KR100873748B1 - 통증 예방요법용 약물의 제조를 위한 아세틸ｌ-카르니틴의 용도 - Google Patents

통증 예방요법용 약물의 제조를 위한 아세틸ｌ-카르니틴의 용도 Download PDF

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Publication number
KR100873748B1
KR100873748B1 KR1020037015574A KR20037015574A KR100873748B1 KR 100873748 B1 KR100873748 B1 KR 100873748B1 KR 1020037015574 A KR1020037015574 A KR 1020037015574A KR 20037015574 A KR20037015574 A KR 20037015574A KR 100873748 B1 KR100873748 B1 KR 100873748B1
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South Korea
Prior art keywords
acetyl
carnitine
acid
days
treatment
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Expired - Fee Related
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KR1020037015574A
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English (en)
Korean (ko)
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KR20040003030A (ko
Inventor
메노티 칼바니
루이지 모스코니
Original Assignee
시그마타우 인두스트리에 파르마슈티케 리우니테 에스.피.에이.
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Application filed by 시그마타우 인두스트리에 파르마슈티케 리우니테 에스.피.에이. filed Critical 시그마타우 인두스트리에 파르마슈티케 리우니테 에스.피.에이.
Publication of KR20040003030A publication Critical patent/KR20040003030A/ko
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Publication of KR100873748B1 publication Critical patent/KR100873748B1/ko
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/221—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having an amino group, e.g. acetylcholine, acetylcarnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Emergency Medicine (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
KR1020037015574A 2001-05-29 2002-05-24 통증 예방요법용 약물의 제조를 위한 아세틸ｌ-카르니틴의 용도 Expired - Fee Related KR100873748B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT2001RM000293A ITRM20010293A1 (it) 2001-05-29 2001-05-29 Uso della acetil-l-carnetina per la preparazione di un medicamento per la prevenzione del dolore.
ITRM01A000293 2001-05-29
PCT/IT2002/000336 WO2002096409A1 (en) 2001-05-29 2002-05-24 Use of acetyl l-carnitine for the preparation of a medication for the preventive therapy for pain

Publications (2)

Publication Number Publication Date
KR20040003030A KR20040003030A (ko) 2004-01-07
KR100873748B1 true KR100873748B1 (ko) 2008-12-12

Family

ID=11455557

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020037015574A Expired - Fee Related KR100873748B1 (ko) 2001-05-29 2002-05-24 통증 예방요법용 약물의 제조를 위한 아세틸ｌ-카르니틴의 용도

Country Status (18)

Country Link
US (2) US20040152781A1 (enExample)
EP (1) EP1399141B1 (enExample)
JP (1) JP4287660B2 (enExample)
KR (1) KR100873748B1 (enExample)
AT (1) ATE374021T1 (enExample)
CA (1) CA2448242C (enExample)
CY (1) CY1107037T1 (enExample)
CZ (1) CZ20033220A3 (enExample)
DE (1) DE60222662T2 (enExample)
DK (1) DK1399141T3 (enExample)
ES (1) ES2290292T3 (enExample)
HU (1) HUP0401294A3 (enExample)
IT (1) ITRM20010293A1 (enExample)
MX (1) MXPA03010919A (enExample)
PL (1) PL367616A1 (enExample)
PT (1) PT1399141E (enExample)
SK (1) SK287559B6 (enExample)
WO (1) WO2002096409A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITRM20040606A1 (it) * 2004-12-13 2005-03-13 Sigma Tau Ind Farmaceuti Uso della acetil l-carnitina per il trattamento della sindrome fibromialgica.
JP5685362B2 (ja) * 2005-04-26 2015-03-18 シグマ−タウ・インドゥストリエ・ファルマチェウチケ・リウニテ・ソシエタ・ペル・アチオニＳｉｇｍａ−Ｔａｕ Ｉｎｄｕｓｔｒｉｅ Ｆａｒｍａｃｅｕｔｉｃｈｅ Ｒｉｕｎｉｔｅ Ｓｏｃｉｅｔａ Ｐｅｒ Ａｚｉｏｎｉ 有痛性末梢糖尿病性神経障害の予防のためのアセチルｌ−カルニチン
IT202200022437A1 (it) 2022-11-02 2024-05-02 Chiesi Italia S P A Composizione farmaceutica comprendente l-acetilcarnitina e beta-cariofillene

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0150688B1 (en) * 1983-12-28 1987-04-22 Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. Salts of l-carnitine and alkanoyl l-carnitines and process for preparing same
IT1196564B (it) * 1986-08-04 1988-11-16 Sigma Tau Ind Farmaceuti Impiego di acetil l-carnitina nel trattamento terapeutico delle neuropatie periferiche
IT1277147B1 (it) * 1995-01-20 1997-11-04 Sigma Tau Ind Farmaceuti Uso della carnitina e i suoi derivati per ridurre gli effetti tossici della ciclosporina-a e di altri farmaci immunosoppressivi.

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
International journal of clinical pharmacology research, 15(1), 1995, p.9-15

Also Published As

Publication number Publication date
DK1399141T3 (da) 2008-01-02
SK15842003A3 (sk) 2004-06-08
DE60222662T2 (de) 2008-06-26
CY1107037T1 (el) 2012-09-26
PT1399141E (pt) 2007-11-16
HUP0401294A2 (hu) 2004-12-28
ITRM20010293A1 (it) 2002-11-29
EP1399141A1 (en) 2004-03-24
WO2002096409A1 (en) 2002-12-05
JP4287660B2 (ja) 2009-07-01
CA2448242C (en) 2011-01-11
PL367616A1 (en) 2005-03-07
DE60222662D1 (de) 2007-11-08
JP2004532865A (ja) 2004-10-28
ES2290292T3 (es) 2008-02-16
SK287559B6 (sk) 2011-02-04
ITRM20010293A0 (it) 2001-05-29
CA2448242A1 (en) 2002-12-05
HUP0401294A3 (en) 2008-04-28
CZ20033220A3 (en) 2004-06-16
ATE374021T1 (de) 2007-10-15
US20040152781A1 (en) 2004-08-05
KR20040003030A (ko) 2004-01-07
US20090062388A1 (en) 2009-03-05
MXPA03010919A (es) 2004-02-27
EP1399141B1 (en) 2007-09-26

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