KR100457748B1 - 건조에 의한 생물학적 활성 물질의 규모조절 보존방법 - Google Patents

건조에 의한 생물학적 활성 물질의 규모조절 보존방법 Download PDF

Info

Publication number
KR100457748B1
KR100457748B1 KR10-1999-7000253A KR19997000253A KR100457748B1 KR 100457748 B1 KR100457748 B1 KR 100457748B1 KR 19997000253 A KR19997000253 A KR 19997000253A KR 100457748 B1 KR100457748 B1 KR 100457748B1
Authority
KR
South Korea
Prior art keywords
preserving
substance
foam
biological activity
temperature
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
KR10-1999-7000253A
Other languages
English (en)
Korean (ko)
Other versions
KR20000023779A (ko
Inventor
브론슈타인빅토르
Original Assignee
유니버설 프리저베이션 테크놀로지스 인코포레이티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26695104&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR100457748(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 유니버설 프리저베이션 테크놀로지스 인코포레이티드 filed Critical 유니버설 프리저베이션 테크놀로지스 인코포레이티드
Publication of KR20000023779A publication Critical patent/KR20000023779A/ko
Application granted granted Critical
Publication of KR100457748B1 publication Critical patent/KR100457748B1/ko
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/04—Preserving or maintaining viable microorganisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S516/00—Colloid systems and wetting agents; subcombinations thereof; processes of
    • Y10S516/924—Significant dispersive or manipulative operation or step in making or stabilizing colloid system
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984—Microcapsule with fluid core [includes liposome]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/107497—Preparation composition [e.g., lysing or precipitation, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/108331—Preservative, buffer, anticoagulant or diluent

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Colloid Chemistry (AREA)
  • Drying Of Solid Materials (AREA)
  • Vaporization, Distillation, Condensation, Sublimation, And Cold Traps (AREA)
  • Manufacture Of Porous Articles, And Recovery And Treatment Of Waste Products (AREA)
KR10-1999-7000253A 1996-07-15 1997-07-14 건조에 의한 생물학적 활성 물질의 규모조절 보존방법 Expired - Fee Related KR100457748B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US2179696P 1996-07-15 1996-07-15
US60/021,796 1997-01-17
US8/785,473 1997-01-17
US08/785,473 US5766520A (en) 1996-07-15 1997-01-17 Preservation by foam formation
US08/785,473 1997-01-17

Publications (2)

Publication Number Publication Date
KR20000023779A KR20000023779A (ko) 2000-04-25
KR100457748B1 true KR100457748B1 (ko) 2004-11-17

Family

ID=26695104

Family Applications (1)

Application Number Title Priority Date Filing Date
KR10-1999-7000253A Expired - Fee Related KR100457748B1 (ko) 1996-07-15 1997-07-14 건조에 의한 생물학적 활성 물질의 규모조절 보존방법

Country Status (18)

Country Link
US (1) US5766520A (enExample)
EP (1) EP0914202A4 (enExample)
JP (1) JP2000515856A (enExample)
KR (1) KR100457748B1 (enExample)
CN (1) CN1116104C (enExample)
AU (1) AU714328B2 (enExample)
BR (1) BR9711808A (enExample)
CA (1) CA2260233A1 (enExample)
CZ (1) CZ7999A3 (enExample)
DE (1) DE914202T1 (enExample)
EA (1) EA001138B1 (enExample)
HU (1) HUP9903917A3 (enExample)
IL (1) IL127971A (enExample)
NO (1) NO990158D0 (enExample)
NZ (1) NZ333738A (enExample)
PL (1) PL331174A1 (enExample)
TR (1) TR199900127T2 (enExample)
WO (1) WO1998002240A1 (enExample)

Families Citing this family (97)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100291620B1 (ko) 1992-09-29 2001-10-24 추후제출 부갑상선호르몬의활성단편의폐를통한전달방법
ATE264096T1 (de) 1994-03-07 2004-04-15 Nektar Therapeutics Verfahren und mittel zur verabreichung von insulin über die lunge
US20030113273A1 (en) * 1996-06-17 2003-06-19 Patton John S. Methods and compositions for pulmonary delivery of insulin
US6290991B1 (en) 1994-12-02 2001-09-18 Quandrant Holdings Cambridge Limited Solid dose delivery vehicle and methods of making same
EP0782398A1 (en) 1994-09-22 1997-07-09 Quadrant Holdings Cambridge Limited Compositions for use in rehydration and nutrition during athletic exercise and methods of making same
US6964771B1 (en) 1995-06-07 2005-11-15 Elan Drug Delivery Limited Method for stably incorporating substances within dry, foamed glass matrices
US6509146B1 (en) 1996-05-29 2003-01-21 Universal Preservation Technologies, Inc. Scalable long-term shelf preservation of sensitive biological solutions and suspensions
US6468782B1 (en) * 1996-12-05 2002-10-22 Quadrant Healthcare (Uk) Limited Methods of preserving prokaryotic cells and compositions obtained thereby
GB9705588D0 (en) 1997-03-18 1997-05-07 Anglia Research Foundation Stable particle in liquid formulations
US20020035071A1 (en) * 1997-07-08 2002-03-21 Josef Pitha Mimicking the metabolic effects of caloric restriction by administration of glucose antimetabolites
US20060116330A1 (en) * 1997-07-08 2006-06-01 The Iams Company Methods of mimicking the metabolic effects of caloric restriction by administration of mannoheptulose
US8563522B2 (en) * 1997-07-08 2013-10-22 The Iams Company Method of maintaining and/or attenuating a decline in quality of life
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
US6565885B1 (en) 1997-09-29 2003-05-20 Inhale Therapeutic Systems, Inc. Methods of spray drying pharmaceutical compositions
US6309623B1 (en) 1997-09-29 2001-10-30 Inhale Therapeutic Systems, Inc. Stabilized preparations for use in metered dose inhalers
CA2312233A1 (en) * 1997-11-26 1999-06-03 Universal Preservation Technologies, Inc. Preservation of sensitive biological samples by vitrification
US6306345B1 (en) * 1998-05-06 2001-10-23 Universal Preservation Technologies, Inc. Industrial scale barrier technology for preservation of sensitive biological materials at ambient temperatures
US6214054B1 (en) 1998-09-21 2001-04-10 Edwards Lifesciences Corporation Method for fixation of biological tissues having mitigated propensity for post-implantation calcification and thrombosis and bioprosthetic devices prepared thereby
EP1144930A1 (en) 1999-01-05 2001-10-17 Universal Preservation Technologies, Inc. Vacuum control system for foam drying apparatus
EA004131B1 (ru) * 1999-05-04 2003-12-25 Энхайдро Лимитед Способ сохранения вирусов и микоплазмы
US6692695B1 (en) 1999-05-06 2004-02-17 Quadrant Drug Delivery Limited Industrial scale barrier technology for preservation of sensitive biological materials
CA2382061A1 (en) * 1999-08-19 2001-02-22 Victor Bronshtein Preservation of bacterial cells at ambient temperatures
AU2046101A (en) * 1999-11-22 2001-06-04 Universal Preservation Technologies, Inc. Preservation and formulation of bioactive materials for storage and delivery in hydrophobic carriers
US8404217B2 (en) 2000-05-10 2013-03-26 Novartis Ag Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
CA2382133C (en) 2000-05-10 2010-11-23 Alliance Pharmaceutical Corporation Phospholipid-based powders for drug delivery
WO2001094867A1 (en) 2000-06-07 2001-12-13 Universal Preservation Technologies, Inc. Industrial scale barrier technology for preservation of sensitive biological materials
CZ301813B6 (cs) * 2000-06-27 2010-06-30 F. Hoffmann-La Roche Ag Zpusob prípravy farmaceutické kompozice
US6537666B1 (en) * 2000-10-23 2003-03-25 Universal Preservation Technologies, Inc. Methods of forming a humidity barrier for the ambient temperature preservation of sensitive biologicals
US7153472B1 (en) * 2000-11-22 2006-12-26 Quadrant Drug Delivery Limited Preservation and formulation of bioactive materials for storage and delivery in hydrophobic carriers
US6872357B1 (en) * 2000-11-22 2005-03-29 Quadrant Drug Delivery Limited Formulation of preservation mixtures containing sensitive biologicals to be stabilized for ambient temperature storage by drying
AU2002305461A1 (en) * 2001-05-07 2002-11-18 Universal Preservation Technologies, Inc. Preservation of competent cells at ambient temperatures
US6884866B2 (en) * 2001-10-19 2005-04-26 Avant Immunotherapeutics, Inc. Bulk drying and the effects of inducing bubble nucleation
WO2003053411A1 (en) 2001-12-19 2003-07-03 Nektar Therapeutics Pulmonary delivery of aminoglycosides
US6878168B2 (en) 2002-01-03 2005-04-12 Edwards Lifesciences Corporation Treatment of bioprosthetic tissues to mitigate post implantation calcification
WO2003087327A2 (en) * 2002-04-11 2003-10-23 Medimmune Vaccines, Inc. Preservation of bioactive materials by freeze dried foam
HUE034801T2 (en) 2002-11-01 2018-02-28 Glaxosmithkline Biologicals Sa Drying procedure
US20050100559A1 (en) * 2003-11-07 2005-05-12 The Procter & Gamble Company Stabilized compositions comprising a probiotic
US20050100636A1 (en) * 2003-11-10 2005-05-12 Megan Botteri [A Low-Calorie Sports Drink For Physically Active Women That is Fortified with Iron, Calcium and Essential Vitamins for Use in Rehydration and Replacing Electrolytes Lost During Periods of Physical Activity]
US8877178B2 (en) * 2003-12-19 2014-11-04 The Iams Company Methods of use of probiotic bifidobacteria for companion animals
US7785635B1 (en) 2003-12-19 2010-08-31 The Procter & Gamble Company Methods of use of probiotic lactobacilli for companion animals
US20050158294A1 (en) * 2003-12-19 2005-07-21 The Procter & Gamble Company Canine probiotic Bifidobacteria pseudolongum
US8894991B2 (en) * 2003-12-19 2014-11-25 The Iams Company Canine probiotic Lactobacilli
US20050152884A1 (en) * 2003-12-19 2005-07-14 The Procter & Gamble Company Canine probiotic Bifidobacteria globosum
US9744227B2 (en) 2004-06-02 2017-08-29 Universal Stabilization Technologies, Inc. Compositions containing ambient-temperature stable, inactivated but therapeutically active biopharmaceuticals and methods for formulation thereof
EP2567708A3 (en) 2004-06-02 2013-10-16 Victor Bronshtein Preservation by vaporization
JP2007277094A (ja) * 2004-06-29 2007-10-25 Chemo Sero Therapeut Res Inst 改変ダニ主要アレルゲン含有医薬組成物
EP1771503B1 (en) * 2004-07-30 2014-09-03 Enwave Corporation Method for producing hydrocolloid foams
JP4938005B2 (ja) * 2005-05-31 2012-05-23 ザ・アイムス・カンパニー ネコ科動物プロバイオティックであるラクトバシラス
BRPI0611492B1 (pt) * 2005-05-31 2021-10-13 Mars, Incorporated Bifidobactéria probiótica felina
JP5214464B2 (ja) 2005-12-28 2013-06-19 アドバンスド バイオニュートリション コーポレーション 多糖類、糖類およびポリオール類の乾燥マトリックスを含む、ガラス形態の、プロバイオティクス細菌用送達媒体およびその製造方法
US8968721B2 (en) 2005-12-28 2015-03-03 Advanced Bionutrition Corporation Delivery vehicle for probiotic bacteria comprising a dry matrix of polysaccharides, saccharides and polyols in a glass form and methods of making same
US9453675B2 (en) * 2006-02-10 2016-09-27 Sp Industries, Inc. Method of inducing nucleation of a material
CN101626682B (zh) 2006-10-27 2014-04-16 爱德华兹生命科学公司 用于外科植入的生物组织
WO2008076975A1 (en) 2006-12-18 2008-06-26 Advanced Bionutrition Corporation A dry food product containing live probiotic
CA2673465A1 (en) 2007-02-01 2008-08-07 The Iams Company Method for decreasing inflammation and stress in a mammal
EP2148923B1 (en) * 2007-05-18 2012-08-22 MedImmune, LLC Preservation of bioactive materials by freeze dried foam
US9101691B2 (en) * 2007-06-11 2015-08-11 Edwards Lifesciences Corporation Methods for pre-stressing and capping bioprosthetic tissue
AU2008280755B9 (en) 2007-07-26 2014-09-25 Sanofi Pasteur Limited Antigen-adjuvant compositions and methods
EP2190974A4 (en) * 2007-09-13 2016-01-20 Enwave Corp APPARATUS AND METHOD FOR DEHYDRATING BIOLOGICAL MATERIAL
US8357387B2 (en) * 2007-12-21 2013-01-22 Edwards Lifesciences Corporation Capping bioprosthetic tissue to reduce calcification
US9771199B2 (en) 2008-07-07 2017-09-26 Mars, Incorporated Probiotic supplement, process for making, and packaging
EP2329005A4 (en) * 2008-09-12 2011-10-12 Enwave Corp DEVICE AND METHOD FOR DEHYDRATING BIOLOGICAL MATERIAL WITH FREEZERS AND MICROWAVES
CA2986751A1 (en) 2009-03-27 2010-09-30 Intervet International B.V. Microparticulated vaccines for the oral or nasal vaccination and boostering of animals including fish
AU2010254235B2 (en) 2009-05-26 2015-04-02 Advanced Bionutrition Corporation Stable dry powder composition comprising biologically active microorganisms and/or bioactive materials and methods of making
US10104903B2 (en) 2009-07-31 2018-10-23 Mars, Incorporated Animal food and its appearance
EP2475393A4 (en) * 2009-09-14 2013-08-21 Vu Truong-Le FORMULATION FOR THE ROOM TEMPERATURE STABILIZATION OF A WEAKED LIVING BACTERIAL VACCINE
CA2785815C (en) 2010-01-28 2018-04-24 Advanced Bionutrition Corporation Dry glassy composition comprising a bioactive material
US9504750B2 (en) 2010-01-28 2016-11-29 Advanced Bionutrition Corporation Stabilizing composition for biological materials
EP2674174B1 (en) 2010-03-23 2019-10-16 Edwards Lifesciences Corporation Methods of conditioning sheet bioprosthetic tissue
EP2582411B1 (en) 2010-06-17 2019-05-01 Edwards Lifesciences Corporation Methods for stabilizing a bioprosthetic tissue by chemical modification of antigenic carbohydrates
US8906601B2 (en) 2010-06-17 2014-12-09 Edwardss Lifesciences Corporation Methods for stabilizing a bioprosthetic tissue by chemical modification of antigenic carbohydrates
ES2676656T3 (es) 2010-08-13 2018-07-23 Advanced Bionutrition Corp. Composición estabilizante de almacenamiento en seco para materiales biológicos
US9351829B2 (en) 2010-11-17 2016-05-31 Edwards Lifesciences Corporation Double cross-linkage process to enhance post-implantation bioprosthetic tissue durability
US10238771B2 (en) 2012-11-08 2019-03-26 Edwards Lifesciences Corporation Methods for treating bioprosthetic tissue using a nucleophile/electrophile in a catalytic system
CA2913971C (en) 2013-05-31 2022-08-02 Universal Stabilization Technologies, Inc. Polymeric compositions containing ambient-temperature stable biopharmaceuticals & methods for formulation thereof
US9615922B2 (en) 2013-09-30 2017-04-11 Edwards Lifesciences Corporation Method and apparatus for preparing a contoured biological tissue
US10959839B2 (en) 2013-10-08 2021-03-30 Edwards Lifesciences Corporation Method for directing cellular migration patterns on a biological tissue
US9938558B2 (en) 2015-06-25 2018-04-10 Ascus Biosciences, Inc. Methods, apparatuses, and systems for analyzing microorganism strains from complex heterogeneous communities, predicting and identifying functional relationships and interactions thereof, and selecting and synthesizing microbial ensembles based thereon
US10851399B2 (en) 2015-06-25 2020-12-01 Native Microbials, Inc. Methods, apparatuses, and systems for microorganism strain analysis of complex heterogeneous communities, predicting and identifying functional relationships and interactions thereof, and selecting and synthesizing microbial ensembles based thereon
MX388995B (es) 2015-06-25 2025-03-20 Native Microbials Inc Métodos, aparatos y sistemas para analizar cepas de microorganismos de comunidades heterogéneas complejas, predecir e indentificar sus relaciones funcionales e interacciones y seleccionar y sintetizar conjuntos microbianos basados en estos.
KR102685914B1 (ko) 2015-07-29 2024-07-16 어드밴스드 바이오뉴트리션 코프. 특수 식이 용도를 위한 안정한 프로바이오틱 건조 조성물
CN109874294B (zh) 2016-04-15 2023-06-20 原生微生物股份有限公司 通过施用微生物聚生体或其纯化菌株来提高禽类的农业生产的方法
CN106434840B (zh) * 2016-12-02 2019-08-09 北京中检葆泰生物技术有限公司 一种用于微生物法定量检测维生素b12的微孔板、其试剂盒及其制备方法
CN110352250A (zh) 2016-12-28 2019-10-18 埃斯库斯生物科技股份公司 用于通过示踪剂分析法对复杂异质群落进行微生物株系分析、确定其功能关系及相互作用以及合成包括给药微生物群集和接种微生物群集的微生物群集的方法、设备和系统
AU2017386658A1 (en) 2016-12-28 2019-07-25 Native Microbials, Inc. Methods, apparatuses, and systems for analyzing complete microorganism strains in complex heterogeneous communities, determining functional relationships and interactions thereof, and identifying and synthesizing bioreactive modificators based thereon
CN106701887B (zh) * 2017-01-03 2020-01-17 北京中检葆泰生物技术有限公司 一种用于微生物法定量检测叶酸的微孔板、其试剂盒及其制备方法
CN106676160B (zh) * 2017-01-03 2020-02-21 北京中检葆泰生物技术有限公司 一种用于微生物法定量检测泛酸的微孔板、其试剂盒及其制备方法
CN106591415B (zh) * 2017-01-03 2019-12-10 北京中检葆泰生物技术有限公司 一种用于微生物法定量检测生物素的微孔板、其试剂盒及其制备方法
CN106676161B (zh) * 2017-01-03 2020-01-21 北京中检葆泰生物技术有限公司 一种用于微生物法定量检测烟酸的微孔板、其试剂盒及其制备方法
US10617756B2 (en) 2017-01-05 2020-04-14 Shimojani, LLC Drug regimen for treatment of cerebral ischemia
EP3615006A4 (en) * 2017-04-28 2020-12-30 Universal Stabilization Technologies, Inc. THERMOSTABLE ANTIGENIC POLIOMYELITIC VACCINES AND RELATED PROCESSES
CN110678590B (zh) 2017-05-31 2022-07-19 爱德华兹生命科学公司 胶原纤维和由其形成的制品
UY37939A (es) 2017-10-18 2019-04-30 Ascus Biosciences Inc Aumento de la producción de aves de corral mediante la administración de un bioensamblaje sintético de microbios o cepas purificadas de los mismos
CA3081049A1 (en) 2018-01-23 2019-08-01 Edwards Lifesciences Corporation Method for pre-stretching implantable biocompatible materials, and materials and devices produced thereby
JP7138336B2 (ja) * 2018-06-29 2022-09-16 国立大学法人九州工業大学 生体由来の水溶性高分子乾燥品の製造方法及びその製造装置
WO2020092205A1 (en) 2018-11-01 2020-05-07 Edwards Lifesciences Corporation Transcatheter pulmonic regenerative valve

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4642903A (en) * 1985-03-26 1987-02-17 R. P. Scherer Corporation Freeze-dried foam dosage form
DE229810T1 (de) * 1985-07-09 1987-11-05 Quadrant Bioresources Ltd., Soulbury, Leighton Buzzard, Bedfordshire Beschuetzung von proteinen und aehnlichem.
US5271881A (en) * 1987-09-28 1993-12-21 Redding Bruce K Apparatus and method for making microcapsules
GB8903593D0 (en) * 1989-02-16 1989-04-05 Pafra Ltd Storage of materials
US5200399A (en) * 1990-09-14 1993-04-06 Boyce Thompson Institute For Plant Research, Inc. Method of protecting biological materials from destructive reactions in the dry state
AU659645B2 (en) * 1991-06-26 1995-05-25 Inhale Therapeutic Systems Storage of materials
US5409703A (en) * 1993-06-24 1995-04-25 Carrington Laboratories, Inc. Dried hydrogel from hydrophilic-hygroscopic polymer
US5565318A (en) * 1994-09-02 1996-10-15 Pharmacia Biotech, Inc. Room temperature stable reagent semi-spheres
CZ391297A3 (cs) * 1995-06-07 1998-05-13 Quadrant Holdings Cambridge Limited Způsob přípravy tenké porovité skelné matrice a prostředek tím získaný

Also Published As

Publication number Publication date
EP0914202A4 (en) 2004-09-01
CA2260233A1 (en) 1998-01-22
CN1226842A (zh) 1999-08-25
EA199900268A1 (ru) 1999-10-28
HUP9903917A3 (en) 2000-06-28
US5766520A (en) 1998-06-16
AU714328B2 (en) 1999-12-23
EP0914202A1 (en) 1999-05-12
TR199900127T2 (xx) 1999-04-21
NO990158L (no) 1999-01-14
KR20000023779A (ko) 2000-04-25
BR9711808A (pt) 2000-01-18
NO990158D0 (no) 1999-01-14
EA001138B1 (ru) 2000-10-30
WO1998002240A1 (en) 1998-01-22
CN1116104C (zh) 2003-07-30
CZ7999A3 (cs) 1999-11-17
IL127971A (en) 2001-09-13
AU3660697A (en) 1998-02-09
PL331174A1 (en) 1999-06-21
HUP9903917A2 (hu) 2000-03-28
JP2000515856A (ja) 2000-11-28
NZ333738A (en) 2000-09-29
IL127971A0 (en) 1999-11-30
DE914202T1 (de) 2000-02-17

Similar Documents

Publication Publication Date Title
KR100457748B1 (ko) 건조에 의한 생물학적 활성 물질의 규모조절 보존방법
US6509146B1 (en) Scalable long-term shelf preservation of sensitive biological solutions and suspensions
EP1032647B1 (en) Preservation of sensitive biological samples by vitrification
EP1750760B1 (en) Preservation by vaporization
WO1998002240B1 (en) Preservation by foam formation
US20030022333A1 (en) Long-term shelf preservation by vitrification
US6872357B1 (en) Formulation of preservation mixtures containing sensitive biologicals to be stabilized for ambient temperature storage by drying
EP1141232B1 (en) Preservation of sensitive biologicial materials at ambient temperatures by vitrification
CN115024310B (zh) 一种细胞冻干保存剂及其制备方法
WO2001037656A2 (en) Preservation of sensitive biological material
CN101755044A (zh) 通过冻干泡沫保存生物活性材料
AU2009200127A1 (en) Preservation of bioactive materials by freeze dried foam
JP2002542815A (ja) ウイルスおよびマイコプラズマの保存方法
Yoshikawa et al. Extraction of trehalose from thermally-treated bakers’ yeast
CN1286725A (zh) 敏感性生物样品的玻化保质法
MXPA00005123A (en) Preservation of sensitive biological samples by vitrification
Salemink Cell and cell constituent freeze-drying: fundamentals and principles
TH40952A (th) การเก็บรักษาสารละลายและสารแขวนลอยชีวภาพที่ว่องไวด้วยชั้นในระยะยาวที่วัดได้

Legal Events

Date Code Title Description
PA0105 International application

St.27 status event code: A-0-1-A10-A15-nap-PA0105

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

R18-X000 Changes to party contact information recorded

St.27 status event code: A-3-3-R10-R18-oth-X000

A201 Request for examination
P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PA0201 Request for examination

St.27 status event code: A-1-2-D10-D11-exm-PA0201

E701 Decision to grant or registration of patent right
PE0701 Decision of registration

St.27 status event code: A-1-2-D10-D22-exm-PE0701

GRNT Written decision to grant
PR0701 Registration of establishment

St.27 status event code: A-2-4-F10-F11-exm-PR0701

PR1002 Payment of registration fee

St.27 status event code: A-2-2-U10-U12-oth-PR1002

Fee payment year number: 1

PG1601 Publication of registration

St.27 status event code: A-4-4-Q10-Q13-nap-PG1601

FPAY Annual fee payment

Payment date: 20071023

Year of fee payment: 4

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 4

LAPS Lapse due to unpaid annual fee
PC1903 Unpaid annual fee

St.27 status event code: A-4-4-U10-U13-oth-PC1903

Not in force date: 20081110

Payment event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

PC1903 Unpaid annual fee

St.27 status event code: N-4-6-H10-H13-oth-PC1903

Ip right cessation event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

Not in force date: 20081110