CA2439475C - Carbamate compounds for use in preventing or treating bipolar disorder - Google Patents

Carbamate compounds for use in preventing or treating bipolar disorder Download PDF

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Publication number
CA2439475C
CA2439475C CA2439475A CA2439475A CA2439475C CA 2439475 C CA2439475 C CA 2439475C CA 2439475 A CA2439475 A CA 2439475A CA 2439475 A CA2439475 A CA 2439475A CA 2439475 C CA2439475 C CA 2439475C
Authority
CA
Canada
Prior art keywords
formula
enantiomer
phenyl
alkyl
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2439475A
Other languages
English (en)
French (fr)
Other versions
CA2439475A1 (en
Inventor
Carlos R. Plata-Salaman
Boyu Zhao
Roy E. Twyman
Yong Moon Choi
Robert Gordon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SK Biopharmaceuticals Co Ltd
Original Assignee
Ortho McNeil Pharmaceutical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho McNeil Pharmaceutical Inc filed Critical Ortho McNeil Pharmaceutical Inc
Publication of CA2439475A1 publication Critical patent/CA2439475A1/en
Application granted granted Critical
Publication of CA2439475C publication Critical patent/CA2439475C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/325Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pyridine Compounds (AREA)
CA2439475A 2001-02-27 2002-02-21 Carbamate compounds for use in preventing or treating bipolar disorder Expired - Fee Related CA2439475C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US27168101P 2001-02-27 2001-02-27
US60/271,681 2001-02-27
US10/081,766 2002-02-21
US10/081,766 US6562867B2 (en) 2001-02-27 2002-02-21 Carbamate compounds for use in preventing or treating bipolar disorder
PCT/US2002/005297 WO2002067921A1 (en) 2001-02-27 2002-02-21 Carbamate compounds for use in preventing or treating bipolar disorder

Publications (2)

Publication Number Publication Date
CA2439475A1 CA2439475A1 (en) 2002-09-06
CA2439475C true CA2439475C (en) 2010-05-18

Family

ID=26765948

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2439475A Expired - Fee Related CA2439475C (en) 2001-02-27 2002-02-21 Carbamate compounds for use in preventing or treating bipolar disorder

Country Status (26)

Country Link
US (1) US6562867B2 (https=)
EP (1) EP1408953B1 (https=)
JP (1) JP4276837B2 (https=)
KR (1) KR100946944B1 (https=)
CN (1) CN1250215C (https=)
AT (1) ATE324108T1 (https=)
BR (1) BR0207644A (https=)
CA (1) CA2439475C (https=)
CY (1) CY1105330T1 (https=)
CZ (1) CZ20032300A3 (https=)
DE (1) DE60210976T2 (https=)
DK (1) DK1408953T3 (https=)
ES (1) ES2262801T3 (https=)
HU (1) HUP0303243A3 (https=)
IL (1) IL157590A0 (https=)
MX (1) MXPA03007717A (https=)
MY (1) MY129304A (https=)
NO (1) NO20033802L (https=)
NZ (1) NZ527988A (https=)
PL (1) PL364638A1 (https=)
PT (1) PT1408953E (https=)
RS (1) RS50677B (https=)
RU (1) RU2300372C2 (https=)
TW (1) TWI250872B (https=)
WO (1) WO2002067921A1 (https=)
ZA (1) ZA200307465B (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE267629T1 (de) * 2000-07-21 2004-06-15 Ortho Mcneil Pharm Inc Verwendung von carbamat verbindungen zur vorbeugung oder behandlung von neuropathischen- , cluster- und migräneartigen kopfschmerzen
EP1383489B1 (en) * 2001-02-27 2007-05-09 Ortho-Mcneil Pharmaceutical, Inc. Carbamate compounds for use in preventing or treating neurodegenerative disorders
IL157594A0 (en) 2001-02-27 2004-03-28 Ortho Mcneil Pharm Inc Carbamate compounds for use in preventing or treating anxiety disorders
ATE435014T1 (de) 2001-07-16 2009-07-15 Ortho Mcneil Pharm Inc Carbamate verbindungen zur vorbeugung oder behandlung von neuropathischen schmerzen
DK1809273T3 (da) * 2004-09-16 2010-08-02 Janssen Pharmaceutica Nv Anvendelse af 2-phenyl-1,2-ethandiol-(di)carbamater til behandling af epileptogenese
EP1890684B1 (en) 2005-06-08 2013-08-14 SK Biopharmaceuticals Co., Ltd. Treatment of sleep-wake disorders
US20070021501A1 (en) * 2005-07-12 2007-01-25 Twyman Roy E Methods of treating epileptogenesis
EP2081648A2 (en) * 2006-10-30 2009-07-29 Janssen Pharmaceutica, N.V. Carbamate compounds for use in treating depression
BRPI0718323A2 (pt) * 2006-10-31 2013-11-26 Janssen Pharmaceutica Nv Tratamento de transtornos invasivos do desenvolvimento.
US8609849B1 (en) 2010-11-30 2013-12-17 Fox Chase Chemical Diversity Center, Inc. Hydroxylated sulfamides exhibiting neuroprotective action and their method of use
CN105189451A (zh) * 2013-03-12 2015-12-23 比皮艾思药物研发有限公司 氨基甲酸苯酯化合物和包含该化合物的用于预防或治疗神经性毒气引起的疾病的组合物
US10195151B2 (en) 2016-09-06 2019-02-05 Jazz Pharmaceuticals International Iii Limited Formulations of (R)-2-amino-3-phenylpropyl carbamate
MX2019006940A (es) * 2016-12-14 2019-09-06 Sk Biopharmaceuticals Co Ltd Uso de compuestos de carbamato para prevencion, alivio o tratamiento del trastorno bipolar.
BR112019025286A2 (pt) 2017-06-02 2020-06-23 Jazz Pharmaceuticals Ireland Limited Métodos e composições para tratamento de sonolência excessiva
US10940133B1 (en) 2020-03-19 2021-03-09 Jazz Pharmaceuticals Ireland Limited Methods of providing solriamfetol therapy to subjects with impaired renal function

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3313692A (en) * 1958-04-21 1967-04-11 Armour Pharma Method of inducing calming and muscle relaxation with carbamates
US3278380A (en) * 1962-02-06 1966-10-11 Armour Pharma Methods of calming employing diphenyl hydroxy carbamate compounds
US3265728A (en) * 1962-07-18 1966-08-09 Armour Pharma Substituted phenethyl carbamates
WO1995034563A1 (en) * 1994-06-16 1995-12-21 Pfizer Inc. Pyrazolo and pyrrolopyridines
US5698588A (en) * 1996-01-16 1997-12-16 Yukong Limited Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol

Also Published As

Publication number Publication date
JP4276837B2 (ja) 2009-06-10
ES2262801T3 (es) 2006-12-01
WO2002067921A1 (en) 2002-09-06
CY1105330T1 (el) 2010-03-03
DK1408953T3 (da) 2006-08-21
HK1063436A1 (en) 2004-12-31
BR0207644A (pt) 2004-03-09
RU2300372C2 (ru) 2007-06-10
EP1408953A1 (en) 2004-04-21
DE60210976D1 (de) 2006-06-01
CN1505506A (zh) 2004-06-16
KR20030087010A (ko) 2003-11-12
NO20033802D0 (no) 2003-08-26
RU2003128997A (ru) 2005-03-20
ATE324108T1 (de) 2006-05-15
PT1408953E (pt) 2006-07-31
TWI250872B (en) 2006-03-11
NO20033802L (no) 2003-10-22
HUP0303243A2 (hu) 2004-01-28
CA2439475A1 (en) 2002-09-06
RS50677B (sr) 2010-06-30
YU67803A (sh) 2006-08-17
MY129304A (en) 2007-03-30
DE60210976T2 (de) 2007-05-24
MXPA03007717A (es) 2005-11-08
NZ527988A (en) 2006-01-27
KR100946944B1 (ko) 2010-03-15
ZA200307465B (en) 2005-03-17
IL157590A0 (en) 2004-03-28
CZ20032300A3 (cs) 2005-01-12
EP1408953B1 (en) 2006-04-26
US20020198257A1 (en) 2002-12-26
HUP0303243A3 (en) 2012-07-30
PL364638A1 (en) 2004-12-13
CN1250215C (zh) 2006-04-12
JP2004533415A (ja) 2004-11-04
US6562867B2 (en) 2003-05-13

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Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed

Effective date: 20130221