KR100417261B1 - Oral composition containing bacteriocin - Google Patents
Oral composition containing bacteriocin Download PDFInfo
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- KR100417261B1 KR100417261B1 KR10-2000-0019977A KR20000019977A KR100417261B1 KR 100417261 B1 KR100417261 B1 KR 100417261B1 KR 20000019977 A KR20000019977 A KR 20000019977A KR 100417261 B1 KR100417261 B1 KR 100417261B1
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F28—HEAT EXCHANGE IN GENERAL
- F28D—HEAT-EXCHANGE APPARATUS, NOT PROVIDED FOR IN ANOTHER SUBCLASS, IN WHICH THE HEAT-EXCHANGE MEDIA DO NOT COME INTO DIRECT CONTACT
- F28D21/00—Heat-exchange apparatus not covered by any of the groups F28D1/00 - F28D20/00
- F28D21/0001—Recuperative heat exchangers
- F28D21/0012—Recuperative heat exchangers the heat being recuperated from waste water or from condensates
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F28—HEAT EXCHANGE IN GENERAL
- F28D—HEAT-EXCHANGE APPARATUS, NOT PROVIDED FOR IN ANOTHER SUBCLASS, IN WHICH THE HEAT-EXCHANGE MEDIA DO NOT COME INTO DIRECT CONTACT
- F28D1/00—Heat-exchange apparatus having stationary conduit assemblies for one heat-exchange medium only, the media being in contact with different sides of the conduit wall, in which the other heat-exchange medium is a large body of fluid, e.g. domestic or motor car radiators
- F28D1/02—Heat-exchange apparatus having stationary conduit assemblies for one heat-exchange medium only, the media being in contact with different sides of the conduit wall, in which the other heat-exchange medium is a large body of fluid, e.g. domestic or motor car radiators with heat-exchange conduits immersed in the body of fluid
- F28D1/04—Heat-exchange apparatus having stationary conduit assemblies for one heat-exchange medium only, the media being in contact with different sides of the conduit wall, in which the other heat-exchange medium is a large body of fluid, e.g. domestic or motor car radiators with heat-exchange conduits immersed in the body of fluid with tubular conduits
- F28D1/053—Heat-exchange apparatus having stationary conduit assemblies for one heat-exchange medium only, the media being in contact with different sides of the conduit wall, in which the other heat-exchange medium is a large body of fluid, e.g. domestic or motor car radiators with heat-exchange conduits immersed in the body of fluid with tubular conduits the conduits being straight
- F28D1/05316—Assemblies of conduits connected to common headers, e.g. core type radiators
- F28D1/05341—Assemblies of conduits connected to common headers, e.g. core type radiators with multiple rows of conduits or with multi-channel conduits combined with a particular flow pattern, e.g. multi-row multi-stage radiators
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Abstract
치주질환 원인균에 대해 감수성이 크고 항균 효과가 있는 천연 항생물질을 핵심성분으로 이용하여 제조됨으로써, 치주질환을 효과적으로 예방 및 치료할 수 있는 구강 조성물이 개시되어 있다. 본 발명에 따른 구강 조성물은, 박테리오신(Bacteriocin) 0.01∼1.0중량%, 후라보노이드 성분 0.1∼20중량%, 센탈라아시아티카 정량추출물 성분 0.01∼5중량%, 연마제 10∼30중량%, 물 20∼60중량%, 습윤제 1∼10중량%, 결속제 2∼10 중량%, 보존제 5∼10중량%, 향료 0.1∼5중량%, 계면활성제 2∼10중량%를 함유한다. 박테리오신을 함유함으로써, 치주병의 예방 및 치료에 대한 효능이 월등하고, 잇몸의 염증을 감소시켜 줄 뿐만 아니라 잇몸을 튼튼하게 하여 주어 세균 감염으로부터 저항할 수 있는 힘도 길러준다. 본 발명에 따른 구강 조성물을 사용하여 양치질을 할 경우, 치아미백 효과와 치석제거, 입냄새 제거, 잇몸질환 예방, 약한 잇몸을 건강하게 하는 효과를 동시에 얻을 수 있다.By using a natural antibiotic as a key component susceptible to the causative bacteria of periodontal disease and has an antimicrobial effect, oral compositions that can effectively prevent and treat periodontal disease have been disclosed. Oral composition according to the present invention, 0.01 to 1.0% by weight of bacteriocin, 0.1 to 20% by weight of flavonoid components, 0.01 to 5% by weight of Centala asiatica extract, 10 to 30% by weight of abrasive, 20 to 60 of water It contains by weight, 1 to 10% by weight wetting agent, 2 to 10% by weight binder, 5 to 10% by weight preservative, 0.1 to 5% by weight fragrance, and 2 to 10% by weight surfactant. By containing bacteriocin, it is excellent in the prevention and treatment of periodontal disease, not only reduces inflammation of the gums, but also strengthens the gums, thereby increasing the resistance to bacterial infection. When brushing teeth using the oral composition according to the present invention, the tooth whitening effect and calculus removal, bad breath removal, gum disease prevention, weak gums can be obtained at the same time healthy.
Description
본 발명은 구강 조성물에 관한 것으로, 더욱 상세하게는 치주질환 원인균에 대해 감수성이 크고 항균 효과가 있는 천연 항생물질인 박테리오신(Bacteriocin)을 핵심성분으로 이용하여 제조됨으로써, 치주질환을 효과적으로 예방 및 치료할 수 있는 구강 조성물에 관한 것이다.The present invention relates to an oral composition, and more particularly, by using a natural antibiotic bacteriocin (Bacteriocin) as a key ingredient susceptible to bacteria causing diseases of the periodontal disease, and effectively prevent and treat periodontal disease. Related to oral compositions.
치주병을 유발하는 주요한 병인균으로서는 Streptococcus mutans, Candida albicans, Actinomyces viscosus, Actinomyces naeslundii, actinomycetem comitans,Eikenella corrodens 등이 지목되고 있다.Major pathogens causing periodontal disease include Streptococcus mutans, Candida albicans, Actinomyces viscosus, Actinomyces naeslundii, actinomycetem comitans, and Eikenella corrodens.
이러한 원인균에 대항하는 유산균을 찾아내어 이 유산균이 분비하는 항생 물질을 추출 정제하면 치주질환에 효능 있는 천연항생물질을 얻을 수 있고, 이때 얻어지는 천연항생물질을 이용하여 구강 조성물을 제조하면 치주병을 예방 및 치료할 수 있을 것이다.Finding lactic acid bacteria against these causative bacteria and extracting and purifying the antibiotics secreted by the lactic acid bacteria can obtain natural antibiotics that are effective for periodontal disease.Preventing oral compositions using natural antibiotics obtained at this time prevents periodontal disease. And be curable.
본 발명은 상기와 같은 과제를 해결하기 위해 안출된 것으로, 본 발명의 목적은 치주질환 원인균에 대해 감수성이 크고 항균 효과가 있는 천연 항생물질인 박테리오신(Bacteriocin)을 핵심성분으로 이용하여 치주병을 예방 및 치료할 수 있는 구강 조성물을 제조하는데 있다.The present invention has been made to solve the above problems, the object of the present invention is to prevent periodontal disease by using a bacteriocin (natural bacteriocin) as a key ingredient susceptible to antibacterial causative bacteria And to prepare oral compositions that can be treated.
상기와 같은 목적을 달성하기 위해서, 본 발명은,In order to achieve the above object, the present invention,
박테리오신(Bacteriocin) 0.01∼1.0중량%, 후라보노이드 성분 0.1∼20중량%, 센탈라아시아티카 정량추출물 성분 0.01∼5중량%, 연마제 10∼30중량%, 물 20∼60중량%, 습윤제 1∼10중량%, 결속제 2∼10 중량%, 보존제 5∼10중량%, 향료 0.1∼5중량%, 계면활성제 2∼10중량%를 함유하는 것을 특징으로 하는 치주병 예방 및 치료용 구강 조성물을 제공한다.Bacteriocin 0.01 to 1.0% by weight, 0.1 to 20% by weight of flavonoid components, 0.01 to 5% by weight of Centala asiatica extract component, 10 to 30% by weight of abrasive, 20 to 60% by weight of water, 1 to 10% by weight of wetting agent It provides an oral composition for preventing and treating periodontal disease, which comprises%, 2 to 10% by weight of binder, 5 to 10% by weight of preservative, 0.1 to 5% by weight of perfume, and 2 to 10% by weight of surfactant.
이상에서 언급한 바와 같이, 본 발명에 따르면, 치주질환 원인균에 대해 감수성이 크고 항균 효과가 있는 천연 항생물질인 박테리오신(Bacteriocin)을 핵심성분으로 이용하여 치주병의 예방 및 치료에 대한 효능과 실효성이 월등한 구강 조성물을 제조한다.As mentioned above, according to the present invention, the bacteriocin (Bacteriocin), a natural antibiotic having susceptibility and antimicrobial effect to the causative agent of periodontal disease, is used as a key ingredient to prevent and treat periodontal disease. Prepare superior oral compositions.
이하, 본 발명에 따른 치주병 예방 및 치료용 구강 조성물에 대하여 상세하게 설명한다.Hereinafter, the oral composition for preventing and treating periodontal disease according to the present invention will be described in detail.
박테리오신(Bacteriocin)은 치주병을 유발하는 병인균에 대항하는 유산균이 분비하는 물질을 추출 정제하여 얻어지는 물질로서, 치아제지조직질환, 치은염, 치주증등 치주질환에 효과가 있으며, 항생물질이 아니면서도 잇몸의 염증을 감소시켜 줄 뿐만 아니라 잇몸을 튼튼하게 하여 주어 세균 감염으로부터 저항할 수 있게 해준다.Bacteriocin is a substance obtained by extracting and refining a substance secreted by lactic acid bacteria against pathogens that cause periodontal disease.It is effective in periodontal diseases such as tooth debris tissue disease, gingivitis, periodontitis, and it is not antibiotic Not only does it reduce inflammation, but it also strengthens the gums, helping to resist bacterial infections.
따라서, 본 발명에서는 이와같은 효능을 갖는 박테리오신(Bacteriocin)을 이용하여 치주병을 예방 및 치료할 수 있는 구강용 조성물을 만드는데, 이때 구강용 조성물은 박테리오신(Bacteriocin) 0.01∼1.0중량%, 후라보노이드 성분 0.1∼20중량%, 센탈라아시아티카 정량추출물 성분 0.01∼5중량%, 연마제 10∼30중량%, 물 20∼60중량%, 습윤제 1∼10중량%, 결속제 2∼10 중량%, 보존제 5∼10중량%, 향료 0.1∼5중량%, 계면활성제 2∼10중량%를 함유한다.Therefore, in the present invention, using the bacteriocin (Bacteriocin) having such an effect to create a composition for oral cavity that can prevent and treat periodontal disease, wherein the composition for the oral cavity is 0.01 to 1.0% by weight of the bacteriocin (Bacteriocin), 0.1 to flavonoid components 20% by weight, 0.01 to 5% by weight of Centala asiatica extract component, 10 to 30% by weight of abrasive, 20 to 60% by weight of water, 1 to 10% by weight of wetting agent, 2 to 10% by weight of binder, preservative 5 to 10 It contains weight%, fragrance 0.1-5 weight%, surfactant 2-10 weight%.
본 발명에 따른 구강용 조성물은 연마제 성분으로서 침강 실리카, 침강 탄산칼슘, 이 인산칼슘 또는 탄산수소나트륨 등에서 선택되는 물질을 함유한다.The composition for oral cavity according to the present invention contains a substance selected from precipitated silica, precipitated calcium carbonate, calcium phosphate, sodium hydrogen carbonate and the like as an abrasive component.
또한, 본 발명에 따른 구강용 조성물은 결속제 성분으로서, 결정성 실리카, 크산탄 검 또는 카르복시 메틸 셀룰로오스 등에서 선택되는 물질을 함유한다.In addition, the composition for oral cavity according to the present invention contains a substance selected from crystalline silica, xanthan gum or carboxymethyl cellulose as a binder component.
또한, 본 발명에 따른 구강용 조성물은 보존제 성분으로서, 안식향산 나트륨, 메틸 파라벤 또는 프로필 파라벤 등에서 선택된 물질을 함유한다.In addition, the composition for oral cavity according to the present invention contains a substance selected from sodium benzoate, methyl paraben or propyl paraben as a preservative component.
또한, 본 발명에 따른 조성물은 향료 성분으로서, 멘톨, 페퍼민트, 스피아민트, 후레쉬민트, 또는 이들의 조합에서 선택된 물질을 함유한다.In addition, the composition according to the present invention contains a substance selected from menthol, peppermint, spearmint, fresh mint, or a combination thereof as the perfume component.
본 발명에 사용되는 습윤제는 타제제들과 상용성이 좋고 특유의 자극적인 냄새가 없는 것들이어야 하며, 프로필렌 글리콜, 글리세린, 솔비톨, 폴리에틸렌 글리콜, 폴리프로필렌 글리콜, 마니톨, 자이리톨 또는 이들의 조합을 사용한다.Wetting agents used in the present invention should be compatible with other agents and have no peculiar irritating odor, using propylene glycol, glycerin, sorbitol, polyethylene glycol, polypropylene glycol, mannitol, xyitol or combinations thereof do.
또한, 본 발명에 따른 조성물은 계면활성제로서 알파-올레핀 설포네이트(α-OLEFFIN SULFONATE), 소디움 도데실 설페이트(SODIUM DODECYL SULFATE), 소디움도데실 벤젠 설포네이트(SODIUM DODECYL BENZENE SULFONATE), 폴리옥시 에틸렌 알킬 아릴 에테르(POLYOXYETHYLENE ALKYL ARYL ETHER), 탄소수 11-13를 갖고 EO 5-20몰을 갖는 2차-알코올 에톡실레이트(SECONDARY-ALCOHOL ETHOXYLATE), 탄소수 8-14를 갖고 EO 5-20몰을 갖는 1차-알코올 에톡실레이트(PRIMARY-ALCOHOL ETHOXYLATE), 폴리옥시 에틸렌 알킬 아릴 에테르(POLYOXYETHYLENE ALKYL ARYL ETHER)(여기에서 ALKYL기는 탄소수 8-12를 갖는 직쇠 사슬을 표시하며, ARYL기는 탄소수 6-12의 방향족기를 나타냄), 소디움 디옥틸 설포석시네이트(SODIUM DIOCTYL SULFOSUCCINATE)(상품명 AEROSOL OT 또는 CR-DOC70), 트윈류(TWEEN), 소르비탄 모노 올리에이트(SORBITAN MONO OLEATE(SPAN 80)), 소르비탄 모노 라우레이트(SORBITAN MONO LAURATE(SPAN 20)), 글리세린 모노 올리에이트(GLYCERIN MONO OLEATE(GMO)), 글리세린 모노 라우레이트(GLYCERIN MONO LAURATE(GML)) 등을 단독으로 또는 혼합하여 사용하였다.In addition, the composition according to the present invention is an alpha-olefin sulfonate (α-OLEFFIN SULFONATE), sodium dodecyl sulfate (SODIUM DODECYL SULFATE), sodium dodecyl benzene sulfonate (SODIUM DODECYL BENZENE SULFONATE), polyoxy ethylene alkyl POLYOXYETHYLENE ALKYL ARYL ETHER, SECONDARY-ALCOHOL ETHOXYLATE having 11-13 carbon atoms and 5-20 moles of EO, 1 having 5-20 moles of EO with 8-14 carbon atoms PRIMARY-ALCOHOL ETHOXYLATE, POLYOXYETHYLENE ALKYL ARYL ETHER, wherein the ALKYL group represents a straight chain having 8-12 carbon atoms, and the ARYL group is aromatic having 6-12 carbon atoms Group), sodium dioctyl sulfosuccinate (trade name AEROSOL OT or CR-DOC70), twins (TWEEN), sorbitan mono oleate (SORBITAN MONO OLEATE (SPAN 80)), sorbitan mono la Rate (SORBITAN MONO LAURATE (SPAN 20)), glycerol monooleate (GLYCERIN MONO OLEATE (GMO)), was used alone or in combination with glycerol monolaurate (GLYCERIN MONO LAURATE (GML)) and the like.
하기 에서는 본 발명에 따른 실시예들의 조성에 대하여 간단하게 설명한다.The following briefly describes the composition of the embodiments according to the present invention.
〈실시 예 1〉<Example 1>
박테리오신(Bacteriocin) 0.01∼1.0gBacteriocin 0.01 ~ 1.0g
침강 실리카 10∼20g10-20 g of precipitated silica
솔비톨 1∼10gSorbitol 1-10g
사카린 나트륨 1∼10gSaccharin Sodium 1-10g
안식향산 나트륨 5∼10gSodium benzoate 5-10g
색소 1∼5g1 to 5 g of pigment
향료 0.1∼5g0.1-5g fragrance
크산탄 검 0.5∼3gXanthan gum 0.5-3g
소르비탄 모노 올리에이트 1∼5g1-5 g of sorbitan mono oleate
글리세린 모노 라우레이트 1∼5g1 to 5 g glycerin monolaurate
프로필렌 글리콜 1∼3g1 to 3 g of propylene glycol
물 적량Water quantity
합계 100g100 g in total
상기 실시예 1과 같은 조성으로 잇몸질환 예방용 및 치아미백 조성물을 만들 수 있다.By the composition as in Example 1 can be made for preventing gum disease and tooth whitening composition.
〈실시예 2〉<Example 2>
박테리오신(Bacteriocin) 0.01∼1.0gBacteriocin 0.01 ~ 1.0g
침강 탄산칼슘 10∼20gPrecipitated Calcium Carbonate 10-20g
센탈라 아시아티카 정량추출물 5∼100mgCentala asiatica fixed extract 5-100mg
자이리톨 1∼10gXyitol 1-10 g
사카린 나트륨 1∼10gSaccharin Sodium 1-10g
안식향산 나트륨 5∼10gSodium benzoate 5-10g
색소 1∼5g1 to 5 g of pigment
향료 0.1∼5g0.1-5g fragrance
크산탄 검 0.5∼3gXanthan gum 0.5-3g
소디움 도데실 설페이트 1∼5gSodium Dodecyl Sulfate 1-5g
글리세린 모노 라우레이트 1∼5g1 to 5 g glycerin monolaurate
글리세린 1∼3gGlycerin 1-3g
물 적량Water quantity
합계 100g100 g in total
상기 실시예 2와 같은 조성으로 치아 미백 및 잇몸질환 치료용 조성물을 만들 수 있다.A composition for treating tooth whitening and gum disease can be made with the same composition as in Example 2.
〈실시예 3〉<Example 3>
박테리오신(Bacteriocin) 0.01∼1.0gBacteriocin 0.01 ~ 1.0g
자이리톨 5∼10gXylitol 5-10g
에틸알콜 5∼15g5-15 g of ethyl alcohol
솔비톨 5∼15gSorbitol 5-15g
사카린 나트륨 10∼100mgSaccharin Sodium 10-100mg
소디움 모노플루오로포스페이트 500∼1000mgSodium monofluorophosphate 500-1000 mg
소디움 라우릴설페이트 100∼200mgSodium Lauryl Sulfate 100-200mg
폴리솔베이트 20 100∼1000mgPolysorbate 20 100-1000mg
페파민트 플레이버 10∼100mgPeppermint Flavor 10-100mg
소디움 벤조에이트 10∼100gSodium benzoate 10-100 g
정제수 적량Purified water
color 적량color quantity
합계 100g100 g in total
상기 실시예 3과 같은 조성으로 치아 미백 및 입냄새 제거효과와 치주염 예방 치료효과가 있는 구강용 조성물인 가글을 만들 수 있다.With the same composition as in Example 3, it is possible to make a gargle which is a composition for oral cavity having a tooth whitening and bad breath removal effect and periodontitis prevention treatment effect.
이상에서 언급한 바와 같이, 본 발명에 따른 구강용 조성물은, 박테리오신(Bacteriocin) 0.01∼1.0g을 함유하므로써, 치주병의 예방과 치료에 효과가 있으며, 잇몸의 염증을 감소시켜 줄 뿐만 아니라 잇몸을 튼튼하게 하여 주어 세균 감염으로부터 저항할 수 있는 힘도 길러준다. 또한, 식물추출물인 후라보노이드와 파네졸을 함유시켜 입안의 악취발생 방지효과와 발생된 입냄새를 제거하고, 센탈라 아시아티카 정량추출물을 함유하므로서 입안의 상처를 치료하는 효과를 동시에 제공하며, 여기에 마모제, 습윤제, 감미제, 결속제, 희석제, 보존제, 향료, 색소, 계면활성제, 물 등의 부형제와 보조제를 혼합하여 제조된다.As mentioned above, the composition for oral cavity according to the present invention, by containing 0.01 to 1.0g of bacteriocin, is effective in the prevention and treatment of periodontal disease, as well as reducing the inflammation of the gums, It strengthens and gives strength to resist bacterial infection. In addition, it contains the plant extracts flavonoids and panesol to remove the bad smell in the mouth and to remove the bad smell, and to provide the effect of treating the wound in the mouth by containing the quanta extract of Centala asiatica, It is prepared by mixing excipients such as abrasives, wetting agents, sweeteners, binders, diluents, preservatives, flavoring agents, pigments, surfactants, water and the like.
그러므로, 본 발명에 따른 구강 조성물을 사용하여 양치질을 할 경우, 기존의 잇몸 질환 구강용 조성물과는 달리, 치아미백 효과와 치석제거, 입냄새 제거, 치주염 예방 및 치료, 약한 잇몸을 건강하게 하는 효과를 동시에 얻을 수 있다.Therefore, when brushing teeth using the oral composition according to the present invention, unlike the existing composition for oral gum disease, tooth whitening effect and tartar removal, bad breath removal, periodontitis prevention and treatment, weak gum health Can be obtained simultaneously.
상기에서는 본 발명의 바람직한 실시예를 참조하여 설명하였지만, 해당기술 분야의 숙련된 당업자는 하기의 특허 청구의 범위에 기재된 본 발명의 사상 및 영역으로부터 벗어나지 않는 범위내에서 본 발명을 다양하게 수정 및 변경시킬 수 있음을 이해할 수 있을 것이다.Although described above with reference to a preferred embodiment of the present invention, those skilled in the art will be variously modified and changed within the scope of the invention without departing from the spirit and scope of the invention described in the claims below. I can understand that you can.
Claims (3)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR10-2000-0019977A KR100417261B1 (en) | 2000-04-17 | 2000-04-17 | Oral composition containing bacteriocin |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR10-2000-0019977A KR100417261B1 (en) | 2000-04-17 | 2000-04-17 | Oral composition containing bacteriocin |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20010096066A KR20010096066A (en) | 2001-11-07 |
| KR100417261B1 true KR100417261B1 (en) | 2004-02-05 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR10-2000-0019977A KR100417261B1 (en) | 2000-04-17 | 2000-04-17 | Oral composition containing bacteriocin |
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| Country | Link |
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| KR (1) | KR100417261B1 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014017724A1 (en) * | 2012-07-25 | 2014-01-30 | 오스템임플란트 주식회사 | Compound for keeping teeth whitened for preventing tooth discoloration and staining |
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|---|---|---|---|---|
| US4318906A (en) * | 1979-06-25 | 1982-03-09 | Establissement Rinrone | Medicinal composition for external use for treating wounds |
| JPS5913721A (en) * | 1982-07-15 | 1984-01-24 | Tsurui Yakuhin Kogyo Kk | Agent for suppressing formation of bacterial plaque on tooth |
| JPH01121218A (en) * | 1987-11-04 | 1989-05-12 | Ikeda Mohandou:Kk | Cream for external use for remedy of dermatic disease |
| KR930002265A (en) * | 1991-07-06 | 1993-02-22 | 유청석 | Artificial marble using bio-ceramic and coated glass and its manufacturing method |
| KR0119269B1 (en) * | 1993-09-02 | 1997-10-17 | 최근선 | Plaque disclosing agent |
| KR980008207A (en) * | 1996-07-25 | 1998-04-30 | 성재갑 | Composition for promoting oral hygiene |
| US5840281A (en) * | 1993-01-07 | 1998-11-24 | Colgate Palmolive Company | Oral composition |
| KR0158048B1 (en) * | 1995-11-02 | 1998-12-01 | 이은선 | Tooth brushing components for mouth sanitary using bacteriosin |
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Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4318906A (en) * | 1979-06-25 | 1982-03-09 | Establissement Rinrone | Medicinal composition for external use for treating wounds |
| JPS5913721A (en) * | 1982-07-15 | 1984-01-24 | Tsurui Yakuhin Kogyo Kk | Agent for suppressing formation of bacterial plaque on tooth |
| JPH01121218A (en) * | 1987-11-04 | 1989-05-12 | Ikeda Mohandou:Kk | Cream for external use for remedy of dermatic disease |
| KR930002265A (en) * | 1991-07-06 | 1993-02-22 | 유청석 | Artificial marble using bio-ceramic and coated glass and its manufacturing method |
| US5840281A (en) * | 1993-01-07 | 1998-11-24 | Colgate Palmolive Company | Oral composition |
| KR0119269B1 (en) * | 1993-09-02 | 1997-10-17 | 최근선 | Plaque disclosing agent |
| KR0158048B1 (en) * | 1995-11-02 | 1998-12-01 | 이은선 | Tooth brushing components for mouth sanitary using bacteriosin |
| KR980008207A (en) * | 1996-07-25 | 1998-04-30 | 성재갑 | Composition for promoting oral hygiene |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014017724A1 (en) * | 2012-07-25 | 2014-01-30 | 오스템임플란트 주식회사 | Compound for keeping teeth whitened for preventing tooth discoloration and staining |
Also Published As
| Publication number | Publication date |
|---|---|
| KR20010096066A (en) | 2001-11-07 |
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