KR100545435B1 - 인돌린 유도체 및 5-ｈｔ2 수용체 리간드로서의 이들의 용도 - Google Patents

인돌린 유도체 및 5-ｈｔ2 수용체 리간드로서의 이들의 용도 Download PDF

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Publication number
KR100545435B1
KR100545435B1 KR1020037005300A KR20037005300A KR100545435B1 KR 100545435 B1 KR100545435 B1 KR 100545435B1 KR 1020037005300 A KR1020037005300 A KR 1020037005300A KR 20037005300 A KR20037005300 A KR 20037005300A KR 100545435 B1 KR100545435 B1 KR 100545435B1
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formula
hydrogen
alkyl
compound
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English (en)
Korean (ko)
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KR20030048437A (ko
Inventor
벤틀리조나단마크
데이빗슨제임스에드워드폴
만셀하워드랑함
몬크나타니엘쥴리어스토마스
Original Assignee
에프. 호프만-라 로슈 아게
베르날리스 리서치 리미티드
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/94—[b, c]- or [b, d]-condensed containing carbocyclic rings other than six-membered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
KR1020037005300A 2000-10-16 2001-10-12 인돌린 유도체 및 5-ｈｔ2 수용체 리간드로서의 이들의 용도 Expired - Fee Related KR100545435B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP00122539.0 2000-10-16
EP00122539 2000-10-16
PCT/EP2001/011814 WO2002044152A1 (en) 2000-10-16 2001-10-12 Indoline derivatives and their use as 5-ht2 receptor ligands

Publications (2)

Publication Number Publication Date
KR20030048437A KR20030048437A (ko) 2003-06-19
KR100545435B1 true KR100545435B1 (ko) 2006-01-24

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Application Number Title Priority Date Filing Date
KR1020037005300A Expired - Fee Related KR100545435B1 (ko) 2000-10-16 2001-10-12 인돌린 유도체 및 5-ｈｔ2 수용체 리간드로서의 이들의 용도

Country Status (15)

Country Link
US (1) US6479534B1 (enExample)
EP (1) EP1328515B1 (enExample)
JP (1) JP4047723B2 (enExample)
KR (1) KR100545435B1 (enExample)
CN (1) CN100334076C (enExample)
AR (1) AR038762A1 (enExample)
AT (1) ATE403647T1 (enExample)
AU (2) AU2002221670B2 (enExample)
BR (1) BR0114708A (enExample)
CA (1) CA2422698C (enExample)
DE (1) DE60135239D1 (enExample)
ES (1) ES2311563T3 (enExample)
MX (1) MXPA03003246A (enExample)
WO (1) WO2002044152A1 (enExample)
ZA (1) ZA200302516B (enExample)

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Also Published As

Publication number Publication date
EP1328515A1 (en) 2003-07-23
JP2004527467A (ja) 2004-09-09
CN1630636A (zh) 2005-06-22
WO2002044152A1 (en) 2002-06-06
BR0114708A (pt) 2003-07-01
ATE403647T1 (de) 2008-08-15
EP1328515B1 (en) 2008-08-06
DE60135239D1 (de) 2008-09-18
ES2311563T3 (es) 2009-02-16
CA2422698C (en) 2009-12-15
US6479534B1 (en) 2002-11-12
AU2167002A (en) 2002-06-11
JP4047723B2 (ja) 2008-02-13
AU2002221670B2 (en) 2006-11-02
AR038762A1 (es) 2005-01-26
CN100334076C (zh) 2007-08-29
ZA200302516B (en) 2004-06-30
MXPA03003246A (es) 2003-06-06
US20020183349A1 (en) 2002-12-05
KR20030048437A (ko) 2003-06-19
CA2422698A1 (en) 2002-06-06

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