KR100922199B1 - Cosmetic composition with the anti-aging effect of skin - Google Patents

Abstract

The present invention relates to a cosmetic composition having an excellent effect of inhibiting the generation of wrinkles by inhibiting skin aging, and more specifically, the main herbal ingredients contain baekbokyeong, tangwi, cheongung, samchil, cheonmundong extract to inhibit skin aging and wrinkles It is to provide a cosmetic composition excellent in the effect of inhibiting the formation of.

Skin aging, cosmetics, baekbok-ryeong, donkey

Description

Cosmetic composition with the anti-aging effect of skin}

The present invention relates to a cosmetic composition having an excellent effect of inhibiting wrinkles by inhibiting skin aging, and more particularly, by containing the extracts of Baekbokyeong, Dongguk, Cheongung, Samchil, and Astronomical Dong as main herbal ingredients to suppress skin aging to produce wrinkles. It relates to a cosmetic composition that can provide an effect of inhibiting.

The skin protects the organs of the body from changes in temperature and humidity and irritation of the external environment such as ultraviolet rays. However, the constant physical and chemical stimuli from the outside reduce the function of the skin and promote the aging of the skin. The aging of the skin also entails a general deterioration of the skin components, resulting in easy cracking of the skin. Reduction of fibroblasts and impaired activity of these cells are an important part of the skin aging process. In order to prevent the aging phenomenon and maintain a more healthy and beautiful skin, by using cosmetics reinforced with conventional bioactive substances obtained from various plants, animals, and microorganisms, the skin's inherent functions are maintained and skin cells are activated effectively. Efforts have been made to curb. However, existing cosmetic raw materials have various problems such as insufficient efficacy or cause skin side effects.

Recently, in an effort to develop relatively low-toxic and nature-friendly cosmetics, it has been discovered that several plants are effective in suppressing skin aging and wrinkles by searching for plants having a radical scavenging function. For example, radical scavengers containing extracts of three hundred seconds have been reported, radical scavengers containing extracts of the pheasant's aquatic plant have been known, skin wrinkle improvement cosmetics containing yulpi extract have been known, cosmetic compositions containing enamel oil, etc. Although it has been reported, there is no known effect of inhibiting wrinkles by inhibiting skin aging by radical removal using extracts of Baekbok-ryeong, Dang-guk, Cheong-gung, Cheon-gung, Samcheon, and Cheonmun-dong as natural herbal medicines rather than a single product.

The present invention is to solve the above problems, as part of the research to develop a cosmetic composition excellent in the ability to remove the active oxygen species using a natural herbal medicine for inhibiting skin aging to suppress the generation of wrinkles from various natural products As a result of considering the properties of herbal extracts extracted with water or organic solvent, it is a cosmetic composition that has the effect of inhibiting skin aging by inhibiting skin aging, and it contains main herbal medicines, ie, Baekbokyeong, Donkey, Cheongung, Samchil, and Astronomical Dong extracts. It is to provide a cosmetic composition excellent in suppressing the effect of inhibiting the generation of wrinkles.

Hereinafter, the present invention will be described in more detail.

The present invention relates to a cosmetic composition having the effect of inhibiting the generation of wrinkles by inhibiting skin aging, and more specifically, the main herbal ingredients contain Baekbokyeong, Dongguk, Cheongung, Samchil, Astronomical Dong extract, various bases and additives for cosmetics Solubility, affinity, and stability in organic solvents and the like are good, and it provides an effect of inhibiting the generation of wrinkles by inhibiting skin aging.

The composition of each herbal ingredient in the composition according to the present invention is 30 to 35% by weight, 10 to 15% by weight, Cheongung 20 to 25% by weight, Samil 10 to 15% by weight, Cheonmundong 20 based on the respective dry weight. It is used in combination in the ratio of 25 weight%.

10 times distilled water was added to the herbal extracts mixed at the above compounding ratio, and extracted three times for 5 hours at 100 ± 10 ° C., filtered, concentrated under reduced pressure, and added to prepare cosmetics.

The cosmetic composition according to the present invention is characterized in that it contains 0.1 to 5% by weight of the prepared herbal extract to preferably 1% by weight.

Cosmetic compositions having the effect of inhibiting wrinkles generation by inhibiting skin aging according to the present invention may have a conventional formulation, for example, supple cosmetics, astringent cosmetics, nourishing cosmetics, nutrition cream, body lotion, body oil, body Formulated as an essence and the like. The composition of each of these formulations may contain a variety of bases and additives necessary for the formulation of the formulation and are suitable, and the types and amounts of these components can be readily selected by those skilled in the art. Hereinafter, a typical skin and lotion composition of a cosmetic composition having an effect of inhibiting skin aging and suppressing wrinkle generation will be described.                     

In addition, the cosmetic composition having the effect of inhibiting the generation of wrinkles by inhibiting skin aging according to the present invention can be used according to a conventional method of use, the number of times of use can vary depending on the user's skin condition or taste.

Hereinafter, the cosmetic composition having the effect of inhibiting the generation of wrinkles by inhibiting skin aging of the present invention through embodiments of the present invention will be described in more detail, but the present invention is not limited to these examples.

Example 1 Preparation of Herbal Extracts

The herbal extract was used to powder the dried herbal medicine.

10 times distilled water was added to the mixed herbal medicines as shown in Table 1, followed by repeated extraction three times at 100 ± 10 ° C. for 5 hours, followed by filtration and concentration under reduced pressure to obtain 2 g of herbal medicine extracts.

TABLE 1

Example 2 Preparation of Skin Lotion Having an Effect of Inhibiting Skin Aging According to the Present Invention

A skin lotion was prepared at the composition ratio as shown in Table 2 below. The alcohol part was produced by dissolving in the order of MP, tween 20, NP-12 in 78 ° C. distilled alcohol, and the purified water part was glycerin, 1,3-BG, DC-193, in sterilized purified water. A skin lotion was prepared by dissolving hyaluronic acid, allantoin, citric acid, and sodium citrate in order, followed by mixing with the herbal extract prepared in Example 1 above.

TABLE 2

Example 3: Preparation of milk lotion having the effect of inhibiting skin aging according to the present invention

Milk lotion was prepared in the same manner as in Example 2.                     

TABLE 3

Experimental Example 1: Confirming the skin aging inhibitory effect of the skin lotion according to the present invention

The skin lotion prepared in Example 2 was applied to the forearm of 20 healthy adult males by a predetermined amount (10 m / 5 cm 2), and the remaining area was shielded with aluminum foil, and 30 minutes later, long-wave UV light was applied using an ultraviolet irradiator. The skin condition (erythema, edema, papules, etc.) was observed 24 hours after irradiation at a dose of 10.2 J / cm 2. As a result, skin side effects such as erythema do not occur on the skin, and thus the skin lotion has no phototoxicity and has an effect of inhibiting skin aging.

Experimental Example 2: Confirmation of skin aging inhibitory effect of milk lotion according to the present invention

Apply the milk lotion prepared in Example 3 to the forearm of 20 healthy adult males by a predetermined amount (10m / 5cm 2), shielding the other area with aluminum foil, and after 30 minutes, apply long-wavelength ultraviolet rays using an ultraviolet irradiator. The skin condition (erythema, edema, papules, etc.) was observed 24 hours after irradiation at a dose of 10.2 J / cm 2. As a result, the side effects such as erythema do not occur on the skin, and thus the milk lotion has no phototoxicity and has an effect of inhibiting skin aging.

Experimental Example 3: Skin stability confirmation test of skin lotion and milk lotion according to the present invention

Skin patch and milk lotion prepared in Examples 2 and 3 were subjected to a human patch test on the forearm of 20 healthy adult males. Wipe the forearm of the subject well with 70% ethanol, and then place a pin chamber containing 20 μl of the skin lotion and milk lotion prepared in Examples 2 and 3 on a conventional cosmetic base using adhesive tape for 24 hours. Closed attachment. After 24 hours, the adhesive tape and the pin chamber were removed, and the sample remaining on the skin with a gauze was lightly removed, and then the skin condition was observed, and again after 24 hours. Experimental results As shown in Table 4, in the human patch test to confirm the skin irritation of the skin lotion and milk lotion according to the present invention did not show a positive response was confirmed that there is no irritation to the human skin.

TABLE 4

Experimental Example 4: Protective effect of cell death treated with hydrogen peroxide of Baekbokryeong, Dangui, Cheongung, Samchil, Astronomical Dong extracts according to the present invention

To evaluate the protective effect of the Baekbokyeong, Angelica, Cheongung, Samchil, Astronomical Dong extract obtained in Example 1 against cell death induced by the treatment of hydrogen peroxide was evaluated the protective effect against cell stimulation by reactive oxygen species.

First, NIH3T3 cells were injected into 65 mm Petri dishes at a concentration of 1 × 10 ⁶ / ml at 5 ml to induce cell adhesion. After treatment with hydrogen peroxide at 0, 1, 2, 5, 10 mM each, and incubated for 24 hours to evaluate the protective effect against cell death. The following cell viability evaluation was performed by the Sulfurhodamine B assay.

As shown in Table 5, the extracts of Baekbokryeong, Donkey, Cheongung, Samchil, and Astronomical Dong obtained in Example 1 showed the best cell death protection effect when treated with 1% by weight.

Thus, the extracts of Baekbokryeong, Donkey, Cheongung, Samchil, and Astronomical Dong obtained in Example 1 with respect to reactive oxygen species showed an excellent effect of inhibiting skin aging.

TABLE 5

The cosmetics of the present invention through the above Examples and Experimental Examples contain a natural active ingredient derived from natural herbal medicines, Baekbokyeong, Dongguk, Cheongung, Samchil, and Astronomical Dong extracts, which are excellent in inhibiting the generation of wrinkles by inhibiting skin aging. It is to provide a cosmetic composition.

Claims (3)

Herbal extract having the effect of inhibiting skin aging, characterized in that it comprises a mixed extract consisting of Baekbokyeong, Angelica, Cheonggung, Samchil, astronomical dong, each herbal composition is based on the dry weight of each 30 To 35% by weight, Angelica 10 to 15% by weight, 20 to 25% by weight, Shamil 10 to 15% by weight, 20 to 25% by weight of astronomical dong, characterized in that the cosmetic composition for inhibiting skin aging. delete 30 to 35% by weight, Angelica 10 to 15% by weight, Cheongung 20 to 25% by weight, Samilchi 10 to 15% by weight, 20 to 25% by weight of astronomical dong based on the dry weight and filtered by hot water extraction And Method of producing a cosmetic composition for inhibiting skin aging, characterized in that it comprises 0.1 to 5% by weight of the herbal extract prepared by the step of concentration under reduced pressure