KR100742316B1 - 바이칼레인을 유효성분으로 포함하는 알코올―유도신경독성의 치료 또는 예방용 조성물 - Google Patents
바이칼레인을 유효성분으로 포함하는 알코올―유도신경독성의 치료 또는 예방용 조성물 Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/03—Organic compounds
- A23L29/035—Organic compounds containing oxygen as heteroatom
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2200/00—Function of food ingredients
- A23V2200/30—Foods, ingredients or supplements having a functional effect on health
- A23V2200/334—Foods, ingredients or supplements having a functional effect on health treating the effects of consuming alcohol, narcotics or other addictive behavior, e.g. treating hangover or reducing blood alcohol levels
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- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
Claims (8)
- 삭제
- 바이칼레인 (baicalein)을 유효성분으로 포함하는 알코올-유도 신경독성에 의한 두뇌 또는 인지 기능의 감소를 개선하기 위한 기능성 식품 조성물.
- 제 2 항에 있어서, 상기 알코올은 에탄올인 것을 특징으로 하는 조성물.
- 제 2 항에 있어서, 상기 바이칼레인은 알코올에 의해 유도된 p53 단백질의 발현 증가를 하향 조절 (down-regulation)함으로써 알코올-유도 신경독성을 감소시키는 것을 특징으로 하는 조성물.
- 제 2 항에 있어서, 상기 바이칼레인은 알코올에 의해 유도된 미토콘드리아 막 전위차 감소를 증가시킴으로써 알코올-유도 신경독성을 감소시키는 것을 특징으로 하는 조성물.
- 제 2 항에 있어서, 상기 바이칼레인은 알코올에 의해 유도된 카스파아제 (caspase) 활성 증가를 감소시킴으로써 알코올-유도 신경독성을 감소시키는 것을 특징으로 하는 조성물.
- 제 2 항에 있어서, 상기 바이칼레인은 알코올에 의해 유도된 신경세포의 아폽토시스 (apoptosis)를 억제시킴으로써 알코올-유도 신경독성을 감소시키는 것을 특징으로 하는 조성물.
- 제 2 항에 있어서, 상기 두뇌 또는 인지 기능은 학습능력 또는 기억력인 것을 특징으로 하는 조성물.
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KR1020050069210A KR100742316B1 (ko) | 2005-07-29 | 2005-07-29 | 바이칼레인을 유효성분으로 포함하는 알코올―유도신경독성의 치료 또는 예방용 조성물 |
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KR101339984B1 (ko) * | 2012-02-07 | 2013-12-10 | 부산대학교 산학협력단 | 바이칼린을 유효성분으로 포함하는 방사선 노출에 의한 해마신경재생성 손상 방지용 약학적 조성물 |
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CN116832030A (zh) * | 2023-08-07 | 2023-10-03 | 首都医科大学附属北京妇产医院 | 黄芩素在制备治疗pcos卵巢功能障碍相关药物中的应用 |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
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JPH01163120A (ja) * | 1987-12-21 | 1989-06-27 | Tsumura & Co | 抗レトロウイルス剤 |
JPH02101013A (ja) * | 1988-10-11 | 1990-04-12 | Daicel Chem Ind Ltd | ウイルス・ゲノム不活化剤 |
JPH02193930A (ja) * | 1989-01-19 | 1990-07-31 | Tsumura & Co | ラジカル消去剤 |
JPH05331061A (ja) * | 1992-06-01 | 1993-12-14 | Tsumura & Co | アポトーシス誘起剤 |
JPH07196490A (ja) * | 1993-12-28 | 1995-08-01 | Terumo Corp | 癌転移抑制剤 |
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Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH01163120A (ja) * | 1987-12-21 | 1989-06-27 | Tsumura & Co | 抗レトロウイルス剤 |
JPH02101013A (ja) * | 1988-10-11 | 1990-04-12 | Daicel Chem Ind Ltd | ウイルス・ゲノム不活化剤 |
JPH02193930A (ja) * | 1989-01-19 | 1990-07-31 | Tsumura & Co | ラジカル消去剤 |
JPH05331061A (ja) * | 1992-06-01 | 1993-12-14 | Tsumura & Co | アポトーシス誘起剤 |
JPH07196490A (ja) * | 1993-12-28 | 1995-08-01 | Terumo Corp | 癌転移抑制剤 |
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KR101339984B1 (ko) * | 2012-02-07 | 2013-12-10 | 부산대학교 산학협력단 | 바이칼린을 유효성분으로 포함하는 방사선 노출에 의한 해마신경재생성 손상 방지용 약학적 조성물 |
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