KR100946944B1 - 양극성 장애의 예방 또는 치료용 카바메이트 화합물 - Google Patents

양극성 장애의 예방 또는 치료용 카바메이트 화합물 Download PDF

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Publication number
KR100946944B1
KR100946944B1 KR1020037011296A KR20037011296A KR100946944B1 KR 100946944 B1 KR100946944 B1 KR 100946944B1 KR 1020037011296 A KR1020037011296 A KR 1020037011296A KR 20037011296 A KR20037011296 A KR 20037011296A KR 100946944 B1 KR100946944 B1 KR 100946944B1
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South Korea
Prior art keywords
formula
delete delete
bipolar disorder
enantiomer
disorder
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Expired - Lifetime
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KR1020037011296A
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English (en)
Korean (ko)
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KR20030087010A (ko
Inventor
플라타살라만카를로스알
자오보유
트위만로이이
최용문
고든로버트
Original Assignee
오르토-맥네일 파마슈티칼, 인코퍼레이티드
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Publication of KR20030087010A publication Critical patent/KR20030087010A/ko
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Publication of KR100946944B1 publication Critical patent/KR100946944B1/ko
Assigned to 에스케이바이오팜 주식회사 reassignment 에스케이바이오팜 주식회사 권리의 전부이전등록 Assignors: 얀센 파마슈티칼즈, 인코포레이티드
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/325—Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pyridine Compounds (AREA)
KR1020037011296A 2001-02-27 2002-02-21 양극성 장애의 예방 또는 치료용 카바메이트 화합물 Expired - Lifetime KR100946944B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US27168101P 2001-02-27 2001-02-27
US60/271,681 2001-02-27
US10/081,766 2002-02-21
US10/081,766 US6562867B2 (en) 2001-02-27 2002-02-21 Carbamate compounds for use in preventing or treating bipolar disorder
PCT/US2002/005297 WO2002067921A1 (en) 2001-02-27 2002-02-21 Carbamate compounds for use in preventing or treating bipolar disorder

Publications (2)

Publication Number Publication Date
KR20030087010A KR20030087010A (ko) 2003-11-12
KR100946944B1 true KR100946944B1 (ko) 2010-03-15

Family

ID=26765948

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020037011296A Expired - Lifetime KR100946944B1 (ko) 2001-02-27 2002-02-21 양극성 장애의 예방 또는 치료용 카바메이트 화합물

Country Status (26)

Country Link
US (1) US6562867B2 (https=)
EP (1) EP1408953B1 (https=)
JP (1) JP4276837B2 (https=)
KR (1) KR100946944B1 (https=)
CN (1) CN1250215C (https=)
AT (1) ATE324108T1 (https=)
BR (1) BR0207644A (https=)
CA (1) CA2439475C (https=)
CY (1) CY1105330T1 (https=)
CZ (1) CZ20032300A3 (https=)
DE (1) DE60210976T2 (https=)
DK (1) DK1408953T3 (https=)
ES (1) ES2262801T3 (https=)
HU (1) HUP0303243A3 (https=)
IL (1) IL157590A0 (https=)
MX (1) MXPA03007717A (https=)
MY (1) MY129304A (https=)
NO (1) NO20033802L (https=)
NZ (1) NZ527988A (https=)
PL (1) PL364638A1 (https=)
PT (1) PT1408953E (https=)
RS (1) RS50677B (https=)
RU (1) RU2300372C2 (https=)
TW (1) TWI250872B (https=)
WO (1) WO2002067921A1 (https=)
ZA (1) ZA200307465B (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE267629T1 (de) * 2000-07-21 2004-06-15 Ortho Mcneil Pharm Inc Verwendung von carbamat verbindungen zur vorbeugung oder behandlung von neuropathischen- , cluster- und migräneartigen kopfschmerzen
EP1383489B1 (en) * 2001-02-27 2007-05-09 Ortho-Mcneil Pharmaceutical, Inc. Carbamate compounds for use in preventing or treating neurodegenerative disorders
IL157594A0 (en) 2001-02-27 2004-03-28 Ortho Mcneil Pharm Inc Carbamate compounds for use in preventing or treating anxiety disorders
ATE435014T1 (de) 2001-07-16 2009-07-15 Ortho Mcneil Pharm Inc Carbamate verbindungen zur vorbeugung oder behandlung von neuropathischen schmerzen
DK1809273T3 (da) * 2004-09-16 2010-08-02 Janssen Pharmaceutica Nv Anvendelse af 2-phenyl-1,2-ethandiol-(di)carbamater til behandling af epileptogenese
EP1890684B1 (en) 2005-06-08 2013-08-14 SK Biopharmaceuticals Co., Ltd. Treatment of sleep-wake disorders
US20070021501A1 (en) * 2005-07-12 2007-01-25 Twyman Roy E Methods of treating epileptogenesis
EP2081648A2 (en) * 2006-10-30 2009-07-29 Janssen Pharmaceutica, N.V. Carbamate compounds for use in treating depression
BRPI0718323A2 (pt) * 2006-10-31 2013-11-26 Janssen Pharmaceutica Nv Tratamento de transtornos invasivos do desenvolvimento.
US8609849B1 (en) 2010-11-30 2013-12-17 Fox Chase Chemical Diversity Center, Inc. Hydroxylated sulfamides exhibiting neuroprotective action and their method of use
CN105189451A (zh) * 2013-03-12 2015-12-23 比皮艾思药物研发有限公司 氨基甲酸苯酯化合物和包含该化合物的用于预防或治疗神经性毒气引起的疾病的组合物
US10195151B2 (en) 2016-09-06 2019-02-05 Jazz Pharmaceuticals International Iii Limited Formulations of (R)-2-amino-3-phenylpropyl carbamate
MX2019006940A (es) * 2016-12-14 2019-09-06 Sk Biopharmaceuticals Co Ltd Uso de compuestos de carbamato para prevencion, alivio o tratamiento del trastorno bipolar.
BR112019025286A2 (pt) 2017-06-02 2020-06-23 Jazz Pharmaceuticals Ireland Limited Métodos e composições para tratamento de sonolência excessiva
US10940133B1 (en) 2020-03-19 2021-03-09 Jazz Pharmaceuticals Ireland Limited Methods of providing solriamfetol therapy to subjects with impaired renal function

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6103759A (en) * 1996-01-16 2000-08-15 Sk Corporation Halogen substituted carbamate compounds from 2-phenyl-1, 2-ethanediol

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3313692A (en) * 1958-04-21 1967-04-11 Armour Pharma Method of inducing calming and muscle relaxation with carbamates
US3278380A (en) * 1962-02-06 1966-10-11 Armour Pharma Methods of calming employing diphenyl hydroxy carbamate compounds
US3265728A (en) * 1962-07-18 1966-08-09 Armour Pharma Substituted phenethyl carbamates
WO1995034563A1 (en) * 1994-06-16 1995-12-21 Pfizer Inc. Pyrazolo and pyrrolopyridines

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6103759A (en) * 1996-01-16 2000-08-15 Sk Corporation Halogen substituted carbamate compounds from 2-phenyl-1, 2-ethanediol

Also Published As

Publication number Publication date
JP4276837B2 (ja) 2009-06-10
ES2262801T3 (es) 2006-12-01
WO2002067921A1 (en) 2002-09-06
CY1105330T1 (el) 2010-03-03
DK1408953T3 (da) 2006-08-21
HK1063436A1 (en) 2004-12-31
BR0207644A (pt) 2004-03-09
RU2300372C2 (ru) 2007-06-10
EP1408953A1 (en) 2004-04-21
DE60210976D1 (de) 2006-06-01
CN1505506A (zh) 2004-06-16
KR20030087010A (ko) 2003-11-12
NO20033802D0 (no) 2003-08-26
RU2003128997A (ru) 2005-03-20
ATE324108T1 (de) 2006-05-15
PT1408953E (pt) 2006-07-31
TWI250872B (en) 2006-03-11
NO20033802L (no) 2003-10-22
HUP0303243A2 (hu) 2004-01-28
CA2439475A1 (en) 2002-09-06
RS50677B (sr) 2010-06-30
YU67803A (sh) 2006-08-17
MY129304A (en) 2007-03-30
DE60210976T2 (de) 2007-05-24
MXPA03007717A (es) 2005-11-08
NZ527988A (en) 2006-01-27
CA2439475C (en) 2010-05-18
ZA200307465B (en) 2005-03-17
IL157590A0 (en) 2004-03-28
CZ20032300A3 (cs) 2005-01-12
EP1408953B1 (en) 2006-04-26
US20020198257A1 (en) 2002-12-26
HUP0303243A3 (en) 2012-07-30
PL364638A1 (en) 2004-12-13
CN1250215C (zh) 2006-04-12
JP2004533415A (ja) 2004-11-04
US6562867B2 (en) 2003-05-13

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