KR100628586B1 - 3-데속시-비타민 디3 유사 에스테르 - Google Patents

3-데속시-비타민 디3 유사 에스테르 Download PDF

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Publication number
KR100628586B1
KR100628586B1 KR1020047004110A KR20047004110A KR100628586B1 KR 100628586 B1 KR100628586 B1 KR 100628586B1 KR 1020047004110 A KR1020047004110 A KR 1020047004110A KR 20047004110 A KR20047004110 A KR 20047004110A KR 100628586 B1 KR100628586 B1 KR 100628586B1
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KR
South Korea
Prior art keywords
formula
group
compound
alkyl
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
KR1020047004110A
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English (en)
Korean (ko)
Other versions
KR20040035853A (ko
Inventor
우스코코빅밀란라도제
Original Assignee
에프. 호프만-라 로슈 아게
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Publication of KR20040035853A publication Critical patent/KR20040035853A/ko
Application granted granted Critical
Publication of KR100628586B1 publication Critical patent/KR100628586B1/ko
Anticipated expiration legal-status Critical
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
KR1020047004110A 2001-09-21 2002-09-12 3-데속시-비타민 디3 유사 에스테르 Expired - Fee Related KR100628586B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US32395701P 2001-09-21 2001-09-21
US32387001P 2001-09-21 2001-09-21
US60/323,870 2001-09-21
US60/323,957 2001-09-21
PCT/EP2002/010233 WO2003027065A1 (en) 2001-09-21 2002-09-12 3-desoxy-vitamin d3 analog esters

Publications (2)

Publication Number Publication Date
KR20040035853A KR20040035853A (ko) 2004-04-29
KR100628586B1 true KR100628586B1 (ko) 2006-09-26

Family

ID=26984180

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020047004110A Expired - Fee Related KR100628586B1 (ko) 2001-09-21 2002-09-12 3-데속시-비타민 디3 유사 에스테르

Country Status (14)

Country Link
EP (1) EP1430026A1 (https=)
JP (1) JP2005503434A (https=)
KR (1) KR100628586B1 (https=)
CN (1) CN1285573C (https=)
AU (1) AU2002338672B2 (https=)
BR (1) BR0212719A (https=)
CA (1) CA2459789A1 (https=)
MX (1) MXPA04002640A (https=)
PA (1) PA8554901A1 (https=)
PE (1) PE20030429A1 (https=)
PL (1) PL370352A1 (https=)
RU (1) RU2296121C2 (https=)
UY (1) UY27448A1 (https=)
WO (1) WO2003027065A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL376148A1 (en) * 2002-10-23 2005-12-27 Leo Pharma A/S Vitamin d analogues, compositions comprising said analogues and their use
WO2006036813A2 (en) * 2004-09-24 2006-04-06 Bioxell S.P.A. 20-cycloalkyl,26,27-alkyl/haloalkyl vitamin d3 compounds and methods of use thereof
CA2586679A1 (en) 2004-11-12 2006-05-18 Bioxell Spa Combined use of vitamin d derivatives and anti-proliferative agents for treating bladder cancer
CN102124301B (zh) 2008-08-22 2014-04-02 Nxp股份有限公司 基于位置的服务
CN110339205B (zh) * 2019-08-19 2021-08-24 山东德信生物科技有限公司 富氢水组合物在抑制六价铬诱导的df-1细胞内质网应激及自噬中的应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG70010A1 (en) * 1996-05-23 2000-01-25 Hoffmann La Roche Fluorinated vitamin d3 analogs
WO1999012894A1 (en) * 1997-09-08 1999-03-18 F. Hoffmann-La Roche Ag 1,3-dihydroxy-20,20-dialkyl-vitamin d3 analogs
US6331642B1 (en) * 1999-07-12 2001-12-18 Hoffmann-La Roche Inc. Vitamin D3 analogs

Also Published As

Publication number Publication date
KR20040035853A (ko) 2004-04-29
JP2005503434A (ja) 2005-02-03
PA8554901A1 (es) 2003-12-10
CA2459789A1 (en) 2003-04-03
EP1430026A1 (en) 2004-06-23
RU2004112217A (ru) 2005-07-10
UY27448A1 (es) 2003-03-31
PL370352A1 (en) 2005-05-16
CN1556795A (zh) 2004-12-22
AU2002338672B2 (en) 2006-03-09
PE20030429A1 (es) 2003-05-15
BR0212719A (pt) 2004-08-03
RU2296121C2 (ru) 2007-03-27
CN1285573C (zh) 2006-11-22
MXPA04002640A (es) 2004-06-07
WO2003027065A1 (en) 2003-04-03

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