KR100476731B1 - A manufactoring process of depilatory made a affected part sprayer and a pill - Google Patents

Abstract

  The present invention relates to a method for producing a hair regrowth agent consisting of a topical coating agent and a pill.

  Many factors, such as genetic factors, increased stress, diseases such as leukemia, and abuse of hair cleansers, have recently increased hair loss regardless of men, women, old women, or cows. The trend is losing. Topical coatings, oral medications, dietary supplements, gene transplants, hair transplants, etc. are being used to treat hair loss.However, these methods do not prevent continuous hair loss. Or to accelerate the production of scalp or sebum, especially with heart disease, adverse effects such as adverse effects such as had had had.

  The present invention has been invented to solve the above problems, the present invention is a method for producing a topical coating for hair regrowth using a natural extract and a pill to prepare a topical coating which is the former is mulberry leaf, white leaf, black sesame , Kelp and seaweed are mixed at a ratio of 5: 5: 1: 1: 2, and ethanol and distilled water are mixed in a ratio of 4: 1, and extracted at room temperature for 24 hours. The extracted extract is concentrated in a vacuum depressurizer at a temperature of 45 ° C. for 3 hours to obtain a greenish brown extract suitable for evaporating and spraying ethanol. The latter method of preparing a pill suitable for taking mulberry leaves, white leaves, Pine needles, black sesame seeds, goji berry, sancho and black soybeans are mixed in a 3: 3: 3: 1: 1: 1: 2 ratio, and the extract is concentrated by the method of the topical coating agent and then dried. After drying in the grinder into a powder of more than 200 mesh and then added a suitable amount of a mixture of honey and water in a ratio of 3: 7 to obtain a pill, the herbal hair regrowth prepared in this way to prevent hair loss In addition, there is an effect of promoting hair growth to enhance the hair growth function.

Description

 A manufactoring process of depilatory made a affected part sprayer and a pill}

  The present invention relates to a method for producing a hair regrowth agent consisting of a topical coating agent and a pill.

  Hair is a solid cone fiber composed of epithelial cells. It is composed of three layers of epidermis, cortex and medulla, and hair protects the skull such as UV protection and buffering action, and arsenic, an unnecessary ingredient in the body, It absorbs heavy metals such as mercury and zinc and releases them into the body.However, in recent years, males, females, olds and cows have been used for genetic factors or other factors such as increased stress, diseases such as leukemia and abuse of hair cleaner. Regardless of the increase in hair loss phenomenon, the age of starting hair loss is gradually decreasing.

  There are various methods for the treatment of hair loss, such as topical coatings, oral medications, dietary supplements, gene transplant surgery, hair transplant surgery and alternative medicine, but these methods do not prevent continuous hair loss, The drug treatment effect is temporary, and there have been discontinuations with side effects such as adverse effects on heart disease patients.

  The present invention has been invented to solve the above problems, the present invention relates to a topical coating for spraying using a natural extract and a method for preparing a convenient pill, the former topical coating is mulberry leaf, white leaf, black Mix sesame seeds, kelp, and seaweed in a ratio of 5: 5: 1: 1: 2, and then add appropriate amount of ethanol and distilled water in a ratio of 4: 1, and extract them at room temperature (15-20 ℃) for 24 hours. Method of extracting the extracted extract was carried out twice in a vacuum vacuum evaporator (Rotary vacuum evaporator) maintained at a temperature of 45 ℃ for 3 hours to concentrate to evaporate the ethanol and to prepare an extract of a concentration suitable for spraying greenish brown The latter pill is composed of mulberry leaves, cypress leaves, pine needles, black sesame seeds, goji berry, Sancho, black beans in a ratio of 3: 3: 3: 1: 1: 2 and extracted and concentrated in the same manner as described above.Then, put it into a dryer and dry it, put it in a grinder to make powder, and then add a proper amount of the mixed solution of honey and water in the ratio of 3: 7 to make it into a convenient pill to be molded and dried.

  The manufacturing method of the present invention will be described in detail with reference to FIGS. 1 and 2 as follows.

  1. First, a method of preparing a topical coating agent and an embodiment thereof based on FIG. 1 will be described.

In the material selection process (1) which is the 1st process, 4.15 kg of mulberry leaves, 4.15 kg of cypress leaves, 0.83 kg of black sesame seeds, 1.5 kg of seaweed, and 1.5 kg of seaweed are selected at a ratio of 5: 5: 1: 1: 2.

In the mixing process (2) which is a 2nd process, the raw material selected in the 1st process is thrown into a mixer, and it mixes.

In the third step, the extraction step (3) was performed in the second step, and 40 liters of ethanol (3-1) and 10 liters of distilled water (3-2) were added and extracted at room temperature for 24 hours. Get

The fourth step is a vacuum concentrating step (4), the extract obtained in the third step is put into a vacuum vacuum evaporator (concentrator) and concentrated at a temperature of 45 ℃ for 3 hours to evaporate the ethanol (4-1) contained therein 40 liters of a greenish brown extract are obtained which are suitable for post spraying.

The fifth step is a product completion step (5), and the product obtained by the fourth step is inspected and then packaged.

  2. Next, the manufacturing method and embodiment of a pill according to FIG.

In the material selection process (101), which is the first step, 3 kg of mulberry leaves, 3 kg of cypress leaves, 3 kg of pine needles, 1 kg of black sesame seeds, 1 kg of wolfberry, 2 kg of Japanese pepper, 2 kg of black beans, and 2 kg of 3: 3: 3: 1: 1: 1: 1: 2 Select.

In the mixing process 102 which is a 2nd process, the raw material obtained by the 1st process 101 is thrown into a mixer, and it mixes sufficiently.

In the extraction step (103) which is the third step, 40 liters of ethanol (103-1) and 10 liters of distilled water (103-2) were added to the one obtained in the second step, and the extraction was performed at room temperature for 24 hours. Obtain the extract.

In the vacuum packing step 104, which is the fourth step, the extract extracted in the third step is put in a vacuum concentrator and heated for 2 hours at a temperature of 45 DEG C for 104 hours to evaporate the ethanol 104-1 contained therein. 60 kg of extract suitable for pilling is then obtained.

The fifth step is a drying step 105, which is obtained in the fourth step, is put into a vacuum drier, and heated (105-2) for about 1 hour to give 40 kg of solids having a moisture content of less than 10%.

In the sixth step, as the grinding step 106, the dried product obtained in the fifth step is put into a grinder to be pulverized at 200 mesh or more.

In the seventh step, as the compounding step 107, 10 l of a mixture of honey 107-1 and water 107-2 in a 3: 7 ratio is added to the blender obtained in the sixth step.

In the eighth step, as the molding step 108, 40 kg of pills suitable for taking into the pill molding machine obtained in the seventh step are obtained and then dried at room temperature for 24 hours.

The ninth step is a package after the inspection of the one obtained in the eighth step as the completion step 109.

  The extract obtained as described above uses a herbal medicine as described above. As a pharmacological effect of such herbal medicine on the human body, it promotes hair growth and metabolism of the scalp, prevents hair loss, and has hair growth promoting effect. have. In particular, in the manufacturing process of topical coatings and pills, extracting the pharmacological components contained in the medicine as an extract, refrigerated or dried and granulated to obtain more active energy in a small amount to increase the hair growth promoting effect relatively Can be.

  Looking at the ingredients contained in the herbal material of mulberry leaf, baekbaek leaf, pine needles, black sesame seeds, black beans, wolfberry, kelp, etc. of the composite extract adopted in the present invention,

Mulberry is used as a medicinal herb as the upper limbs (어린), leaves and upper leaves (桑葉) fruit, inlaid persimmon (桑 堪 子) root bark is called baekbaekpi (桑白皮). Among them, the mulberry leaves, roots, bark and root bark of the mulberry has been shown to be effective in preventing hair formation and hair loss. In particular, the mulberry leaves contain flavonoids rutin, quercetin, isoquercetin, moracetin and insect transformation hormones inokosterone and ecdysterone.

  These mulberry leaves have a protein content of 25-35%, and they contain a large amount of protein next to soybeans.In addition, about 0.25% of essential oils, minerals such as iron and manganese, vitamins B1, C, and about 25 protein amino acids It contains glutamic acid, aspartic acid, Iysine, Isoleucine, and methionine. This kind of amino yarn content is shown to be very similar to the amino acid composition of hair.

  In addition, β-sitosterol, among the lipids of mulberry leaves, reduces cholesterol levels by increasing cholesterol (cholesterol) release, and rutin, also called vitamin P, with 50 kinds of inorganic ingredients such as Ca, K and Fe, is a natural bioactive substance. It has been known as a plant widely used in the field of food and cosmetics since it has an effect of inhibiting various adult diseases and aging, such as strengthening capillaries and improving elasticity of blood vessels.

The cypress leaves are known to protect the hair's strength. The cypress leaves contain aromanderin, quercetin, amenthoflavone, myricetin and hinokiflavone.

Black sesame is a popular natural remedy that is preferred by those who suffer from hair loss and baldness in Japan and China. In particular, in order to improve the quality of hair, black sesame must be strengthened and blood circulation must be promoted. Black sesame has been a favorite food.

  Black sesame seeds are rich in high-quality protein and contain vitamin E-containing linolenic acid, calcium, vitamins B1, B2 and iron, which provide the hair with nutrition and reduce blood cholesterol levels. In addition, unsaturated fatty acids such as linoleic acid and linolenic acid, which are rich in black sesame, soften blood, and vitamin E regulates metabolism such as promoting blood flow in peripheral blood vessels.

  In particular, tryptophan, which is contained in black sesame, works to cleanse the skin and shine the hair. In addition, "lecithin", the main ingredient of black sesame seeds, helps to transport fat, promotes blood circulation in capillaries, provides the necessary nutrients to the root of the hair, and prevents cholesterol from accumulating in the body. It is known that the effect is also strengthening kidney function.

Black beans have been widely used in our country to strengthen hair. Soybeans have a good detoxification since ancient times, and soybeans have natural ingredients similar to female hormones, which are effective in preventing osteoporosis. In particular, the salty black soybean is known to have a good effect in preventing hair loss caused by weak kidney and bladder when seen in herbal reproductive therapy. This is because soy is high in protein, potassium, calcium, iron, etc. are rich in minerals and plant fiber, such as vitamin B.

  In addition, soybeans provide abundant phytoestrogens that exhibit estrogenic effects, such as preventing hormone-related diseases. Among soy isoflavones, genistein inhibits tyrosine kinase, which is closely related to cell division. It is well known as a compound.

Studies on the human physiological function of seaweed have been shown to have anticancer, antithrombotic, heavy metal and radioactivity in vitro. Kelp and seaweed, which are representative edible algae, contain nutrients such as protein, lipids, vitamins, and inorganic ingredients such as Ca and I, and phytoestrogen and flavonoid, which are substances that inhibit the production of DHT. It contains a lot.

  In particular, sea tangle and kelp are supplied with excellent calcium (Ca) of 0.98%, and contain 50 kinds of minerals such as 0.46% of magnesium (Mg) and 100ppm of iron (Fe). It is. In addition, kelp is rich in iodine (I), which is the main raw material of thyroid hormone, which is involved in all physiological metabolism of the human body, and is rich in alginate fiber, which is excellent in absorbing harmful heavy metals, excess salt, and extracorporeal release of cholesterol. It is contained (30%), so it is the best alkaline food and the effect of improving the constitution is a fast food.

One of the pharmacological actions of Gojija (학 子) (Lycium chinense Mill (Solanaceae)) is highly regarded as an alkaline food. When the human body is originally acidified, the resistance to disease becomes weak, so people tend to ask for all kinds of diseases, and as people enter middle age, this tendency is more severe.Goji itself is a strong alkaline food, which neutralizes the acidification of the human body to strengthen disease resistance. It also acts to strengthen blood pressure. In particular, it is believed that the added ingredients evenly supply nutrients to act on the hair follicle epithelium and peripheral blood vessels to activate capillary cells to promote hair production and improve scalp. As a pharmacological ingredient of these wolfberry betaine crystalline alkaloids are a kind of amino acid, which is good for the liver, which is responsible for metabolism of the human body, and psarin and xanthine are carotene, which enters the body and turns into vitamin A. It is a nutrient for cultivating growth and resistance to disease, and rutin promotes capillary action to prevent internal bleeding and fundus appearance.

  In addition, beta sitosterol is excellent in inhibiting the absorption of cholesterol, and is effective in the treatment of prostate hypertrophy, suppressing the formation of high lipoproteins, and thus preventing and preventing adult diseases caused by cholesterol and high fat.

  And one embodiment of the present invention

  1. In the subjects and the period of spray and dosing, 6 subjects of the topical coating agent of the present invention prepared by the method described above were sprayed at 3 ml for 8 months from February 2001 to the end of September, It was sprayed twice in the morning and evening (2times). At the same time, the topical coating extract and honey were rotted in the same amount of 20 ml, and the extract was not a problem even when irritating the spray site with a relatively safe substance.

  And the pill prepared by the above method was to take 40 tablets at a time three times a day after breakfast, lunch, dinner after 8 months from February to the end of September 2001.

  2. Hair growth promotion test

(1) scalp change process shooting

  As described above, the scalp scaling was performed simultaneously while spraying or taking the topical coating agent and the pill of the present invention. Scalp Scaling was massaged once or twice a week using a mixture of white powder and black sesame oil. At this time, the material mixed with 15 ml of the white leaf powder and 17 ml of black sesame oil was steamed on the local scalp for 15 minutes by an ozone steamer at room temperature at 45 ° C., left for 5 minutes and washed with foaming shampoo.

  The scalp change process according to the application of the sample was compared and confirmed by taking a photograph every 1 to 2 months before and after use.

(2) changes in the condition of the scalp and hair

  To investigate the change of hair condition, double vacuum deposition was performed by attaching to stub under an anatomical microscope (X20, Nikon, Japan). Specifically, the film was first deposited twice using a carbon coater (K950-Emtech), and platinum plated for 2 minutes using an ion coater (E-1010, HITACHI), and then a scanning electron microscope (S-3500N) at an acceleration voltage of 10 KV. HITACHI) was used.

  In the trigram method, hair was randomly extracted from each part of the head, and the state of application was divided into growth phase, degeneration phase, and resting phase under an electron microscope. In addition, the hair growth effect was determined by randomly extracting new hairs at the hair loss site and classifying the ratios into the growth phase, the degenerative phase, and the resting phase.

(3) hair production and change measurement

Self-evaluation was conducted every 3 months to increase the satisfaction of the test subjects. Each point was determined based on the center point of the forehead, and the number of hairs generated in the square shape 1cm ² was observed to examine the increase and decrease of the hair.

(4) The questionnaire about herbal medicine prescription was also parallel.

  3. Results

(1) Hair distribution and numerical comparison

Maintaining mulberry leaf and cypress leaf as the main ingredients of the topical application hair regrowth and pill hair regrowth of the present invention to six subjects showing signs of hair loss in the same manner as in the above method for 6 months after the spray and dose, precise hair promotion effect As a result of photo analysis, the number of head parts per 1cm ² was as follows.

  This remarkable hair grows again and affects the hair growth cycle, resulting in changes in hair thickness, length, growth rate and duration. It was confirmed that the number of hair growth was significantly increased.

  As described above, the present invention is a hair regrowth agent using extracts of natural herbal medicines such as mulberry leaf, baekbaek leaf, black sesame, kelp, seaweed, wolfberry, pine needles, sancho, black beans, harmless to the human body and safe, especially extracting phytoestrogens It is a very useful invention that helps the production of the hair root itself and promotes the metabolism and hair growth promoting effect of the scalp as compared to conventional hair regrowth and hair loss prevention treatment.

1 is a manufacturing process display of the topical coating agent

2 is a manufacturing process display of a pill

Claims (2)

  Mulberry leaf, cypress leaf, black sesame, kelp, seaweed, 5: 5: 1: 2: 2 in a ratio of ethanol and distilled water in a ratio of 4: 1 to extract for 24 hours at room temperature and repeated twice The extracted extract was put in a vacuum vacuum concentrator, and then concentrated at a temperature of 45 ℃ for 3 hours to evaporate ethanol to obtain a greenish brown hair extract for topical coatings, characterized in that.   Mulberry leaves, cypress leaves, pine needles, black sesame seeds, wolfberry, sancho and black beans are mixed in a 3: 3: 3: 1: 1: 1: 2 ratio, and the extract is extracted by the method of claim 1, and then the extract is dried and pulverized. A method for producing a pill hair regrowth agent, characterized in that honey and water are added to a powder in an appropriate amount of a ratio of 3: 7 to make pills and then dried for 24 hours.