KR100878698B1 - 결정형의 베포타스틴 금속염 수화물, 이의 제조방법 및이를 포함하는 약학 조성물 - Google Patents
결정형의 베포타스틴 금속염 수화물, 이의 제조방법 및이를 포함하는 약학 조성물 Download PDFInfo
- Publication number
- KR100878698B1 KR100878698B1 KR1020070033756A KR20070033756A KR100878698B1 KR 100878698 B1 KR100878698 B1 KR 100878698B1 KR 1020070033756 A KR1020070033756 A KR 1020070033756A KR 20070033756 A KR20070033756 A KR 20070033756A KR 100878698 B1 KR100878698 B1 KR 100878698B1
- Authority
- KR
- South Korea
- Prior art keywords
- bepotastine
- metal salt
- same
- present
- intensity
- Prior art date
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-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Immunology (AREA)
- Otolaryngology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Description
<화학식 3>
<화학식 4>
Claims (14)
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Priority Applications (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020070033756A KR100878698B1 (ko) | 2007-04-05 | 2007-04-05 | 결정형의 베포타스틴 금속염 수화물, 이의 제조방법 및이를 포함하는 약학 조성물 |
TW097112166A TW200900392A (en) | 2007-04-05 | 2008-04-03 | Novel crystalline bepotastine metal salt hydrate, method for preparing same, and pharmaceutical composition comprising same |
EP08741162A EP2144896A4 (en) | 2007-04-05 | 2008-04-04 | CRYSTALLINE BEPOTASTIN METAL SALT HYDRATE, PROCESS FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAID HYDRATE |
PCT/KR2008/001912 WO2008123701A1 (en) | 2007-04-05 | 2008-04-04 | Novel crystalline bepotastine metal salt hydrate, method for preparing same, and pharmaceutical composition comprising same |
US12/531,003 US20100137367A1 (en) | 2007-04-05 | 2008-04-04 | Novel crystalline bepotastine metal salt hydrate, method for preparing same, and pharmaceutical composition comprising same |
JP2010500837A JP2010522747A (ja) | 2007-04-05 | 2008-04-04 | 新規な結晶型ベポタスチン金属塩水和物、その製造方法及びこれを含む医薬組成物 |
AU2008235668A AU2008235668A1 (en) | 2007-04-05 | 2008-04-04 | Novel crystalline bepotastine metal salt hydrate, method for preparing same, and pharmaceutical composition comprising same |
CN200880010709A CN101652358A (zh) | 2007-04-05 | 2008-04-04 | 新型晶体贝他斯汀金属盐水合物、它的制备方法和包含它的药物组合物 |
CA002682822A CA2682822A1 (en) | 2007-04-05 | 2008-04-04 | Novel crystalline bepotastine metal salt hydrate, method for preparing same, and pharmaceutical composition comprising same |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020070033756A KR100878698B1 (ko) | 2007-04-05 | 2007-04-05 | 결정형의 베포타스틴 금속염 수화물, 이의 제조방법 및이를 포함하는 약학 조성물 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1020080121442A Division KR101307712B1 (ko) | 2008-12-02 | 2008-12-02 | 결정형의 베포타스틴 금속염 수화물, 이의 제조방법 및 이를 포함하는 약학 조성물 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR20080090661A KR20080090661A (ko) | 2008-10-09 |
KR100878698B1 true KR100878698B1 (ko) | 2009-01-13 |
Family
ID=39831122
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1020070033756A KR100878698B1 (ko) | 2007-04-05 | 2007-04-05 | 결정형의 베포타스틴 금속염 수화물, 이의 제조방법 및이를 포함하는 약학 조성물 |
Country Status (9)
Country | Link |
---|---|
US (1) | US20100137367A1 (ko) |
EP (1) | EP2144896A4 (ko) |
JP (1) | JP2010522747A (ko) |
KR (1) | KR100878698B1 (ko) |
CN (1) | CN101652358A (ko) |
AU (1) | AU2008235668A1 (ko) |
CA (1) | CA2682822A1 (ko) |
TW (1) | TW200900392A (ko) |
WO (1) | WO2008123701A1 (ko) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101307712B1 (ko) | 2008-12-02 | 2013-09-11 | 한미사이언스 주식회사 | 결정형의 베포타스틴 금속염 수화물, 이의 제조방법 및 이를 포함하는 약학 조성물 |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100879409B1 (ko) * | 2007-06-11 | 2009-01-19 | 한미약품 주식회사 | (s)-베포타스틴의 제조방법 및 이에 사용되는 중간체 |
JP2011195500A (ja) * | 2010-03-19 | 2011-10-06 | Tokuyama Corp | (s)−4−[4−[(4−クロロフェニル)(2−ピリジル)メトキシ]ピペリジノ]ブタン酸一ベンゼンスルホン酸塩の製造方法 |
WO2012048059A2 (en) * | 2010-10-06 | 2012-04-12 | Ista Pharmaceuticals, Inc. | Bepotastine compositions |
JP5683719B2 (ja) | 2011-01-04 | 2015-03-11 | イスタ・ファーマシューティカルズ・インコーポレイテッドIsta Pharmaceuticals,Inc. | ベポタスチン組成物 |
US9800605B2 (en) * | 2015-01-30 | 2017-10-24 | Securonix, Inc. | Risk scoring for threat assessment |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20050058400A (ko) * | 2002-08-30 | 2005-06-16 | 알타나 파마 아게 | 알레르기성 비염을 치료하기 위한 사이클레소나이드 및 항히스타민제의 조합물의 용도 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW486475B (en) | 1996-12-26 | 2002-05-11 | Ube Industries | Acid addition salt of optically active piperidine compound and process for preparing the same |
JP3909998B2 (ja) * | 2000-03-22 | 2007-04-25 | 田辺製薬株式会社 | 経口投与製剤 |
JP2002212067A (ja) * | 2001-01-15 | 2002-07-31 | Taisho Pharmaceut Co Ltd | 風邪治療用組成物 |
JP4365107B2 (ja) * | 2001-05-25 | 2009-11-18 | エスエス製薬株式会社 | 医薬組成物 |
-
2007
- 2007-04-05 KR KR1020070033756A patent/KR100878698B1/ko active IP Right Grant
-
2008
- 2008-04-03 TW TW097112166A patent/TW200900392A/zh unknown
- 2008-04-04 US US12/531,003 patent/US20100137367A1/en not_active Abandoned
- 2008-04-04 AU AU2008235668A patent/AU2008235668A1/en not_active Abandoned
- 2008-04-04 EP EP08741162A patent/EP2144896A4/en not_active Withdrawn
- 2008-04-04 WO PCT/KR2008/001912 patent/WO2008123701A1/en active Application Filing
- 2008-04-04 CA CA002682822A patent/CA2682822A1/en not_active Abandoned
- 2008-04-04 CN CN200880010709A patent/CN101652358A/zh active Pending
- 2008-04-04 JP JP2010500837A patent/JP2010522747A/ja not_active Withdrawn
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20050058400A (ko) * | 2002-08-30 | 2005-06-16 | 알타나 파마 아게 | 알레르기성 비염을 치료하기 위한 사이클레소나이드 및 항히스타민제의 조합물의 용도 |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101307712B1 (ko) | 2008-12-02 | 2013-09-11 | 한미사이언스 주식회사 | 결정형의 베포타스틴 금속염 수화물, 이의 제조방법 및 이를 포함하는 약학 조성물 |
Also Published As
Publication number | Publication date |
---|---|
CN101652358A (zh) | 2010-02-17 |
EP2144896A1 (en) | 2010-01-20 |
KR20080090661A (ko) | 2008-10-09 |
US20100137367A1 (en) | 2010-06-03 |
CA2682822A1 (en) | 2008-10-16 |
TW200900392A (en) | 2009-01-01 |
WO2008123701A1 (en) | 2008-10-16 |
EP2144896A4 (en) | 2011-06-29 |
JP2010522747A (ja) | 2010-07-08 |
AU2008235668A1 (en) | 2008-10-16 |
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