses thereof
WO2012106382A1 (en) 2011-01-31 2012-08-09 Genoa Pharmaceuticals, Inc. Aerosol pirfenidone and pyridone analog compounds and uses thereof
WO2013024036A1 (en) 2011-08-12 2013-02-21 Boehringer Ingelheim Vetmedica Gmbh Funny current (if) inhibitors for use in a method of treating and preventing heart failure in feline
US11007150B2 (en) 2011-08-18 2021-05-18 Covis Pharma Gmbh Pharmaceutical aerosol product for administration by oral or nasal inhalation
WO2013039167A1 (ja) 2011-09-14 2013-03-21 塩野義製薬株式会社 吸入用医薬組成物
LT3473255T (lt) 2012-12-21 2022-03-10 Boehringer Ingelheim Vetmedica Gmbh Farmacinė vaisto forma, apimanti ciklezonidą
BR112015010842B1 (pt) * 2012-12-21 2021-03-30 Boehringer Ingelheim Vetmedica Gmbh Uso da ciclesonida para o tratamento de doença das vias respiratórias em cavalos
AU2015204558B2 (en) 2014-01-10 2020-04-30 Avalyn Pharma Inc. Aerosol pirfenidone and pyridone analog compounds and uses thereof
ES2759247T3 (es) 2014-06-18 2020-05-08 Boehringer Ingelheim Vetmedica Gmbh Antagonistas muscarínicos y combinaciones de estos para el tratamiento de enfermedades de las vías respiratorias en caballos
CA2960998A1 (en) 2014-09-11 2016-03-17 Synedgen, Inc. Compositions and methods of use thereof
KR20180030399A (ko) * 2015-08-05 2018-03-22 다이이찌 산쿄 가부시키가이샤 네뷸라이저용 조성물
CN106692163A (zh) * 2015-11-13 2017-05-24 天津金耀集团有限公司 一种吸入用环索奈德混悬液组合物
WO2019090405A1 (pt) * 2017-11-11 2019-05-16 Carvalho Junior Mario Virgilio De Medicamento de ciclesonida para cura e prevenção da gripe causada pelo vírus influenza
WO2020123336A1 (en) * 2018-12-13 2020-06-18 Qrumpharma Inc. Compositions of bedaquiline, combinations comprising them, processes for their preparation, uses and methods of treatment comprising them
WO2021221656A1 (en) 2020-04-30 2021-11-04 Synedgen, Inc. Compositions and methods of use thereof
US20210346613A1 (en) * 2020-05-05 2021-11-11 Mahesh Kumar KHAITAN Controlled delivery device for treating coronavirus infections and methods thereof
CN115835885B (zh) * 2020-06-23 2025-02-07 广州谷森制药有限公司 包含奥达特罗和布地奈德的药物组合物的制备
WO2022213101A1 (en) * 2021-04-01 2022-10-06 Vitrean Inc. Methods for manufacturing of highly concentrated hydrogels
WO2022231533A1 (en) * 2021-04-29 2022-11-03 Arven Ilac Sanayi Ve Ticaret Anonim Sirketi Process for the preparation of sterilized suspensions for the inhalation by nebulization

Family Cites Families (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE458986B (sv) * 1985-03-29 1989-05-29 Draco Ab Dosfoerpackning
SE8600632D0 (sv) 1986-02-13 1986-02-13 Kabivitrum Ab Novel pharmaceutical composition
GR1001529B (el) * 1990-09-07 1994-03-31 Elmuquimica Farm Sl Μέ?οδος για την λήψη νέων 21-εστέρων της 16-17-ακετάλης της πρ να-1,4-διενο-3,20-διόνης.
US5346702A (en) * 1992-12-04 1994-09-13 Sterling Winthrop Inc. Use of non-ionic cloud point modifiers to minimize nanoparticle aggregation during sterilization
DK0701565T3 (da) 1993-04-02 1999-07-12 Byk Gulden Lomberg Chem Fab Nye prednisolonderivater
US5540930A (en) * 1993-10-25 1996-07-30 Pharmos Corporation Suspension of loteprednol etabonate for ear, eye, or nose treatment
GB9410222D0 (en) 1994-05-21 1994-07-06 Glaxo Wellcome Australia Ltd Medicaments
DE4440337A1 (de) * 1994-11-11 1996-05-15 Dds Drug Delivery Services Ges Pharmazeutische Nanosuspensionen zur Arzneistoffapplikation als Systeme mit erhöhter Sättigungslöslichkeit und Lösungsgeschwindigkeit
DE19541689A1 (de) 1994-11-14 1996-05-15 Byk Gulden Lomberg Chem Fab Kombinationsarzneimittel
DE19635498A1 (de) 1996-09-03 1998-03-26 Byk Gulden Lomberg Chem Fab Verfahren zur Epimerenanreicherung
US6120752A (en) * 1997-05-21 2000-09-19 3M Innovative Properties Company Medicinal aerosol products containing formulations of ciclesonide and related steroids
SE9704186D0 (sv) * 1997-11-14 1997-11-14 Astra Ab New composition of matter
US6598603B1 (en) * 1997-12-31 2003-07-29 Astra Aktiebolag Method for treating respiratory diseases
TWI243687B (en) * 1998-04-21 2005-11-21 Teijin Ltd Pharmaceutical composition for application to mucosa
US6264923B1 (en) 1998-05-13 2001-07-24 3M Innovative Properties Company Medicinal aerosol formulation of ciclesonide and related compounds
KR100635456B1 (ko) 1998-05-29 2006-10-18 스키에파마 캐나다 인코포레이티드 열보호화 마이크로입자 조성물 및 그의 말단의 스팀멸균방법
US6241969B1 (en) * 1998-06-26 2001-06-05 Elan Corporation Plc Aqueous compositions containing corticosteroids for nasal and pulmonary delivery
IT1303692B1 (it) 1998-11-03 2001-02-23 Chiesi Farma Spa Procedimento per la preparazione di sospensioni di particelle difarmaci da somministrare per inalazione.
IT1313553B1 (it) * 1999-07-23 2002-09-09 Chiesi Farma Spa Formulazioni ottimizzate costituite da soluzioni di steroidi dasomministrare per inalazione.
AR026073A1 (es) * 1999-10-20 2002-12-26 Nycomed Gmbh Composicion farmaceutica acuosa que contiene ciclesonida
AR026072A1 (es) * 1999-10-20 2002-12-26 Nycomed Gmbh Composicion farmaceutica que contiene ciclesonida para aplicacion a la mucosa
CA2356177A1 (en) 1999-10-20 2001-04-26 Kazuya Takanashi Aqueous pharmaceutical compositions
DE10062712A1 (de) * 2000-12-15 2002-06-20 Boehringer Ingelheim Pharma Neue Arzneimittelkompositionen auf der Basis von Anticholinergika und Corticosteroiden
US20020183292A1 (en) * 2000-10-31 2002-12-05 Michel Pairet Pharmaceutical compositions based on anticholinergics and corticosteroids
BR0115584A (pt) * 2000-11-24 2003-09-23 Breath Ltd Esterilização de produtos farmacêuticos
US20030055026A1 (en) * 2001-04-17 2003-03-20 Dey L.P. Formoterol/steroid bronchodilating compositions and methods of use thereof
US6667344B2 (en) * 2001-04-17 2003-12-23 Dey, L.P. Bronchodilating compositions and methods
DE10145361A1 (de) * 2001-09-14 2003-04-03 Pari Gmbh Verfahren zur Herstellung von flüssigen, sterilen Zubereitungen zur Inhalation
WO2003035030A1 (en) 2001-10-24 2003-05-01 Pari Gmbh Kit for the preparation of a pharmaceutical composition
WO2003070285A1 (en) 2002-02-19 2003-08-28 Resolution Chemicals Limited Solvent-based sterilisation of pharmaceuticals
WO2003074558A2 (en) 2002-03-04 2003-09-12 Nymox Corporation Spheron components useful in determining compounds capable of treating symptoms of alzheimer's disease, and treatments and animal models produced therefrom
AU2003236093A1 (en) 2002-04-12 2003-10-27 Ajinomoto Co., Inc. Composition for preventing arteriosclerosis
ITMI20020808A1 (it) * 2002-04-17 2003-10-17 Chiesi Farma Spa Procedimento per la preparazione di una sospensione sterile di particelle di beclometasone dipropionato da somministrare per inalazione
JP4364486B2 (ja) 2002-07-02 2009-11-18 帝人株式会社 無菌水性懸濁製剤
EP3513813A1 (en) * 2002-07-02 2019-07-24 Astrazeneca Ciclesonide-containing sterile aqueous suspension
US20040023935A1 (en) * 2002-08-02 2004-02-05 Dey, L.P. Inhalation compositions, methods of use thereof, and process for preparation of same
CA2495830C (en) * 2002-08-30 2012-08-21 Altana Pharma Ag The use of the combination of ciclesonide and antihistamines for the treatment of allergic rhinitis
WO2004029574A1 (ja) 2002-09-24 2004-04-08 Fujitsu Limited 歪み波形制御装置、歪み規制部材、歪み波形制御装置の歪み波形制御方法、及び歪み波形制御プログラム
EP1556091A1 (en) 2002-10-04 2005-07-27 Elan Pharma International Limited Gamma irradiation of solid nanoparticulate active agents
ITMI20022674A1 (it) * 2002-12-18 2004-06-19 Chiesi Farma Spa Procedimento per la preparazione di formulazioni sterili a base di principi attivi farmaceutici cristallini micronizzati da somministrare come sospensioni acquose per inalazione.
EP1454636A1 (en) 2003-03-04 2004-09-08 Dompé S.P.A. Sterilization of glucocorticoid drug particles for pulmonary delivery
MY143936A (en) 2003-03-27 2011-07-29 Nycomed Gmbh Process for preparing crystalline ciclesonide with defined particle size
TWI359675B (en) * 2003-07-10 2012-03-11 Dey L P Bronchodilating β-agonist compositions
PT1670482E (pt) * 2003-09-16 2014-03-12 Takeda Gmbh Utilização de ciclesonida para o tratamento de doenças respiratórias
DE10347994A1 (de) * 2003-10-15 2005-06-16 Pari GmbH Spezialisten für effektive Inhalation Wässrige Aerosol-Zubereitung
DE602005026225D1 (de) 2004-03-12 2011-03-24 Cipla Ltd Sterilisationsprozess für Steroide
GB0410995D0 (en) 2004-05-17 2004-06-23 Norton Healthcare Ltd Heat sterilization of glucocorticosteroids
ITSA20040012A1 (it) 2004-09-07 2004-12-07 Genetec S P A Processo di sterilizzazione di un glucocorticosteroide.
GB0425266D0 (en) 2004-11-16 2004-12-15 Norton Healthcare Ltd Pharmaceutical manufacturing process

Also Published As

Publication number Publication date
IL175461A0 (en) 2006-09-05
TWI350757B (en) 2011-10-21
BRPI0416854B8 (pt) 2021-05-25
HK1098486A1 (zh) 2007-07-20
TW200524615A (en) 2005-08-01
UA87123C2 (uk) 2009-06-25
NZ547217A (en) 2009-05-31
NO20063047L (no) 2006-09-05
EP1697398B1 (en) 2012-07-04
PE20050941A1 (es) 2005-11-08
NO337225B1 (no) 2016-02-15
KR20060122890A (ko) 2006-11-30
WO2005058935A2 (en) 2005-06-30
CN100513417C (zh) 2009-07-15
CA2549038A1 (en) 2005-06-30
EP2319858B1 (en) 2017-08-09
ZA200603768B (en) 2007-10-31
CN1890256A (zh) 2007-01-03
EA012388B1 (ru) 2009-10-30
WO2005058935A3 (en) 2006-05-18
AR046892A1 (es) 2005-12-28
AU2004298447A1 (en) 2005-06-30
AU2004298447B2 (en) 2011-04-21
CA2549038C (en) 2014-08-05
BRPI0416854B1 (pt) 2018-05-02
MY159377A (en) 2016-12-30
BRPI0416854A (pt) 2007-02-13
CO5700832A2 (es) 2006-11-30
US20070117783A1 (en) 2007-05-24
JP5001657B2 (ja) 2012-08-15
US11052042B2 (en) 2021-07-06
JP2007513993A (ja) 2007-05-31
EP2319858A1 (en) 2011-05-11
EP1697398A2 (en) 2006-09-06
ECSP066608A (es) 2006-10-25
US20160015634A1 (en) 2016-01-21
EA200601091A1 (ru) 2006-12-29
IL175461A (en) 2013-12-31

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