CA2439475C - Carbamate compounds for use in preventing or treating bipolar disorder - Google Patents

Carbamate compounds for use in preventing or treating bipolar disorder Download PDF

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Publication number
CA2439475C
CA2439475C CA2439475A CA2439475A CA2439475C CA 2439475 C CA2439475 C CA 2439475C CA 2439475 A CA2439475 A CA 2439475A CA 2439475 A CA2439475 A CA 2439475A CA 2439475 C CA2439475 C CA 2439475C
Authority
CA
Canada
Prior art keywords
formula
enantiomer
phenyl
alkyl
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2439475A
Other languages
English (en)
French (fr)
Other versions
CA2439475A1 (en
Inventor
Carlos R. Plata-Salaman
Boyu Zhao
Roy E. Twyman
Yong Moon Choi
Robert Gordon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SK Biopharmaceuticals Co Ltd
Original Assignee
Ortho McNeil Pharmaceutical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho McNeil Pharmaceutical Inc filed Critical Ortho McNeil Pharmaceutical Inc
Publication of CA2439475A1 publication Critical patent/CA2439475A1/en
Application granted granted Critical
Publication of CA2439475C publication Critical patent/CA2439475C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/325Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pyridine Compounds (AREA)
CA2439475A 2001-02-27 2002-02-21 Carbamate compounds for use in preventing or treating bipolar disorder Expired - Fee Related CA2439475C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US27168101P 2001-02-27 2001-02-27
US60/271,681 2001-02-27
PCT/US2002/005297 WO2002067921A1 (en) 2001-02-27 2002-02-21 Carbamate compounds for use in preventing or treating bipolar disorder
US10/081,766 2002-02-21
US10/081,766 US6562867B2 (en) 2001-02-27 2002-02-21 Carbamate compounds for use in preventing or treating bipolar disorder

Publications (2)

Publication Number Publication Date
CA2439475A1 CA2439475A1 (en) 2002-09-06
CA2439475C true CA2439475C (en) 2010-05-18

Family

ID=26765948

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2439475A Expired - Fee Related CA2439475C (en) 2001-02-27 2002-02-21 Carbamate compounds for use in preventing or treating bipolar disorder

Country Status (26)

Country Link
US (1) US6562867B2 (https=)
EP (1) EP1408953B1 (https=)
JP (1) JP4276837B2 (https=)
KR (1) KR100946944B1 (https=)
CN (1) CN1250215C (https=)
AT (1) ATE324108T1 (https=)
BR (1) BR0207644A (https=)
CA (1) CA2439475C (https=)
CY (1) CY1105330T1 (https=)
CZ (1) CZ20032300A3 (https=)
DE (1) DE60210976T2 (https=)
DK (1) DK1408953T3 (https=)
ES (1) ES2262801T3 (https=)
HU (1) HUP0303243A3 (https=)
IL (1) IL157590A0 (https=)
MX (1) MXPA03007717A (https=)
MY (1) MY129304A (https=)
NO (1) NO20033802L (https=)
NZ (1) NZ527988A (https=)
PL (1) PL364638A1 (https=)
PT (1) PT1408953E (https=)
RS (1) RS50677B (https=)
RU (1) RU2300372C2 (https=)
TW (1) TWI250872B (https=)
WO (1) WO2002067921A1 (https=)
ZA (1) ZA200307465B (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7349301A (en) * 2000-07-21 2002-02-05 Ortho Mcneil Pharm Inc Carbamate compounds for use in preventing or treating neuropathic pain and cluster and migraine headache-associated pain
ES2262826T3 (es) 2001-02-27 2006-12-01 Ortho-Mcneil Pharmaceutical, Inc. Uso de un compuesto de carbamato en la prevencion o el tratamiento de transtornos de ansiedad.
PL364680A1 (en) * 2001-02-27 2004-12-13 Ortho-Mcneil Pharmaceutical, Inc. Carbamate compounds for use in preventing or treating neurodegenerative disorders
PL368164A1 (en) 2001-07-16 2005-03-21 Ortho-Mcneil Pharmaceutical, Inc. Carbamate compounds for use in preventing or treating neuropathic pain and cluster and migraine headache-associated pain
CA2580640A1 (en) * 2004-09-16 2006-03-30 Janssen Pharmaceutica N.V. Methods of treating epileptogensis and epilepsy
ES2435403T3 (es) 2005-06-08 2013-12-19 Sk Biopharmaceuticals Co., Ltd. Tratamiento de trastornos del sueño y vigilia
US20070021501A1 (en) * 2005-07-12 2007-01-25 Twyman Roy E Methods of treating epileptogenesis
CA2667949A1 (en) * 2006-10-30 2008-05-08 Janssen Pharmaceutica N.V. Methods for treating depression
MX2009004798A (es) * 2006-10-31 2009-08-12 Janssen Pharmaceutica Nv Tratamiento de los trastornos generalizados del desarrollo.
US8609849B1 (en) 2010-11-30 2013-12-17 Fox Chase Chemical Diversity Center, Inc. Hydroxylated sulfamides exhibiting neuroprotective action and their method of use
US9566261B2 (en) * 2013-03-12 2017-02-14 Bio-Pharm Solutions Co., Ltd. Phenyl carbamate compound and a composition for preventing or treating a memory loss-related disease comprising the same
US10195151B2 (en) 2016-09-06 2019-02-05 Jazz Pharmaceuticals International Iii Limited Formulations of (R)-2-amino-3-phenylpropyl carbamate
KR102635938B1 (ko) * 2016-12-14 2024-02-13 에스케이바이오팜 주식회사 양극성 장애의 예방, 경감 또는 치료를 위한 카바메이트 화합물의 용도
AU2018278332B2 (en) 2017-06-02 2022-05-19 Jazz Pharmaceuticals Ireland Limited Methods and compositions for treating excessive sleepiness
US10940133B1 (en) 2020-03-19 2021-03-09 Jazz Pharmaceuticals Ireland Limited Methods of providing solriamfetol therapy to subjects with impaired renal function

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3313692A (en) * 1958-04-21 1967-04-11 Armour Pharma Method of inducing calming and muscle relaxation with carbamates
US3278380A (en) * 1962-02-06 1966-10-11 Armour Pharma Methods of calming employing diphenyl hydroxy carbamate compounds
US3265728A (en) * 1962-07-18 1966-08-09 Armour Pharma Substituted phenethyl carbamates
DK0765327T3 (da) * 1994-06-16 1999-11-29 Pfizer Pyrazolo- og pyrrolopyridiner
US5698588A (en) * 1996-01-16 1997-12-16 Yukong Limited Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol

Also Published As

Publication number Publication date
CA2439475A1 (en) 2002-09-06
KR100946944B1 (ko) 2010-03-15
CZ20032300A3 (cs) 2005-01-12
MY129304A (en) 2007-03-30
TWI250872B (en) 2006-03-11
ZA200307465B (en) 2005-03-17
DE60210976D1 (de) 2006-06-01
ATE324108T1 (de) 2006-05-15
EP1408953B1 (en) 2006-04-26
HUP0303243A2 (hu) 2004-01-28
RS50677B (sr) 2010-06-30
MXPA03007717A (es) 2005-11-08
NZ527988A (en) 2006-01-27
US20020198257A1 (en) 2002-12-26
PT1408953E (pt) 2006-07-31
DK1408953T3 (da) 2006-08-21
RU2300372C2 (ru) 2007-06-10
WO2002067921A1 (en) 2002-09-06
US6562867B2 (en) 2003-05-13
CN1250215C (zh) 2006-04-12
HUP0303243A3 (en) 2012-07-30
JP2004533415A (ja) 2004-11-04
YU67803A (sh) 2006-08-17
JP4276837B2 (ja) 2009-06-10
PL364638A1 (en) 2004-12-13
BR0207644A (pt) 2004-03-09
NO20033802L (no) 2003-10-22
ES2262801T3 (es) 2006-12-01
HK1063436A1 (en) 2004-12-31
NO20033802D0 (no) 2003-08-26
DE60210976T2 (de) 2007-05-24
KR20030087010A (ko) 2003-11-12
EP1408953A1 (en) 2004-04-21
IL157590A0 (en) 2004-03-28
CN1505506A (zh) 2004-06-16
CY1105330T1 (el) 2010-03-03
RU2003128997A (ru) 2005-03-20

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Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed

Effective date: 20130221