KR100591539B1 - Dietary supplement composition - Google Patents
Dietary supplement composition Download PDFInfo
- Publication number
- KR100591539B1 KR100591539B1 KR1020030073170A KR20030073170A KR100591539B1 KR 100591539 B1 KR100591539 B1 KR 100591539B1 KR 1020030073170 A KR1020030073170 A KR 1020030073170A KR 20030073170 A KR20030073170 A KR 20030073170A KR 100591539 B1 KR100591539 B1 KR 100591539B1
- Authority
- KR
- South Korea
- Prior art keywords
- composition
- effect
- powder
- vitamin
- seeds
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 41
- 235000015872 dietary supplement Nutrition 0.000 title claims abstract description 20
- 239000000843 powder Substances 0.000 claims abstract description 30
- 235000021329 brown rice Nutrition 0.000 claims abstract description 17
- 235000013339 cereals Nutrition 0.000 claims abstract description 16
- 241000411851 herbal medicine Species 0.000 claims abstract description 16
- 235000003261 Artemisia vulgaris Nutrition 0.000 claims abstract description 9
- 240000006891 Artemisia vulgaris Species 0.000 claims abstract description 9
- 235000002595 Solanum tuberosum Nutrition 0.000 claims abstract description 8
- 244000061456 Solanum tuberosum Species 0.000 claims abstract description 8
- 235000002732 Allium cepa var. cepa Nutrition 0.000 claims abstract description 7
- 239000004480 active ingredient Substances 0.000 claims abstract description 6
- 235000015277 pork Nutrition 0.000 claims abstract description 6
- 240000002045 Guettarda speciosa Species 0.000 claims abstract description 5
- 235000001287 Guettarda speciosa Nutrition 0.000 claims abstract description 5
- 244000046052 Phaseolus vulgaris Species 0.000 claims abstract description 5
- 235000010627 Phaseolus vulgaris Nutrition 0.000 claims abstract description 5
- 235000013527 bean curd Nutrition 0.000 claims abstract description 3
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims description 14
- 241001474374 Blennius Species 0.000 claims description 12
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 12
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims description 7
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 claims description 7
- 241000700159 Rattus Species 0.000 claims description 7
- 229940088594 vitamin Drugs 0.000 claims description 7
- 229930003231 vitamin Natural products 0.000 claims description 7
- 235000013343 vitamin Nutrition 0.000 claims description 7
- 239000011782 vitamin Substances 0.000 claims description 7
- 229930091371 Fructose Natural products 0.000 claims description 6
- 239000005715 Fructose Substances 0.000 claims description 6
- 230000002378 acidificating effect Effects 0.000 claims description 6
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 claims description 5
- 241000234282 Allium Species 0.000 claims description 5
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 claims description 5
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 claims description 5
- 229930003268 Vitamin C Natural products 0.000 claims description 5
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 claims description 5
- -1 hoedo Substances 0.000 claims description 5
- 235000019155 vitamin A Nutrition 0.000 claims description 5
- 239000011719 vitamin A Substances 0.000 claims description 5
- 235000019154 vitamin C Nutrition 0.000 claims description 5
- 239000011718 vitamin C Substances 0.000 claims description 5
- 229940045997 vitamin a Drugs 0.000 claims description 5
- 235000021307 Triticum Nutrition 0.000 claims description 4
- 241000512259 Ascophyllum nodosum Species 0.000 claims description 3
- 235000000832 Ayote Nutrition 0.000 claims description 3
- 241000132536 Cirsium Species 0.000 claims description 3
- 240000004244 Cucurbita moschata Species 0.000 claims description 3
- 235000009854 Cucurbita moschata Nutrition 0.000 claims description 3
- 235000009804 Cucurbita pepo subsp pepo Nutrition 0.000 claims description 3
- 229930003451 Vitamin B1 Natural products 0.000 claims description 3
- 229930003427 Vitamin E Natural products 0.000 claims description 3
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims description 3
- 210000001161 mammalian embryo Anatomy 0.000 claims description 3
- 239000006187 pill Substances 0.000 claims description 3
- 235000015136 pumpkin Nutrition 0.000 claims description 3
- 229960003495 thiamine Drugs 0.000 claims description 3
- DPJRMOMPQZCRJU-UHFFFAOYSA-M thiamine hydrochloride Chemical compound Cl.[Cl-].CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N DPJRMOMPQZCRJU-UHFFFAOYSA-M 0.000 claims description 3
- 235000010374 vitamin B1 Nutrition 0.000 claims description 3
- 239000011691 vitamin B1 Substances 0.000 claims description 3
- 235000019165 vitamin E Nutrition 0.000 claims description 3
- 239000011709 vitamin E Substances 0.000 claims description 3
- 229940046009 vitamin E Drugs 0.000 claims description 3
- 150000003722 vitamin derivatives Chemical class 0.000 claims description 3
- LUEWUZLMQUOBSB-FSKGGBMCSA-N (2s,3s,4s,5s,6r)-2-[(2r,3s,4r,5r,6s)-6-[(2r,3s,4r,5s,6s)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(2r,4r,5s,6r)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol Chemical compound O[C@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@@H](O[C@@H]2[C@H](O[C@@H](OC3[C@H](O[C@@H](O)[C@@H](O)[C@H]3O)CO)[C@@H](O)[C@H]2O)CO)[C@H](O)[C@H]1O LUEWUZLMQUOBSB-FSKGGBMCSA-N 0.000 claims description 2
- 240000006108 Allium ampeloprasum Species 0.000 claims description 2
- 235000005254 Allium ampeloprasum Nutrition 0.000 claims description 2
- 229920002581 Glucomannan Polymers 0.000 claims description 2
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims description 2
- 229930003316 Vitamin D Natural products 0.000 claims description 2
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 claims description 2
- 229940041514 candida albicans extract Drugs 0.000 claims description 2
- 235000020776 essential amino acid Nutrition 0.000 claims description 2
- 239000003797 essential amino acid Substances 0.000 claims description 2
- 229940029982 garlic powder Drugs 0.000 claims description 2
- 229940046240 glucomannan Drugs 0.000 claims description 2
- 235000013372 meat Nutrition 0.000 claims description 2
- 229920001542 oligosaccharide Polymers 0.000 claims description 2
- 150000002482 oligosaccharides Chemical class 0.000 claims description 2
- 235000012015 potatoes Nutrition 0.000 claims description 2
- 235000020183 skimmed milk Nutrition 0.000 claims description 2
- 235000021122 unsaturated fatty acids Nutrition 0.000 claims description 2
- 150000004670 unsaturated fatty acids Chemical class 0.000 claims description 2
- 235000019166 vitamin D Nutrition 0.000 claims description 2
- 239000011710 vitamin D Substances 0.000 claims description 2
- 150000003710 vitamin D derivatives Chemical class 0.000 claims description 2
- 229940046008 vitamin d Drugs 0.000 claims description 2
- 235000008939 whole milk Nutrition 0.000 claims description 2
- 239000012138 yeast extract Substances 0.000 claims description 2
- 241000209140 Triticum Species 0.000 claims 2
- YEFOAORQXAOVJQ-RZFZLAGVSA-N schisandrol a Chemical compound C1[C@H](C)[C@@](C)(O)CC2=CC(OC)=C(OC)C(OC)=C2C2=C1C=C(OC)C(OC)=C2OC YEFOAORQXAOVJQ-RZFZLAGVSA-N 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 46
- 239000003814 drug Substances 0.000 abstract description 37
- 206010012601 diabetes mellitus Diseases 0.000 abstract description 30
- 229940079593 drug Drugs 0.000 abstract description 30
- 239000008280 blood Substances 0.000 abstract description 24
- 210000004369 blood Anatomy 0.000 abstract description 24
- 235000000346 sugar Nutrition 0.000 abstract description 24
- 201000010099 disease Diseases 0.000 abstract description 15
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 15
- 230000036772 blood pressure Effects 0.000 abstract description 8
- 239000004615 ingredient Substances 0.000 abstract description 8
- 230000004531 blood pressure lowering effect Effects 0.000 abstract description 7
- 235000015468 Lycium chinense Nutrition 0.000 abstract description 4
- 235000008422 Schisandra chinensis Nutrition 0.000 abstract description 4
- 240000006079 Schisandra chinensis Species 0.000 abstract description 4
- 235000016709 nutrition Nutrition 0.000 abstract description 4
- 244000291564 Allium cepa Species 0.000 abstract description 3
- 235000015459 Lycium barbarum Nutrition 0.000 abstract description 3
- 230000035764 nutrition Effects 0.000 abstract description 3
- 206010020751 Hypersensitivity Diseases 0.000 abstract description 2
- 230000007815 allergy Effects 0.000 abstract description 2
- 244000241838 Lycium barbarum Species 0.000 abstract 1
- 244000061176 Nicotiana tabacum Species 0.000 abstract 1
- 235000002637 Nicotiana tabacum Nutrition 0.000 abstract 1
- 241000593989 Scardinius erythrophthalmus Species 0.000 abstract 1
- 208000026935 allergic disease Diseases 0.000 abstract 1
- 230000000208 anti-hepatic effect Effects 0.000 abstract 1
- 240000007594 Oryza sativa Species 0.000 description 10
- 235000007164 Oryza sativa Nutrition 0.000 description 10
- 235000013399 edible fruits Nutrition 0.000 description 10
- 235000009566 rice Nutrition 0.000 description 10
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 9
- 235000010469 Glycine max Nutrition 0.000 description 9
- 244000068988 Glycine max Species 0.000 description 9
- 239000008103 glucose Substances 0.000 description 9
- 239000002253 acid Substances 0.000 description 8
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 8
- 235000013305 food Nutrition 0.000 description 8
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 description 8
- 235000019640 taste Nutrition 0.000 description 8
- 244000269722 Thea sinensis Species 0.000 description 7
- 235000019197 fats Nutrition 0.000 description 7
- 230000002218 hypoglycaemic effect Effects 0.000 description 7
- 229920001202 Inulin Polymers 0.000 description 6
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 6
- LGJMUZUPVCAVPU-UHFFFAOYSA-N beta-Sitostanol Natural products C1CC2CC(O)CCC2(C)C2C1C1CCC(C(C)CCC(CC)C(C)C)C1(C)CC2 LGJMUZUPVCAVPU-UHFFFAOYSA-N 0.000 description 6
- NTKNGUAZSFAKEE-UHFFFAOYSA-N capillarisin Chemical compound C=1C(=O)C2=C(O)C(OC)=C(O)C=C2OC=1OC1=CC=C(O)C=C1 NTKNGUAZSFAKEE-UHFFFAOYSA-N 0.000 description 6
- KWIUHFFTVRNATP-UHFFFAOYSA-N glycine betaine Chemical compound C[N+](C)(C)CC([O-])=O KWIUHFFTVRNATP-UHFFFAOYSA-N 0.000 description 6
- JYJIGFIDKWBXDU-MNNPPOADSA-N inulin Chemical group O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)OC[C@]1(OC[C@]2(OC[C@]3(OC[C@]4(OC[C@]5(OC[C@]6(OC[C@]7(OC[C@]8(OC[C@]9(OC[C@]%10(OC[C@]%11(OC[C@]%12(OC[C@]%13(OC[C@]%14(OC[C@]%15(OC[C@]%16(OC[C@]%17(OC[C@]%18(OC[C@]%19(OC[C@]%20(OC[C@]%21(OC[C@]%22(OC[C@]%23(OC[C@]%24(OC[C@]%25(OC[C@]%26(OC[C@]%27(OC[C@]%28(OC[C@]%29(OC[C@]%30(OC[C@]%31(OC[C@]%32(OC[C@]%33(OC[C@]%34(OC[C@]%35(OC[C@]%36(O[C@@H]%37[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O%37)O)[C@H]([C@H](O)[C@@H](CO)O%36)O)[C@H]([C@H](O)[C@@H](CO)O%35)O)[C@H]([C@H](O)[C@@H](CO)O%34)O)[C@H]([C@H](O)[C@@H](CO)O%33)O)[C@H]([C@H](O)[C@@H](CO)O%32)O)[C@H]([C@H](O)[C@@H](CO)O%31)O)[C@H]([C@H](O)[C@@H](CO)O%30)O)[C@H]([C@H](O)[C@@H](CO)O%29)O)[C@H]([C@H](O)[C@@H](CO)O%28)O)[C@H]([C@H](O)[C@@H](CO)O%27)O)[C@H]([C@H](O)[C@@H](CO)O%26)O)[C@H]([C@H](O)[C@@H](CO)O%25)O)[C@H]([C@H](O)[C@@H](CO)O%24)O)[C@H]([C@H](O)[C@@H](CO)O%23)O)[C@H]([C@H](O)[C@@H](CO)O%22)O)[C@H]([C@H](O)[C@@H](CO)O%21)O)[C@H]([C@H](O)[C@@H](CO)O%20)O)[C@H]([C@H](O)[C@@H](CO)O%19)O)[C@H]([C@H](O)[C@@H](CO)O%18)O)[C@H]([C@H](O)[C@@H](CO)O%17)O)[C@H]([C@H](O)[C@@H](CO)O%16)O)[C@H]([C@H](O)[C@@H](CO)O%15)O)[C@H]([C@H](O)[C@@H](CO)O%14)O)[C@H]([C@H](O)[C@@H](CO)O%13)O)[C@H]([C@H](O)[C@@H](CO)O%12)O)[C@H]([C@H](O)[C@@H](CO)O%11)O)[C@H]([C@H](O)[C@@H](CO)O%10)O)[C@H]([C@H](O)[C@@H](CO)O9)O)[C@H]([C@H](O)[C@@H](CO)O8)O)[C@H]([C@H](O)[C@@H](CO)O7)O)[C@H]([C@H](O)[C@@H](CO)O6)O)[C@H]([C@H](O)[C@@H](CO)O5)O)[C@H]([C@H](O)[C@@H](CO)O4)O)[C@H]([C@H](O)[C@@H](CO)O3)O)[C@H]([C@H](O)[C@@H](CO)O2)O)[C@@H](O)[C@H](O)[C@@H](CO)O1 JYJIGFIDKWBXDU-MNNPPOADSA-N 0.000 description 6
- 229940029339 inulin Drugs 0.000 description 6
- 239000002075 main ingredient Substances 0.000 description 6
- 230000002265 prevention Effects 0.000 description 6
- 235000018102 proteins Nutrition 0.000 description 6
- 102000004169 proteins and genes Human genes 0.000 description 6
- 108090000623 proteins and genes Proteins 0.000 description 6
- 230000001256 tonic effect Effects 0.000 description 6
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 5
- 229920002472 Starch Polymers 0.000 description 5
- 229940024606 amino acid Drugs 0.000 description 5
- 235000001014 amino acid Nutrition 0.000 description 5
- 150000001413 amino acids Chemical class 0.000 description 5
- 239000011575 calcium Substances 0.000 description 5
- 229910052791 calcium Inorganic materials 0.000 description 5
- 235000001465 calcium Nutrition 0.000 description 5
- 150000001720 carbohydrates Chemical class 0.000 description 5
- 235000014633 carbohydrates Nutrition 0.000 description 5
- 239000000284 extract Substances 0.000 description 5
- 239000000835 fiber Substances 0.000 description 5
- 235000009569 green tea Nutrition 0.000 description 5
- 230000006872 improvement Effects 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- 239000013535 sea water Substances 0.000 description 5
- 235000019698 starch Nutrition 0.000 description 5
- 239000008107 starch Substances 0.000 description 5
- ZJSJQWDXAYNLNS-UHFFFAOYSA-N (+) pinoresinol-4,4'-di-O-beta-D-glucopyranoside Natural products COC1=CC(C2C3C(C(OC3)C=3C=C(OC)C(OC4C(C(O)C(O)C(CO)O4)O)=CC=3)CO2)=CC=C1OC1OC(CO)C(O)C(O)C1O ZJSJQWDXAYNLNS-UHFFFAOYSA-N 0.000 description 4
- 102000004877 Insulin Human genes 0.000 description 4
- 108090001061 Insulin Proteins 0.000 description 4
- 230000009471 action Effects 0.000 description 4
- NJKOMDUNNDKEAI-UHFFFAOYSA-N beta-sitosterol Natural products CCC(CCC(C)C1CCC2(C)C3CC=C4CC(O)CCC4C3CCC12C)C(C)C NJKOMDUNNDKEAI-UHFFFAOYSA-N 0.000 description 4
- 235000012000 cholesterol Nutrition 0.000 description 4
- 229940125396 insulin Drugs 0.000 description 4
- IGWDEVSBEKYORK-UHFFFAOYSA-N isoimperatorin Chemical compound O1C(=O)C=CC2=C1C=C1OC=CC1=C2OCC=C(C)C IGWDEVSBEKYORK-UHFFFAOYSA-N 0.000 description 4
- 239000002245 particle Substances 0.000 description 4
- GUAFOGOEJLSQBT-UHFFFAOYSA-N scoparone Chemical compound C1=CC(=O)OC2=C1C=C(OC)C(OC)=C2 GUAFOGOEJLSQBT-UHFFFAOYSA-N 0.000 description 4
- KZJWDPNRJALLNS-VJSFXXLFSA-N sitosterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CC[C@@H](CC)C(C)C)[C@@]1(C)CC2 KZJWDPNRJALLNS-VJSFXXLFSA-N 0.000 description 4
- 229950005143 sitosterol Drugs 0.000 description 4
- VZGDMQKNWNREIO-UHFFFAOYSA-N tetrachloromethane Chemical compound ClC(Cl)(Cl)Cl VZGDMQKNWNREIO-UHFFFAOYSA-N 0.000 description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
- FFDULTAFAQRACT-NYYYOYJKSA-N (-)-syringaresinol O,O'-bis(beta-D-glucoside) Chemical compound COC1=CC([C@H]2[C@H]3[C@H]([C@@H](OC3)C=3C=C(OC)C(O[C@H]4[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O4)O)=C(OC)C=3)CO2)=CC(OC)=C1O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O FFDULTAFAQRACT-NYYYOYJKSA-N 0.000 description 3
- 244000000626 Daucus carota Species 0.000 description 3
- 235000002767 Daucus carota Nutrition 0.000 description 3
- BGXFQDFSVDZUIW-UHFFFAOYSA-N Decursinol Natural products O1C(=O)C=CC2=C1C=C1OC(C)(C)C(O)CC1=C2 BGXFQDFSVDZUIW-UHFFFAOYSA-N 0.000 description 3
- 241000196324 Embryophyta Species 0.000 description 3
- 108090000790 Enzymes Proteins 0.000 description 3
- 102000004190 Enzymes Human genes 0.000 description 3
- 244000241872 Lycium chinense Species 0.000 description 3
- 241000283973 Oryctolagus cuniculus Species 0.000 description 3
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 3
- 208000004880 Polyuria Diseases 0.000 description 3
- 238000010521 absorption reaction Methods 0.000 description 3
- 229930013930 alkaloid Natural products 0.000 description 3
- 235000011399 aloe vera Nutrition 0.000 description 3
- 230000000844 anti-bacterial effect Effects 0.000 description 3
- 230000003178 anti-diabetic effect Effects 0.000 description 3
- 230000003110 anti-inflammatory effect Effects 0.000 description 3
- 229940076810 beta sitosterol Drugs 0.000 description 3
- 239000003795 chemical substances by application Substances 0.000 description 3
- 230000001684 chronic effect Effects 0.000 description 3
- 235000015165 citric acid Nutrition 0.000 description 3
- 235000009508 confectionery Nutrition 0.000 description 3
- BGXFQDFSVDZUIW-LBPRGKRZSA-N decursinol Chemical compound O1C(=O)C=CC2=C1C=C1OC(C)(C)[C@@H](O)CC1=C2 BGXFQDFSVDZUIW-LBPRGKRZSA-N 0.000 description 3
- 230000006870 function Effects 0.000 description 3
- 230000002401 inhibitory effect Effects 0.000 description 3
- 229910052500 inorganic mineral Inorganic materials 0.000 description 3
- 229910052742 iron Inorganic materials 0.000 description 3
- 229960003284 iron Drugs 0.000 description 3
- 235000020332 matcha tea Nutrition 0.000 description 3
- 239000011707 mineral Substances 0.000 description 3
- 235000010755 mineral Nutrition 0.000 description 3
- 230000000144 pharmacologic effect Effects 0.000 description 3
- 239000011574 phosphorus Substances 0.000 description 3
- 229910052698 phosphorus Inorganic materials 0.000 description 3
- 235000014786 phosphorus Nutrition 0.000 description 3
- 150000003839 salts Chemical class 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- KDYFGRWQOYBRFD-UHFFFAOYSA-N succinic acid Chemical compound OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 description 3
- JZRWCGZRTZMZEH-UHFFFAOYSA-N thiamine Chemical compound CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N JZRWCGZRTZMZEH-UHFFFAOYSA-N 0.000 description 3
- 210000002700 urine Anatomy 0.000 description 3
- 239000000341 volatile oil Substances 0.000 description 3
- KWGRBVOPPLSCSI-WPRPVWTQSA-N (-)-ephedrine Chemical compound CN[C@@H](C)[C@H](O)C1=CC=CC=C1 KWGRBVOPPLSCSI-WPRPVWTQSA-N 0.000 description 2
- OILXMJHPFNGGTO-UHFFFAOYSA-N (22E)-(24xi)-24-methylcholesta-5,22-dien-3beta-ol Natural products C1C=C2CC(O)CCC2(C)C2C1C1CCC(C(C)C=CC(C)C(C)C)C1(C)CC2 OILXMJHPFNGGTO-UHFFFAOYSA-N 0.000 description 2
- BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 description 2
- AWBXMNYCXOZEMM-UHFFFAOYSA-N 1-hexa-2,4-diynyl-2-methoxybenzene Chemical compound COC1=CC=CC=C1CC#CC#CC AWBXMNYCXOZEMM-UHFFFAOYSA-N 0.000 description 2
- JVLBOZIUMGNKQW-UHFFFAOYSA-N 1-hydroxy-3,4-seco-4(23),20(29)-lupadien-3,11-olid-28-oic acid 28-O-alpha-L-rhamnopyranosyl-(1->4)-O-beta-D-glucopyranosyl-(1->6)-O-beta-D-glucopyranoside Natural products OC1C(O)C(O)C(C)OC1OC1C(CO)OC(OCC2C(C(O)C(O)C(OC(=O)C34C(C(CC3)C(C)=C)C3C(C5(C)CCC(C6(C)C(O)CC(=O)OC(C56)C3)C(C)=C)(C)CC4)O2)O)C(O)C1O JVLBOZIUMGNKQW-UHFFFAOYSA-N 0.000 description 2
- MSWZFWKMSRAUBD-GASJEMHNSA-N 2-amino-2-deoxy-D-galactopyranose Chemical compound N[C@H]1C(O)O[C@H](CO)[C@H](O)[C@@H]1O MSWZFWKMSRAUBD-GASJEMHNSA-N 0.000 description 2
- HFRZSVYKDDZRQY-AATRIKPKSA-N 3-Hydroxy-beta-ionone Chemical compound CC(=O)\C=C\C1=C(C)CC(O)CC1(C)C HFRZSVYKDDZRQY-AATRIKPKSA-N 0.000 description 2
- LICNQDPDQQOXCU-FYJFLYSWSA-N 3-Hydroxy-beta-ionone Natural products CC(=O)\C=C\C1=C(C)[C@@H](O)CCC1(C)C LICNQDPDQQOXCU-FYJFLYSWSA-N 0.000 description 2
- ZPSAEGUNYMEKBP-UHFFFAOYSA-N 5-Isopentenyloxy-psoralen Natural products CC(C)C=COc1c2C=CC(=O)Oc2cc3occc13 ZPSAEGUNYMEKBP-UHFFFAOYSA-N 0.000 description 2
- OQMZNAMGEHIHNN-UHFFFAOYSA-N 7-Dehydrostigmasterol Natural products C1C(O)CCC2(C)C(CCC3(C(C(C)C=CC(CC)C(C)C)CCC33)C)C3=CC=C21 OQMZNAMGEHIHNN-UHFFFAOYSA-N 0.000 description 2
- LULLNJMMQHXPDK-UHFFFAOYSA-N Acanthoside D Natural products COc1cc(cc(OC)c1OC2OC(CO)C(O)C(O)C2O)C3OCC4(C)C(OCC34C)c5cc(OC)c(OC6OC(CO)C(O)C(O)C6O)c(OC)c5 LULLNJMMQHXPDK-UHFFFAOYSA-N 0.000 description 2
- BEYIWVKWKJROGZ-UHFFFAOYSA-N Alloimperatorin Natural products O1C(=O)C=CC2=C1C(O)=C1OC=CC1=C2OCC=C(C)C BEYIWVKWKJROGZ-UHFFFAOYSA-N 0.000 description 2
- 241001116389 Aloe Species 0.000 description 2
- 241000208838 Asteraceae Species 0.000 description 2
- 201000001320 Atherosclerosis Diseases 0.000 description 2
- WWNYBNQWIHBNIE-UHFFFAOYSA-N Capillanol Chemical compound CC(O)CC#CCC1=CC=CC=C1 WWNYBNQWIHBNIE-UHFFFAOYSA-N 0.000 description 2
- WIDAUXGFFXJZKU-HVLVMTFESA-N Chiisanoside Natural products C[C@@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](OC[C@H]3O[C@@H](OC(=O)[C@]45CC[C@H]([C@@H]4[C@H]6C[C@H]7OC(=O)C[C@@H](O)[C@@H]8[C@@H](CC[C@](C)([C@H]78)[C@]6(C)CC5)C(=C)C)C(=C)C)[C@H](O)[C@@H](O)[C@@H]3O)O[C@@H]2CO)[C@H](O)[C@H](O)[C@H]1O WIDAUXGFFXJZKU-HVLVMTFESA-N 0.000 description 2
- DPQCZNIGGNJGTD-UHFFFAOYSA-N Chloride-(??)-2-Methylpentanoic acid Natural products CCCCCCC=CCCCCCCCCCC(=O)OC(C)C(C)OC(=O)CCCCCCCC=CCCCCCC DPQCZNIGGNJGTD-UHFFFAOYSA-N 0.000 description 2
- DPQCZNIGGNJGTD-MVCBGFDASA-N Coixenolide Chemical compound CCCCCC\C=C\CCCCCCCCCC(=O)O[C@@H](C)[C@@H](C)OC(=O)CCCCCCC\C=C/CCCCCC DPQCZNIGGNJGTD-MVCBGFDASA-N 0.000 description 2
- MKMCJLMBVKHUMS-UHFFFAOYSA-N Coixol Chemical compound COC1=CC=C2NC(=O)OC2=C1 MKMCJLMBVKHUMS-UHFFFAOYSA-N 0.000 description 2
- 235000019750 Crude protein Nutrition 0.000 description 2
- CUKSFECWKQBVED-INIZCTEOSA-N Decursin Chemical compound C1=CC(=O)OC2=C1C=C1C[C@H](OC(=O)C=C(C)C)C(C)(C)OC1=C2 CUKSFECWKQBVED-INIZCTEOSA-N 0.000 description 2
- 208000030453 Drug-Related Side Effects and Adverse reaction Diseases 0.000 description 2
- FFDULTAFAQRACT-MWBGVTEFSA-N Eleutheroside E Natural products COc1cc(cc(OC)c1O[C@H]2O[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]2O)[C@@H]3OC[C@H]4[C@H]3CO[C@@H]4c5cc(OC)c(O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)c(OC)c5 FFDULTAFAQRACT-MWBGVTEFSA-N 0.000 description 2
- CUKSFECWKQBVED-UHFFFAOYSA-N Grandivittin Natural products C1=CC(=O)OC2=C1C=C1CC(OC(=O)C=C(C)C)C(C)(C)OC1=C2 CUKSFECWKQBVED-UHFFFAOYSA-N 0.000 description 2
- 235000003230 Helianthus tuberosus Nutrition 0.000 description 2
- 240000008892 Helianthus tuberosus Species 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
- 208000031226 Hyperlipidaemia Diseases 0.000 description 2
- KGGUASRIGLRPAX-UHFFFAOYSA-N Meranzin hydrate Natural products C1=CC(=O)OC2=C(CC(O)C(C)(C)O)C(OC)=CC=C21 KGGUASRIGLRPAX-UHFFFAOYSA-N 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
- 241001424383 Moullava spicata Species 0.000 description 2
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 description 2
- HXCGUCZXPFBNRD-QVYYAULWSA-N Nodakenin Natural products O(C(C)(C)[C@@H]1Oc2c(cc3c(OC(=O)C=C3)c2)C1)[C@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 HXCGUCZXPFBNRD-QVYYAULWSA-N 0.000 description 2
- HXCGUCZXPFBNRD-DNLMCPORSA-N Nodakenin Chemical compound CC(C)([C@@H]1OC2=CC=3OC(=O)C=CC=3C=C2C1)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O HXCGUCZXPFBNRD-DNLMCPORSA-N 0.000 description 2
- 208000008589 Obesity Diseases 0.000 description 2
- 206010033799 Paralysis Diseases 0.000 description 2
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 2
- 206010037660 Pyrexia Diseases 0.000 description 2
- KAESVJOAVNADME-UHFFFAOYSA-N Pyrrole Chemical compound C=1C=CNC=1 KAESVJOAVNADME-UHFFFAOYSA-N 0.000 description 2
- 241000220324 Pyrus Species 0.000 description 2
- 241001092459 Rubus Species 0.000 description 2
- UFCGDBKFOKKVAC-DSASHONVSA-N Schisantherin A Chemical compound O([C@H]1C=2C=C(C(=C(OC)C=2C2=C(OC)C=3OCOC=3C=C2C[C@H](C)[C@@]1(O)C)OC)OC)C(=O)C1=CC=CC=C1 UFCGDBKFOKKVAC-DSASHONVSA-N 0.000 description 2
- 244000098338 Triticum aestivum Species 0.000 description 2
- HZYXFRGVBOPPNZ-UHFFFAOYSA-N UNPD88870 Natural products C1C=C2CC(O)CCC2(C)C2C1C1CCC(C(C)=CCC(CC)C(C)C)C1(C)CC2 HZYXFRGVBOPPNZ-UHFFFAOYSA-N 0.000 description 2
- NOVFAHFRCMKDBE-UHFFFAOYSA-N Ulmosid Natural products OCC1OC(OCC2OC(OC3OC=CC4C(O)C=C(CO)C34)C(O)C(O)C2O)C(O)C(O)C1O NOVFAHFRCMKDBE-UHFFFAOYSA-N 0.000 description 2
- NOVFAHFRCMKDBE-WWPUYSJASA-N Ulmoside Natural products O(C[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](O[C@@H]2OC=C[C@@H]3[C@@H](O)C=C(CO)[C@@H]23)O1)[C@H]1[C@@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 NOVFAHFRCMKDBE-WWPUYSJASA-N 0.000 description 2
- 229930192007 acanthoside Natural products 0.000 description 2
- UCTWMZQNUQWSLP-UHFFFAOYSA-N adrenaline Chemical compound CNCC(O)C1=CC=C(O)C(O)=C1 UCTWMZQNUQWSLP-UHFFFAOYSA-N 0.000 description 2
- HIMXGTXNXJYFGB-UHFFFAOYSA-N alloxan Chemical compound O=C1NC(=O)C(=O)C(=O)N1 HIMXGTXNXJYFGB-UHFFFAOYSA-N 0.000 description 2
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 description 2
- 208000007502 anemia Diseases 0.000 description 2
- 230000001754 anti-pyretic effect Effects 0.000 description 2
- 239000003472 antidiabetic agent Substances 0.000 description 2
- 239000002221 antipyretic Substances 0.000 description 2
- 235000010323 ascorbic acid Nutrition 0.000 description 2
- 229960005070 ascorbic acid Drugs 0.000 description 2
- 239000011668 ascorbic acid Substances 0.000 description 2
- MSWZFWKMSRAUBD-UHFFFAOYSA-N beta-D-galactosamine Natural products NC1C(O)OC(CO)C(O)C1O MSWZFWKMSRAUBD-UHFFFAOYSA-N 0.000 description 2
- 229960003237 betaine Drugs 0.000 description 2
- JVLBOZIUMGNKQW-JBPVHNHLSA-N chiisanoside Chemical compound O[C@@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@H]1O[C@@H]1[C@@H](CO)O[C@@H](OC[C@@H]2[C@H]([C@H](O)[C@@H](O)[C@H](OC(=O)[C@@]34[C@H]([C@@H](CC3)C(C)=C)[C@@H]3[C@@]([C@]5(C)CC[C@H]([C@]6(C)[C@H](O)CC(=O)O[C@@H]([C@@H]56)C3)C(C)=C)(C)CC4)O2)O)[C@H](O)[C@H]1O JVLBOZIUMGNKQW-JBPVHNHLSA-N 0.000 description 2
- OEYIOHPDSNJKLS-UHFFFAOYSA-N choline Chemical compound C[N+](C)(C)CCO OEYIOHPDSNJKLS-UHFFFAOYSA-N 0.000 description 2
- 229960001231 choline Drugs 0.000 description 2
- JXZWWIMXTVJNSF-UHFFFAOYSA-N decursin Natural products CC(=CC(=O)OC1Oc2cc3OC(=O)C=Cc3cc2CC1(C)C)C JXZWWIMXTVJNSF-UHFFFAOYSA-N 0.000 description 2
- 235000021186 dishes Nutrition 0.000 description 2
- 210000003722 extracellular fluid Anatomy 0.000 description 2
- 239000010685 fatty oil Substances 0.000 description 2
- 239000003205 fragrance Substances 0.000 description 2
- BJHIKXHVCXFQLS-UYFOZJQFSA-N fructose group Chemical group OCC(=O)[C@@H](O)[C@H](O)[C@H](O)CO BJHIKXHVCXFQLS-UYFOZJQFSA-N 0.000 description 2
- 150000004676 glycans Chemical class 0.000 description 2
- 229930186755 gomisin Natural products 0.000 description 2
- 235000020256 human milk Nutrition 0.000 description 2
- 210000004251 human milk Anatomy 0.000 description 2
- 201000001421 hyperglycemia Diseases 0.000 description 2
- XKVWLLRDBHAWBL-UHFFFAOYSA-N imperatorin Natural products CC(=CCOc1c2OCCc2cc3C=CC(=O)Oc13)C XKVWLLRDBHAWBL-UHFFFAOYSA-N 0.000 description 2
- OLOOJGVNMBJLLR-UHFFFAOYSA-N imperatorin Chemical compound C1=CC(=O)OC2=C1C=C1C=COC1=C2OCC=C(C)C OLOOJGVNMBJLLR-UHFFFAOYSA-N 0.000 description 2
- 210000000936 intestine Anatomy 0.000 description 2
- 208000017169 kidney disease Diseases 0.000 description 2
- 229930013686 lignan Natural products 0.000 description 2
- 150000005692 lignans Chemical class 0.000 description 2
- 235000009408 lignans Nutrition 0.000 description 2
- 150000002632 lipids Chemical class 0.000 description 2
- 230000003908 liver function Effects 0.000 description 2
- 230000033001 locomotion Effects 0.000 description 2
- 239000001630 malic acid Substances 0.000 description 2
- 235000011090 malic acid Nutrition 0.000 description 2
- HXCGUCZXPFBNRD-UHFFFAOYSA-N nodakenine Natural products C1C2=CC=3C=CC(=O)OC=3C=C2OC1C(C)(C)OC1OC(CO)C(O)C(O)C1O HXCGUCZXPFBNRD-UHFFFAOYSA-N 0.000 description 2
- 235000015097 nutrients Nutrition 0.000 description 2
- 235000020824 obesity Nutrition 0.000 description 2
- SECPZKHBENQXJG-FPLPWBNLSA-N palmitoleic acid Chemical compound CCCCCC\C=C/CCCCCCCC(O)=O SECPZKHBENQXJG-FPLPWBNLSA-N 0.000 description 2
- 210000005037 parasympathetic nerve Anatomy 0.000 description 2
- 230000001575 pathological effect Effects 0.000 description 2
- 231100000614 poison Toxicity 0.000 description 2
- 229920001282 polysaccharide Polymers 0.000 description 2
- 239000005017 polysaccharide Substances 0.000 description 2
- 239000011591 potassium Substances 0.000 description 2
- 229910052700 potassium Inorganic materials 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- HFRZSVYKDDZRQY-UHFFFAOYSA-N rac-3-Hydroxy-beta-ionone Natural products CC(=O)C=CC1=C(C)CC(O)CC1(C)C HFRZSVYKDDZRQY-UHFFFAOYSA-N 0.000 description 2
- 230000001172 regenerating effect Effects 0.000 description 2
- SGAWOGXMMPSZPB-UHFFFAOYSA-N safranal Chemical compound CC1=C(C=O)C(C)(C)CC=C1 SGAWOGXMMPSZPB-UHFFFAOYSA-N 0.000 description 2
- 210000000582 semen Anatomy 0.000 description 2
- 208000017520 skin disease Diseases 0.000 description 2
- RAKOKKNCCBUUMP-UHFFFAOYSA-N stigmastanol trans-ferulate Natural products C1CC2(C)C3CCC4(C)C(C(C)CCC(CC)C(C)C)CCC4C3CCC2CC1OC(=O)C=CC1=CC=C(O)C(OC)=C1 RAKOKKNCCBUUMP-UHFFFAOYSA-N 0.000 description 2
- HCXVJBMSMIARIN-PHZDYDNGSA-N stigmasterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)/C=C/[C@@H](CC)C(C)C)[C@@]1(C)CC2 HCXVJBMSMIARIN-PHZDYDNGSA-N 0.000 description 2
- 229940032091 stigmasterol Drugs 0.000 description 2
- 235000016831 stigmasterol Nutrition 0.000 description 2
- BFDNMXAIBMJLBB-UHFFFAOYSA-N stigmasterol Natural products CCC(C=CC(C)C1CCCC2C3CC=C4CC(O)CCC4(C)C3CCC12C)C(C)C BFDNMXAIBMJLBB-UHFFFAOYSA-N 0.000 description 2
- 150000008163 sugars Chemical class 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical compound NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 description 2
- 239000011573 trace mineral Substances 0.000 description 2
- 235000013619 trace mineral Nutrition 0.000 description 2
- PEYUIKBAABKQKQ-AFHBHXEDSA-N (+)-sesamin Chemical compound C1=C2OCOC2=CC([C@H]2OC[C@H]3[C@@H]2CO[C@@H]3C2=CC=C3OCOC3=C2)=C1 PEYUIKBAABKQKQ-AFHBHXEDSA-N 0.000 description 1
- WEKCEGQSIIQPAQ-IRBNZIFYSA-N (+)-syringaresinol beta-D-glucoside Chemical compound COC1=C(O)C(OC)=CC([C@@H]2[C@@H]3[C@@H]([C@H](OC3)C=3C=C(OC)C(O[C@H]4[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O4)O)=C(OC)C=3)CO2)=C1 WEKCEGQSIIQPAQ-IRBNZIFYSA-N 0.000 description 1
- CMJGAYUQSLJSCR-WACFDSSMSA-N (-)-Hibalactone Natural products C1=C2OCOC2=CC(/C=C2/[C@@H](CC=3C=C4OCOC4=CC=3)COC2=O)=C1 CMJGAYUQSLJSCR-WACFDSSMSA-N 0.000 description 1
- KZJWDPNRJALLNS-VPUBHVLGSA-N (-)-beta-Sitosterol Natural products O[C@@H]1CC=2[C@@](C)([C@@H]3[C@H]([C@H]4[C@@](C)([C@H]([C@H](CC[C@@H](C(C)C)CC)C)CC4)CC3)CC=2)CC1 KZJWDPNRJALLNS-VPUBHVLGSA-N 0.000 description 1
- CSVWWLUMXNHWSU-UHFFFAOYSA-N (22E)-(24xi)-24-ethyl-5alpha-cholest-22-en-3beta-ol Natural products C1CC2CC(O)CCC2(C)C2C1C1CCC(C(C)C=CC(CC)C(C)C)C1(C)CC2 CSVWWLUMXNHWSU-UHFFFAOYSA-N 0.000 description 1
- RGSHXVKKSKRNJG-YEWYEPQMSA-N (2r,3s,4s,6ar,6bs,8as,11r,12r,12as,14br)-3-[(2r,3r,4s,6ar,6bs,8as,11r,12r,12as,14br)-2,3,12-trihydroxy-4,6a,6b,11,12,14b-hexamethyl-8a-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxycarbonyl-1,2,3,4a,5,6,7,8,9,10,11,12a,14,14a-tetradecah Chemical compound O=C([C@]12CC[C@@H](C)[C@@](C)(O)[C@H]1C1=CCC3[C@@]4(C)C[C@@H](O)[C@H]([C@](C4CC[C@@]3(C)[C@]1(C)CC2)(CO)C(O)=O)OC(=O)[C@]1(C)[C@@H](O)[C@H](O)C[C@]2(C)C3CC=C4[C@@]([C@@]3(CCC21)C)(C)CC[C@]1(CC[C@H]([C@@]([C@H]14)(C)O)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O RGSHXVKKSKRNJG-YEWYEPQMSA-N 0.000 description 1
- 125000004204 2-methoxyphenyl group Chemical group [H]C1=C([H])C(*)=C(OC([H])([H])[H])C([H])=C1[H] 0.000 description 1
- KLEXDBGYSOIREE-UHFFFAOYSA-N 24xi-n-propylcholesterol Natural products C1C=C2CC(O)CCC2(C)C2C1C1CCC(C(C)CCC(CCC)C(C)C)C1(C)CC2 KLEXDBGYSOIREE-UHFFFAOYSA-N 0.000 description 1
- HQQTZCPKNZVLFF-UHFFFAOYSA-N 4h-1,2-benzoxazin-3-one Chemical compound C1=CC=C2ONC(=O)CC2=C1 HQQTZCPKNZVLFF-UHFFFAOYSA-N 0.000 description 1
- VNFYMAPAENTMMO-UHFFFAOYSA-N 5-chloro-2-methylquinoline Chemical compound ClC1=CC=CC2=NC(C)=CC=C21 VNFYMAPAENTMMO-UHFFFAOYSA-N 0.000 description 1
- CJIJXIFQYOPWTF-UHFFFAOYSA-N 7-hydroxycoumarin Natural products O1C(=O)C=CC2=CC(O)=CC=C21 CJIJXIFQYOPWTF-UHFFFAOYSA-N 0.000 description 1
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 description 1
- 208000010444 Acidosis Diseases 0.000 description 1
- 229920001817 Agar Polymers 0.000 description 1
- 235000005255 Allium cepa Nutrition 0.000 description 1
- 235000002961 Aloe barbadensis Nutrition 0.000 description 1
- 244000144927 Aloe barbadensis Species 0.000 description 1
- 235000009051 Ambrosia paniculata var. peruviana Nutrition 0.000 description 1
- 244000247812 Amorphophallus rivieri Species 0.000 description 1
- 235000001206 Amorphophallus rivieri Nutrition 0.000 description 1
- 235000018865 Angelica gigas Nutrition 0.000 description 1
- 240000001810 Angelica gigas Species 0.000 description 1
- 240000007087 Apium graveolens Species 0.000 description 1
- 235000015849 Apium graveolens Dulce Group Nutrition 0.000 description 1
- 235000010591 Appio Nutrition 0.000 description 1
- 235000017060 Arachis glabrata Nutrition 0.000 description 1
- 244000105624 Arachis hypogaea Species 0.000 description 1
- 235000010777 Arachis hypogaea Nutrition 0.000 description 1
- 235000018262 Arachis monticola Nutrition 0.000 description 1
- 235000003826 Artemisia Nutrition 0.000 description 1
- 235000003097 Artemisia absinthium Nutrition 0.000 description 1
- 235000017731 Artemisia dracunculus ssp. dracunculus Nutrition 0.000 description 1
- 235000017166 Bambusa arundinacea Nutrition 0.000 description 1
- 235000017491 Bambusa tulda Nutrition 0.000 description 1
- JMGZEFIQIZZSBH-UHFFFAOYSA-N Bioquercetin Natural products CC1OC(OCC(O)C2OC(OC3=C(Oc4cc(O)cc(O)c4C3=O)c5ccc(O)c(O)c5)C(O)C2O)C(O)C(O)C1O JMGZEFIQIZZSBH-UHFFFAOYSA-N 0.000 description 1
- 241000283690 Bos taurus Species 0.000 description 1
- 241000282472 Canis lupus familiaris Species 0.000 description 1
- 244000025254 Cannabis sativa Species 0.000 description 1
- 235000012766 Cannabis sativa ssp. sativa var. sativa Nutrition 0.000 description 1
- 235000012765 Cannabis sativa ssp. sativa var. spontanea Nutrition 0.000 description 1
- 240000004160 Capsicum annuum Species 0.000 description 1
- 235000008534 Capsicum annuum var annuum Nutrition 0.000 description 1
- 235000007862 Capsicum baccatum Nutrition 0.000 description 1
- 235000014112 Cassia mimosoides Nutrition 0.000 description 1
- 244000302899 Cassia mimosoides Species 0.000 description 1
- 235000014036 Castanea Nutrition 0.000 description 1
- 241001070941 Castanea Species 0.000 description 1
- 241001107116 Castanospermum australe Species 0.000 description 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 1
- VYZAMTAEIAYCRO-UHFFFAOYSA-N Chromium Chemical compound [Cr] VYZAMTAEIAYCRO-UHFFFAOYSA-N 0.000 description 1
- 244000223760 Cinnamomum zeylanicum Species 0.000 description 1
- WTEVQBCEXWBHNA-UHFFFAOYSA-N Citral Natural products CC(C)=CCCC(C)=CC=O WTEVQBCEXWBHNA-UHFFFAOYSA-N 0.000 description 1
- LPZCCMIISIBREI-MTFRKTCUSA-N Citrostadienol Natural products CC=C(CC[C@@H](C)[C@H]1CC[C@H]2C3=CC[C@H]4[C@H](C)[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C)C(C)C LPZCCMIISIBREI-MTFRKTCUSA-N 0.000 description 1
- 241001454694 Clupeiformes Species 0.000 description 1
- 240000007154 Coffea arabica Species 0.000 description 1
- 206010010774 Constipation Diseases 0.000 description 1
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
- 240000008067 Cucumis sativus Species 0.000 description 1
- 235000010799 Cucumis sativus var sativus Nutrition 0.000 description 1
- XFXPMWWXUTWYJX-UHFFFAOYSA-N Cyanide Chemical compound N#[C-] XFXPMWWXUTWYJX-UHFFFAOYSA-N 0.000 description 1
- RFSUNEUAIZKAJO-VRPWFDPXSA-N D-Fructose Natural products OC[C@H]1OC(O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-VRPWFDPXSA-N 0.000 description 1
- 235000012040 Dahlia pinnata Nutrition 0.000 description 1
- 244000033273 Dahlia variabilis Species 0.000 description 1
- 101000831205 Danio rerio Dynein axonemal assembly factor 11 Proteins 0.000 description 1
- SYRXQLPUGCYKFH-UHFFFAOYSA-N Decursidin Natural products O1C(=O)C=CC2=C1C=C1OC(C)(C)C(OC(=O)C=C(C)C)C(OC(=O)C=C(C)C)C1=C2 SYRXQLPUGCYKFH-UHFFFAOYSA-N 0.000 description 1
- ARVGMISWLZPBCH-UHFFFAOYSA-N Dehydro-beta-sitosterol Natural products C1C(O)CCC2(C)C(CCC3(C(C(C)CCC(CC)C(C)C)CCC33)C)C3=CC=C21 ARVGMISWLZPBCH-UHFFFAOYSA-N 0.000 description 1
- ZZGANZXITREHOP-UHFFFAOYSA-N Desmethyl-capillen Natural products C#CC#CCC1=CC=CC=C1 ZZGANZXITREHOP-UHFFFAOYSA-N 0.000 description 1
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 description 1
- 208000001380 Diabetic Ketoacidosis Diseases 0.000 description 1
- 206010012735 Diarrhoea Diseases 0.000 description 1
- LCGLNKUTAGEVQW-UHFFFAOYSA-N Dimethyl ether Chemical compound COC LCGLNKUTAGEVQW-UHFFFAOYSA-N 0.000 description 1
- 235000002722 Dioscorea batatas Nutrition 0.000 description 1
- 240000008955 Dioscorea japonica Species 0.000 description 1
- 235000005251 Dioscorea japonica Nutrition 0.000 description 1
- 240000001811 Dioscorea oppositifolia Species 0.000 description 1
- 244000281702 Dioscorea villosa Species 0.000 description 1
- 102100024282 Dynein axonemal assembly factor 11 Human genes 0.000 description 1
- 241001094255 Elytraria Species 0.000 description 1
- 241000208688 Eucommia Species 0.000 description 1
- 108010022355 Fibroins Proteins 0.000 description 1
- 241000628997 Flos Species 0.000 description 1
- 206010016952 Food poisoning Diseases 0.000 description 1
- 208000019331 Foodborne disease Diseases 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 102000051325 Glucagon Human genes 0.000 description 1
- 108060003199 Glucagon Proteins 0.000 description 1
- 229920001503 Glucan Polymers 0.000 description 1
- 208000002705 Glucose Intolerance Diseases 0.000 description 1
- 206010018429 Glucose tolerance impaired Diseases 0.000 description 1
- WHUUTDBJXJRKMK-UHFFFAOYSA-N Glutamic acid Natural products OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 description 1
- 229920002527 Glycogen Polymers 0.000 description 1
- 206010018473 Glycosuria Diseases 0.000 description 1
- 208000024659 Hemostatic disease Diseases 0.000 description 1
- 241001559542 Hippocampus hippocampus Species 0.000 description 1
- 101000831210 Homo sapiens Dynein axonemal assembly factor 11 Proteins 0.000 description 1
- 240000005979 Hordeum vulgare Species 0.000 description 1
- 235000007340 Hordeum vulgare Nutrition 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 208000013016 Hypoglycemia Diseases 0.000 description 1
- 208000001953 Hypotension Diseases 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 206010022998 Irritability Diseases 0.000 description 1
- CMJGAYUQSLJSCR-UUASQNMZSA-N Isohabilactone Natural products C1=C2OCOC2=CC(/C=C2/C(CC=3C=C4OCOC4=CC=3)COC2=O)=C1 CMJGAYUQSLJSCR-UUASQNMZSA-N 0.000 description 1
- 206010023126 Jaundice Diseases 0.000 description 1
- 208000007976 Ketosis Diseases 0.000 description 1
- 229920002752 Konjac Polymers 0.000 description 1
- ONIBWKKTOPOVIA-BYPYZUCNSA-N L-Proline Chemical compound OC(=O)[C@@H]1CCCN1 ONIBWKKTOPOVIA-BYPYZUCNSA-N 0.000 description 1
- CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 description 1
- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 description 1
- KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 description 1
- OUYCCCASQSFEME-QMMMGPOBSA-N L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-QMMMGPOBSA-N 0.000 description 1
- 240000008415 Lactuca sativa Species 0.000 description 1
- 241000408747 Lepomis gibbosus Species 0.000 description 1
- 241000234280 Liliaceae Species 0.000 description 1
- 241000234435 Lilium Species 0.000 description 1
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 description 1
- 239000004472 Lysine Substances 0.000 description 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
- YKVWPZJHENXDAJ-VOTSOKGWSA-N Megastigmatrienone Chemical compound CC1=CC(=O)CC(C)(C)C1\C=C\C=C YKVWPZJHENXDAJ-VOTSOKGWSA-N 0.000 description 1
- 235000006508 Nelumbo nucifera Nutrition 0.000 description 1
- 240000002853 Nelumbo nucifera Species 0.000 description 1
- 208000012902 Nervous system disease Diseases 0.000 description 1
- 208000025966 Neurological disease Diseases 0.000 description 1
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 description 1
- ACPMYIIORVILBG-UHFFFAOYSA-N Norcapillene Chemical compound CC#CC#CC1=CC=CC=C1 ACPMYIIORVILBG-UHFFFAOYSA-N 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 235000021319 Palmitoleic acid Nutrition 0.000 description 1
- 235000004347 Perilla Nutrition 0.000 description 1
- 244000124853 Perilla frutescens Species 0.000 description 1
- 241000199919 Phaeophyceae Species 0.000 description 1
- 244000082204 Phyllostachys viridis Species 0.000 description 1
- 235000015334 Phyllostachys viridis Nutrition 0.000 description 1
- 235000008331 Pinus X rigitaeda Nutrition 0.000 description 1
- 241000018646 Pinus brutia Species 0.000 description 1
- 235000011613 Pinus brutia Nutrition 0.000 description 1
- 241000037831 Polygonatum sibiricum Species 0.000 description 1
- ONIBWKKTOPOVIA-UHFFFAOYSA-N Proline Natural products OC(=O)C1CCCN1 ONIBWKKTOPOVIA-UHFFFAOYSA-N 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 235000014443 Pyrus communis Nutrition 0.000 description 1
- 208000004756 Respiratory Insufficiency Diseases 0.000 description 1
- 206010038678 Respiratory depression Diseases 0.000 description 1
- 208000017442 Retinal disease Diseases 0.000 description 1
- 240000008301 Rhynchosia minima Species 0.000 description 1
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 description 1
- 240000003829 Sorghum propinquum Species 0.000 description 1
- 235000011684 Sorghum saccharatum Nutrition 0.000 description 1
- 235000009337 Spinacia oleracea Nutrition 0.000 description 1
- 244000300264 Spinacia oleracea Species 0.000 description 1
- 241000191967 Staphylococcus aureus Species 0.000 description 1
- 229930182558 Sterol Natural products 0.000 description 1
- ZSJLQEPLLKMAKR-UHFFFAOYSA-N Streptozotocin Natural products O=NN(C)C(=O)NC1C(O)OC(CO)C(O)C1O ZSJLQEPLLKMAKR-UHFFFAOYSA-N 0.000 description 1
- 206010042220 Stress ulcer Diseases 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 description 1
- GUGOEEXESWIERI-UHFFFAOYSA-N Terfenadine Chemical compound C1=CC(C(C)(C)C)=CC=C1C(O)CCCN1CCC(C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 GUGOEEXESWIERI-UHFFFAOYSA-N 0.000 description 1
- 235000006468 Thea sinensis Nutrition 0.000 description 1
- 241001467018 Typhis Species 0.000 description 1
- 235000011453 Vigna umbellata Nutrition 0.000 description 1
- 240000001417 Vigna umbellata Species 0.000 description 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 1
- 210000001015 abdomen Anatomy 0.000 description 1
- 210000000683 abdominal cavity Anatomy 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 230000005856 abnormality Effects 0.000 description 1
- PXKVPZNSQPPOGU-LFCYPEIASA-N acanthoside B Natural products COc1cc(cc(O)c1O[C@@H]2O[C@H](CO[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@@H](O)[C@H](O)[C@H]2O)[C@@H]4OC[C@H]5[C@@H]4CO[C@@H]5c6cc(OC)c(O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)c(OC)c6 PXKVPZNSQPPOGU-LFCYPEIASA-N 0.000 description 1
- OIPILFWXSMYKGL-UHFFFAOYSA-N acetylcholine Chemical compound CC(=O)OCC[N+](C)(C)C OIPILFWXSMYKGL-UHFFFAOYSA-N 0.000 description 1
- 229960004373 acetylcholine Drugs 0.000 description 1
- 230000007950 acidosis Effects 0.000 description 1
- 208000026545 acidosis disease Diseases 0.000 description 1
- 238000001467 acupuncture Methods 0.000 description 1
- 230000006978 adaptation Effects 0.000 description 1
- 239000008272 agar Substances 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 229940008075 allyl sulfide Drugs 0.000 description 1
- 150000001412 amines Chemical class 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 235000019513 anchovy Nutrition 0.000 description 1
- 238000010171 animal model Methods 0.000 description 1
- 239000005557 antagonist Substances 0.000 description 1
- 230000002429 anti-coagulating effect Effects 0.000 description 1
- 230000002391 anti-complement effect Effects 0.000 description 1
- 230000001387 anti-histamine Effects 0.000 description 1
- 230000000845 anti-microbial effect Effects 0.000 description 1
- 230000000259 anti-tumor effect Effects 0.000 description 1
- 108010008730 anticomplement Proteins 0.000 description 1
- 239000000739 antihistaminic agent Substances 0.000 description 1
- 235000009052 artemisia Nutrition 0.000 description 1
- 239000001138 artemisia absinthium Substances 0.000 description 1
- 125000003118 aryl group Chemical group 0.000 description 1
- 229960005261 aspartic acid Drugs 0.000 description 1
- 235000003704 aspartic acid Nutrition 0.000 description 1
- 235000008452 baby food Nutrition 0.000 description 1
- 239000011425 bamboo Substances 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- MJVXAPPOFPTTCA-UHFFFAOYSA-N beta-Sistosterol Natural products CCC(CCC(C)C1CCC2C3CC=C4C(C)C(O)CCC4(C)C3CCC12C)C(C)C MJVXAPPOFPTTCA-UHFFFAOYSA-N 0.000 description 1
- OQFSQFPPLPISGP-UHFFFAOYSA-N beta-carboxyaspartic acid Natural products OC(=O)C(N)C(C(O)=O)C(O)=O OQFSQFPPLPISGP-UHFFFAOYSA-N 0.000 description 1
- 230000010234 biliary secretion Effects 0.000 description 1
- 235000021279 black bean Nutrition 0.000 description 1
- 235000007215 black sesame Nutrition 0.000 description 1
- 235000020279 black tea Nutrition 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- GHAFORRTMVIXHS-UHFFFAOYSA-L bromosulfophthalein sodium Chemical compound [Na+].[Na+].C1=C(S([O-])(=O)=O)C(O)=CC=C1C1(C=2C=C(C(O)=CC=2)S([O-])(=O)=O)C(C(Br)=C(Br)C(Br)=C2Br)=C2C(=O)O1 GHAFORRTMVIXHS-UHFFFAOYSA-L 0.000 description 1
- 235000009120 camo Nutrition 0.000 description 1
- 239000001728 capsicum frutescens Substances 0.000 description 1
- 230000023852 carbohydrate metabolic process Effects 0.000 description 1
- 235000021256 carbohydrate metabolism Nutrition 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 230000005779 cell damage Effects 0.000 description 1
- 208000037887 cell injury Diseases 0.000 description 1
- 210000000170 cell membrane Anatomy 0.000 description 1
- 235000005607 chanvre indien Nutrition 0.000 description 1
- BYCBJBLIOKGBPB-UHFFFAOYSA-N chiisanogenin Natural products O1C(=O)CC(O)C2(C)C(C(C)=C)CCC3(C)C4(C)CCC5(C(O)=O)CCC(C(=C)C)C5C4CC1C32 BYCBJBLIOKGBPB-UHFFFAOYSA-N 0.000 description 1
- 239000000460 chlorine Substances 0.000 description 1
- 229910052801 chlorine Inorganic materials 0.000 description 1
- 229910052804 chromium Inorganic materials 0.000 description 1
- 239000011651 chromium Substances 0.000 description 1
- 235000017803 cinnamon Nutrition 0.000 description 1
- SECPZKHBENQXJG-UHFFFAOYSA-N cis-palmitoleic acid Natural products CCCCCCC=CCCCCCCCC(O)=O SECPZKHBENQXJG-UHFFFAOYSA-N 0.000 description 1
- 229940043350 citral Drugs 0.000 description 1
- 235000020971 citrus fruits Nutrition 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 239000010941 cobalt Substances 0.000 description 1
- 229910017052 cobalt Inorganic materials 0.000 description 1
- GUTLYIVDDKVIGB-UHFFFAOYSA-N cobalt atom Chemical compound [Co] GUTLYIVDDKVIGB-UHFFFAOYSA-N 0.000 description 1
- 235000016213 coffee Nutrition 0.000 description 1
- 235000013353 coffee beverage Nutrition 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 229910052802 copper Inorganic materials 0.000 description 1
- 239000010949 copper Substances 0.000 description 1
- 235000019784 crude fat Nutrition 0.000 description 1
- KWGRBVOPPLSCSI-UHFFFAOYSA-N d-ephedrine Natural products CNC(C)C(O)C1=CC=CC=C1 KWGRBVOPPLSCSI-UHFFFAOYSA-N 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000000994 depressogenic effect Effects 0.000 description 1
- 238000001784 detoxification Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 235000013325 dietary fiber Nutrition 0.000 description 1
- 230000001079 digestive effect Effects 0.000 description 1
- 102000038379 digestive enzymes Human genes 0.000 description 1
- 108091007734 digestive enzymes Proteins 0.000 description 1
- 235000004879 dioscorea Nutrition 0.000 description 1
- ALVPFGSHPUPROW-UHFFFAOYSA-N dipropyl disulfide Chemical compound CCCSSCCC ALVPFGSHPUPROW-UHFFFAOYSA-N 0.000 description 1
- 208000016097 disease of metabolism Diseases 0.000 description 1
- 230000035619 diuresis Effects 0.000 description 1
- 239000002934 diuretic Substances 0.000 description 1
- 230000001882 diuretic effect Effects 0.000 description 1
- 235000011869 dried fruits Nutrition 0.000 description 1
- 230000035622 drinking Effects 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 208000000718 duodenal ulcer Diseases 0.000 description 1
- 230000004064 dysfunction Effects 0.000 description 1
- WEKCEGQSIIQPAQ-UHFFFAOYSA-N eleutheroside E2 Natural products COC1=C(O)C(OC)=CC(C2C3C(C(OC3)C=3C=C(OC)C(OC4C(C(O)C(O)C(CO)O4)O)=C(OC)C=3)CO2)=C1 WEKCEGQSIIQPAQ-UHFFFAOYSA-N 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 210000002257 embryonic structure Anatomy 0.000 description 1
- 229960002179 ephedrine Drugs 0.000 description 1
- PEYUIKBAABKQKQ-UHFFFAOYSA-N epiasarinin Natural products C1=C2OCOC2=CC(C2OCC3C2COC3C2=CC=C3OCOC3=C2)=C1 PEYUIKBAABKQKQ-UHFFFAOYSA-N 0.000 description 1
- IVTMALDHFAHOGL-UHFFFAOYSA-N eriodictyol 7-O-rutinoside Natural products OC1C(O)C(O)C(C)OC1OCC1C(O)C(O)C(O)C(OC=2C=C3C(C(C(O)=C(O3)C=3C=C(O)C(O)=CC=3)=O)=C(O)C=2)O1 IVTMALDHFAHOGL-UHFFFAOYSA-N 0.000 description 1
- 230000029142 excretion Effects 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 210000003754 fetus Anatomy 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 235000003599 food sweetener Nutrition 0.000 description 1
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 1
- WTEVQBCEXWBHNA-JXMROGBWSA-N geranial Chemical compound CC(C)=CCC\C(C)=C\C=O WTEVQBCEXWBHNA-JXMROGBWSA-N 0.000 description 1
- MASNOZXLGMXCHN-ZLPAWPGGSA-N glucagon Chemical compound C([C@@H](C(=O)N[C@H](C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(O)=O)C(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC=1NC=NC=1)[C@@H](C)O)[C@@H](C)O)C1=CC=CC=C1 MASNOZXLGMXCHN-ZLPAWPGGSA-N 0.000 description 1
- 229960004666 glucagon Drugs 0.000 description 1
- 235000013922 glutamic acid Nutrition 0.000 description 1
- 229960002989 glutamic acid Drugs 0.000 description 1
- 239000004220 glutamic acid Substances 0.000 description 1
- 229940096919 glycogen Drugs 0.000 description 1
- 238000000227 grinding Methods 0.000 description 1
- 230000012010 growth Effects 0.000 description 1
- 239000000122 growth hormone Substances 0.000 description 1
- 244000237330 gutta percha tree Species 0.000 description 1
- 229940093915 gynecological organic acid Drugs 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 239000011487 hemp Substances 0.000 description 1
- 230000002440 hepatic effect Effects 0.000 description 1
- 208000006454 hepatitis Diseases 0.000 description 1
- 231100000283 hepatitis Toxicity 0.000 description 1
- 235000008216 herbs Nutrition 0.000 description 1
- AKOJBFZCIRFXBA-UHFFFAOYSA-N hexa-1,3-diyne Chemical compound CCC#CC#C AKOJBFZCIRFXBA-UHFFFAOYSA-N 0.000 description 1
- CMJGAYUQSLJSCR-UHFFFAOYSA-N hibalactone Natural products C1=C2OCOC2=CC(C=C2C(CC=3C=C4OCOC4=CC=3)COC2=O)=C1 CMJGAYUQSLJSCR-UHFFFAOYSA-N 0.000 description 1
- 235000012907 honey Nutrition 0.000 description 1
- 230000003345 hyperglycaemic effect Effects 0.000 description 1
- 208000003532 hypothyroidism Diseases 0.000 description 1
- 230000002989 hypothyroidism Effects 0.000 description 1
- 230000001976 improved effect Effects 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 239000000492 insulin antagonist Substances 0.000 description 1
- 230000003914 insulin secretion Effects 0.000 description 1
- 230000000968 intestinal effect Effects 0.000 description 1
- 108010090785 inulinase Proteins 0.000 description 1
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 description 1
- 239000011630 iodine Substances 0.000 description 1
- 229910052740 iodine Inorganic materials 0.000 description 1
- 210000004153 islets of langerhan Anatomy 0.000 description 1
- DEXFQQWSJHKUIA-UHFFFAOYSA-N isochiisanoside Natural products OC1C(O)C(O)C(C)OC1OC1C(CO)OC(OCC2C(C(O)C(O)C(OC(=O)C34C(C(CC3)C(C)=C)C3C(C5(C)CCC6C(C)(C)OC(CC(O)=O)C6(C)C5C(O)C3)(C)CC4)O2)O)C(O)C1O DEXFQQWSJHKUIA-UHFFFAOYSA-N 0.000 description 1
- 230000007803 itching Effects 0.000 description 1
- 150000002576 ketones Chemical class 0.000 description 1
- 230000004140 ketosis Effects 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 230000003907 kidney function Effects 0.000 description 1
- SWHCKWOYUSDWOF-FYGCWZCISA-N koaburaside Natural products O(C)c1c(O)c(OC)cc(O[C@H]2[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O2)c1 SWHCKWOYUSDWOF-FYGCWZCISA-N 0.000 description 1
- SWHCKWOYUSDWOF-RGCYKPLRSA-N koaburaside Chemical compound COC1=C(O)C(OC)=CC(O[C@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)O)=C1 SWHCKWOYUSDWOF-RGCYKPLRSA-N 0.000 description 1
- 239000000252 konjac Substances 0.000 description 1
- 235000010485 konjac Nutrition 0.000 description 1
- 150000002596 lactones Chemical class 0.000 description 1
- 210000002429 large intestine Anatomy 0.000 description 1
- 239000003446 ligand Substances 0.000 description 1
- USOSNFWVEWONDB-UHFFFAOYSA-N liriodendrin Natural products COc1cc(cc(OC)c1OC2OC(CO)C(O)C(O)C2O)C3OC(C)(C)C4C(OC(C)(C)C34)c5cc(OC)c(OC6OC(CO)C(O)C(O)C6O)c(OC)c5 USOSNFWVEWONDB-UHFFFAOYSA-N 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 208000019423 liver disease Diseases 0.000 description 1
- 208000012866 low blood pressure Diseases 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 230000004199 lung function Effects 0.000 description 1
- 229960003646 lysine Drugs 0.000 description 1
- 235000018977 lysine Nutrition 0.000 description 1
- 239000011777 magnesium Substances 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- FYYHWMGAXLPEAU-IGMARMGPSA-N magnesium-24 Chemical compound [24Mg] FYYHWMGAXLPEAU-IGMARMGPSA-N 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- WPBNNNQJVZRUHP-UHFFFAOYSA-L manganese(2+);methyl n-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate;n-[2-(sulfidocarbothioylamino)ethyl]carbamodithioate Chemical compound [Mn+2].[S-]C(=S)NCCNC([S-])=S.COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC WPBNNNQJVZRUHP-UHFFFAOYSA-L 0.000 description 1
- 230000007721 medicinal effect Effects 0.000 description 1
- 230000003340 mental effect Effects 0.000 description 1
- 230000006371 metabolic abnormality Effects 0.000 description 1
- 208000030159 metabolic disease Diseases 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 210000003097 mucus Anatomy 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 229930014626 natural product Natural products 0.000 description 1
- 201000008383 nephritis Diseases 0.000 description 1
- 229910052759 nickel Inorganic materials 0.000 description 1
- 235000001968 nicotinic acid Nutrition 0.000 description 1
- 229960003512 nicotinic acid Drugs 0.000 description 1
- 239000011664 nicotinic acid Substances 0.000 description 1
- 235000013615 non-nutritive sweetener Nutrition 0.000 description 1
- 235000014571 nuts Nutrition 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 235000019198 oils Nutrition 0.000 description 1
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid group Chemical group C(CCCCCCC\C=C/CCCCCCCC)(=O)O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 1
- 239000003538 oral antidiabetic agent Substances 0.000 description 1
- 229940127209 oral hypoglycaemic agent Drugs 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 150000007524 organic acids Chemical group 0.000 description 1
- 235000005985 organic acids Nutrition 0.000 description 1
- 230000016087 ovulation Effects 0.000 description 1
- IPCSVZSSVZVIGE-UHFFFAOYSA-N palmitic acid group Chemical group C(CCCCCCCCCCCCCCC)(=O)O IPCSVZSSVZVIGE-UHFFFAOYSA-N 0.000 description 1
- 210000004738 parenchymal cell Anatomy 0.000 description 1
- 235000020232 peanut Nutrition 0.000 description 1
- 235000021017 pears Nutrition 0.000 description 1
- 208000033808 peripheral neuropathy Diseases 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 239000002831 pharmacologic agent Substances 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 230000035790 physiological processes and functions Effects 0.000 description 1
- 239000002574 poison Substances 0.000 description 1
- 230000007096 poisonous effect Effects 0.000 description 1
- 230000003449 preventive effect Effects 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 229960002429 proline Drugs 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000017854 proteolysis Effects 0.000 description 1
- 208000008128 pulmonary tuberculosis Diseases 0.000 description 1
- 235000020236 pumpkin seed Nutrition 0.000 description 1
- FDRQPMVGJOQVTL-UHFFFAOYSA-N quercetin rutinoside Natural products OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OC=2C(C3=C(O)C=C(O)C=C3OC=2C=2C=C(O)C(O)=CC=2)=O)O1 FDRQPMVGJOQVTL-UHFFFAOYSA-N 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 235000021067 refined food Nutrition 0.000 description 1
- 230000011514 reflex Effects 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 235000005493 rutin Nutrition 0.000 description 1
- IKGXIBQEEMLURG-BKUODXTLSA-N rutin Chemical compound O[C@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@@H]1OC[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](OC=2C(C3=C(O)C=C(O)C=C3OC=2C=2C=C(O)C(O)=CC=2)=O)O1 IKGXIBQEEMLURG-BKUODXTLSA-N 0.000 description 1
- ALABRVAAKCSLSC-UHFFFAOYSA-N rutin Natural products CC1OC(OCC2OC(O)C(O)C(O)C2O)C(O)C(O)C1OC3=C(Oc4cc(O)cc(O)c4C3=O)c5ccc(O)c(O)c5 ALABRVAAKCSLSC-UHFFFAOYSA-N 0.000 description 1
- 229960004555 rutoside Drugs 0.000 description 1
- 235000017509 safranal Nutrition 0.000 description 1
- 235000012045 salad Nutrition 0.000 description 1
- CMJGAYUQSLJSCR-ULIPXBITSA-N savinin Chemical compound C1=C2OCOC2=CC(\C=C2/[C@@H](CC=3C=C4OCOC4=CC=3)COC2=O)=C1 CMJGAYUQSLJSCR-ULIPXBITSA-N 0.000 description 1
- JGPMLTMSOKTANE-UHFFFAOYSA-N savinin Natural products O=C1OCC(/C/1=Cc2ccc3OCOc3c2)c4ccc5OCOc5c4 JGPMLTMSOKTANE-UHFFFAOYSA-N 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- VRMHCMWQHAXTOR-CMOCDZPBSA-N sesamin Natural products C1=C2OCOC2=CC([C@@H]2OC[C@@]3(C)[C@H](C=4C=C5OCOC5=CC=4)OC[C@]32C)=C1 VRMHCMWQHAXTOR-CMOCDZPBSA-N 0.000 description 1
- 230000036299 sexual function Effects 0.000 description 1
- 235000015500 sitosterol Nutrition 0.000 description 1
- NLQLSVXGSXCXFE-UHFFFAOYSA-N sitosterol Natural products CC=C(/CCC(C)C1CC2C3=CCC4C(C)C(O)CCC4(C)C3CCC2(C)C1)C(C)C NLQLSVXGSXCXFE-UHFFFAOYSA-N 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 235000014347 soups Nutrition 0.000 description 1
- 235000013555 soy sauce Nutrition 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 235000013599 spices Nutrition 0.000 description 1
- 150000003431 steroids Chemical class 0.000 description 1
- 150000003432 sterols Chemical class 0.000 description 1
- 235000003702 sterols Nutrition 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- ZSJLQEPLLKMAKR-GKHCUFPYSA-N streptozocin Chemical compound O=NN(C)C(=O)N[C@H]1[C@@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O ZSJLQEPLLKMAKR-GKHCUFPYSA-N 0.000 description 1
- 229960001052 streptozocin Drugs 0.000 description 1
- 230000035882 stress Effects 0.000 description 1
- 239000001384 succinic acid Substances 0.000 description 1
- 235000011044 succinic acid Nutrition 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 229960001734 sulfobromophthalein Drugs 0.000 description 1
- 235000020238 sunflower seed Nutrition 0.000 description 1
- 230000035900 sweating Effects 0.000 description 1
- 239000003765 sweetening agent Substances 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 229960003080 taurine Drugs 0.000 description 1
- 235000013616 tea Nutrition 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 230000035922 thirst Effects 0.000 description 1
- 210000001685 thyroid gland Anatomy 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 235000010384 tocopherol Nutrition 0.000 description 1
- 229930003799 tocopherol Natural products 0.000 description 1
- 229960001295 tocopherol Drugs 0.000 description 1
- 239000011732 tocopherol Substances 0.000 description 1
- 150000003626 triacylglycerols Chemical class 0.000 description 1
- 150000003648 triterpenes Chemical class 0.000 description 1
- 229960004441 tyrosine Drugs 0.000 description 1
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 description 1
- 235000002374 tyrosine Nutrition 0.000 description 1
- HFTAFOQKODTIJY-UHFFFAOYSA-N umbelliferone Natural products Cc1cc2C=CC(=O)Oc2cc1OCC=CC(C)(C)O HFTAFOQKODTIJY-UHFFFAOYSA-N 0.000 description 1
- ORHBXUUXSCNDEV-UHFFFAOYSA-N umbelliferone Chemical compound C1=CC(=O)OC2=CC(O)=CC=C21 ORHBXUUXSCNDEV-UHFFFAOYSA-N 0.000 description 1
- 210000004291 uterus Anatomy 0.000 description 1
- 229910052720 vanadium Inorganic materials 0.000 description 1
- GPPXJZIENCGNKB-UHFFFAOYSA-N vanadium Chemical compound [V]#[V] GPPXJZIENCGNKB-UHFFFAOYSA-N 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 230000017260 vegetative to reproductive phase transition of meristem Effects 0.000 description 1
- 208000016261 weight loss Diseases 0.000 description 1
- 230000004580 weight loss Effects 0.000 description 1
- 230000002087 whitening effect Effects 0.000 description 1
- 239000002023 wood Substances 0.000 description 1
- 230000037303 wrinkles Effects 0.000 description 1
- YEFOAORQXAOVJQ-UHFFFAOYSA-N wuweizischun A Natural products C1C(C)C(C)(O)CC2=CC(OC)=C(OC)C(OC)=C2C2=C1C=C(OC)C(OC)=C2OC YEFOAORQXAOVJQ-UHFFFAOYSA-N 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 description 1
- PSQYTAPXSHCGMF-BQYQJAHWSA-N β-ionone Chemical compound CC(=O)\C=C\C1=C(C)CCCC1(C)C PSQYTAPXSHCGMF-BQYQJAHWSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P10/00—Shaping or working of foodstuffs characterised by the products
- A23P10/20—Agglomerating; Granulating; Tabletting
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2200/00—Function of food ingredients
- A23V2200/30—Foods, ingredients or supplements having a functional effect on health
- A23V2200/328—Foods, ingredients or supplements having a functional effect on health having effect on glycaemic control and diabetes
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Botany (AREA)
- Mycology (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
본 발명은 곡물류와 종실류 및 1종이상의 생약재의 건조분말을 유효성분으로 하는 건강보조식품 조성물에 관한 것으로서, 좀더 상세하게는 곡물류와 종실류 및 특정 생약재의 건조분말을 유효성분으로 함유하며, 상기 조성물에 영양보조성분을 임의로 더욱첨가하여 된 당뇨병과 같은 각종 성인병의 예방 및 개선효과가 있는 건강보조식품 조성물에 관한 것이다. The present invention relates to a health supplement composition comprising a dry powder of cereals, seeds and one or more herbal medicines as an active ingredient, and more specifically, contains a dry powder of cereals, seeds and certain herbal medicines as an active ingredient. The present invention relates to a health supplement composition having the effect of preventing and improving various adult diseases, such as diabetes, by further adding a nutritional supplement to the composition.
본 발명의 함유되는 조성물은 곡물류와 종실류로서 현미, 쥐눈이콩, 양파를 함유하고 생약재로서 돼지감자, 구기자, 오미자, 율무, 복분자, 두충, 오가피, 산약, 인진쑥, 당귀, 황정, 함초 및 톳를 유효성분으로 하여 이루어진 조성물로 복용자에게 영양공급을 할 수 있을 뿐만 아니라, 종래 특정의약품에 의존한 당뇨병과 같은 각종성인병의 개선 및 예방 효과가 있을 뿐만 아니라 특정 약물에 대한 알러지와 같은 부작용을 일으키지 않고 혈당을 강하시키거나 혈압을 하강시키는 효과를 얻을 수 있다. Containing composition of the present invention contains brown rice, red eye bean, onion as grains and seeds and pig potato, wolfberry, Schisandra chinensis, Yulmu, Bokbunja, Tofu, Ogapi, medicinal herb, Injin mugwort, Angelica, Hwangjeong, Hamcho and 톳 A composition consisting of ingredients not only provides nutrition to the user, but also improves and prevents various adult diseases such as diabetes, which depend on conventional medicines, and prevents blood sugar without causing side effects such as allergy to certain drugs. The effect of lowering or lowering blood pressure can be obtained.
현미, 쥐눈이콩, 양파, 돼지감자, 구기자, 오미자, 율무, 복분자, 두충, 오가피, 산약, 인진쑥, 당귀, 황정, 함초, 톳, 당뇨병, 항지간효과, 항혈당효과, 혈압강하작용 Brown rice, Root bean, Onion, Pork potato, Gojijaja, Schisandra chinensis, Yulmu, Bokbunja, Tobacco, Ogapi, Powder, Injin mugwort, Angelica, Hwangjeong, Hamcho, 톳, Diabetes, Anti-hepatic effect, Antiglycemic effect, Blood pressure lowering effect
Description
본 발명은 건강보조식품에 관한 것으로서, 더욱 상세하게는 곡물류와 종실류 및 특정 생약재의 건조분말을 유효성분으로 하고, 상기 유효성분에 영양보조성분등을 임의로 더욱 첨가하여 함유하며, 분말 또는 환약(丸藥)의 형태로 형성되는 각종 성인병 및 성기능 개선의 효과를 가지는 건강보조식품 조성물에 관한 것이다. The present invention relates to a dietary supplement, and more particularly, to a dry powder of grains, seeds and specific herbal medicines as an active ingredient, and optionally further added nutritional supplements and the like to the active ingredient, powder or pills ( It relates to a health supplement composition having the effect of improving various adult diseases and sexual function formed in the form of iii).
최근 생활양식의 변화로 영양분의 과잉 섭취, 운동 부족에 의한 비만, 생활의 복잡화로 인한 스트레스, 또한 의학의 발달에 의해 고령화 사회로 접어들면서 주요 문제로 등장한 것 중의 하나가 당뇨병과 같은 성인병이다.In recent years, one of the major problems that has emerged as an aging society due to excessive consumption of nutrients, obesity due to lack of exercise, stress due to complications of life, and the development of medicine due to changes in lifestyle is adult diseases such as diabetes.
당뇨병은 탄수화물 대사에 이상이 생겨 혈중에 당이 많고(Hyperglycemia), 소변 속에 당이 많이 나오며(Glycosuria), 단백 분해가 증가되어(Ketosis 및 Acidosis) 나타나는 만성 대사성 질환이다. 이러한 탄수화물 대사 이상은 인슐린(Insulin)의 결핍; 글루카곤(Glucagon)양의 증가; 인슐린 길항 물질인 성장 호르몬, 아민류 또는 스테로이드류 등의 증가에 따라 나타난다.Diabetes is a chronic metabolic disease caused by abnormalities in carbohydrate metabolism, resulting in high blood sugar (Hyperglycemia), high sugar content in urine (Glycosuria), and increased proteolysis (Ketosis and Acidosis). Such carbohydrate metabolic abnormalities include deficiency of insulin; Increase in glucagon amount; It appears as an increase in insulin antagonists such as growth hormones, amines or steroids.
미국 당뇨병 통계 협회의 기준에 따르면, 1) 공복시 혈당이 140㎎/dl이상, 2) 포도당 75g을 경구 투여한 후 30분 간격으로 혈당을 측정하여, 2시간째 200㎎/dl 이상이고, 30분, 60분, 90분 중의 어느 하나가 200㎎/dl 이상인 경우, 3) 당불내성(糖不耐性, Glucose Intolerance)인 경우 당뇨병이라고 진단한다.According to the American Diabetes Statistics Association, 1) fasting blood glucose is 140 mg / dl or more, 2) 75 g of glucose is orally administered, and then blood glucose is measured at 30 minute intervals, at least 200 mg / dl for 2 hours, and 30 minutes , 60 minutes, 90 minutes if any one of more than 200mg / dl, 3) Glucose Intolerance is diagnosed as diabetes.
이 당뇨병은 매우 광범위하게 인체조직을 침해하는 질병으로서, 이는 만성피부질환(종기, 가려움증), 말초 신경장애(근육마비), 시력약화, 다뇨, 갈증, 과민성, 체중감소, 당뇨병성 케토산 혈증, 세포 기능장애(세포 손상), 망막 질환, 신경장애, 신장질환, 동맥 경화증 등의 합병증을 야기시킨다. 이러한 당뇨병은 오랫동안 자각증상 없이 진행되기 때문에 방치해 두는 일이 많은데, 그 결과 합병증이 진행되어 인체에 치명적인 손상을 일으키게 된다. 그러므로 가장 빠른 시기에 정상 혈당으로 환원시켜 주는 것이 필요하다.This diabetes is a very widespread disease of human tissue, including chronic skin diseases (boils and itching), peripheral nerve disorders (muscle paralysis), weakness of vision, polyuria, thirst, irritability, weight loss, diabetic ketoacidosis, It causes complications such as cell dysfunction (cell damage), retinal disease, neurological disorders, kidney disease and atherosclerosis. This diabetes is a long time without any symptoms, so it is left to neglect, as a result of the complications will cause fatal damage to the human body. Therefore, it is necessary to reduce the normal blood sugar at the earliest time.
따라서 이러한 당뇨병을 치료 및 예방하기 위해 각종 의약품, 천연식품 등이 이용되고 있다. 이중 의약품으로는 경구용 혈당강하제, 인슐린제, 합병증 치료제 등이 사용되고 있으나, 이는 저혈당증, 알레르기, 고지혈증, 다뇨증 등의 부작용이 수반되는 예가 많다.Therefore, various medicines, natural foods, etc. are used to treat and prevent the diabetes. Among these drugs, oral hypoglycemic agents, insulin agents, complications, etc. are used, but this is often accompanied by side effects such as hypoglycemia, allergies, hyperlipidemia and polyuria.
상기 의약품의 부작용을 개선하기 위하여 천연식품을 이용한 당뇨병 치료 및 예방을 위한 식품들이 각종 문헌과 특허공보에 제안되고 있다. 그 예로써, 일본특허공보 평 3-22134(1991. 3. 26)에서는 감귤류의 과실 껍질 분말 또는 추출물과 당근(Daucus carota L.)의 잎 또는 뿌리의 분말 또는 추출물과의 혼합물을 함유하는 혈당 개선 식품에 관하여 기재되어 있고, 일본특허공보 평 4-5652(1992. 2. 3) 에서는 백합과에 속하는 알로에류(알로에 아보레센스 밀러, 알로에 베라 등)의 수용성 성분에서 혈당 강하 작용을 갖는 것을 특징으로 하는 혈당개선식품에 관하여 기재되어 있고, 일본공개특허 공보 평 4-210576(1992. 7. 31) 에서는 견사 피브로인 유래의 평균 분자량 150~50,000의 수용성 단백질을 함유하는 것을 특징으로 하는 혈당상승억제식품 및 그 제조 방법에 관하여 기재하고 있으며, 일본공개특허공보 평 5-56749호(1993. 3. 9)에서는 곤약을 주성분으로 하여 커피, 녹차, 홍차 등의 추출액, 한천, 저칼로리 감미료 등을 첨가한 당뇨병 환자용 저칼로리 과자(열량 3㎉ 이하/100g당) 조성물 및 이의 제조방법에 관하여 기재되어 있다.In order to improve the side effects of the medicines, foods for treating and preventing diabetes using natural foods have been proposed in various documents and patent publications. As an example, Japanese Patent Application Laid-Open No. 3-22134 (March 26, 1991) improved blood sugar containing a mixture of fruit peel powder or extract of citrus fruits and powder or extract of leaf or root of carrot (Daucus carota L.). [0003] Japanese Patent Laid-Open No. 4-5652 (February 3, 1992) has a hypoglycemic action in water-soluble components of aloes belonging to the lily family (Aloe aboresense miller, aloe vera, etc.). Japanese Patent Laid-Open Publication No. Hei 4-210576 (July 31, 1992) discloses a glycemic-improvement food comprising a water-soluble protein having an average molecular weight of 150-50,000 derived from silk fibroin, and The preparation method is described. Japanese Unexamined Patent Application Publication No. Hei 5-56749 (March 9, 1993) has extracts of coffee, green tea, black tea and the like, agar and low calorie sweeteners based on konjac. A is one described with respect to low-calorie confectionery diabetic compositions and methods for their preparation (amount of heat than 3㎉ / 100g each) was added.
또한, 일본약학잡지[문헌명 : 일본 차(茶)의 혈당강하 성분에 관한 연구, 108권, 10호 964~970(1988)]에서는 당뇨병 유발제(스트렙토조토신)를 쥐에 투여하여 만든 고혈당쥐에 대한 녹차의 냉수(10℃ 이하)추출, 온수(40∼50℃)추출, 열수(90℃ 이상)추출한 엑기스의 혈당강하 작용을 조사한 결과, 녹차의 냉수추출 엑기스 성분이 약 40%의 혈당강하 작용을 나타내었으며, 이러한 혈당치를 감소시키는 유효성분인 분자량 4만 정도의 다당체 성분에 관하여 기재되어 있고, 일본생이학연구지[문헌명 : 말차(抹茶)의 당뇨병에 대한 실험적 연구, 1958년 12월 발행]에서는 말차(녹차)의 당뇨병에 대한 효과를 조사하기 위해 집토끼를 사용하여 말차 투여전과 투여후의 혈당치를 측정한 결과 11∼33% 범위의 혈당치 감소효과를 내는 등, 녹차(말차)의 당뇨병 억제효과에 관하여 기재되어 있으며, 프란그랜스 저널(Fragrance Journal)지[문헌명 : 차에 함유된 항당뇨병 성분, 1990년 11월호]에서는 일본경도대학 의학부에서 만성 당뇨병 증세가 있는 결핵환자 10명에 대한 말차복용에 따른 당뇨병 개선효과에 대한 임상 실험결과, 말차 음용시 뇨(尿)중의 당배설이 완전히 없어지거나, 뇨중 당이 줄어드는 등 말차(녹차)의 항당뇨 효과에 대한 임상실험 결과에 관하여 기재되어 있다.In addition, Japanese pharmacy magazine [Ref .: Study on the hypoglycemic component of Japanese tea, Vol. 108, No. 10, No. 964 ~ 970 (1988)], a hyperglycemic rat prepared by administering a diabetic agent (streptozotocin) to rats. The hypoglycemic activity of the extract of cold water (10 ℃ or less), hot water (40 ~ 50 ℃), and hot water (90 ℃ or more) extract of green tea was found to be about 40%. It is described as a polysaccharide component having a molecular weight of about 40,000, which is an effective ingredient for reducing blood sugar levels, and is published in the Japanese Journal of Biological Sciences [Experimental Study on Matcha Tea Diabetes, December 1958]. ] To investigate the effect of matcha (green tea) on diabetes mellitus, using green rabbits to measure blood glucose levels before and after the matcha tea, resulting in an effect of reducing glucose levels in the range of 11-33%. About The Fragrance Journal [Ref .: Anti-diabetic component of tea, November 1990 issue], says the Ministry of Medicine, University of Tokyo, Japan, for the use of matcha tea for 10 patients with chronic diabetes mellitus. Results of clinical trials on the improvement of diabetes mellitus, and the results of clinical trials on the anti-diabetic effect of matcha tea (green tea), such as the complete elimination of glucose excretion in urine when drinking green tea or reduced glucose in urine.
상기 인용특허공보 및 문헌에서 기재하고 있는 당뇨병 개선을 위한 천연물을 이용한 조성물들은 필수성분으로 함유하고 있는 곡물류 및 종실류를 특정 생약재와 함께 사용함으로써 당뇨병개선에 대한 상승효과를 제시하는 기술적 구성을 암시하거나 나타내고 있지 않다. Compositions using natural products for improving diabetes described in the cited patent publications and documents suggest a technical configuration that suggests a synergistic effect on diabetes improvement by using cereals and seeds containing essential ingredients together with certain herbal medicines. Not shown.
한편, 종래 선식이라는 이름으로 영양식, 이유식, 피부 미용식, 병후 회복식 등으로 이용되고 있는 곡물류 및 종실류로서 현미, 찹쌀, 율무, 보리, 흑콩, 팥, 교맥, 수수, 멸치, 다시마, 들깨, 흑깨, 마, 밤, 쑥, 호도, 잣, 땅콩, 해바라기씨, 호박씨, 호박, 시금치, 당근 등을 건조하여 분말형태로 사용하고 있으나, 이것은 단순 혼합된 형태로 환자 등에게 영양을 공급할 목적으로 이용되고 있는 것으로서 특정 질병에 대한 개선효과를 얻기위해서 이용된 예는 전무한 상태이다. On the other hand, grains and seeds used in nutrition, baby food, skin care, and recovery after illness are known as brown rice, glutinous rice, yulmu, barley, black beans, red beans, celery, sorghum, anchovies, kelp, perilla, black sesame. It is dried and used in powder form, but, chestnut, mugwort, wormwood, pine nut, peanut, sunflower seed, pumpkin seed, pumpkin, spinach, carrot, etc. There have been no examples of the use to improve the specific disease.
따라서, 본 발명에서는 당뇨병과 같은 성인병의 치료 및 예방에 있어서, 의약품에 의존한 단순한 치료나 예방보다는 이들 증후를 근본적으로 조장하는 제반 요인들을 해소하여 혈당을 조절하거나 혈압을 강하시키는 효과를 얻기위하여 곡물류 및 종실류에 특정 생약재들을 첨가하여 충분한 영양 공급 및 질병의 예방 또는 치료의 간접적인 효과를 얻을 수 있는 건강보조식품 조성물을 제공하는 것을 기술적 과제로 한다. Therefore, in the present invention, in the treatment and prevention of adult diseases such as diabetes, grains to obtain the effect of controlling blood sugar or lowering blood pressure by eliminating all factors that fundamentally promote these symptoms rather than simple treatment or prevention depending on medicines. And it is a technical problem to provide a dietary supplement composition that can be obtained by adding the specific herbal medicines to the seeds and sufficient nutritional supply and indirect effects of the prevention or treatment of diseases.
또한, 본 발명은 종래 의약품에 의존한 당뇨병 치료 및 예방에 있어서와 같은 약물 부작용을 일으키지 않고 당뇨병 개선, 즉 혈당의 강하 효과를 나타내는 건강보조식품 조성물을 제공하는 것을 목적으로 한다.
In addition, an object of the present invention is to provide a dietary supplement composition that exhibits a diabetic improvement, that is, a lowering effect of blood sugar, without causing drug side effects as in the treatment and prevention of diabetes depending on the conventional medicine.
상기한 목적을 달성한 본 발명에 의하면 곡물류와 종실류 및 1종이상의 생약재의 건조분말을 유효성분으로 하는 건강보조식품 조성물에 있어서, 곡물류와 종실류로서 현미 10~20%, 쥐눈이콩 10~20%, 양파 2~5%, 생약재로서 돼지감자 30~35%, 구기자 3~7%, 오미자 3~7%, 율무 3~7%, 복분자 3~7%, 두충 3~7%, 오가피 3~7%, 산약 2~5%, 인진쑥 2~5%, 당귀 4~7%, 황정 3~7%, 함초 2~5%, 톳 4~7%를 유효성분으로 하여 이루어진 것을 특징으로 하는 건강보조식품 조성물을 제공한다.According to the present invention to achieve the above object in the health supplement composition comprising a dry powder of cereals, seeds and at least one herbal medicine as an active ingredient, grains and seeds as brown rice 10-20%, rat eye 10-20 %, Onion 2 ~ 5%, medicinal herb 30 ~ 35%, wolfberry 3 ~ 7%, schizandra 3 ~ 7%, yulmu 3 ~ 7%, bokbunja 3 ~ 7%, tofu 3 ~ 7%, cucumber 3 ~ Health supplement, characterized by consisting of 7%, 2 ~ 5%, 2 ~ 5% of Injin mugwort, 4 ~ 7%, Angelica 3 ~ 7%, 2 ~ 5% seaweed, 4 ~ 7% Provide a food composition.
이하, 본 발명을 보다 상세히 설명하면 다음과 같다.Hereinafter, the present invention will be described in more detail.
본 발명의 조성물에 함유되는 곡물류인 현미(玄米, unpolished rice)는 공지의 방법으로 알파(α)화시켜 건조시킨 후 배전하여 제조하고, 분쇄기로 입도 30∼70메쉬로 분쇄하여 분말로 만든다. 이렇게 제조한 현미는 전체 조성물에 대하여 10∼20%의 양으로 함유하는 것이 바람직하다. 여기서 상기 현미는 현미 전체를 사용하기 보다는 현미의 배아부분만을 분리하여 사용하는 것이 더욱 좋으며, 상기 현미 대신에 거의 같은 성분을 함유하는 쌀알에 배아(胚芽, gemmule)가 50% 정도 남도록 도정한 한 쌀인 배아미를 사용하는 것이 더욱 좋다. Brown rice (unpolished rice), which is a grain contained in the composition of the present invention, is prepared by alpha-α, dried and roasted by a known method, and pulverized to a particle size of 30 to 70 mesh by a grinder to make a powder. The brown rice thus produced is preferably contained in an amount of 10 to 20% of the total composition. Here, the brown rice is better to use only the embryo part of the brown rice rather than using the whole brown rice, and instead of the brown rice is a rice in which the germ (胚芽, gemmule) in the rice grains containing almost the same ingredients remain Better to use embryos.
본 발명의 조성물에 함유되는 종실류로 사용되는 쥐눈이콩은 전체조성물에 있어서 10~20%의 양으로 함유하는 것이 바람직하며, 양파는 전체 조성물에 있어서 2~5%의 양으로 함유하는 것이 바람직하다. 상기 종실류는 공지의 방법으로 쪄서 자연 건조 또는 건조기에서 건조시킨 후 배전하여 제조하고, 분쇄기로 입도 30∼70메쉬로 분쇄하여 분말로 만들어 사용한다. The mouse eye bean used as the seed species contained in the composition of the present invention is preferably contained in an amount of 10 to 20% in the total composition, and the onion is preferably contained in an amount of 2 to 5% in the total composition. . The seeds are steamed by a known method, dried in a dryer or dried in a drier, and then roasted. The seeds are pulverized to a particle size of 30 to 70 mesh and used to make a powder.
본 발명의 조성물에 사용되는 생약재로는 돼지감자, 구기자, 오미자, 율무, 복분자, 두충, 오가피, 산약, 인진쑥, 당귀, 황정, 함초, 톳 등이 사용되며, 이들은 주로 혈당강하작용 및 혈압하강작용을 하는 성분을 다량 함유하고 있다. The herbal medicines used in the composition of the present invention are pig potato, gojijaja, Schisandra chinensis, Yulmu, Bokbunja, Tochung, Ogapi, powder, Injin mugwort, Angelica, yellow sugar, hamcho, 톳 and the like, these are mainly hypoglycemic action and blood pressure lowering action It contains a large amount of ingredients.
상기한 생약재들은 공지의 방법으로 상온에서 자연 건조시키거나 건조기를 이용하여 건조시킨 후 배전하여 제조하고, 분쇄기로 입도30~70메쉬로 분쇄하여 분말로 만들어 사용한다.The herbal medicines are naturally dried at room temperature by a known method or dried using a dryer and then roasted, and then used to make powder by grinding to a particle size of 30 to 70 mesh.
상기한 생약재들의 함량은 본 발명의 전체 조성물에 대하여 돼지감자는 30~35%의 양으로 함유하는 것이 바람직하고, 구기자는 3~7%의 양으로 함유하는 것이 바람직하고, 오미자는 3~7%의 양으로 함유하는 것이 바람직하고, 율무는 3~7%의 양으로 함유하는 것이 바람직하고, 복분자는 3~7%의 양으로 함유하는 것이 바람직하고, 두충은 3~7%의 양으로 함유하는 것이 바람직하고, 오가피는 3~7%의 양으로 함유하는 것이 바람직하고, 산약은 2~5%의 양으로 함유하는 것이 바람직하고, 인진쑥은 2~5%의 양으로 함유하는 것이 바람직하고, 당귀는 4~7%의 양으로 함유하는 것이 바람직하고, 황정은 3~7%의 양으로 함유하는 것이 바람직하고, 함초는 2~5%의 양으로 함유하는 것이 바람직하고, 톳은 4~7%의 양으로 함유하는 것이 바람직하다. 만일, 이들 생약재가 상기 함유량에 있어서 최저량 미만으로 함유될 경우에는 당뇨병의 개선효과 또는 혈압강하 효과가 미미하고, 최고량을 초과하여 함유될 경우에는 생약 특유의 맛과 향이 강하게 되어 맛에 거부감을 느끼게 되는 단점이 있다. The content of the herbal medicines is preferably contained in the amount of 30 ~ 35% of pork potato, the amount of wolfberry in the amount of 3 to 7%, and Schisandra chinensis 3 to 7% with respect to the total composition of the present invention It is preferable to contain it in the quantity of, and it is preferable to contain it in the quantity of 3-7%, It is preferable to contain bokbunja in the quantity of 3-7%, and to contain the worms in the quantity of 3-7% It is preferable to contain cinnamon in an amount of 3 to 7%, it is preferable to contain an acidic acid in an amount of 2 to 5%, and to contain phosphorus mugwort in an amount of 2 to 5%. Is preferably contained in an amount of 4-7%, it is preferable to contain cyanide in an amount of 3-7%, it is preferable to contain a seaweed in an amount of 2-5%, and 톳 is 4-7% It is preferable to contain in an amount. If these herbal medicines are contained in the amount below the minimum, the effect of diabetic improvement or blood pressure lowering is insignificant. If the herbal medicines are contained in the amount exceeding the maximum amount, the taste and aroma unique to the herbal medicine become strong and the taste is rejected. There is a drawback to this.
상기한 본 발명의 조성물에 영양보조성분으로 호박, 다시마, 연자육, 통밀, 소맥배아, 효모, 효모엑기스 건조분말, 호도, 비타민 A, 비타민 B1, B2, B5, B6, B12, 비타민 C, 비타민 D, 비타민 E, 비타민 F, 필수불포화지방산, 필수 아미노산, 해조분말, 마늘분말, 글루코만난, 부추건조분말, 양엉겅퀴, 탈지분유, 전지분유, 올리고당, 과당 및 구연산으로 이루어진 군에서 선택된 적어도 하나의 건조분말을 전체조성물 대비 적정량을 중량비로 첨가할 수 있다. As a nutritional supplement to the composition of the present invention, pumpkin, kelp, lotus root, whole wheat, wheat germ, yeast, yeast extract dry powder, hoedo, vitamin A, vitamin B1, B2, B5, B6, B12, vitamin C, vitamin D At least one dry powder selected from the group consisting of vitamin E, vitamin F, essential unsaturated fatty acids, essential amino acids, seaweed powder, garlic powder, glucomannan, leek dried powder, thistle, skim milk powder, whole milk powder, oligosaccharide, fructose and citric acid It may be added in an appropriate ratio by weight relative to the total composition.
상기와 같은 비율로 조성된 본 발명의 조성물은 건조분말을 혼합하여 분말상태로 이용할 수 있고, 공지의 방법으로 상기 조성물을 복용이 용이하고, 이동과 저장이 간편하며, 복용시 체내에서 흡수가 완만하게 하도록 하기 위하여 가루로만들어 혼합하여 된 본 발명의 조성물에 꿀 또는 풀 등의 부형제를 첨가하여 환약(丸藥)의 형태로 빚어서 제조하여 이용한다. The composition of the present invention prepared in the above ratio can be used in a powder state by mixing dry powder, it is easy to take the composition by a known method, easy to move and store, the absorption is slow in the body when taking In order to make it so that the composition of the present invention is made of powder and mixed with an excipient such as honey or paste to form in the form of pills (丸藥) to prepare and use.
이하, 본 발명의 조성물에 사용되는 곡물류, 종실류 및 생약재들을 종래의 문헌에 공지되어 있는 자료를 바탕으로 각각의 조성물의 주요성분 및 효능 · 효과를 설명하면 다음과 같다. Hereinafter, the main ingredients, efficacy and effects of each composition based on the data known in the prior art grains, seeds and herbs used in the composition of the present invention.
1. 현미(玄米, unpolished rice)1. Unpolished rice
현미의 구조는 바깥쪽부터 과피(果皮)·종피(種皮)·호분층(糊粉層) 등의 쌀겨 층과 쌀알의 기부(基部)의 작은 부분을 차지하고 있는 배(胚)와, 나머지의 대부분을 차지하는 배젖으로 이루어졌다. 이 배젖은 주로 녹말 입자로 차 있고, 백미로서 식용으로 하는 부분이다. 이상 각 부분의 현미 전립에 대한 중량비는 쌀겨층 5∼6%, 배 2∼3%, 배젖 92%의 비율로 되었다. The structure of brown rice consists of a layer of rice bran such as rinds of skin, seed skin and whistle layer, the pear which occupies a small part of the base of rice grain, and most of the rest from the outside. Made up of occupied breast milk. This belly milk is mainly filled with starch particles and is a part which is eaten as white rice. The weight ratio with respect to the brown rice whole of each part was made into the ratio of 5 to 6% of rice bran layers, 2 to 3% of pears, and 92% of breast milk.
현미의 표준적 화학조성은 수분 15.5%, 단백질 7.4%, 지질(脂質) 3.0%, 당질 71.8%, 섬유 1.0%, 회분 1.3%, 비타민 B1은 100g 중 0.54mg으로 당질(녹말)이 대부분을 차지하고, 단백질이나 지방은 많지 않다. 비타민 B1은 많다. 또 현미는 정백으로 인한 영양분의 손실이 없으므로 백미에 비하여 지방, 단백질, 비타민 B1, B2가 풍부하다. 또 가공으로 인한 양의 감소도 없다. Standard chemical composition of the brown rice was 15.5% moisture, 7.4% protein, lipids (脂質) 3.0%, carbohydrates 71.8%, fiber 1.0%, ash 1.3%, vitamin B 1 is the most carbohydrate (starch) and 0.54mg of 100g Occupy, not much protein or fat. Vitamin B 1 is high. In addition, brown rice is rich in fat, protein, vitamin B 1 and B 2 compared to white rice because there is no loss of nutrients due to whitening. There is also no reduction in the amount due to processing.
2. 쥐눈이콩2. Rat Bean
한자어로 서목태(鼠目太)라고도 하며, 학명은 여두(Rhynchosia Nulubilis)라 한다. 옛날부터 콩 가운데서 약성이 높아 약재로 사용되어져 왔기 때문에 약콩이라 불리 우며, 그 성질이 따뜻하고 맛은 달며 독이 없다.It is also called Seomoktae (鼠目 太) in Chinese. The scientific name is Rhynchosia Nulubilis. It is called medicinal soybean because it has been used as a medicinal herb because of its high medicinal properties since ancient times. It is warm in nature, tastes sweet and has no poison.
이 쥐눈이콩의 주 성분은 단백질, 지방, 섬유, 회분, 펜토산, 당분 등이 함유되어 있으며, 일반 식용 콩에 비해 그 함유량이 월등히 많은 것으로 알려져 있다. 특히 쥐눈이콩은 그 어떤 콩보다도 약성이 강하여 해독성이 탁월하고 감로정이 많아 소염, 재생기능이 으뜸이고 섬유질이 많아 장의 활성에 기여하여 모든 병을 예방해 주고 인체의 조직을 빠르게 회복시켜주는 효과가 탁월하다. The main component of this rat bean contains protein, fat, fiber, ash, pentosan, sugar, etc., and it is known that its content is much higher than that of general beans. In particular, rat eye is stronger than any other soybean, so it is excellent in detoxification and nectar. It is excellent in anti-inflammatory and regenerative function, and it has a lot of fiber, which contributes to the activity of the intestine. .
상기 쥐눈이콩의 한방기록을 살펴보면 다음과 같다.Looking at the herbal record of the rat eye is as follows.
본초강목에서는 서목태는 복창을 내리고 위열을 없애며 마비증을 다스리고 어혈을 풀어버리며, 기를 늘리고 심신의 피로와 쇠약을 예방하고 정력을 기르며, 신장병을 다스리며 기를 내리어 모든 풍열을 억제하고 혈액을 활발히 하며 모든 독을 푼다라고 기록되어 있다. In herbaceous wood, Seomoktae lowers the abdominal cavity, eliminates stomach fever, controls paralysis, releases blood, improves energy, prevents physical and physical fatigue and weakness, cultivates energy, controls kidney disease, suppresses all fever, activates blood, It is said to be poisonous.
또한, 그 어떤 콩보다도 약성이 강하여 현대인들의 성인병 등의 치료에 효과적이며, 특히 풍부하게 들어있는 지방질은 혈액속에서 콜레스테롤치가 높아지는 것을 막고 동맥혈관의 벽에 달라붙은 콜레스테롤을 녹여내는 작용을 함으로서 당뇨병의 예방 및 치료효과도 지니고 있으며, 혈압강하효과도 있다. In addition, it is more vulnerable to soybeans than any other soybean, and is effective in treating adult diseases such as modern people. Especially rich in fat prevents cholesterol from rising in the blood and dissolves cholesterol attached to the walls of arterial vessels. It also has a preventive and therapeutic effect, and also has a blood pressure lowering effect.
또한, 감로정이 많아 소염, 재생기능이 으뜸이고 섬유질이 많아 장의 활성에 기여한다. In addition, there is a lot of sweetener, anti-inflammatory, regenerative function is the chief and a lot of fiber contribute to the activity of the intestine.
상기와 같은 효과를 지닌 쥐눈이콩의 장점은 생식은 물론 가공약재로 사용되고, 콩 비린내가 거의 없고 고소한 맛이 강하며, 약리적 성분이 콩 가운데서 최고로 평가되어 있다. 또한, 생김새가 독특하여 일반 검정콩과 구분이 쉽게 되고, 약콩강정/약콩된장, 간장, 고추장 등 가공식품의 종류가 다양하다.The merits of rat eye with the above effects are used as raw foods as well as processed medicines, soybeans have little fishy smell, strong taste, and pharmacological ingredients are evaluated as the best among soybeans. In addition, its unique appearance makes it easy to distinguish it from ordinary black soybeans, and there are various types of processed foods such as weak soybean / jeong soybean paste, soy sauce and red pepper paste.
3. 양파(onion, Allium cepa)3. onion (Allium cepa)
외떡잎식물 백합목 백합과의 두해살이풀로서, 비늘줄기는 품종에 따라 다소 차이가 있으나 납작한 둥근 모양 또는 둥근 모양이며 겉에 얇은 막질(膜質:얇은 종이처럼 반투명한 것)의 자줏빛이 도는 갈색 껍질이 있고 안쪽의 비늘은 두꺼우며 층층이 겹쳐지고 매운 맛이 난다. 잎은 속이 빈 원기둥 모양이고 짙은 녹색이며 꽃이 필 때 마르고 밑 부분이 두꺼운 비늘조각으로 되어 있다. It is a biennial plant of the monocotyledonous lily of the genus Liliumaceae. The scaly stem is somewhat different depending on the variety, but has a flat round shape or a round shape, and has a thin filmy purplish brown shell on the outside. The inner scales are thick, layered, and taste spicy. The leaves are hollow cylinders, dark green, dry when blossoming, and have thick scaly bases.
양파는 주로 비늘줄기를 식용으로 하는데, 비늘줄기에서 나는 독특한 냄새는 이황화프로필·황화알릴 등의 화합물 때문이다. 이것은 생리적으로 소화액 분비를 촉진하고 흥분, 발한, 이뇨 등의 효과가 있다. Onions are mainly edible, and the peculiar smell of scales is due to compounds such as propyl disulfide and allyl sulfide. This physiologically promotes the secretion of digestive juices and has the effect of excitement, sweating and diuresis.
또한 비늘줄기에는 각종 비타민과 함께 칼슘·인산 등의 무기질이 들어 있어 혈액 중의 유해 물질을 제거하는 작용이 있다. 비늘줄기는 샐러드나 수프, 그리고 고기 요리에 많이 사용되며 각종 요리에 향신료 등으로 이용된다. 잎은 100g 중에 비타민A 5,000 IU, 비타민C 45mg, 칼슘 80mg, 마그네슘 24mg, 칼륨 220mg이 들어 있다. In addition, the scales contain minerals such as calcium and phosphate together with various vitamins to remove harmful substances in the blood. Scales are often used in salads, soups, and meat dishes, and are used as spices in various dishes. The leaves contain vitamin I 5,000 IU, vitamin C 45 mg, calcium 80 mg, magnesium 24 mg and potassium 220 mg in 100 g.
4. 돼지감자(Helianthus tuberosus, 생약명은 '국우'라 함)4. Pork Potato (Helianthus tuberosus)
뚱딴지라고도 하며, 쌍떡잎 식물 초롱꽃목 국화과의 여러해살이풀로서 땅속줄기의 끝부분이 굵어져서 덩이줄기를 형성하는데, 이 덩이줄기 부분을 돼지감자(Helianthus tuberosus, 생약명은 '국우'라 함)라고 한다. 성(性)은 양(凉)하고 맛은 쓰다. 함유성분은 이눌린(Inulin), 회분(灰分)이 주를 이루고 있고, 상기 이눌린(Inulin)은 약 15%이상 함유되어 있으며 천연인슐린이라고도 불리운다. 이 이눌린은 주로 국화과 식물(돼지감자의 덩이줄기, 달리아의 덩이뿌리, 엉겅퀴의 뿌리 등)에 콜로이드상으로 존재하는 저장다당류의 일종으로서, 이눌린의 구조는 프룩토오스(과당)가 β-1, 2- 결합으로 20∼40개 중합하고, 프룩토오스사슬의 환원말단에 1개의 글루코오스가 수크로오스와 마찬가지로 α-1, 1- 결합으로 이어져 있는데 분자량은 약 5000이다. 산과 함께 가열하거나 이눌라아제라는 효소와 작용시키면 가수분해되어 전부 프룩토오스가 된다. 예를 들어 pH1에서 온도를 37℃로 할 경우 수시간 내에 80% 정도 분해되어 D-프룩토오스와 적은 양의 당류를 생성하지만 pH3에서는 거의 분해되지 않는다. 이눌린은 인체에 무해하며, 생체에 투여하면 혈관벽을 자유롭게 통과하고 세포외액 속으로 확산되지만 세포막은 통과하지 못하기 때문에 세포외액량을 측정하는 데 적합한 물질이다. 또한 신장 사구체(絲球體)의 여과능력을 시험할 때에도 이용된다. It is also called a fat place, a perennial herb of the dicotyledonous plant Campanula Asteraceae. The end of the underground stem is thickened to form tubers. This tuber part is called Pork Potato (Helianthus tuberosus). Sex is positive and taste is bitter. The main ingredient is inulin, and ash is mainly used. The inulin is contained in about 15% or more and is also called natural insulin. This inulin is a type of colloidal polysaccharide that mainly exists in asteraceae plants (tubes of pork potatoes, tubers of dahlias, roots of thistles, etc.), and the structure of inulin is fructose (fructose) β-1, 20 to 40 polymerized by two-bond, one glucose at the reducing end of the fructose chain is connected to the α-1, 1-link as in the case of sucrose, the molecular weight is about 5000. When heated with an acid or interacted with an enzyme called inulinase, it is hydrolyzed to form fructose. For example, when the temperature is set at 37 ° C. at pH 1, it decomposes about 80% within a few hours to produce D-fructose and a small amount of sugar, but little at pH 3. Inulin is harmless to the human body and is suitable for measuring the amount of extracellular fluid when administered to a living body because it freely passes through the blood vessel wall and diffuses into the extracellular fluid but does not pass through the cell membrane. It is also used to test the filtration capacity of kidney glomeruli.
상기 이눌린은 생체 내 소화 효소에 의해 분해되지 않고 분해되더라도 프락토스 형태이므로 혈당 상승과는 관련 없이 반대로 혈당치를 떨어뜨리는 효과가 있다. The inulin is fructose form, even if it is not degraded by digestive enzymes in vivo, and thus has an effect of lowering blood sugar levels irrespective of blood sugar rise.
5. 구기자(枸杞子, Lycii Fruictus)5. Lycii Fruictus
구기자나무(Lycium chinense)의 성숙된 열매로서 한쪽이 뾰족한 방추형의 적색을 한 과실이다. A mature fruit of the Lycium chinense , which has a pointed spindle-shaped red fruit on one side.
이약의 주성분은 단백질, 지방, 당질, 칼슘, 인, 철분, 베타인, 루틴, 비타민(A, B1, B2, C), 각종 아미노산 등이 함유되어 있어 흡수가 빠르다. The main ingredient of this drug is protein, fat, carbohydrate, calcium, phosphorus, iron, betaine, rutin, vitamins (A, B1, B2, C), various amino acids, etc. It contains a quick absorption.
이 약은 아미노산 성분중 베타인(betaine) 대사물에 의해 주도되는 항지간효과와 혈압하강효과, 항혈당효과와 혈압하강효과가 있어 자양·강장제, 해열제로 쓰고 간기능 보호 작용이 뛰어나 부작용이 별로 없다. 또한, 이 약은 시력을 좋게 하고 당뇨병 등의 성인병을 예방하며 폐와 신장의 기능을 좋게 하는 효과가 있다. This drug has anti-interstitial effect, blood pressure lowering effect, anti-glycemic effect and blood pressure lowering effect led by betaine metabolite among amino acids, and it is used as nourishment, tonic and antipyretic, and has excellent side effect of protecting liver function. none. In addition, the drug improves vision and prevents adult diseases such as diabetes and improves lung and kidney function.
6. 오미자(五味子, Schizandrae fructus)6. Schizandrae fructus
오미자(Schizandrae chinensis)의 열매를 말린 것으로 지름 5-10㎜내외의 적색~적자~흑자색의 한 과실로서 겉면은 건조에 따라 균일하지가 않으며 그물모양의 주름이 있고 이 주름에 때로는 흰색의 분상이 붙어 있는 경우가 있고, 독특한 향취(香臭)가 있어 식별이 용이하고 맛은 처음엔 시고 나중에는 쓰고 떫다.Dried fruits of Schizandrae chinensis , 5 ~ 10 mm in diameter, red to red to black purple fruit, the outer surface of which is not uniform with drying, there are net-like wrinkles and sometimes white powder There is a case, and it has a unique scent, so it is easy to identify, and the taste is sour at first and later used.
이약의 주성분은 시트랄(citral)을 주성분으로 하는 정유 2%, 리간스(Ligans)로 스키잔드린(Schiandrin), 데옥시스키잔드린(deoxyschiandrin), γ-스키잔드린(γ-Schiandrin), 고미신(gomisin)류 등이 함유되어 있고, 지방유부분으로 스테롤(sterol), 토코페롤(tocopherol), 왁스(wax) 0.5%, 올레익(oleic), 리놀레익(Linoleic), 스테아릭(stearic), 팔미틱(palmitic), 마이리스틱(myristic), 팔리톨레익 엑시드(palmitoleic acid)등이 함유되어 있으며, 식물산으로 시트릭산(citric acid), 말릭산(malic acid), 아스코빅산(ascorbic acid), 석시닉산(succinic acid) 등이 함유되어 있다. The main components of this drug are citral (essential oil) 2%, Ligans (Siganandrin), deoxyschiandrin (γ-Schiandrin), Gomisin, etc. are included, and the fatty oil is sterol, tocopherol, wax 0.5%, oleic, linoleic, stearic, Contains palmitic, mystic, and palmitoleic acid, which are citric acid, malic acid, ascorbic acid, Succinic acid and the like.
이 약의 약리효과는 중추(호흡, 순환운동)에 작용하여 반사기능을 항진시키며, 해소중추에 대해서도 억제작용이 있어 진해효과를 지닌다. 또한, 분만기의 자궁에 작용하여 그 생리기능을 항진시키는 효과가 있으며, 상기 함유성분중 스키잔드린(Schiandrin), 고미신(gomisin)등은 스트레스성 궤양을 억제하는 효과가 있으며, CCI, 갈락토스아민(galactosamine)에 의해 유발되는 동물의 s-GPT, s-GOT의 병적 상승을 억제하여 간기능을 강화하는 효과가 있고, 수침제제는 정신노동에 의한 과로에 강장적인 효과를 나타낸다. 또한, 종자유분획은 박테리오시달 활성(bacteriocidal action)을 갖고 있어 항균작용의 효과가 있다.The drug's pharmacological effect acts on the central (breathing, circulatory movements) and promotes reflexes. It also has an inhibitory effect on the relieving center. In addition, it acts on the uterus of the labor period and has the effect of promoting its physiological function, and the skidrin (Schiandrin), gomisin (such as) among the components have the effect of suppressing stress ulcers, CCI, galactosamine (galactosamine) inhibits the pathological elevation of s- GPT and s- GOT in animals and enhances liver function, while acupuncture agents have a tonic effect on overwork due to mental labor. In addition, the seed oil fraction has a bacteriocidal action and thus has an antimicrobial effect.
7. 율무(Coix lachryma-jobi. mayuen)7. Cox lachryma-jobi. Mayuen
율무의 종피를 제거한 종자를 의이인(薏苡仁, Coicis Semen)이라 하며, 이 의이인을 약재로 사용한다. 이 약의 주 성분은 전분(澱粉) 51%, 조단백질(粗蛋白質)17.6%, 지방유, 시토스테롤(sitosterol), 스티그마스테롤(stigmasterol), β-시토스테롤(β-sitosterol), 코익세놀라이드(coixenolide), 코익솔(coixol)등을 함유하며, 글루칸(Glucans)으로 코익산 A, B, C(coixan A, B, C), 엑시딕 헤테로글루칸(acidic heteroglucan) 등을 함유하며 기타 벤조옥사지논(benzoxazinon), 트란스-페루로일 스티그마스탄올(trans-feruloyl stigmastanol) 등이 함유되어 있다. Seeds removed from the bark of Yulmu are called Euiin (薏苡仁, Coicis Semen), which is used as a medicine. Its main components are 51% starch, crude protein 17.6%, fatty oils, sitosterol, stigmasterol, β-sitosterol, and coixenolide. , Coixol, etc., Glucans (colucan A, B, C), acidic heteroglucan (acidic heteroglucan), etc., and other benzoxazinon ), trans- may contain such stigmasterol Stan ol (trans -feruloyl stigmastanol) one in Peru.
이 약의 약리효과는 상기 성분중 코익산 A, B, C(coixan A, B, C)는 혈당강하효과가 있고, 트란스-페루로일 스티그마스탄올(trans-feruloyl stigmastanol)등은 배란유발작용(排卵誘發作用)의 효과가 있다. 또한, 상기 성분중 엑시딕 헤테로글루칸(acidic heteroglucan)은 항보체 활성(抗補體 活性)의 효과가 있다. The pharmacological effect of this drug is that coic acid A, B, C (coixan A, B, C) has a hypoglycemic effect, and trans- feruloyl stigmastanol has an ovulation-inducing effect. (排卵 誘發 作用) is effective. In addition, the acidic heteroglucan (acidic heteroglucan) of the component has the effect of anti-complement activity (抗 補 體 活性).
기타 상기 성분중 코익세놀라이드(coixenolide)는 항종양성(抗腫瘍性)이 있으며, 의이인가루 반죽(Coicis Semen Paste)의 도포(塗布)에 의해 이상각질증식(異常角質增殖)에 의한 사마귀를 제거시키는 효과가 있다. Among the other ingredients, coixenolide has antitumor properties and removes warts due to abnormal keratinous growth by coating Coicis Semen Paste. It is effective to let.
8. 복분자(覆盆子, Rubus Fructus)8. Bokbunja (覆盆子, Rubus Fructus)
복분자딸기(Rubus coreanum)의 채 익지않은 열매로서 그 성상은 작은 단과(單果)가 여러개 모여서 덩어리를 이룬 것으로 원추형~편압된 구형을 이루로 있다. It is a raw fruit of Rubus coreanum , and its constellation is a condensed to depressed sphere.
이 약의 주 성분은 유기산(Organic acids)으로 말릭산(malic acid), 시트릭산(citric acid), 타르타릭산(tartaric acid)등을 함유하고, 당(糖, Sugars)으로는 프룩토스(fructose), 글루코스(glucose)등이 함유되어 있으며, 비타민(Vitamins)으로는 비타민 C, 비타민 A류 등이 함유되어 있으며, 트리테르페노이드(Triterpenoids)로서 니가이키고사이드(nigaichigoside) F1, F2,(1.2), 코레아노사이드(coreanoside) F1, 코레아노게닉 엑시드(coreanogenic acid)등이 함유되어 있다. Its main ingredient is organic acids containing malic acid, citric acid and tartaric acid, and sugars are fructose ), Glucose, etc., and vitamins (Vitamins) contain vitamin C, vitamin A, etc., and triterpenoids (nigaichigoside) F1, F2, ( 1.2), coreanoside F1, coreanoogenic acid, and the like.
이 약은 항균작용의 효과가 있고, 약성이 감(甘), 산(酸)이어서 수렴효과가 있다. This drug has the effect of antibacterial action, weakness (감), acid (酸) is a convergent effect.
9. 두충(杜仲, Eucommia cortex)9. Eucommia cortex
이 약은 두충나무(Eucommia ulmoides)의 수피를 약용으로 사용하는 것으로, 그 성상은 두께 0.3~0.7㎝인 판상이다. This drug uses the bark of Eucommia ulmoides for medicinal purposes, and its shape is 0.3 ~ 0.7㎝ thick.
이 약의 주 성분은 리간스(Ligans)와 이리노이드(Iridois)이다. 상기 리간스(Ligans)로는 (+)-피노레시놀-디-β-D-글루코사이드( (+)-pinoresinol-di-β-D-glucoside), (+)-메디오레시놀-디-O-β-D-글루코피라노사이드((+)-medioresionol-di-O-β-D-glucopyranoside), 리리오덴드린(liriodendrin), (-)-올리빌4`,4"-디-O-β-D-글루코피라노사이드((-)-olivil4`,4"-di-O-β-D-glucopyranoside), 코아부라사이드(koaburaside), 제니피오사이드(genipioside), 제니피오사이딕 엑시드(genipiosidic acid) 등이 함유되어 있고, 상기 이리노이드(Iridois)로는 울모사이드(ulmoside)가 함유되어 있다. 이 외에도 다량의 알칼로이드가 함유되어 있다. The main components of this drug are Ligans and Iridois. Ligans include (+)-pinoresinol-di-β-D-glucoside ((+)-pinoresinol-di-β-D-glucoside) and (+)-medioresinol-di-O -(beta) -D-glucopyranoside ((+)-medioresionol-di-O-β-D-glucopyranoside), liriodendrin, (-)-olibil4`, 4 "-di-O -(beta) -D-glucopyranoside ((-)-olivil4`, 4 "-di-O-β-D-glucopyranoside, koaburaside, genipioside, geniophysidic acid (genipiosidic acid) and the like, and the irinoid (Iridois) contains the ulmoside (ulmoside). In addition, it contains a large amount of alkaloids.
상기 주성분중 리간스인 (+)-피노레시놀-디-β-D-글루코사이드((+)-pinoresinol-di-β-D-glucoside)가 이 약의 주체물질로서 혈압강하작용을 하며, 대단히 지효성이다. 이외의 다른 리그난(lignan)도 효과가 있으며, 기타 토니파이효과(tonify effect)도 있다. Ligands (+)-pinoresinol-di-β-D-glucoside ((+)-pinoresinol-di-β-D-glucoside), which is the main ingredient, acts as a main substance of this drug and acts to lower blood pressure. Ji Hyosung. Other lignans also work, and there are other toify effects.
10. 오가피(五加皮, Acanthopanacis Cortex)10. Acanthopanacis Cortex
오갈피나무(Acanthopanax sessiliflorum) 및 동속식물의 뿌리, 줄기 및 가지의 껍질이다. Bark of roots, stems and branches of Acanthopanax sessiliflorum and related plants.
이 약의 주 성분중 약리작용이 강한 것은 아칸토사이드 A~D(acanthoside A~D), 세사민(sesamin), 사비닌(savinin), 리간스(lignans), 키이사노사이드(chiisanoside), 이소키이사노사이드(isochiisanoside), 키이사노게닌(chiisanogenin) 등이며, 이들 성분중 acanthoside B, D의 생물화성은 그 작용의 강도가 대단히 높다. 상기 acanthoside B, D는 유도간장애에서 오는 S-GOT, S-GPT의 병태적인 상승을 빠른 속도로 회복시키고 간상해동물에 대해서 브로모설포프탈레인 리텐션 당량(BSP, Bromosulfophthalein retention equivalent)를 정상화 시켜주며 라이프 스팬(life span)을 연장시키며 생체내에서의 이물의 대사속도를 항진시키는 작용을 한다. 한편, 상기 성분중 acanthoside D는 항지간작용의 효과가 있으며, 키이사노사이드(chiisanoside)는 항히스타민(anti-histamine)활성, 에페드린(ephedrine)과 알록산(alloxan) 유도당뇨에 대해 혈당강하 작용, 카본테트라클로라이드(carbon tetrachloride)에 의해 유도된 간의 파렌키말세포(parenchymal cell)의 손궤를 막는 효과가 있다. The major pharmacological agents of this drug are acanthoside A ~ D, sesamin, savinin, lignans, chiisanoside and isoside. It is an isochiisanoside and a chiisanogenin, and the biochemical property of acanthoside B and D among these components is very high in intensity of action. The acanthosides B and D rapidly recover the pathological elevation of S-GOT and S-GPT from induced hepatic impairment and normalize the bromosulfophthalein retention equivalent (BSP) to the injured animal. It helps to prolong life span and promote metabolism in foreign body. On the other hand, acanthoside D has the effect of anti- interstitial action, chiisanoside has antihistamine activity, hypoglycemic action against ephedrine and alloxan induced diabetes, There is an effect of blocking the hand of the parenchymal cells of the liver induced by carbon tetrachloride (carbon tetrachloride).
일반적으로 상기 오가피 성분들은 논스페시픽아답테이션엑티비티(non-specific adaptation activity)가 강해서 주로 강장목적에 사용된다. In general, the organ components are used for tonic purposes because of their strong non-specific adaptation activity.
11. 산약(山藥, Dioscoreae Rhizoma)11. Mountain medicine (山藥, Dioscoreae Rhizoma)
참마(Dioscorea japonica) 또는 마(Dioscorea batatas)의 뿌리줄기의 주피를 제거하고 그대로 또는 쪄서 말린 것으로, 한쪽이 뾰족한 방추형의 적색을 한 과실이다. It is dried or steamed and removed from the root stem of the yam ( Dioscorea japonica ) or hemp ( Dioscorea batatas ), and has one pointed fusiform red fruit.
이 약의 성분은 디하이드로엑티니디올라이드(Dehydroactinidiolide), 사프라놀(safranal), β-조논(β-jonone), 메가스티그마트리에논(megastigmatrienone), 3-하이드록시-β-이오논(3-hydroxy-β-ionone) 및 피린(pyrine), 락톤(lactone), 피롤(pyrrol) 및 여러종류의 케톤(ketone)을 함유하고, 상품의 수분함량은 13%, 리피드(lipids) 8.72%, 환원당 34.83%, 비타민 A 277.06Iu/g, 아스코빅 엑시드(ascorbic acid) 23.1㎎%, 각종 아미노산(Amino acids)을 함유하고 있다. The components of the drug are dehydroactinidiolide, safranal, β-jonone, megastigmatrienone, 3-hydroxy-β-ionone, It contains 3-hydroxy-β-ionone and pyrine, lactone, pyrrol and various ketones. The water content of the product is 13%, lipids 8.72%, It contains 34.83% of reducing sugar, 277.06Iu / g of vitamin A, 23.1mg% of ascorbic acid, and various amino acids.
이 약은 베타인(betaine) 대사물에 의해 주도되는 항지간효과와 혈압하강효과, 항혈당효과와 혈압하강효과가 있으며, 자양, 강장, 항당뇨에 응용된다. This drug has anticoagulant effect, blood pressure lowering effect, antiglycemic effect and blood pressure lowering effect led by betaine metabolite. It is applied to nourishment, tonic and antidiabetic.
12. 인진쑥(Artemisiae Capillaris Flos)12. Artemisiae Capillaris Flos
인진호(茵蔯蒿)로 통용되는데, 이는 사철쑥(Artemisia capllaris)의 꽃대를 가을에 수집하여 약용으로 사용된다. It is commonly used as Injinho, which collects the flowers of Artemisia capllaris in autumn and is used for medicinal purposes.
이약의 성분은 에스쿨레틴-6,7-디메틸에테르(Esculetin-6,7-dimethylether)가 담즙분비작용의 주효물질로 알려져 있고, 정유는 전초에 0.2%, 과수에는 1%가 함유되어 있다. 과실에는 에스쿨레틴-6,7-디메틸에테르(Esculetin-6-7-dimethylether), 1-(2-메톡시페닐)-2,4 헥사디인(1-(2-methoxy-phenyl)-2,4 hexadiyne, 노르-카필렌(nor-capillene), 카필라놀(capillanol), 카필라리신(capillarisin), 메틸카필라리신(methylcapillarisin)등이 함유되어 있다. The drug consists of Esculetin-6,7-dimethylether (Esculetin-6,7-dimethylether) is known as the major biliary secretion, essential oils contain 0.2% in starch, 1% in fruit trees. Fruits include esculetin-6-7-dimethylether, 1- (2-methoxyphenyl) -2,4 hexadiyne (1- (2-methoxy-phenyl) -2 4, hexadiyne, nor-capillene, capillanol, capillarisin, methyl capillarisin, and methyl capillarisin.
이 약은 최근에 이르러 이담작용물질로 카필라리신(capillarisin)과 그의 메틸에테르(methylether)가 존재함이 보고되고 있고, 6,7-디메틸레스쿨레틴(6,7-dimethylesculetin)의 담즙일비촉진 항염, 진통효과가 있으며, 한방에서는 이뇨, 이담, 해열제로서 황달, 간염, 식중독, 신장염 등의 치료에 이용된다. Recently, the drug has been reported to contain capillarisin and its methylether as an biliary antagonist, and to prevent bile-promoting anti-inflammatory of 6,7-dimethylesculetin (6,7-dimethylesculetin). It has an analgesic effect and is used in the treatment of jaundice, hepatitis, food poisoning and nephritis as a diuretic, diarrhea and antipyretic.
13. 당귀(當歸, Angelicae Gigantis Radix)13. Angelicae Gigantis Radix
참당귀(Angelica gigas Nakai)의 꽃피기전의 뿌리를 건조한 것으로 성상은 굵고 짧은 주근에서 갈라저 난 여러개의 가지뿌리로 되어 있으며 주근의 위쪽에는 줄기 및 잎의 잔기가 남아있다. 이약은 특히한 방향성냄새가 있는데 주근 및 가지뿌리에 있는 피목(皮目)은 정유가 스며나와 흑색으로 되어 있고 생약전체는 쭌득쭌득하며 맛은 약간 쓰다.Dried roots of the Angelica gigas Nakai before flowering, and the appearance is composed of several branch roots separated from the coarse and short roots, and the residues of stems and leaves remain on the upper part of the roots. This medicine has a particularly aromatic smell. The roots of the roots and roots are soaked with essential oils, and the whole herb is chewy and slightly bitter.
이약의 성분은 주가 정유이며 뿌리에 0.31%, 과실에는 0.69%를 함유하고 있다. It is a staple oil and contains 0.31% in root and 0.69% in fruit.
뿌리 성분은 피란코우마린(pyrancoumarin)계의 디쿠르신(decursin)을 주로 함유하고 기타 노다케닌(nodakenin), 디쿠르시놀(decursinol), 노다케내틴(nodakenin), 움벨리페론(umbelliferone), 임페라토린(imperatorin), β-시토스테롤(β-sitosterol)이 함유되어 있고, 과실에서는 디쿠르시놀(decursinol), 이소-임페라토린(iso-imperatorin), 디쿠르시딘(decursidin)이 함유되어 있다. The root component mainly contains pyrancoumarin-based decursin, and other nodakenin, decursinol, nodakenin, umbelliferone, and imperatorin (imperatorin), β-sitosterol (β-sitosterol) is contained, and the fruit contains dicursinol (decursinol), iso- imperatorin ( iso- imperatorin), dicursidin (decursidin).
이 약의 주 성분중 디쿠르신(decursin)과 디쿠르시놀(decursinol)은 토끼의 적출장관 및 심장에 대해 그 운동을 마비시키고 혈압강하 및 호흡억제작용이 있고 적출자궁에서는 전자는 비교적 흥분적으로, 후자는 억제적으로 작용한다. Decursin and decursinol, the main constituents of this drug, paralyze the movement of the rabbit's extraction tract and heart, reduce blood pressure and respiratory depression. The latter acts depressively.
이 약은 빈혈, 활혈효과가 있어 혈행장애에 의한 부인과 제 질환에 쓰이며 기타 보혈강장, 진통 등에 쓰인다. This drug has anemia and anemia effect, so it is used for gynecological diseases caused by hemostatic disorders.
14. 황정(黃精, Polygonati Rhizoma)14. Hwangjeong (黃 精, Polygonati Rhizoma)
이 약은 시베리아둥굴레(Polygonatum sibiricum REDOUTE)의 근경을 그대로 또는 쪄서(一蒸) 말린 것이다. 이 약의 성상은 구부러진 원주형 또는 덩어리 모양으로 길이 6~20㎝, 지름 1~3㎝이다. 바깥면은 황백색~황갈색으로 가로로 마디가 있고 반투명하다. 이 약은 냄새는 단내가 약간 있고 맛은 달며 씹으면 끈적끈적하다. This drug is dried or steamed from the root of Polygonatum sibiricum REDOUTE. This drug is bent cylindrical or lump shaped, 6-20cm long, 1-3cm in diameter. The outer surface is yellowish white to yellowish brown with a node in transverse and translucent. This medicine has a slight sweet smell, tastes sweet, and sticky when chewed.
이 약의 주요성분은 알칼로이드(alkaloid), 당, 점액, 아미노산, 전분 등이며, 황정의 전제(煎劑)를 토끼에 경구투여하면 혈당량은 처음에는 정상, 점차 증가를 보이며 후에는 하강한다. 또한, 마취된 개를 실험동물로 하여 혈압강하작용이 있으며 황정의 침액은 아드레날린 염산에 의한 혈당과다를 뚜렷하게 억제하는 효과가 있다. 또한 바실러스 티피(Bacullus typhi), 스타필로코커스 아우레우스(Staphylococcus aureus)에 대하여 항균작용이 있고 특히 피부진균에 대하여도 억제작용이 있으며, 죽상동맥경화를 방지하고 간세포의 지방침윤을 예방하는 효과가 있다. The main components of this drug are alkaloids, sugars, mucus, amino acids, starch, etc. When the oral administration of Hwang Jung (煎劑) is administered orally to rabbits, the blood sugar level is normal, gradually increases, and then decreases. In addition, anesthetized dogs have a blood pressure-lowering effect as experimental animals, and salivary sap has the effect of clearly inhibiting hyperglycemia caused by adrenaline hydrochloric acid. In addition, it has antibacterial activity against Bacullus typhi and Staphylococcus aureus, and especially against skin fungi, and prevents atherosclerosis and prevents hepatic limbus. have.
이 약은 주로 자양, 강장약으로 병후허약증, 폐결핵의 해수, 당뇨병의 구갈(혈당과다)등에 쓰인다. This drug is mainly nourishment and tonic medicine, used for post-mortem weakness, pulmonary tuberculosis seawater, and diabetes mellitus (excess blood sugar).
유사생약으로 진황정, 둥굴레, 완둥굴레, 퉁둥굴레, 죽대, 각시둥구레, 한라각시둥굴레, 산둥굴레, 큰둥굴레, 용둥굴레 등이 있다. Similar herbal medicines include jinhwangjeong, donggulge, dongdonggul, dongdongggul, bamboo stick, gagdonggung, halla gagdonggul, shandongggul, bigonggul, and dragongung.
15. 함초(鹹草)15. Hamcho
함초(鹹草)는 우리나라 서해안 개펄에 자라는 한해살이 풀로서 우리말로는 퉁퉁마디라고 부른다. 함초는 지구상에서 유일하게 마닷물을 머금는 식물로서 소금을 비롯, 바닷물에 녹아있는 모든 미량원소가 흡수 · 농축되어 있으므로 그 맛이 짜고 무게가 많이 나간다. Hamcho is an annual herb that grows on Gaphal on the west coast of our country. The seaweed is the only plant in the world that contains seawater, and all salts and other trace elements dissolved in seawater are absorbed and concentrated.
함초가 가지는 주성분은 효소와 미네랄로서 칼슘, 마그네슘, 칼륨, 철, 인, 망간, 아연, 요오드, 구리, 니켈, 크롬, 코발트, 바나듐, 나트륨, 염소, 우론산 및 천연섬유질을 다량 함유하고 있고, 일반성분으로는 수분, 회분, 소금(회분중), 조단백질, 조지방, 탄수화물 등을 함유하고 있으며, 비타민 B1, B2, 비타민 C, 비타민 E, 나이아신 및 알칼로이드를 함유하고 있다. 이 외에도 아미노산(amino acid)으로 글루타민산, 아스파틱산, 티로신, 리신, 타우린, 베타인, 콜린 및 프롤린을 다량 함유하고 있다. 이 외에도 바닷물속에 들어 있는 각종 미네랄이 골고루 들어 있다. Its main ingredients are enzymes and minerals containing calcium, magnesium, potassium, iron, phosphorus, manganese, zinc, iodine, copper, nickel, chromium, cobalt, vanadium, sodium, chlorine, uronic acid and natural fiber. Common ingredients include moisture, ash, salt (in ash), crude protein, crude fat, carbohydrates, and vitamin B1, B2, vitamin C, vitamin E, niacin and alkaloids. In addition, amino acids (glutamic acid, aspartic acid, tyrosine, lysine, taurine, betaine, choline and proline are contained in large amounts. In addition, it contains various minerals in seawater.
상기와 같이 바닷물이 가지고 있는 모든 미량원소를 함유하고 있는 함초의 효과는 다양하다. 그 예로서 함초의 분말에는 62%정도 함유되어 있는 식이섬유는 대장에서 당과 콜레스테롤의 흡수를 저해하여 혈당치의 상승을 제어하는 효과가 있고, 또한, 함초에 함유되어 있는 콜린(choline)은 식품으로 복용시 체내 아세틸콜린(acetyl choline)의 수치를 높여주고, 체내 부교감신경을 항진시켜주는 역할을 한다. 체내 부교감신경이 작용하게 되면 이자의 랑게르한스섬 베타에서 인슐린의 분비가 일어나게 되고, 상기 인슐린은 체내 당으로부터 글리코겐을 함성하여 혈당량을 하강시켜 당뇨병의 예방 및 치료의 효과를 얻을 수 있다. 또한, 함초에 함유되어 있는 각종 미량원소와 효소는 장내 숙변을 없애고 몸 속의 지방질을 분해하여 몸밖으로 내보내는 작용을 하여 변비를 개선하고, 비만증이 개선되는 효과를 얻을 수 있으며, 장벽에 달라붙어 있는 숙변을 제거함으로서 심장을 튼튼하게 하고, 혈액속의 콜레스테롤과 중성지방질을 제거하여 혈액을 깨끗하게 하고 혈액순환을 좋게 하여 고혈압과 저혈압이 개선되는 효과가 있다. 이 외에도 함초는 각종 성인병의 예방 및 개선의 효과를 지니고 있으며, 자양 · 강장의 효과도 있으며, 각종 피부질환이 개선되는 효과도 또한 있고, 각종 질병의 원인이 되는 갑상선의 기능을 정상화 시켜 갑상선기능저하증이나 항진증에 모두 좋은 효과가 있으며, 식용으로 복용시 체내에서 항균작용을 하여 인체의 자연치유력을 향상시키는 효과도 또한 가지고 있다. As described above, the effects of seaweed containing all the trace elements in seawater are varied. For example, dietary fiber containing about 62% in the powder of seaweed has the effect of inhibiting the absorption of sugar and cholesterol in the large intestine and controlling the rise of blood sugar level, and choline contained in the seaweed is used as food. When taken, it increases the level of acetylcholine in the body and promotes the parasympathetic nerve in the body. When the parasympathetic nerve acts in the body, insulin secretion occurs in the Langerhans Island beta of interest, and the insulin may be glycogen-containing from the body sugar to lower the blood sugar level, thereby preventing and treating diabetes. In addition, various microelements and enzymes contained in the seaweed can remove bowel intestinal stool, break down fat in the body and send it out of the body to improve constipation, improve obesity, and stool that sticks to the barrier. By removing the heart to strengthen, remove the cholesterol and triglycerides in the blood to clean the blood and improve blood circulation has the effect of improving high and low blood pressure. In addition, the seaweed has the effect of preventing and improving various adult diseases, nourishing and tonic effects, and also improving the various skin diseases, and normalizes the function of the thyroid gland, which causes various diseases, to reduce hypothyroidism. It has a good effect on both hyperlipidemia, and also has the effect of improving the body's natural healing power by taking antibacterial action in the body when taken for food.
16. 톳16. 톳
갈조식물 모자반과의 바닷말로서 이 식물은 다량의 요오드를 함유하고 다른 해조류에 비해 비타민 A, 철, 칼슘 등의 무기염류가 다량 함유되어 있어, 혈관경화를 막아주고, 상용으로 먹으면 치아가 건강해지며 머리털이 윤택해지고, 임신부인 경우에는 태아의 뼈를 튼튼하게 해주는 등의 효과가 있다. It is a sea horse with brown algae Mabanban, which contains a large amount of iodine and contains a large amount of inorganic salts such as vitamin A, iron, and calcium compared to other seaweeds. This moisturizes, and in the case of pregnant women has the effect of strengthening the bones of the fetus.
이상 상술한 바와 같이, 본 발명에 의해 달성된 건강보조식품 조성물은 곡물류 및 종실류에 특정 생약재들을 첨가하여 당뇨병과 같은 성인병의 원인이 되는 제반 요인들을 해소하여 혈당을 조절하거나 혈압을 강하시키는 효과가 있어 충분한 영양 공급 및 질병의 예방 또는 치료의 간접적인 효과가 있다. As described above, the health supplement composition achieved by the present invention has the effect of controlling the blood sugar or lowering blood pressure by eliminating all factors causing adult diseases such as diabetes by adding certain herbal medicines to cereals and seeds. There is an indirect effect of sufficient nutrition and prevention or treatment of the disease.
또한, 본 발명은 종래 의약품에 의존한 당뇨병 치료 및 예방에 있어서와 같은 약물 부작용을 일으키지 않고 당뇨병 개선, 즉 혈당의 강하 효과와 혈압하강효과를 얻을 수 있다.
In addition, the present invention can achieve diabetes improvement, that is, the effect of lowering blood sugar and lowering blood pressure without causing drug side effects as in the treatment and prevention of diabetes depending on conventional medicines.
Claims (6)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020030073170A KR100591539B1 (en) | 2003-10-20 | 2003-10-20 | Dietary supplement composition |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020030073170A KR100591539B1 (en) | 2003-10-20 | 2003-10-20 | Dietary supplement composition |
Publications (2)
Publication Number | Publication Date |
---|---|
KR20050037890A KR20050037890A (en) | 2005-04-25 |
KR100591539B1 true KR100591539B1 (en) | 2006-06-21 |
Family
ID=37240484
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1020030073170A KR100591539B1 (en) | 2003-10-20 | 2003-10-20 | Dietary supplement composition |
Country Status (1)
Country | Link |
---|---|
KR (1) | KR100591539B1 (en) |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100920494B1 (en) * | 2007-09-21 | 2009-10-08 | 전라북도 고창군 | Manufacturing Method for Bokbunja Tea Using Berry and Leaf of Rubus coreanus Miquel |
KR101217578B1 (en) * | 2009-11-16 | 2013-01-03 | 최형찬 | Making process of healthcare food containins inulin and isoflavon |
KR101312957B1 (en) | 2013-02-20 | 2013-10-01 | (주)한지 | A red onion pill and its manufacturing method |
KR101373090B1 (en) | 2012-02-13 | 2014-03-17 | 고광길 | A dietary attractive pill and making method of it |
KR101485261B1 (en) * | 2013-11-07 | 2015-01-21 | 육은자 | Composition for rolling pills comprising adlay and rolling method thereof |
CN104286874A (en) * | 2014-10-30 | 2015-01-21 | 范鹏琳 | Health porridge for reducing blood glucose |
KR20200118671A (en) | 2019-04-08 | 2020-10-16 | 재단법인 전남생물산업진흥원 | Composition comprising the extract of Jerusalem artichoke and leaves or 3-Hydroxy-8β-tigloyloxy-1,10-dehydroariglovin compounds isolated there from preventing or treating immune checkpoint inhibitor |
KR20210007022A (en) | 2021-01-11 | 2021-01-19 | 재단법인 전남바이오산업진흥원 | Composition comprising the extract of Jerusalem artichoke and leaves or 3-Hydroxy-8β-tigloyloxy-1,10-dehydroariglovin compounds isolated there from preventing or treating immune checkpoint inhibitor |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20060041438A (en) * | 2004-11-09 | 2006-05-12 | 이호운 | Functional food for regulating blood sugar including yerusalem artichoke |
KR100679698B1 (en) * | 2005-04-27 | 2007-02-06 | 김종태 | An extract of Pterocarya paliurus with blood sugar level-lowering activity and functional food comprising the same |
KR100853940B1 (en) * | 2007-02-20 | 2008-08-25 | 유상훈 | Anti-obesity constituents made by fermented tangle, salty pasture, laver, soybean |
KR100919163B1 (en) * | 2007-07-26 | 2009-09-28 | 박형희 | Ripenung jerusalem artichoke using artemisia's essence and it's manufacturing method |
-
2003
- 2003-10-20 KR KR1020030073170A patent/KR100591539B1/en not_active IP Right Cessation
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100920494B1 (en) * | 2007-09-21 | 2009-10-08 | 전라북도 고창군 | Manufacturing Method for Bokbunja Tea Using Berry and Leaf of Rubus coreanus Miquel |
KR101217578B1 (en) * | 2009-11-16 | 2013-01-03 | 최형찬 | Making process of healthcare food containins inulin and isoflavon |
KR101373090B1 (en) | 2012-02-13 | 2014-03-17 | 고광길 | A dietary attractive pill and making method of it |
KR101312957B1 (en) | 2013-02-20 | 2013-10-01 | (주)한지 | A red onion pill and its manufacturing method |
KR101485261B1 (en) * | 2013-11-07 | 2015-01-21 | 육은자 | Composition for rolling pills comprising adlay and rolling method thereof |
CN104286874A (en) * | 2014-10-30 | 2015-01-21 | 范鹏琳 | Health porridge for reducing blood glucose |
KR20200118671A (en) | 2019-04-08 | 2020-10-16 | 재단법인 전남생물산업진흥원 | Composition comprising the extract of Jerusalem artichoke and leaves or 3-Hydroxy-8β-tigloyloxy-1,10-dehydroariglovin compounds isolated there from preventing or treating immune checkpoint inhibitor |
KR20210007022A (en) | 2021-01-11 | 2021-01-19 | 재단법인 전남바이오산업진흥원 | Composition comprising the extract of Jerusalem artichoke and leaves or 3-Hydroxy-8β-tigloyloxy-1,10-dehydroariglovin compounds isolated there from preventing or treating immune checkpoint inhibitor |
Also Published As
Publication number | Publication date |
---|---|
KR20050037890A (en) | 2005-04-25 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
KR101738912B1 (en) | Composition For Anti-obesity And Diet | |
CN107259571A (en) | One kind is for canteen thing and preparation method thereof | |
CN110447902B (en) | Composition with weight-losing effect | |
CN104082672B (en) | A kind of health-preserving porridge with effect of lowering blood sugar and preparation method thereof | |
KR100591539B1 (en) | Dietary supplement composition | |
KR101445097B1 (en) | The fish gruel and manufacturing method of fish gruel | |
US20200147166A1 (en) | Health supplement food for promotion of hair growth, mitigation and alleviation of hair loss, regulation of blood glucose, and alleviation and relief of gastric disorder symptoms | |
KR100947278B1 (en) | A carbohydrate and lipid absorption inhibitory nelumbo composition and its manufacturing process thereof | |
KR101632794B1 (en) | METHOD OF MANUFACTURING PILL COMPRISED OF Protaetia brevitarsis seulensis | |
KR100649128B1 (en) | Manufacturing method of functional food composition including maesil | |
KR20070000573A (en) | The heath food having an effect on dropping blood sugar and constipation | |
KR20040095949A (en) | Composition comprising herb with usage to prevent obeseness | |
KR100923043B1 (en) | Blood pressure therapeutic agent for chinese medicine and manufacture method thereof | |
CN110214902A (en) | A kind of children's correction partial eclipse type selenium-rich complete nourishing powder | |
KR100503208B1 (en) | Diet-food composition | |
KR101479228B1 (en) | chicken soup | |
KR20090038595A (en) | Healthy filling composite for korea tradition sausage and korea tradition sausage process using the same | |
KR101053064B1 (en) | Supplements for skin improvement using edible snails, eel bone and herbal medicine | |
KR102215936B1 (en) | Functional Food Composition Ssangwhatang for Fatigue Recovery comprising Chestnut and Manufacturing method of thereof | |
CN103689561A (en) | Health-preserving health food formula beneficial for reducing lipid and losing weight and preparation method thereof | |
CN105815738A (en) | Product assisting in lowering blood glucose and preparation method thereof | |
CN106974285B (en) | Traditional Chinese medicine composition and application thereof | |
CN108433051A (en) | A kind of digestant natural functional foods of tranquilization, stomach nourition | |
KR102539641B1 (en) | Kalguksu using native grass and method for manufacturing the same | |
KR102414169B1 (en) | Digestive medicine composition for women and digestive medicine producted by the same |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A201 | Request for examination | ||
E902 | Notification of reason for refusal | ||
E701 | Decision to grant or registration of patent right | ||
GRNT | Written decision to grant | ||
FPAY | Annual fee payment |
Payment date: 20090608 Year of fee payment: 4 |
|
LAPS | Lapse due to unpaid annual fee |