KR100663969B1 - The production method for distillate including Chrysanthemum, Pinanceae, Acanthopanax and Rhamnaceae and the distillate thereof - Google Patents
The production method for distillate including Chrysanthemum, Pinanceae, Acanthopanax and Rhamnaceae and the distillate thereof Download PDFInfo
- Publication number
- KR100663969B1 KR100663969B1 KR1020040104316A KR20040104316A KR100663969B1 KR 100663969 B1 KR100663969 B1 KR 100663969B1 KR 1020040104316 A KR1020040104316 A KR 1020040104316A KR 20040104316 A KR20040104316 A KR 20040104316A KR 100663969 B1 KR100663969 B1 KR 100663969B1
- Authority
- KR
- South Korea
- Prior art keywords
- leaves
- distillate
- pharmacological
- extract
- pine needles
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 13
- 235000007516 Chrysanthemum Nutrition 0.000 title abstract description 7
- 241000723353 Chrysanthemum Species 0.000 title abstract 2
- 241000219100 Rhamnaceae Species 0.000 title 1
- 241000196324 Embryophyta Species 0.000 claims abstract description 45
- 239000000284 extract Substances 0.000 claims abstract description 32
- 235000011613 Pinus brutia Nutrition 0.000 claims abstract description 31
- 235000008331 Pinus X rigitaeda Nutrition 0.000 claims abstract description 29
- 241000018646 Pinus brutia Species 0.000 claims abstract description 29
- 235000008495 Chrysanthemum leucanthemum Nutrition 0.000 claims abstract description 23
- 244000035851 Chrysanthemum leucanthemum Species 0.000 claims abstract description 23
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 20
- 238000000034 method Methods 0.000 claims abstract description 14
- 239000008213 purified water Substances 0.000 claims abstract description 8
- 230000000144 pharmacologic effect Effects 0.000 claims description 60
- 239000011550 stock solution Substances 0.000 claims description 16
- 239000012141 concentrate Substances 0.000 claims description 13
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 10
- 244000305267 Quercus macrolepis Species 0.000 claims description 9
- 239000000243 solution Substances 0.000 claims description 9
- 235000019441 ethanol Nutrition 0.000 claims description 5
- 238000001914 filtration Methods 0.000 claims description 4
- 238000003756 stirring Methods 0.000 claims description 4
- 238000002156 mixing Methods 0.000 claims description 3
- 230000001954 sterilising effect Effects 0.000 claims description 3
- 235000009917 Crataegus X brevipes Nutrition 0.000 claims description 2
- 235000013204 Crataegus X haemacarpa Nutrition 0.000 claims description 2
- 235000009685 Crataegus X maligna Nutrition 0.000 claims description 2
- 235000009444 Crataegus X rubrocarnea Nutrition 0.000 claims description 2
- 235000009486 Crataegus bullatus Nutrition 0.000 claims description 2
- 235000017181 Crataegus chrysocarpa Nutrition 0.000 claims description 2
- 235000009682 Crataegus limnophila Nutrition 0.000 claims description 2
- 240000000171 Crataegus monogyna Species 0.000 claims description 2
- 235000004423 Crataegus monogyna Nutrition 0.000 claims description 2
- 235000002313 Crataegus paludosa Nutrition 0.000 claims description 2
- 235000009840 Crataegus x incaedua Nutrition 0.000 claims description 2
- 240000005979 Hordeum vulgare Species 0.000 claims 1
- 235000007340 Hordeum vulgare Nutrition 0.000 claims 1
- 238000001816 cooling Methods 0.000 claims 1
- 238000010438 heat treatment Methods 0.000 claims 1
- 241000411851 herbal medicine Species 0.000 claims 1
- 238000004806 packaging method and process Methods 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
- 238000004659 sterilization and disinfection Methods 0.000 claims 1
- 241000588724 Escherichia coli Species 0.000 abstract description 11
- 230000000694 effects Effects 0.000 abstract description 10
- QZAYGJVTTNCVMB-UHFFFAOYSA-N serotonin Chemical compound C1=C(O)C=C2C(CCN)=CNC2=C1 QZAYGJVTTNCVMB-UHFFFAOYSA-N 0.000 abstract description 10
- 241000589517 Pseudomonas aeruginosa Species 0.000 abstract description 9
- NTYJJOPFIAHURM-UHFFFAOYSA-N Histamine Chemical compound NCCC1=CN=CN1 NTYJJOPFIAHURM-UHFFFAOYSA-N 0.000 abstract description 6
- 208000006673 asthma Diseases 0.000 abstract description 6
- 150000002500 ions Chemical class 0.000 abstract description 5
- 235000008216 herbs Nutrition 0.000 abstract description 4
- 229940076279 serotonin Drugs 0.000 abstract description 4
- 208000019695 Migraine disease Diseases 0.000 abstract description 3
- 239000000712 neurohormone Substances 0.000 abstract description 3
- 208000023504 respiratory system disease Diseases 0.000 abstract description 3
- 206010027603 Migraine headaches Diseases 0.000 abstract description 2
- 240000001439 Opuntia Species 0.000 abstract description 2
- 235000013389 Opuntia humifusa var. humifusa Nutrition 0.000 abstract description 2
- 238000000605 extraction Methods 0.000 abstract 1
- 102000008434 neuropeptide hormone activity proteins Human genes 0.000 abstract 1
- 108040002669 neuropeptide hormone activity proteins Proteins 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 238000000638 solvent extraction Methods 0.000 abstract 1
- 238000003809 water extraction Methods 0.000 abstract 1
- 238000012360 testing method Methods 0.000 description 25
- 150000001450 anions Chemical class 0.000 description 10
- 238000004821 distillation Methods 0.000 description 10
- 235000013361 beverage Nutrition 0.000 description 7
- 238000002360 preparation method Methods 0.000 description 7
- 230000008569 process Effects 0.000 description 7
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 6
- 230000001953 sensory effect Effects 0.000 description 6
- 241000894006 Bacteria Species 0.000 description 5
- 230000000844 anti-bacterial effect Effects 0.000 description 5
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 5
- 239000000706 filtrate Substances 0.000 description 4
- 239000012528 membrane Substances 0.000 description 4
- 229920001817 Agar Polymers 0.000 description 3
- 235000006667 Aleurites moluccana Nutrition 0.000 description 3
- 235000003840 Amygdalus nana Nutrition 0.000 description 3
- 244000296825 Amygdalus nana Species 0.000 description 3
- 244000189548 Chrysanthemum x morifolium Species 0.000 description 3
- 235000009496 Juglans regia Nutrition 0.000 description 3
- 240000007049 Juglans regia Species 0.000 description 3
- 206010028980 Neoplasm Diseases 0.000 description 3
- 235000011432 Prunus Nutrition 0.000 description 3
- 239000002253 acid Substances 0.000 description 3
- 239000008272 agar Substances 0.000 description 3
- 230000000845 anti-microbial effect Effects 0.000 description 3
- 239000003638 chemical reducing agent Substances 0.000 description 3
- 235000020971 citrus fruits Nutrition 0.000 description 3
- 238000009833 condensation Methods 0.000 description 3
- 230000005494 condensation Effects 0.000 description 3
- 229930190029 eleutheroside Natural products 0.000 description 3
- 239000008769 eleutheroside Substances 0.000 description 3
- 239000002054 inoculum Substances 0.000 description 3
- 235000014774 prunus Nutrition 0.000 description 3
- 230000005855 radiation Effects 0.000 description 3
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 description 2
- 241000208340 Araliaceae Species 0.000 description 2
- 241000269837 Artemisia dubia Species 0.000 description 2
- 235000003261 Artemisia vulgaris Nutrition 0.000 description 2
- 235000003255 Carthamus tinctorius Nutrition 0.000 description 2
- 244000020518 Carthamus tinctorius Species 0.000 description 2
- 240000005250 Chrysanthemum indicum Species 0.000 description 2
- 241000207199 Citrus Species 0.000 description 2
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 2
- 102000006771 Gonadotropins Human genes 0.000 description 2
- 108010086677 Gonadotropins Proteins 0.000 description 2
- 235000008584 Hovenia dulcis Nutrition 0.000 description 2
- 244000010000 Hovenia dulcis Species 0.000 description 2
- UPYKUZBSLRQECL-UKMVMLAPSA-N Lycopene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1C(=C)CCCC1(C)C)C=CC=C(/C)C=CC2C(=C)CCCC2(C)C UPYKUZBSLRQECL-UKMVMLAPSA-N 0.000 description 2
- 241000218641 Pinaceae Species 0.000 description 2
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 description 2
- 229930003268 Vitamin C Natural products 0.000 description 2
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 description 2
- 230000000840 anti-viral effect Effects 0.000 description 2
- HJJPJSXJAXAIPN-UHFFFAOYSA-N arecoline Chemical compound COC(=O)C1=CCCN(C)C1 HJJPJSXJAXAIPN-UHFFFAOYSA-N 0.000 description 2
- 230000036772 blood pressure Effects 0.000 description 2
- 235000012206 bottled water Nutrition 0.000 description 2
- 201000011510 cancer Diseases 0.000 description 2
- 150000001746 carotenes Chemical class 0.000 description 2
- 235000005473 carotenes Nutrition 0.000 description 2
- 206010012601 diabetes mellitus Diseases 0.000 description 2
- 235000013399 edible fruits Nutrition 0.000 description 2
- 238000011156 evaluation Methods 0.000 description 2
- 239000008103 glucose Substances 0.000 description 2
- 239000002622 gonadotropin Substances 0.000 description 2
- 230000002401 inhibitory effect Effects 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 239000003921 oil Substances 0.000 description 2
- 235000015205 orange juice Nutrition 0.000 description 2
- 230000009467 reduction Effects 0.000 description 2
- 235000018553 tannin Nutrition 0.000 description 2
- 239000001648 tannin Substances 0.000 description 2
- 229920001864 tannin Polymers 0.000 description 2
- 235000019155 vitamin A Nutrition 0.000 description 2
- 239000011719 vitamin A Substances 0.000 description 2
- NCYCYZXNIZJOKI-UHFFFAOYSA-N vitamin A aldehyde Natural products O=CC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C NCYCYZXNIZJOKI-UHFFFAOYSA-N 0.000 description 2
- 235000019154 vitamin C Nutrition 0.000 description 2
- 239000011718 vitamin C Substances 0.000 description 2
- 229940045997 vitamin a Drugs 0.000 description 2
- 239000000341 volatile oil Substances 0.000 description 2
- BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 description 1
- CWVRJTMFETXNAD-FWCWNIRPSA-N 3-O-Caffeoylquinic acid Natural products O[C@H]1[C@@H](O)C[C@@](O)(C(O)=O)C[C@H]1OC(=O)\C=C\C1=CC=C(O)C(O)=C1 CWVRJTMFETXNAD-FWCWNIRPSA-N 0.000 description 1
- 241000332371 Abutilon x hybridum Species 0.000 description 1
- 229930024421 Adenine Natural products 0.000 description 1
- GFFGJBXGBJISGV-UHFFFAOYSA-N Adenine Chemical compound NC1=NC=NC2=C1N=CN2 GFFGJBXGBJISGV-UHFFFAOYSA-N 0.000 description 1
- KMOUJOKENFFTPU-UHFFFAOYSA-N Apigenin-7-glucosid Natural products OC1C(O)C(O)C(CO)OC1OC1=CC(O)=C2C(=O)C=C(C=3C=CC(O)=CC=3)OC2=C1 KMOUJOKENFFTPU-UHFFFAOYSA-N 0.000 description 1
- 241001061264 Astragalus Species 0.000 description 1
- 206010006187 Breast cancer Diseases 0.000 description 1
- 208000026310 Breast neoplasm Diseases 0.000 description 1
- 235000004936 Bromus mango Nutrition 0.000 description 1
- PZIRUHCJZBGLDY-UHFFFAOYSA-N Caffeoylquinic acid Natural products CC(CCC(=O)C(C)C1C(=O)CC2C3CC(O)C4CC(O)CCC4(C)C3CCC12C)C(=O)O PZIRUHCJZBGLDY-UHFFFAOYSA-N 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- 241000238366 Cephalopoda Species 0.000 description 1
- 240000000425 Chaenomeles speciosa Species 0.000 description 1
- 235000005078 Chaenomeles speciosa Nutrition 0.000 description 1
- 241000132536 Cirsium Species 0.000 description 1
- 244000301850 Cupressus sempervirens Species 0.000 description 1
- 241000588722 Escherichia Species 0.000 description 1
- 235000014066 European mistletoe Nutrition 0.000 description 1
- 235000004204 Foeniculum vulgare Nutrition 0.000 description 1
- 240000006927 Foeniculum vulgare Species 0.000 description 1
- 238000005033 Fourier transform infrared spectroscopy Methods 0.000 description 1
- 235000016623 Fragaria vesca Nutrition 0.000 description 1
- 240000009088 Fragaria x ananassa Species 0.000 description 1
- 235000011363 Fragaria x ananassa Nutrition 0.000 description 1
- 240000004670 Glycyrrhiza echinata Species 0.000 description 1
- 235000001453 Glycyrrhiza echinata Nutrition 0.000 description 1
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 description 1
- 235000017382 Glycyrrhiza lepidota Nutrition 0.000 description 1
- 240000002045 Guettarda speciosa Species 0.000 description 1
- 235000001287 Guettarda speciosa Nutrition 0.000 description 1
- 240000000950 Hippophae rhamnoides Species 0.000 description 1
- 235000003145 Hippophae rhamnoides Nutrition 0.000 description 1
- 208000022994 Isolated optic neuritis Diseases 0.000 description 1
- 241000218652 Larix Species 0.000 description 1
- 235000005590 Larix decidua Nutrition 0.000 description 1
- 235000014826 Mangifera indica Nutrition 0.000 description 1
- 240000007228 Mangifera indica Species 0.000 description 1
- CWVRJTMFETXNAD-KLZCAUPSSA-N Neochlorogenin-saeure Natural products O[C@H]1C[C@@](O)(C[C@@H](OC(=O)C=Cc2ccc(O)c(O)c2)[C@@H]1O)C(=O)O CWVRJTMFETXNAD-KLZCAUPSSA-N 0.000 description 1
- 235000017831 Pseudocydonia sinensis Nutrition 0.000 description 1
- 244000152640 Rhipsalis cassutha Species 0.000 description 1
- 235000012300 Rhipsalis cassutha Nutrition 0.000 description 1
- 240000006079 Schisandra chinensis Species 0.000 description 1
- 235000008422 Schisandra chinensis Nutrition 0.000 description 1
- 206010039897 Sedation Diseases 0.000 description 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 1
- 240000009241 Smilax aspera Species 0.000 description 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
- 235000009184 Spondias indica Nutrition 0.000 description 1
- 208000005718 Stomach Neoplasms Diseases 0.000 description 1
- 240000001949 Taraxacum officinale Species 0.000 description 1
- 235000005187 Taraxacum officinale ssp. officinale Nutrition 0.000 description 1
- 235000019714 Triticale Nutrition 0.000 description 1
- 244000172533 Viola sororia Species 0.000 description 1
- 229930003270 Vitamin B Natural products 0.000 description 1
- 229930003448 Vitamin K Natural products 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 229960000643 adenine Drugs 0.000 description 1
- OENHQHLEOONYIE-UKMVMLAPSA-N all-trans beta-carotene Natural products CC=1CCCC(C)(C)C=1/C=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C OENHQHLEOONYIE-UKMVMLAPSA-N 0.000 description 1
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 description 1
- 230000001775 anti-pathogenic effect Effects 0.000 description 1
- 230000003356 anti-rheumatic effect Effects 0.000 description 1
- 230000002180 anti-stress Effects 0.000 description 1
- 239000003435 antirheumatic agent Substances 0.000 description 1
- XADJWCRESPGUTB-UHFFFAOYSA-N apigenin Natural products C1=CC(O)=CC=C1C1=CC(=O)C2=CC(O)=C(O)C=C2O1 XADJWCRESPGUTB-UHFFFAOYSA-N 0.000 description 1
- KZNIFHPLKGYRTM-UHFFFAOYSA-N apigenin Chemical compound C1=CC(O)=CC=C1C1=CC(=O)C2=C(O)C=C(O)C=C2O1 KZNIFHPLKGYRTM-UHFFFAOYSA-N 0.000 description 1
- 229940117893 apigenin Drugs 0.000 description 1
- 235000008714 apigenin Nutrition 0.000 description 1
- KMOUJOKENFFTPU-QNDFHXLGSA-N apigenin 7-O-beta-D-glucoside Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=CC(O)=C2C(=O)C=C(C=3C=CC(O)=CC=3)OC2=C1 KMOUJOKENFFTPU-QNDFHXLGSA-N 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- 235000010323 ascorbic acid Nutrition 0.000 description 1
- 239000011668 ascorbic acid Substances 0.000 description 1
- 229960005070 ascorbic acid Drugs 0.000 description 1
- 235000006533 astragalus Nutrition 0.000 description 1
- 210000000467 autonomic pathway Anatomy 0.000 description 1
- 230000003385 bacteriostatic effect Effects 0.000 description 1
- 235000013527 bean curd Nutrition 0.000 description 1
- 230000003796 beauty Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 235000013734 beta-carotene Nutrition 0.000 description 1
- TUPZEYHYWIEDIH-WAIFQNFQSA-N beta-carotene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C)C=CC=C(/C)C=CC2=CCCCC2(C)C TUPZEYHYWIEDIH-WAIFQNFQSA-N 0.000 description 1
- 239000011648 beta-carotene Substances 0.000 description 1
- 229960002747 betacarotene Drugs 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 239000012267 brine Substances 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 229940074393 chlorogenic acid Drugs 0.000 description 1
- CWVRJTMFETXNAD-JUHZACGLSA-N chlorogenic acid Chemical compound O[C@@H]1[C@H](O)C[C@@](O)(C(O)=O)C[C@H]1OC(=O)\C=C\C1=CC=C(O)C(O)=C1 CWVRJTMFETXNAD-JUHZACGLSA-N 0.000 description 1
- FFQSDFBBSXGVKF-KHSQJDLVSA-N chlorogenic acid Natural products O[C@@H]1C[C@](O)(C[C@@H](CC(=O)C=Cc2ccc(O)c(O)c2)[C@@H]1O)C(=O)O FFQSDFBBSXGVKF-KHSQJDLVSA-N 0.000 description 1
- 235000001368 chlorogenic acid Nutrition 0.000 description 1
- BMRSEYFENKXDIS-KLZCAUPSSA-N cis-3-O-p-coumaroylquinic acid Natural products O[C@H]1C[C@@](O)(C[C@@H](OC(=O)C=Cc2ccc(O)cc2)[C@@H]1O)C(=O)O BMRSEYFENKXDIS-KLZCAUPSSA-N 0.000 description 1
- 230000006837 decompression Effects 0.000 description 1
- 238000001784 detoxification Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 239000000839 emulsion Substances 0.000 description 1
- 230000008029 eradication Effects 0.000 description 1
- 229930003935 flavonoid Natural products 0.000 description 1
- 150000002215 flavonoids Chemical class 0.000 description 1
- 235000017173 flavonoids Nutrition 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 235000015203 fruit juice Nutrition 0.000 description 1
- 206010017758 gastric cancer Diseases 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 230000004153 glucose metabolism Effects 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000036737 immune function Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000011081 inoculation Methods 0.000 description 1
- 206010022437 insomnia Diseases 0.000 description 1
- 229940010454 licorice Drugs 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 201000007270 liver cancer Diseases 0.000 description 1
- 230000003908 liver function Effects 0.000 description 1
- 208000014018 liver neoplasm Diseases 0.000 description 1
- 235000011090 malic acid Nutrition 0.000 description 1
- 239000001630 malic acid Substances 0.000 description 1
- 206010027175 memory impairment Diseases 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- 239000011259 mixed solution Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000004570 mortar (masonry) Substances 0.000 description 1
- 235000008486 nectar Nutrition 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 235000019629 palatability Nutrition 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- SHUZOJHMOBOZST-UHFFFAOYSA-N phylloquinone Natural products CC(C)CCCCC(C)CCC(C)CCCC(=CCC1=C(C)C(=O)c2ccccc2C1=O)C SHUZOJHMOBOZST-UHFFFAOYSA-N 0.000 description 1
- 230000035479 physiological effects, processes and functions Effects 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 230000007096 poisonous effect Effects 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 238000010791 quenching Methods 0.000 description 1
- 230000000171 quenching effect Effects 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000036280 sedation Effects 0.000 description 1
- 239000010865 sewage Substances 0.000 description 1
- 210000000813 small intestine Anatomy 0.000 description 1
- HPALAKNZSZLMCH-UHFFFAOYSA-M sodium;chloride;hydrate Chemical compound O.[Na+].[Cl-] HPALAKNZSZLMCH-UHFFFAOYSA-M 0.000 description 1
- 235000013322 soy milk Nutrition 0.000 description 1
- -1 stachydrin Chemical compound 0.000 description 1
- 230000007103 stamina Effects 0.000 description 1
- 238000010025 steaming Methods 0.000 description 1
- 201000011549 stomach cancer Diseases 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 210000004233 talus Anatomy 0.000 description 1
- HUTYZQWCTWWXND-NCTFTGAASA-N taraxasterol Natural products C[C@H]1[C@H]2C3=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]4(C)[C@]3(C)C[C@H](O)[C@@]2(C)CCC1=C HUTYZQWCTWWXND-NCTFTGAASA-N 0.000 description 1
- JZRWCGZRTZMZEH-UHFFFAOYSA-N thiamine Chemical compound CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N JZRWCGZRTZMZEH-UHFFFAOYSA-N 0.000 description 1
- 230000035922 thirst Effects 0.000 description 1
- 239000012137 tryptone Substances 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
- 235000019156 vitamin B Nutrition 0.000 description 1
- 239000011720 vitamin B Substances 0.000 description 1
- 235000019168 vitamin K Nutrition 0.000 description 1
- 239000011712 vitamin K Substances 0.000 description 1
- 150000003721 vitamin K derivatives Chemical class 0.000 description 1
- 229940046010 vitamin k Drugs 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 241000228158 x Triticosecale Species 0.000 description 1
- OENHQHLEOONYIE-JLTXGRSLSA-N β-Carotene Chemical compound CC=1CCCC(C)(C)C=1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C OENHQHLEOONYIE-JLTXGRSLSA-N 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/38—Other non-alcoholic beverages
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L5/00—Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
- A23L5/51—Concentration
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2200/00—Function of food ingredients
- A23V2200/30—Foods, ingredients or supplements having a functional effect on health
- A23V2200/314—Foods, ingredients or supplements having a functional effect on health having an effect on lung or respiratory system
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2250/00—Food ingredients
- A23V2250/20—Natural extracts
- A23V2250/21—Plant extracts
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2300/00—Processes
- A23V2300/14—Extraction
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2300/00—Processes
- A23V2300/24—Heat, thermal treatment
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2300/00—Processes
- A23V2300/50—Concentrating, enriching or enhancing in functional factors
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Botany (AREA)
- Mycology (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
본 발명은 들국화잎, 솔잎, 가시오가피 및 헛개나무잎으로 부터 추출한 약리성식물 증류액을 함유한 약수물의 제조방법 및 상기 방법으로 제조된 약수물에 관한 것이다.The present invention relates to a method for producing a medicinal herb containing medicinal plant distillate extracted from wild chrysanthemum leaves, pine needles, thorny scabbard and bark leaf and the medicinal herb prepared by the above method.
본 발명은 들국화의 잎, 솔잎, 가시오가피의 줄기 및 잎, 헛개나무의 잎을 열수추출, 유기용매추출, 잔류물 추출한 다음, 상기 추출물들을 혼합, 여과 및 증류의 공정을 거쳐서 약리성식물 증류액을 제조하여 정제수에 첨가함으로써, 대장균과 녹농균에 대해 저항력을 가지는 효과가 있다.According to the present invention, the leaves of pine chrysanthemum, pine needles, stems and leaves of thorny opiaceae, leaves of huts, hot water extraction, organic solvent extraction, residue extraction, and then the extracts are mixed, filtered and distilled to obtain medicinal plant distillate. By preparing and adding to purified water, there is an effect having resistance to E. coli and Pseudomonas aeruginosa.
또한 본 발명의 약수물은 음이온 발생이 현저하여 알파(α)파의 활동을 증가시켜 천식과 편두통을 완화시켜 주고 천식과 같은 호흡기 질환을 일으키는 신경호르몬인 세로토닌(Serotonine)과 자유 히스타민(Free Histamine)을 억제하는 효과가 있다.In addition, the medicinal herbs of the present invention have a significant negative ions to increase the activity of the alpha (α) wave to relieve asthma and migraine headaches, serotonin (Serotonine) and free histamine (Free Histamine), a neurohormone that causes respiratory diseases such as asthma It has a suppressing effect.
약리성식물 증류액, 들국화, 솔잎, 가시오가피, 헛개나무Medicinal Plant Distillate, Wild Chrysanthemum, Pine Needle, Prickly Pear
Description
도 1은 본 발명에 따른 약리성식물 증류액의 제조공정도이다.1 is a manufacturing process of the pharmacological plant distillate according to the present invention.
도 2는 본 발명에 따른 약리성식물 증류액을 함유한 약수물의 제조공정도이다.Figure 2 is a manufacturing process of the medicinal herbs containing pharmacological plant distillate according to the present invention.
도 3은 본 발명에 따른 약리성식물 증류액의 녹농균에 대한 저항력을 실험한 결과이다.3 is a test result of resistance to Pseudomonas aeruginosa of the pharmacological distillate of the present invention.
도 4는 본 발명에 따른 약리성식물 증류액의 대장균에 대한 저항력을 실험한 결과이다.Figure 4 is a test result of the resistance to E. coli of the pharmacological distillate of the present invention.
본 발명은 들국화, 솔잎, 가시오가피, 헛개나무잎을 포함하는 약리성식물 증류액을 함유한 약수물의 제조방법 및 상기 방법으로 제조한 약수물에 관한 것이다.The present invention relates to a method for producing a medicinal herb containing medicinal plant distillate, including wild chrysanthemum, pine needles, thorny stems, bark leaves, and medicinal herbs prepared by the above method.
최근 2000년에 들어서면서 음료시장의 화두는 단연'천연'이었다. 꾸준히 이 어져 온 건강음료 트렌드에 힘입어 망고, 감귤 등 과일쥬스와 두유 등 천연소재로 만든 이른바 '천연음료'가 소비자들의 많은 사랑을 받았다.In 2000, the topic of the beverage market was 'natural'. The so-called 'natural drinks' made of natural materials, such as fruit juices such as mango and citrus fruits and soy milk, have been loved by consumers thanks to the continuous trend of healthy drinks.
100% 일반 오렌지쥬스 시장의 마이너스 성장은 기능성, 냉장유통쥬스 외 100% 일반오렌지쥬스 시장이 점차 감귤쥬스와 기타 쥬스로 대체되고 있음을 의미한다.Negative growth in the 100% normal orange juice market means that the market for 100% general orange juice in addition to functional and refrigerated distribution juice is gradually being replaced by citrus juice and other juices.
이처럼 감귤쥬스가 많은 사랑을 받고 있는 것은 오렌지와는 달리 우리에게 친숙한 토종 농산물인데다 오렌지보다 신맛은 적고 달콤하기 때문이다. 또한 비타민 C가 풍부해 피부미용과 감기예방 등에 효과가 있으며 비타민 A의 모체인 베타카로틴이 풍부하여 암예방에 도움을 준다.Like oranges, citrus juices are loved a lot because, unlike oranges, they are familiar to us, and they are less sour and sweeter than oranges. In addition, it is rich in vitamin C, which is effective for skin beauty and cold prevention, and is rich in beta-carotene, the mother of vitamin A, to help prevent cancer.
이와 같은 추세로 살펴보면 음료수는 단순한 갈증해소차원에서 벗어나 인체생리에도 영향을 미치는 특수한 기능성이 강조되는 추세를 나타내면서 음료대기업과 중소업체들이 앞다투어 시장경쟁에 뛰어들고 있고, 과실음료, 기능성 음료, 전통음료, 생수 등의 새로운 시장의 창출로 신규업체의 참여가 급격히 증가하여 시장경쟁이 치열해지고 있으나, 생수 등의 경우 대장균 및 기타 병원균에 쉽게 노출되어 많은 문제점을 낳고 있다.As the trend shows, beverages are not only quenching thirst but special functionalities that affect human physiology are emphasized, and large conglomerates and small and medium-sized companies are competing in the market competition. Fruit drinks, functional drinks, traditional drinks, Market competition is intensifying due to the rapid increase of new companies' participation due to the creation of new markets such as bottled water, but bottled water is easily exposed to Escherichia coli and other pathogens, causing many problems.
상기 전술한 문제점을 해결하기 위한 본 발명의 목적은 들국화잎, 솔잎, 가시오가피, 헛개나무잎을 포함하는 약리성식물 증류액을 함유한 약수물의 제조방법 및 약수물을 제공하는데 있다.An object of the present invention for solving the above-mentioned problems is to provide a method for producing a medicinal herb containing medicinal plant distillate, including wild chrysanthemum leaves, pine needles, thorny scabbard, bark leaf.
상기 기술적 과제를 해결하기 위한 본 발명은 들국화잎(Chrysanthemum), 솔잎(Pinaceae), 가시오가피(Araliaceae), 헛개나무(Hovenia Dulcis)잎을 포함하는 약리성식물 증류액을 함유한 약수물의 제조방법 및 약수물에 관한 것이다.The present invention for solving the above technical problem is a method and preparation of medicinal herbs containing medicinal plant distillate, including wild chrysanthemum leaves ( Chrysanthemum ), pine needles ( Pinaceae ), prickly pear ( Araliaceae ), leaf of Hovenia Dulcis It is about.
국화과(Chrysanthemum)의 들국화잎은 콜린, 스타키드린, 아데닌, 비타민 A, 비타민 B1, 아피제니닌(apigenin), 아피게트린(apigetrin), 16-β-하이드록시-3-푸세도타엑스테롤(16-β-Hydroxy-3-pseudotaraxasterol), 클로로젠닉산(Chlorogenic acid), 타엑스테롤(taraxasterol), 약 1.5%의 정유가 함유되어 있고, 상기와 같은 성분이 해독작용, 항바이러스 작용, 관상동맥 및 관상정맥의 확장작용, 혈류량 증가작용, 혈압강하작용, 항바이러스 및 항균작용, 항병원체작용을 한다.The wild chrysanthemum leaves of Chrysanthemum are choline, stachydrin, adenine, vitamin A, vitamin B 1 , apigenin, apigetrin, 16-β-hydroxy-3-fucedota esterol (16-β-Hydroxy-3-pseudotaraxasterol), Chlorogenic acid, Taxasterol, contains about 1.5% essential oils, and these components are detoxifying, antiviral, and tubular Artery and coronary vein expansion, blood flow increase, blood pressure lowering, antiviral and antibacterial, antipathogenic action.
또한, 소나무과(Pinaceae)의 솔잎은 아스코르빈산(Ascorbic acid : Vitamin C), 카로틴(Carotene), 비타민K, 비타민B, 플라보노이드(Flavonoid), 안토시안(Anthocyan), 탄닌(Tannin), 탄수화물인 유니페르산, P-노나코산을 주성분으로 하는 테레빈유(정유, essential oil)가 0.13%~1.3% 함유되어 있다.In addition, pine needles of Pinaceae are ascorbic acid (Vitamin C), carotene (Carotene), vitamin K, vitamin B, flavonoids (Anthocyan), tannin (Tannin), carbohydrate uniper It contains 0.13% to 1.3% of terevin oil (essential oil), which is composed mainly of acid and P-nonaco acid.
또한, 아랄리아시에(Araliaceae)과에 속하는 가시오가피의 주요성분은 엘레우테로사이드(eleutherosides)로 7개의 주요 엘레우테로사이드(eleutherosides)가 규명되었으며 그 중 엘레우테로사이드(eleutherosides) B와 E가 집중적으로 연구되어지고 있다. 엘레우테로사이드 B는 진정, 불면증, 건망증, 성선 자극, 혈압강하, 자율신경 조정, 당뇨병의 당대사 개선, 당뇨병의 합병증 예방, 간기능 개선 등의 작용을 하고, 엘레우테로사이드 E는 항피로, 항스트레스, 성선자극, 학습향상, 지 구력, 스태미너, 집중력, 항류머티스 등의 작용을 한다. 또한, 가시오가피는 복합다당류를 함유하고 있어 이러한 성분은 면역기능을 향상시키는데 중요한 역할을 한다.In addition, the main component of the thorny stem of the Araliaceae family is eleutherosides, and seven major eleutherosides were identified, among which eleutherosides B and E. Is being studied intensively. Eleutheside B acts as sedation, insomnia, forgetfulness, gonadotropin, lowering blood pressure, autonomic nerve adjustment, improving glucose metabolism, preventing complications of diabetes, and improving liver function. Anti-stress, gonadotropin, learning improvement, endurance, stamina, concentration, antirheumatic, etc. In addition, the barb contains complex polysaccharides, so these components play an important role in improving immune function.
또한, 갈매나무과에 속하는 헛개나무(Hovenia Dulcis)는 열매, 뿌리, 가지, 잎에서 포도당, 사과산, 칼슘을 비롯하여 후랑구라닌, 호베닌, 호배노시드, 하벤산 등의 인체 내의 유익한 성분들이 함유되어 있어 해독작용, 피로회복, 당뇨병의 치료 효과가 있고, “암페롭신과 호베니틴스”은 활성화학 물질로써 간을 보호해 주고 각종 암(간암, 유방암, 위암)에 90%의 암세포 박멸효과가 있다.In addition, Hovenia Dulcis , which belongs to the sea buckthorn family, contains fruit, roots, branches, and leaves with glucose, malic acid and calcium, as well as beneficial components in the human body, such as furangurinine, hobenin, hovanoside, and habenic acid. Detoxification, fatigue recovery, diabetes treatment effect, "amperopsin and hovenitins" is an activating substance to protect the liver and 90% cancer cell eradication effect on various cancers (liver cancer, breast cancer, stomach cancer) .
이하, 본 발명의 구성을 상세히 설명하기로 한다.Hereinafter, the configuration of the present invention will be described in detail.
들국화 잎, 솔잎, 가시오가피 줄기와 잎, 헛개나무 잎을 그늘에서 1차 건조하고 소금물에 살짝 데친 후 그늘에서 건조시키고 다시 햇볕에서 건조하여 도 1에 나타낸 바와 같이 약리성식물 증류액을 제조한다.Wild chrysanthemum leaves, pine needles, thorn stems and leaves, leaves of the barn tree first dried in the shade, slightly boiled in brine, dried in the shade and dried again in the sun to prepare a medicinal plant distillate as shown in FIG.
제 1공정: 원액 제조공정First step: undiluted solution manufacturing process
건조된 들국화의 잎 1㎏, 솔잎 1㎏, 가시오가피의 줄기 및 잎 1㎏, 헛개나무의 잎 1㎏씩 4㎏을 분쇄기로 분쇄하여 가열추출기에 상기 분쇄물과 함께 20ℓ 물을 넣고 들국화 잎, 솔잎, 가시오가피 잎, 헛개나무 잎, 가시오가피 줄기를 40~50℃에서 1~2시간 1차 감압추출하고, 다시 2차로 70~90℃에서 1~2시간 감압추출하여 원액을 제조한다.1 kg of dried wild chrysanthemum leaves, 1 kg of pine needles, 1 kg of stems and leaves of thorns, and 4 kg of leaves of 1 kg of walnut trees were pulverized with a grinder, and 20 liter of water was added to the extract in a heated extract and wild chrysanthemum leaves and pine needles. , Prickly vine leaves, bark leaves, thorny stem stems and extract the primary decompression 1 ~ 2 hours at 40 ~ 50 ℃, and extracted under reduced pressure 1 ~ 2 hours at 70 ~ 90 ℃ again to prepare a stock solution.
제 2공정: 농축액 제조공정Second Process: Concentrate Manufacturing Process
건조된 들국화의 잎 1㎏, 솔잎 1㎏, 가시오가피의 줄기 및 잎 1㎏, 헛개나무 의 잎 1㎏에 에틸알코올 30ℓ를 가하여 70℃에서 3시간 가열하고 다시 2회 반복 실시하여 약리성추출액을 추출하며, 상기 약리성추출액을 70㎝Hg 압력의 감압추출기로 감압농축하고 80~100℃에서 20~40초간 고온 살균하여 농축액을 제조한다.30 l of ethyl alcohol was added to 1 kg of dried wild chrysanthemum leaves, 1 kg of pine needles, 1 kg of thorny stems and leaves, and 1 kg of leaves of hawthorn trees, and heated at 70 ° C. for 3 hours, and then repeated twice to extract pharmacological extracts. The pharmacological extract is concentrated under reduced pressure with a 70 cmHg pressure reduced pressure extractor, and sterilized at 80 to 100 ° C. for 20 to 40 seconds to prepare a concentrate.
제 3공정: 추출액 제조공정Third step: extract manufacturing process
상기 제1공정과 제2공정에 의한 잔류물을 다시 마이크로웨이브로 추출하여 추출액을 제조한다.The residues of the first and second processes are again extracted with microwave to prepare an extract.
제 4공정; 여과 및 증류공정Fourth process; Filtration and Distillation Process
상기 제1공정의 원액과 제2공정의 농축액, 제3공정의 추출액, 원액 의 3배의 물을 혼합하여 왓트만지 1번(Whatman No.1 paper)으로 1차 여과하고, 0.2㎛ 여과막(membrane filter)으로 2차 여과한다. 상기 여과액을 가열하고 증발하는 수증기를 증류관으로 포집하여 0~5℃의 냉각기로 냉각시키고 응축시켜 수득한 약리성응축액을 증류한 후 약리성식물 증류액을 제조한다.The stock solution of the first step, the concentrate of the second step, the extract of the third step, and three times the water of the undiluted solution were mixed firstly with Whatman No. 1 paper, followed by a 0.2 μm membrane. Second filter with filter). Steaming the filtrate is collected by distillation to collect the water vapor in a distillation tube, cooled by a cooler of 0 ~ 5 ℃ and condensation obtained by distilling the pharmacological condensate obtained by distillation of the pharmacological plant.
상기 약리성식물 증류액의 제조배합비의 예는 하기 표 1과 같으며, 표 1에 나타낸 배합비에서 가감 조정될 수 있다.An example of the preparation ratio of the pharmacological plant distillate is shown in Table 1 below, and can be adjusted in the blending ratio shown in Table 1.
상기와 같이 제조된 약리성식물 증류액을 함유한 약수물의 제조공정을 도 2에 따라 상세히 설명하면 다음과 같다.The manufacturing process of the medicinal herb containing the pharmacological plant distillate prepared as described above in detail with reference to FIG.
제 1공정: 혼합공정First step: mixing process
약리성식물 증류액 10.0~20.0중량%, 정제수 80.0~90.0중량%를 정량하고 정제수에 첨가하여 혼합한다.10.0 ~ 20.0% by weight of pharmacological plant distillate, 80.0 ~ 90.0% by weight of purified water are quantified and added to purified water and mixed.
제 2공정:혼합액의 교반공정Second Step: Stirring the Mixture
상기 제 1공정에 의해 혼합된 혼합액을 회전식 교반기로 교반한다.The mixed solution mixed by the first step is stirred with a rotary stirrer.
제 3공정:교반액의 여과공정Third Step: Filtration Step of Stirring Solution
상기 제 2공정에 의해 교반된 교반액을 정제용 여과필터로 여과한다.The stirring liquid stirred by the said 2nd process is filtered by the filtration filter for purification.
제 4공정:포장공정4th step: Packing process
상기 제 3공정에 의해 제조공정이 완료된 약리성식물 증류액을 함유한 음료를 병과 캔과 같은 용기를 세척 및 살균하여 포장한다.The beverage containing the pharmacological plant distillate, which has been manufactured by the third process, is packed by washing and sterilizing containers such as bottles and cans.
상기 제조공정에 의하여 약리성식물 증류액을 함유한 음료의 제조배합비의 예를 하기 표 2에 나타내었다.Table 2 shows an example of the preparation ratio of the beverage containing the pharmacological distillate by the manufacturing process.
상기 표 2에 근거하여 이하에서는 본 발명의 구성을 구체적으로 실시예에 의거하여 보다 상세히 설명하기로 한다. 다만, 본 발명의 권리범위는 실시예에 의하여 본 발명의 청구범위가 한정되는 것은 아니다.Based on the above Table 2, the configuration of the present invention will be described in more detail based on the embodiment. However, the scope of the present invention is not limited to the claims of the present invention by the embodiment.
실시예 1. 약리성증류액을 함유한 약수물을 제조 (1)Example 1. Preparation of medicinal herb containing pharmacological distillate (1)
건조된 들국화의 잎 1㎏, 솔잎 1㎏, 가시오가피의 줄기 및 잎 1㎏, 헛개나무의 잎 1㎏씩 4㎏을 분쇄기로 분쇄하여 가열추출기에 상기 분쇄물과 함께 20ℓ 물을 넣고 들국화 잎, 솔잎, 가시오가피 잎, 헛개나무 잎, 가시오가피 줄기를 45℃에서 2시간 1차 감압추출하고, 다시 2차로 80℃에서 1시간 감압추출하여 원액을 제조하였다. 따로 건조된 들국화의 잎 1㎏, 솔잎 1㎏, 가시오가피의 줄기 및 잎 1㎏, 헛개나무의 잎 1㎏에 에틸알코올 30ℓ를 가하여 70℃에서 3시간 가열하여 약리성 추출액을 추출하며, 상기 약리성추출액을 70㎝Hg 압력의 감압추출기로 감압농축하고 80℃에서 20초간 고온 살균하여 농축액을 제조하였다. 상기 원액과 농축액을 제조하고 남은 잔류물을 다시 마이크로웨이브로 추출하여 추출액을 제조하였다. 상기 원액과 농축액과 추출액과 원액 3배의 물을 혼합하여 왓트만지 1번(Whatman No.1 paper)으로 1차 여과하고, 2차로 0.2㎛ 여과막(membrane filter)으로 여과하였다. 상기 여과액을 가열하고 증발하는 수증기를 증류관으로 포집하여 0~5℃의 냉각기로 냉각시키고 응축시켜 수득한 약리성응축액을 증류한 후 약리성식물 증류액을 제조하였다. 상기 약리성식물 증류액 20.0중량%와 정제수 80.0중량%를 혼합하고 살균하고 교반하고 여과하여 약리성증류액을 함유한 약수물을 제조하였다.1 kg of dried wild chrysanthemum leaves, 1 kg of pine needles, 1 kg of stems and leaves of thorns, and 4 kg of leaves of 1 kg of walnut trees were pulverized with a grinder, and 20 liter of water was added to the extract in a heated extract and wild chrysanthemum leaves and pine needles. , Prunus oak leaves, bark leaves, prickly ivy stems were extracted under reduced pressure at 45 ° C. for 2 hours and again under reduced pressure at 80 ° C. for 1 hour to prepare a stock solution. Separately, 1 kg of dried chrysanthemum leaves, 1 kg of pine needles, 1 kg of stems and leaves of thorns, 1 kg of leaves of huts were added 30 liters of ethyl alcohol and heated at 70 ° C. for 3 hours to extract the pharmacological extracts. The extract was concentrated under reduced pressure with a 70 cmHg pressure reducer and sterilized at 80 ° C. for 20 seconds to prepare a concentrate. The stock solution and the concentrate were prepared, and the remaining residue was extracted again with microwave to prepare an extract. The stock solution, the concentrate, the extract, and three times the water of the stock solution were mixed and filtered first with Whatman No. 1 paper, and secondly with a 0.2 μm membrane filter. The filtrate was heated and evaporated to collect vapor in a distillation tube, cooled by a cooler at 0-5 ° C., and then condensed to obtain the pharmacological condensate obtained by distillation. 20.0% by weight of the pharmacological plant distillate and 80.0% by weight of purified water were mixed, sterilized, stirred and filtered to prepare a herbal solution containing pharmacological distillate.
실시예 2. 약리성증류액을 함유한 약수물을 제조 (2)Example 2. Preparation of medicinal herb containing pharmacological distillate (2)
건조된 들국화의 잎 1㎏, 솔잎 1㎏, 가시오가피의 줄기 및 잎 1㎏, 헛개나무의 잎 1㎏씩 4㎏을 분쇄기로 분쇄하여 가열추출기에 상기 분쇄물과 함께 20ℓ물을 넣고 들국화 잎, 솔잎, 가시오가피 잎, 헛개나무 잎, 가시오가피 줄기를 45℃에서 12시간 1차 감압추출하고, 다시 2차로 80℃에서 1시간 감압추출하여 원액을 제조하였다. 따로 건조된 들국화의 잎 1㎏, 솔잎 1㎏, 가시오가피의 줄기 및 잎 1㎏, 헛개나무의 잎 1㎏에 에틸알코올 30ℓ를 가하여 70℃에서 3시간 가열하여 약리성추 출액을 추출하며, 상기 약리성추출액을 70㎝Hg 압력의 감압추출기로 감압농축하고 90℃에서 30초간 고온 살균하여 농축액을 제조하였다. 상기 원액과 농축액을 제조하고 남은 잔류물을 다시 마이크로웨이브로 추출하여 추출액을 제조하였다. 상기 원액과 농축액과 추출액과 원액 3배의 물을 혼합하여 왓트만지 1번으로 1차 여과하고, 2차로 0.2㎛ 여과막(membrane filter)으로 여과하였다. 상기 여과액을 가열하고 증발하는 수증기를 증류관으로 포집하여 2.5℃의 냉각기로 냉각시키고 응축시켜 수득한 약리성응축액을 증류한 후 약리성식물 증류액을 제조하였다. 상기 약리성식물 증류액 15.0중량%와 정제수 85.0중량%를 혼합하고 살균하고 교반하고 여과하여 약리성증류액을 함유한 약수물을 제조하였다.1 kg of dried wild chrysanthemum leaves, 1 kg of pine needles, 1 kg of stems and leaves of thorns, 1 kg of leaves of huts, 4 kg each were pulverized with a grinder, and 20 liters of water was added to the extract in a heated extract and wild chrysanthemum leaves and pine needles. , Prunus oak leaves, shed leaves and thorn stems were extracted at 45 ° C for 1 hour under reduced pressure, and again extracted under reduced pressure at 80 ° C for 1 hour to prepare a stock solution. Separately, 1 kg of dried chrysanthemum leaves, 1 kg of pine needles, 1 kg of stems and leaves of thorny oak, and 1 kg of leaves of huts were added 30 l of ethyl alcohol, and heated at 70 ° C. for 3 hours to extract the pharmacological extracts. The extract was concentrated under reduced pressure with a 70 cmHg pressure reducer and sterilized at 90 ° C. for 30 seconds to prepare a concentrate. The stock solution and the concentrate were prepared, and the remaining residue was extracted again with microwave to prepare an extract. The stock solution, the concentrate, the extract, and three times the water of the stock solution were mixed and filtered first with Whatman No. 1, and secondly with a 0.2 μm membrane filter. The filtrate was heated and evaporated with steam to collect in a distillation tube, cooled with a condenser of 2.5 ℃ and condensation obtained by distilling the pharmacological condensate obtained by distillation to prepare a pharmacological plant distillate. 15.0% by weight of the pharmacological plant distillate and 85.0% by weight of purified water were mixed, sterilized, stirred and filtered to prepare a herbal solution containing pharmacological distillate.
실시예 3. 약리성증류액을 함유한 약수물을 제조 (3)Example 3. Preparation of medicinal herb containing pharmacological distillate (3)
건조된 들국화의 잎 1㎏, 솔잎 1㎏, 가시오가피의 줄기 및 잎 1㎏, 헛개나무의 잎 1㎏씩 4㎏을 분쇄기로 분쇄하여 가열추출기에 상기 분쇄물과 함께 20ℓ 물을 넣고 들국화 잎, 솔잎, 가시오가피 잎, 헛개나무 잎, 가시오가피 줄기를 45℃에서 12시간 1차 감압추출하고, 다시 2차로 80℃에서 1시간 감압추출하여 원액을 제조하였다. 따로 건조된 들국화의 잎 1㎏, 솔잎 1㎏, 가시오가피의 줄기 및 잎 1㎏, 헛개나무의 잎 1㎏에 에틸알코올 30ℓ를 가하여 70℃에서 3시간 가열하여 약리성추출액을 추출하며, 상기 약리성추출액을 70㎝Hg 압력의 감압추출기로 감압농축하고 100℃에서 40초간 고온 살균하여 농축액을 제조하였다. 상기 원액과 농축액을 제조하고 남은 잔류물을 다시 마이크로웨이브로 추출하여 추출액을 제조하였다. 상기 원액과 농축액과 추출액과 원액 3배의 물을 혼합하여 왓트만지 1번으로 1차 여과하 고, 2차로 0.2㎛ 여과막(membrane filter)으로 여과하였다. 상기 여과액을 가열하고 증발하는 수증기를 증류관으로 포집하여 5℃의 냉각기로 냉각시키고 응축시켜 수득한 약리성응축액을 증류한 후 약리성식물 증류액을 제조하였다. 상기 약리성식물 증류액 10.0 중량%와 정제수 90.0 중량%를 혼합하고 살균하고 교반하고 여과하여 약리성증류액을 함유한 약수물을 제조하였다.1 kg of dried wild chrysanthemum leaves, 1 kg of pine needles, 1 kg of stems and leaves of thorns, and 4 kg of leaves of 1 kg of walnut trees were pulverized with a grinder, and 20 liter of water was added to the extract in a heated extract and wild chrysanthemum leaves and pine needles. , Prunus oak leaves, shed leaves and thorn stems were extracted at 45 ° C for 1 hour under reduced pressure, and again extracted under reduced pressure at 80 ° C for 1 hour to prepare a stock solution. Separately, 1 kg of dried chrysanthemum leaves, 1 kg of pine needles, 1 kg of stems and leaves of thorny oak, and 1 kg of leaves of huts were added 30 liters of ethyl alcohol and heated at 70 ° C. for 3 hours to extract the pharmacological extracts. The extract was concentrated under reduced pressure with a 70 cmHg pressure reducer and sterilized at 100 ° C. for 40 seconds to prepare a concentrate. The stock solution and the concentrate were prepared, and the remaining residue was extracted again with microwave to prepare an extract. The stock solution, the concentrate, the extract, and three times the water of the stock solution were mixed and filtered first with Whatman No. 1, and secondly with a 0.2 μm membrane filter. The filtrate was heated and evaporated to collect steam in a distillation tube, cooled by condensation at 5 ° C., and condensed to obtain the pharmacological condensate obtained by distillation. 10.0% by weight of the pharmacological plant distillate and 90.0% by weight of purified water were mixed, sterilized, stirred and filtered to prepare a herbal solution containing pharmacological distillate.
또한 본 발명은 상기 들국화, 헛개나무, 가시오가피 및 솔잎 이외에 감초, 속단, 구기자, 두충, 산액, 복분자 딸기, 오가피, 오미자, 제비꽃, 지치, 향유, 엉겅퀴, 천마, 꿀풀, 민들레, 해송, 겨우살이, 하수오, 황기, 계피, 황금, 금전초, 도라지, 더덕, 칡, 쑥, 건강, 당귀, 모과, 측백나무, 차전차, 회향, 삼백초, 우슬 , 숙지황, 단삼, 독활, 홍화, 홍화씨, 소두구, 사군자 또는 행인를 첨가하여 상기 실시예 1, 2 또는 3에서 제조한 방법으로 약리성 증류액을 함유한 약수물을 제조할 수 있다.In addition, the present invention is in addition to the wild chrysanthemum, bark, thorns, pine needles and pine needles, licorice, gojija, tofu, mountain liquids, bokbunja strawberry, squid, schisandra, violet, branch, scented oil, thistle, cheonma, nectar, dandelion, larch, mistletoe, sewage , Astragalus, Cinnamon, Golden, Gemini, Bellflower, Deodeok, Mugwort, Mugwort, Health, Angelica, Chinese quince, Cypress, Chariot, Fennel, Triticales, Emulsion, Sukjihwang, Dansam, Poisonous, Safflower, Safflower seed, Small head A medicinal herb containing pharmacological distillate can be prepared by the method prepared in Examples 1, 2 or 3 by adding a passerby.
상기 실시예 1에서 제조한 약리성식물 증류액이 항균성을 가지는지 확인하기 위하여 대장균 및 녹농균에 대한 항균력, 음이온 발생율을 시험하였다.In order to determine whether the pharmacological plant distillate prepared in Example 1 has antimicrobial activity, the antibacterial activity against E. coli and Pseudomonas aeruginosa and anion generation rate were tested.
시험예 1. 약리성식물 증류액의 항균성 검토Test Example 1. Examination of antimicrobial activity of pharmacological plant distillate
공시균으로서 대장균(Escherichia coil ATCC No.25922), 녹농균 (Pseudomonas aeruginosa ATCC No.15442)을 사용하고 배지는 육즙배지, 한천배지, 트립톤 글로코오스(Tryptone Glucose Extract)한천배지를 사용하였다.Escherichia coli (Escherichia coil ATCC No.25922) and Pseudomonas aeruginosa ATCC No. 15442 were used as test bacteria, and broth, agar medium, and Tryptone Glucose Extract agar medium were used as a medium.
공시균을 배양하기 위하여 4㎜ 루프를 사용하여 소장 중인 균주로부터 10㎖의 육즙배지(5.1)에 이식하고 37℃에서 24시간 배양하였다. 저장 중인 균주는 한천 배지의 사면 배양기에 보존하였고 저장 균주는 5℃에 저장하고 한달에 한번씩 계대 배양시켰다.In order to incubate the specimens, a 4 mm loop was used to transplant 10 ml of broth (5.1) from the small intestine and incubated at 37 ° C. for 24 hours. Strains in storage were stored in a slope incubator of agar medium and stored strains were stored at 5 ° C. and passaged once a month.
접종시간 “0”에서의 시험구(약리성식물 증류액 처리함) 또는 대조구(약리성식물 증류액 처리하지 않음)으로 부터 재생된 세균의 수가 4~6×105이 되도록 24시간 배양한 육즙 배양 균액을 알맞게 희석하여 이 액 5㎖를 접종원으로 사용하였다. 이때 배양 균액의 희석은 생리 식염수를 사용하였다.Juicy juice cultured for 24 hours so that the number of bacteria regenerated from the test group (treated with pharmacological plant distillate) or the control group (without pharmacological plant distillate) at the inoculation time “0” is 4-6 × 10 5. The culture microbial solution was diluted appropriately and 5 ml of this solution was used as the inoculum. At this time, the dilution of the culture bacteria was used saline solution.
시험구에는 5㎖ 약리성식물 증류액을 첨가하였다. 대장균을 사용할 때는 24시간 동안 배양된 세균을 진탕하고, 접종원을 준비하기 전에 15분 동안 세워두었다. 피펫을 사용하여 접종원 5㎖(각 용기에 대하여)를 시험구 및 대조구 위에 골고루 분포되도록 주의해서 떨어뜨렸다.5 mL pharmacological plant distillate was added to the test zone. When using E. coli, bacteria cultured for 24 hours were shaken and left standing for 15 minutes before preparing the inoculum. Using a pipette, 5 ml of inoculum (for each container) was carefully dropped to distribute evenly on the test and control.
약리성식물 증류액은 세균수 혹은 감소율로서 표시하고, 유효숫자 2자리로 표시하였다.The pharmacological plant distillate was expressed as the number of bacteria or the reduction rate, and was expressed by two significant figures.
시험예 1에 의한 결과를 하기 표 3 및 도 3, 4에 나타낸다.The results according to Test Example 1 are shown in Table 3 below and FIGS. 3 and 4.
도 3, 4에 나타낸 바와 같이 본 발명인 약리성식물 증류액을 처리한 시험구의 경우 대장균, 녹농균의 증식이 전혀 나타나지 않았으나 대조구의 경우 대장균 및 녹농균의 콜로니가 현저하게 증가하였다.As shown in Figures 3 and 4, the experimental group treated with the pharmacological plant distillate of the present invention showed no growth of E. coli and Pseudomonas aeruginosa, but the control group significantly increased colonies of E. coli and Pseudomonas aeruginosa.
따라서 본 발명의 원료가 되는 들국화, 소나무, 가시오가피, 헛개나무가 항균성을 지님을 입증하였다.Therefore, wild chrysanthemum, pine, thorny oak bark, and barn tree, which are raw materials of the present invention, proved to have antibacterial properties.
시험예 2. 약리성식물 증류액의 방사율 측정Test Example 2 Measurement of Emissivity of Distillate of Pharmacological Plants
본 시험예는 방사율을 측정하는 것으로 흑체로를 대비측으로 하여 40℃에 설정하고 해바실 방수몰탈을 같은 온도로 하여 520㎛ 파장범위를 적외분광계를 이용하여 방사율을 측정하였다. 약리성식물 증류액을 시료로 취하여 37℃에서 퓨리에 변환 적외선 분광계(FT-IR-Spectrometer 기종; FT/IR-4000/6000Series, 제조원; ㈜성진아이앤드티)를 이용하여 흑체(BLACK BODY)를 대비하여 하기 표 4에 그 결과를 나타내었다.In this test example, the emissivity was measured at 40 ° C with the black body furnace as the contrast side, and the emissivity was measured using an infrared spectrometer with a wavelength range of 520 µm with haebsil waterproof mortar at the same temperature. Pharmacological plant distillate was taken as a sample to prepare a black body using a Fourier transform infrared spectrometer (FT-IR-Spectrometer model; FT / IR-4000 / 6000Series, manufacturer; Sungjin I & T Co., Ltd.) The results are shown in Table 4 below.
원적외선의 방사율은 0.89~0.90 이상이어야 원적외선을 방사하는데, 본 발명은 0.902의 방사율을 나타내었다. 흑체(BLACK BODY)는 모든 복사(빛)를 완전히 흡수하는 가상의 물체인 원적외선이 100%인 가상의 물질을 기준으로 본 발명인 약리성식물 증류액의 원적외선 방사율이 90.2%로 측정되어 0.902로 환산하여 나타내었다. Far-infrared emissivity should be more than 0.89 ~ 0.90 to emit far infrared rays, the present invention showed an emissivity of 0.902. Black body (BLACK BODY) is based on the imaginary material 100% of far infrared rays, a virtual object that completely absorbs all radiation (light), the far-infrared emissivity of the distillate of pharmacological plants of the present invention is measured as 90.2% and converted to 0.902 Indicated.
시험예 3. 약리성식물 증류액의 음이온 발생 측정Test Example 3 Measurement of Anion Generation in Pharmacological Plant Distillates
입자전하측정기(기종; PCD, 제조원; ㈜삼보과학)를 이용하여 실내온도 25℃, 습도 43%, 대기중 음이온수 108/㏄조건에서 시험하였으며 본 발명인 약리성식물 증류액 100㎖에서 방출되는 음이온을 측정하여 단위체적당 ION수로 표시하였다.Anion released from 100 ml of pharmacological plant distillate of the present invention was tested at room temperature 25 ℃, humidity 43%, anion water 108 / 보 condition using a particle charge measuring instrument (model; PCD, Manufacture; Sambo Science) Was measured and expressed as the number of IONs per unit volume.
상기 시험예 2에 의한 결과를 표 5에 나타낸 바와 같이 본 발명은 약리성식물 증류액 100㎖당 188의 음이온을 발생시켰다. 음이온은 마이너스(-)전기를 띠는 이온으로 미국 캘리포니아 버클리대학의 크루거(Kruger)박사와 예루살렘의 헤브류(Hebrew)대학의 설만(Sulman)박사의 보고에 따르면 음이온이 공기 1㏄당 1,000개 이상으로 풍부해지면 뇌에서 알파(α)의 활동을 증가시켜 천식과 편두통의 원인인 걱정과 긴장을 완화시켜 준다는 것이다. 또한 천식과 같은 호흡기 질환을 일으키는 신경호르몬인 세로토닌(Serotonine)과 자유 히스타민(Free Histamine)을 억제하는 효과가 있다고 한다.As shown in Table 5, the result of Test Example 2 generated 188 anions per 100 ml of pharmacological plant distillate. Negative ions are negatively charged ions, and Dr. Kruger of the University of California, Berkeley, and Dr. Sulman of the University of Hebrew, Jerusalem, reported that more than 1,000 anions per air. Enriched by the brain increases the activity of alpha (α) to relieve the worry and tension that causes asthma and migraines. It also has the effect of inhibiting serotonin and free histamine, which are neurohormones that cause respiratory diseases such as asthma.
상기와 같은 연구 결과에 비추어 볼 때 본 발명인 약리성식물 증류액 또한 세로토닌(Serotonine)과 자유 히스타민(Free Histamine)을 억제하는 효과가 있을 것으로 유추할 수 있었다.In light of the above research results, the pharmacological distillate of the present invention could also be inferred to have an effect of inhibiting serotonin and free histamine.
시험예 4. 약리성식물 증류액을 함유한 음료의 관능검사Test Example 4 Sensory Evaluation of Beverages Containing Pharmacological Plant Distillates
상기 실시예 1, 2, 3에서 제조한 약리성식물 증류액을 함유한 음료를 음용하고 기호성의 정도를 관능검사하였다. 관능검사는 총 80명의 인원을 대상으로 5점 평가법으로 실시하였으며, 상기 관능검사의 결과를 하기 표 6에 나타내었다.Drinks containing the pharmacological plant distillates prepared in Examples 1, 2, and 3 were drinked and the degree of palatability was tested. The sensory test was carried out by a five-point evaluation method for a total of 80 people, the results of the sensory test are shown in Table 6 below.
상기 표 6에 의한 관능검사의 결과는 색, 맛, 향, 전체적 기호도 면에서 전체적으로 양호하였으며, 특히 색의 항목에서 양호한 결과를 얻은 것은 약리성식물 증류액을 첨가하여도 음료의 색에 영향을 미치지 않았기 때문이다.The results of the sensory test according to Table 6 were generally good in terms of color, taste, aroma, and overall acceptability. Particularly, a good result in terms of color did not affect the color of the beverage even if pharmacological distillate was added. Because it did not.
상기와 같은 관능검사의 결과로 본 발명을 단독으로 섭취할 수 있고, 음료에 첨가하여 음용하여도 기호도가 높은 것으로 나타났다. As a result of the sensory test as described above, the present invention can be ingested alone, and even when added to a drink, the preference is high.
본 발명은 상술한 특정의 실시예, 시험예, 도표 또는 도면에 기재된 내용에 기술적 사상이 한정되지 아니하며, 청구범위에서 청구하는 본 발명의 요지를 벗어남이 없이 당해 발명이 속하는 기술분야에서 통상의 지식을 가진 자라면 누구든지 다양한 변형의 실시가 가능한 것은 물론이고, 그와 같은 변경은 청구범위 기재의 범위 내에 있게 된다.The present invention is not limited to the technical spirit of the contents described in the specific embodiments, test examples, diagrams or drawings described above, and the general knowledge in the technical field to which the present invention pertains without departing from the gist of the present invention as claimed in the claims. Of course, any person having a variety of modifications can be made, and such changes are within the scope of the claims.
이상 설명한 바와 같이 본 발명은 들국화잎, 솔잎, 가시오가피, 헛개나무잎을 포함한 약리성식물 증류액을 함유한 약수물의 제조방법 및 상기 방법으로 제조된 약수물에 관한 것으로, 본 발명은 약리성식물 증류액이 대장균과 녹농균에 대해 저항력을 가지는 효과가 있다.As described above, the present invention relates to a method of preparing a medicinal herb containing medicinal plant distillates, including wild chrysanthemum leaves, pine needles, thorn leaves, and bark leaves, and the medicinal herb prepared by the above method. It is effective in resisting E. coli and Pseudomonas aeruginosa.
또한 본 발명은 원적외선을 방사하여 스트레스가 없어지고 위장상태가 향상 되는 효과가 있다.In addition, the present invention has the effect of eliminating the stress by radiation far infrared rays to improve the gastrointestinal state.
또한 본 발명은 음이온 발생 시험을 한 결과 음이온 발생이 현저하여 알파(α)파의 활동을 증가시켜 천식과 편두통을 완화시켜 주고 천식과 같은 호흡기 질환을 일으키는 신경호르몬인 세로토닌(Serotonine)과 자유 히스타민(Free Histamine)을 억제하는 효과가 있다.In addition, the present invention is an anion generation test results in a significant anion generation to increase the activity of alpha (α) waves to relieve asthma and migraine headaches, serotonin (Serotonine) and free histamine (neurohormones causing respiratory diseases such as asthma) Free Histamine) is effective.
Claims (2)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020040104316A KR100663969B1 (en) | 2004-12-10 | 2004-12-10 | The production method for distillate including Chrysanthemum, Pinanceae, Acanthopanax and Rhamnaceae and the distillate thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020040104316A KR100663969B1 (en) | 2004-12-10 | 2004-12-10 | The production method for distillate including Chrysanthemum, Pinanceae, Acanthopanax and Rhamnaceae and the distillate thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
KR20060065855A KR20060065855A (en) | 2006-06-14 |
KR100663969B1 true KR100663969B1 (en) | 2007-01-02 |
Family
ID=37160874
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1020040104316A KR100663969B1 (en) | 2004-12-10 | 2004-12-10 | The production method for distillate including Chrysanthemum, Pinanceae, Acanthopanax and Rhamnaceae and the distillate thereof |
Country Status (1)
Country | Link |
---|---|
KR (1) | KR100663969B1 (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100715378B1 (en) | 2006-08-03 | 2007-05-07 | 전기곤 | Anion generating composition using vegetable material as main ingredient |
KR100715396B1 (en) | 2006-08-03 | 2007-05-07 | 전기곤 | Method of preparing anion generating composition using vegetable material as main ingredient |
KR101204761B1 (en) | 2010-10-28 | 2012-11-26 | (주)국심 | A tea of chrysanthemum and A Manufacturing Method therefor |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100842839B1 (en) * | 2006-10-31 | 2008-07-02 | 한국식품연구원 | Anti-hypertensive Beverage Composition Comprising Acanthopanax senticosus and Process for Preparing the Same |
KR100896947B1 (en) * | 2008-03-07 | 2009-05-14 | 최용길 | Method for manufacturing acanthopanax tea, and acanthopanax tea made by the same |
KR101217426B1 (en) * | 2011-10-10 | 2013-01-02 | 이용현 | A drink using extract of herb mixture and a manufacturing method therefor |
KR102262335B1 (en) * | 2019-11-18 | 2021-06-08 | 신형자 | Preparing method of Kimchi with oriental herb and Kimchi prepared by the same |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR0178862B1 (en) * | 1996-04-13 | 1999-02-01 | 이백천 | Health beverage and its preparation |
-
2004
- 2004-12-10 KR KR1020040104316A patent/KR100663969B1/en not_active IP Right Cessation
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR0178862B1 (en) * | 1996-04-13 | 1999-02-01 | 이백천 | Health beverage and its preparation |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100715378B1 (en) | 2006-08-03 | 2007-05-07 | 전기곤 | Anion generating composition using vegetable material as main ingredient |
KR100715396B1 (en) | 2006-08-03 | 2007-05-07 | 전기곤 | Method of preparing anion generating composition using vegetable material as main ingredient |
KR101204761B1 (en) | 2010-10-28 | 2012-11-26 | (주)국심 | A tea of chrysanthemum and A Manufacturing Method therefor |
Also Published As
Publication number | Publication date |
---|---|
KR20060065855A (en) | 2006-06-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
KR101501326B1 (en) | Manufacturing method of the composition using 125 kinds of medicinal herb extracts | |
KR101541516B1 (en) | Mathod Manufacturing lON Mineral Using Silk worm, Muberry leaf, and Muberry twig And Health Drink Manufactured by this | |
KR100884707B1 (en) | Method for Production of Beverage Fermented by Lactic Acid Bacteria using the Fluid of a Tree and Beverage Fermented by Lactic Acid Bacteria thereof | |
KR102133447B1 (en) | Drink for improving sleep disturbance and sleep inducing, and Manufacturing Method of the Same | |
KR100663969B1 (en) | The production method for distillate including Chrysanthemum, Pinanceae, Acanthopanax and Rhamnaceae and the distillate thereof | |
KR102289438B1 (en) | health food composition manufacturing method including Hovenia dulcis, Sorbus commixta, Alnus Japonica and kudzu vine, health food composition manufactured by the same | |
CN105076728B (en) | Se-enriched herbal medicine feed addictive and preparation method thereof | |
CN106047595A (en) | Fragrant rose wine and preparation method thereof | |
CN103919139B (en) | Female beautifying granule and preparation method thereof | |
KR101333152B1 (en) | Honey containing lavender | |
CN105146653A (en) | Moringa oleifera beverage and preparation method thereof | |
KR101404309B1 (en) | The method of preparing clear and cool drink using the traditional oriental medicine of plant including polypara codata bueck | |
KR102452902B1 (en) | Herbal medicinal liquor and its manufacturing method | |
KR101159523B1 (en) | The jam manufacturing method using mushroom | |
KR100568090B1 (en) | A drink composition of the fermented Houttuynia cordata thunb | |
KR101950983B1 (en) | Composition of elderberry and mehod of making beverage using the same | |
KR100512449B1 (en) | The method for manufacturing of tea | |
KR20200089947A (en) | A Method of Making Kochujang Using Antibacterial Plant Complex Fermented Liquid | |
CN105495179A (en) | Peony beverage | |
KR20200131555A (en) | Composition for health functional beverage and manufacturing method thereof | |
KR20160123552A (en) | Health drink and manufacturing method thereby | |
KR101891171B1 (en) | Manufacture Method and Apparatus for Fructus Mume | |
CN104663858A (en) | Method for extracting biological fresh-keeping agent from honeysuckle, and applications of biological fresh-keeping agent in grape fresh keeping | |
CN109362926A (en) | One kind is clear liver and improved vision haw thorn and chrysanthemum tea and its processing method | |
CN109007080A (en) | A kind of processing method of Small-leaf Kuding tea |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A201 | Request for examination | ||
E902 | Notification of reason for refusal | ||
E701 | Decision to grant or registration of patent right | ||
GRNT | Written decision to grant | ||
FPAY | Annual fee payment |
Payment date: 20091215 Year of fee payment: 4 |
|
LAPS | Lapse due to unpaid annual fee |