CA2448242C - Use of acetyl l-carnitine for the preparation of a medication for the preventive therapy for pain - Google Patents

Use of acetyl l-carnitine for the preparation of a medication for the preventive therapy for pain Download PDF

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Publication number
CA2448242C
CA2448242C CA2448242A CA2448242A CA2448242C CA 2448242 C CA2448242 C CA 2448242C CA 2448242 A CA2448242 A CA 2448242A CA 2448242 A CA2448242 A CA 2448242A CA 2448242 C CA2448242 C CA 2448242C
Authority
CA
Canada
Prior art keywords
acetyl
carnitine
acid
treatment
pain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2448242A
Other languages
English (en)
French (fr)
Other versions
CA2448242A1 (en
Inventor
Menotti Calvani
Luigi Mosconi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sigma Tau Industrie Farmaceutiche Riunite SpA
Original Assignee
Sigma Tau Industrie Farmaceutiche Riunite SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Industrie Farmaceutiche Riunite SpA filed Critical Sigma Tau Industrie Farmaceutiche Riunite SpA
Publication of CA2448242A1 publication Critical patent/CA2448242A1/en
Application granted granted Critical
Publication of CA2448242C publication Critical patent/CA2448242C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/221—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having an amino group, e.g. acetylcholine, acetylcarnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Emergency Medicine (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
CA2448242A 2001-05-29 2002-05-24 Use of acetyl l-carnitine for the preparation of a medication for the preventive therapy for pain Expired - Fee Related CA2448242C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT2001RM000293A ITRM20010293A1 (it) 2001-05-29 2001-05-29 Uso della acetil-l-carnetina per la preparazione di un medicamento per la prevenzione del dolore.
ITRM01A000293 2001-05-29
PCT/IT2002/000336 WO2002096409A1 (en) 2001-05-29 2002-05-24 Use of acetyl l-carnitine for the preparation of a medication for the preventive therapy for pain

Publications (2)

Publication Number Publication Date
CA2448242A1 CA2448242A1 (en) 2002-12-05
CA2448242C true CA2448242C (en) 2011-01-11

Family

ID=11455557

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2448242A Expired - Fee Related CA2448242C (en) 2001-05-29 2002-05-24 Use of acetyl l-carnitine for the preparation of a medication for the preventive therapy for pain

Country Status (18)

Country Link
US (2) US20040152781A1 (enExample)
EP (1) EP1399141B1 (enExample)
JP (1) JP4287660B2 (enExample)
KR (1) KR100873748B1 (enExample)
AT (1) ATE374021T1 (enExample)
CA (1) CA2448242C (enExample)
CY (1) CY1107037T1 (enExample)
CZ (1) CZ20033220A3 (enExample)
DE (1) DE60222662T2 (enExample)
DK (1) DK1399141T3 (enExample)
ES (1) ES2290292T3 (enExample)
HU (1) HUP0401294A3 (enExample)
IT (1) ITRM20010293A1 (enExample)
MX (1) MXPA03010919A (enExample)
PL (1) PL367616A1 (enExample)
PT (1) PT1399141E (enExample)
SK (1) SK287559B6 (enExample)
WO (1) WO2002096409A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITRM20040606A1 (it) * 2004-12-13 2005-03-13 Sigma Tau Ind Farmaceuti Uso della acetil l-carnitina per il trattamento della sindrome fibromialgica.
JP5685362B2 (ja) * 2005-04-26 2015-03-18 シグマ−タウ・インドゥストリエ・ファルマチェウチケ・リウニテ・ソシエタ・ペル・アチオニＳｉｇｍａ−Ｔａｕ Ｉｎｄｕｓｔｒｉｅ Ｆａｒｍａｃｅｕｔｉｃｈｅ Ｒｉｕｎｉｔｅ Ｓｏｃｉｅｔａ Ｐｅｒ Ａｚｉｏｎｉ 有痛性末梢糖尿病性神経障害の予防のためのアセチルｌ−カルニチン
IT202200022437A1 (it) 2022-11-02 2024-05-02 Chiesi Italia S P A Composizione farmaceutica comprendente l-acetilcarnitina e beta-cariofillene

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0150688B1 (en) * 1983-12-28 1987-04-22 Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. Salts of l-carnitine and alkanoyl l-carnitines and process for preparing same
IT1196564B (it) * 1986-08-04 1988-11-16 Sigma Tau Ind Farmaceuti Impiego di acetil l-carnitina nel trattamento terapeutico delle neuropatie periferiche
IT1277147B1 (it) * 1995-01-20 1997-11-04 Sigma Tau Ind Farmaceuti Uso della carnitina e i suoi derivati per ridurre gli effetti tossici della ciclosporina-a e di altri farmaci immunosoppressivi.

Also Published As

Publication number Publication date
DK1399141T3 (da) 2008-01-02
SK15842003A3 (sk) 2004-06-08
DE60222662T2 (de) 2008-06-26
CY1107037T1 (el) 2012-09-26
PT1399141E (pt) 2007-11-16
HUP0401294A2 (hu) 2004-12-28
ITRM20010293A1 (it) 2002-11-29
EP1399141A1 (en) 2004-03-24
WO2002096409A1 (en) 2002-12-05
JP4287660B2 (ja) 2009-07-01
PL367616A1 (en) 2005-03-07
DE60222662D1 (de) 2007-11-08
JP2004532865A (ja) 2004-10-28
ES2290292T3 (es) 2008-02-16
SK287559B6 (sk) 2011-02-04
KR100873748B1 (ko) 2008-12-12
ITRM20010293A0 (it) 2001-05-29
CA2448242A1 (en) 2002-12-05
HUP0401294A3 (en) 2008-04-28
CZ20033220A3 (en) 2004-06-16
ATE374021T1 (de) 2007-10-15
US20040152781A1 (en) 2004-08-05
KR20040003030A (ko) 2004-01-07
US20090062388A1 (en) 2009-03-05
MXPA03010919A (es) 2004-02-27
EP1399141B1 (en) 2007-09-26

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