KR100384538B1 - A compound for disinfecting and washing a baby articles such as a nursing bottle - Google Patents

Abstract

The present invention relates to a sterile detergent composition, and more particularly, to a detergent composition containing a sterilization function to effectively remove or prevent bacteria or microorganisms that are native to baby products such as baby bottles and nipples.

The sterilizing and cleaning composition of the present invention comprises (1) 0.1 to 0.15 wt% of 2,4,4-trichloro-2-hydroxydiphenyl ether [2,4,4-trichloro-2-hydroxydiphenyl ether] as a sterilizing agent; (2) 6.8 wt% of polyoxyethylene (20) sorbitan monolaurate] as a surfactant that can be added to food; (3) 1% by weight of 95% fermented ethanol; (4) 0.2% by weight of sodium carboxymethyl cellulose; And (5) 91.9 to 91.85% by weight of purified water.

Description

A COMPOUND FOR DISINFECTING AND WASHING A BABY ARTICLES SUCH AS A NURSING BOTTLE}

The present invention relates to a sterile detergent composition, and more particularly, to a detergent composition containing a sterilization function to effectively remove or prevent bacteria or microorganisms that are native to baby products such as baby bottles and nipples.

Bacteria and microorganisms live in public homes and public places, causing many diseases. Therefore, in order to remove such bacteria and prevent microorganisms, Rox, which is a chlorine disinfectant, has been commonly used as a disinfectant. This lacx exhibits strong sterilizing power due to its sterilization and deodorizing effect by generator oxygen generated from hypochlorous acid.

However, these Lactose fungicides are harmful to the skin due to their high alkalinity, and the chlorine odor generated during use has anxiety about human safety, so they are well used for sterilizing and disinfecting baby products such as baby bottles and nipples. It doesn't work.

In addition, natural disinfection methods such as daylight and boil, which have been used for a long time, are cumbersome and time-consuming, and have a high possibility of re-contamination when cooled and concerned about the occurrence of environmental hormones.

The present invention is directed to solving this problem of the prior art and meeting the technical demands at hand.

That is, an object of the present invention is to provide a sterilizing and cleaning composition which is not only harmless to the human body but also can effectively remove bacteria and microorganisms.

Other objects and advantages of the invention will be described below and will be appreciated by the practice of the invention. Furthermore, the objects and advantages of the present invention can be realized by means and combinations indicated in the appended claims.

In order to achieve the above object, one aspect of the sterilizing and cleaning composition according to the present invention is (1) 0.1 to 5% by weight of a fungicide, which is harmless to the human body and has excellent function of inhibiting microorganisms; (2) 5 to 10% by weight of surfactant that can be added to food; (3) 1 to 40% by weight of ethyl alcohol; (4) 0.2-10% by weight of cellulose; And (5) 30 to 92% by weight of purified water.

In addition, the sterilizing and cleaning composition of the present invention may further comprise 0.5 to 10% by weight of propylene glycol.

The fungicide

(a) 5-amino-1,3-bis (2-ethylhexyl) -5-methyl-hexahydropyrimidine [5-amino-1,3-bis (2-ethylhexyl) -5-methyl-hexahydropyrimidine]

(b) 1-phenoxypropan-2-ol [1-phenoxypropan-2-ol]

(c) α-hydroxypropionic acid

(d) dehydroacetic acid

(e) 3-iodopropargyl-N-butylcarbamate

(f) methyl-N-benzimidazol-2-ylcarbamate

(g) 1-hydroxy-4-methyl-6- (2,4,4-trimethyl-pentyl) -2 (1H) pyridoneethanolamine salt [1-hydroxy-4-methyl-6- (2,4 , 4-trimethyl-phentyl) -2 (1H) pyridone ethanolamine salt]

(h) sodium 2-pyrinethiol-1-oxide

(i) zinc-bis- (2-pyridine-thiol-1-oxide)

(j) diodomethyl-ρ-tolylsulphone and

(k) any one selected from the group consisting of 2,4,4-trichloro-2'-hydroxydiphenyl ether [2,4,4-trichloro-2'-hydroxydiphenyl ether].

In addition, the surfactant is

(a) sodium lauryl eher ethoxy sulfate

(b) sodium lauryl sulfate (= dodecyl sodium sulfate)

(c) polyoxyethylene (80) sorbitan monolaurate (= Polysorbate 80) [polyoxyethylene (80) sorbitan monolaurate]

(d) polyoxyethylene (20) sorbitan monolaurate (= Polysorbate 20) [polyoxyethylene (20) sorbitan monolaurate]

(e) coconut fatty acids and

(f) any one selected from the group consisting of sucrose fatty acid esters.

The cellulose is preferably sodium carboxymethyl cellulose.

Sterilization and cleaning composition as another aspect of the present invention for achieving the above object is (1) 2,4,4-trichloro-2-hydroxydiphenyl ether [2,4,4-trichloro-2 as a bactericide; -hydroxydiphenyl ether] 0.1 to 0.15 wt%; (2) 6.8 wt% of polyoxyethylene (20) sorbitan monolaurate] as a surfactant that can be added to food; (3) 1% by weight of 95% fermented ethanol; (4) 0.2% by weight of sodium carboxymethyl cellulose; And (5) 91.9 to 91.85% by weight of purified water.

The fungicide is a substance having a strong bactericidal effect by inhibiting the action of each enzyme and inhibiting the synthesis of APT to prevent microorganisms even at low concentrations. The ethyl alcohol has a bactericidal action due to coagulation properties of proteins, It can also be used as a solvent by dissolving organic compounds and inorganic salts. Therefore, in the present invention, ethyl alcohol is used as an emulsifier to solubilize the fungicide and used as an antibacterial adjuvant. The cellulose swells when immersed in water. Since it has a property, it is used for the thickening effect of increasing the viscosity of the composition of the present invention by using this property. In addition, since the propylene glycol has a sticky property and wettability, it is generally used as a humectant, cosmetic, etc. Or as a drying inhibitor in foods. Cleaning of the Invention When using the composition, the propylene glycol is used as a protective material to prevent damage to the outer skin of the hand that is a direct contact. That is, it is used as a protecting agent to give moisturizing effect to hands.

Hereinafter, preferred embodiments of the present invention will be described in detail.

Example 1

0.2% by weight of 5-amino-1,3-bis (2-ethylhexyl) -5-methyl-hexahydropyrimidine as a bactericide and 10% by weight of sodium lauryl sulfate (= dodecyl sodium sulfate) as a surfactant; Ethanol 15% by weight; 0.7 wt% of sodium carboxymethyl cellulose, 0.5 wt% of propylene glycol, and 73.6 wt% of purified water (H ₂ O) were combined to prepare a sterilizing and cleaning composition.

Example 2

0.5% by weight of 1-phenoxypropan-2-ol as a bactericide and 10% by weight of sodium lauryl ether ethoxy sulfate as a surfactant; Ethanol 10% by weight; 0.4 wt% sodium carboxymethyl cellulose, 0.7 wt% propylene glycol, and 78.4 wt% purified water (H ₂ O) were combined to prepare a sterilizing and cleaning composition.

Example 3

5.0 wt% α-hydroxy-propionic acid as a bactericide and 8.0 wt% polysorbate 80 [= polyoxyethylene (80) sorbitan monolaurate] as a surfactant; Ethanol 30% by weight; 0.6 wt% sodium carboxymethyl cellulose, 10.0 wt% propylene glycol, and 46.4 wt% purified water (H ₂ O) were combined to prepare a sterilizing and cleaning composition.

Example 4

2.0 wt% of 3-iodopropargyl-N-butylcarbamate as a fungicide, 8.0 wt% of polysorbate 20 [= polyoxyethylene (20) sorbitan monolaurate] as a surfactant; Ethanol 40.0 wt%; 10.0% by weight of sodium carboxymethyl cellulose, 8.0% by weight of propylene glycol and 32.0% by weight of purified water (H ₂ O) were combined to prepare a sterilizing and cleaning composition.

Example 5

0.2% by weight of methyl-N-benzimidazol-2-yl carbamate as a bactericide and 10.0% by weight of coconut fatty acid as a surfactant; Ethanol 30.0 wt%; 5.0 wt% sodium carboxymethyl cellulose, 8.0 wt% propylene glycol and 46.8 wt% purified water (H ₂ O) were blended to prepare a sterilizing and cleaning composition.

Example 6

0.5% by weight of 1-hydroxy-4-methyl-6- (2,4,4-trimethyl-phentyl) -2 (1H) pyridone ethanol amine salt as a fungicide, 6.0% by weight of sucrose fatty acid ester as a surfactant; Ethanol 20.0 wt%; 1.0% by weight of sodium carboxymethyl cellulose, 10.0% by weight of propylene glycol and 62.5% by weight of purified water (H ₂ O) were combined to prepare a sterilizing and cleaning composition.

Example 7

0.3 wt% of 1-sodium-2-pyrinethiol-1-oxide as a bactericide, and 10.0 wt% of sodium lauryl sulfate (= dodecyl sodium sulfate) as a surfactant; Ethanol 20.0 wt%; 0.7 wt% sodium carboxymethyl cellulose, 7.0 wt% propylene glycol and 62.0 wt% purified water (H ₂ O) were combined to prepare a sterilizing and cleaning composition.

Example 8

0.3 wt% zinc-bis- (2-pyridine-thiol-1-oxide) as a bactericide and 5.0 wt% coconut fatty acid as a surfactant; Ethanol 10.0 wt%; 8.0 wt% sodium carboxymethyl cellulose, 10.0 wt% propylene glycol and 66.7 wt% purified water (H ₂ O) were blended to prepare a sterilizing and cleaning composition.

Example 9

0.4 wt% of diiodomethyl-ρ-tolylsulphone as fungicide, 7.0 wt% of polysorbate 20 [= polyoxyethylene (20) sorbitan monolaurate) as surfactant; Ethanol 20.0 wt%; 3.0 wt% sodium carboxymethyl cellulose, 5.0 wt% propylene glycol and 64.6 wt% purified water (H ₂ O) were combined to prepare a sterilizing and cleaning composition.

Example 10

0.5% by weight of 2,4,4-trichloro-2'-hydroxyldiphenyl ether as a fungicide, 10.0% by weight of polysorbate 80 [= polyoxyethylene (80) sorbitan monolaurate) as a surfactant; Ethanol 10.0 wt%; 8.0 wt% sodium carboxymethyl cellulose, 5.0 wt% propylene glycol and 66.5 wt% purified water (H ₂ O) were blended to prepare a sterilizing and cleaning composition.

Example 11

0.1 to 0.15% by weight of 2,4,4-trichloro-2-hydroxydiphenyl ether as a fungicide; 6.8% by weight of polyoxyethylene (20) sorbitan monolaurate as a surfactant which can be added to foods; 1% by weight of 95% fermented ethanol; 0.2% by weight sodium carboxymethyl cellulose; And 91.9 to 91.85% by weight of purified water were combined to prepare a sterilizing and cleaning composition.

<Test Example 1>

E. coli (Escherichia coli ATCC 25922), Staphylococcus aureus (Staphylococcusaureus ATCC 6538), Streptococcus pneumoniae (Klebsiella pneumoniae ATCC 4352), bacteria that are easily found in everyday life to confirm the bactericidal effect of the sterilizing and cleaning composition prepared in the present invention, Typhoid cocci (Salmonella typhimurium KCTC 1925) was selected.

After diluting and suspending the sterilizing and cleaning composition of Examples 1 to 10 by 10 times in water, and suspending E. coli, Staphylococcus aureus, pneumococci and typhoid cocci of a certain number of bacteria in this suspension, 1 minute, 10 minutes After dispensing in a sterile culture dish, the number of colonies shown by measuring the number of colonies in the container was measured and the sterilization power was measured, and the measurement results are shown in Table 1 below.

Strain Initial bacterial count (bacterial count / ml) Number of bacteria after contact % Reduction 1 minute 10 minutes Example 1 Escherichia coli 4.3 × 10 ⁶ 〈10 〈10 99.9 Staphylococcus aureus 3.8 × 10 ⁶ 〈10 〈10 99.9 Pneumococcal 4.0 × 10 ⁶ 〈10 〈10 99.9 Typhoid bacteria 3.4 × 10 ⁶ 〈10 〈10 99.9 Example 2 Escherichia coli 4.3 × 10 ⁶ 〈10 〈10 99.9 Staphylococcus aureus 3.8 × 10 ⁶ 〈10 〈10 99.9 Pneumococcal 4.0 × 10 ⁶ 〈10 〈10 99.9 Typhoid bacteria 3.4 × 10 ⁶ 〈10 〈10 99.9 Example 3 Escherichia coli 4.3 × 10 ⁶ 〈10 〈10 99.9 Staphylococcus aureus 3.8 × 10 ⁶ 〈10 〈10 99.9 Pneumococcal 4.0 × 10 ⁶ 〈10 〈10 99.9 Typhoid bacteria 3.4 × 10 ⁶ 〈10 〈10 99.9 Example 4 Escherichia coli 4.3 × 10 ⁶ 〈10 〈10 99.9 Staphylococcus aureus 3.8 × 10 ⁶ 〈10 〈10 99.9 Pneumococcal 4.0 × 10 ⁶ 〈10 〈10 99.9 Typhoid bacteria 3.4 × 10 ⁶ 〈10 〈10 99.9 Example 5 Escherichia coli 4.3 × 10 ⁶ 〈10 〈10 99.9 Staphylococcus aureus 3.8 × 10 ⁶ 〈10 〈10 99.9 Pneumococcal 4.0 × 10 ⁶ 〈10 〈10 99.9 Typhoid bacteria 3.4 × 10 ⁶ 〈10 〈10 99.9

Strain Initial bacterial count (bacterial count / ml) Number of bacteria after contact % Reduction 1 minute 10 minutes Example 6 Escherichia coli 4.3 × 10 ⁶ 〈10 〈10 99.9 Staphylococcus aureus 3.8 × 10 ⁶ 〈10 〈10 99.9 Pneumococcal 4.0 × 10 ⁶ 〈10 〈10 99.9 Typhoid bacteria 3.4 × 10 ⁶ 〈10 〈10 99.9 Example 7 Escherichia coli 4.3 × 10 ⁶ 〈10 〈10 99.9 Staphylococcus aureus 3.8 × 10 ⁶ 〈10 〈10 99.9 Pneumococcal 4.0 × 10 ⁶ 〈10 〈10 99.9 Typhoid bacteria 3.4 × 10 ⁶ 〈10 〈10 99.9 Example 8 Escherichia coli 4.3 × 10 ⁶ 〈10 〈10 99.9 Staphylococcus aureus 3.8 × 10 ⁶ 〈10 〈10 99.9 Pneumococcal 4.0 × 10 ⁶ 〈10 〈10 99.9 Typhoid bacteria 3.4 × 10 ⁶ 〈10 〈10 99.9 Example 9 Escherichia coli 4.3 × 10 ⁶ 〈10 〈10 99.9 Staphylococcus aureus 3.8 × 10 ⁶ 〈10 〈10 99.9 Pneumococcal 4.0 × 10 ⁶ 〈10 〈10 99.9 Typhoid bacteria 3.4 × 10 ⁶ 〈10 〈10 99.9 Example 10 Escherichia coli 4.3 × 10 ⁶ 〈10 〈10 99.9 Staphylococcus aureus 3.8 × 10 ⁶ 〈10 〈10 99.9 Pneumococcal 4.0 × 10 ⁶ 〈10 〈10 99.9 Typhoid bacteria 3.4 × 10 ⁶ 〈10 〈10 99.9

<Test Example 2>

E. coli (Escherichia coli ATCC 25922), Staphylococcus aureus (Staphylococcusaureus ATCC 6538), Streptococcus pneumoniae (Klebsiella pneumoniae ATCC 4352), bacteria that are easily found in everyday life to confirm the bactericidal effect of the sterilizing and cleaning composition prepared in the present invention, Typhoid cocci (Salmonella typhimurium KCTC 1925) was selected.

After diluting and suspending the sterilizing and cleaning composition of Example 11 in water ten times, and suspending E. coli, Staphylococcus aureus, pneumococci, typhoid cocci of a certain number of bacteria in this suspension, 30 seconds, 1 minute, 5 minutes after After dispensing in a sterile culture dish, the number of colonies shown by measuring the number of colonies in the container was measured and the sterilization power was measured, and the measurement results are shown in Table 2 below.

(A) Escherichia coli division Incubation time Blank 30sec 1 mim 5min Bacteria Count (Bacterial Count / ml) 2.7 × 10 ⁵ 2.6 × 10 ⁵ 2.7 × 10 ⁵ Not detected Not detected Not detected % Reduction - 99.9 99.9 99.9

(B) Staphylococcus aureus

division Incubation time Blank 30sec 1 mim 5min Bacteria Count (Bacterial Count / ml) 3.3 × 10 ⁵ 3.3 × 10 ⁵ 3.2 × 10 ⁵ Not detected Not detected Not detected % Reduction - 99.9 99.9 99.9

(C) typhoid bacteria

division Incubation time Blank 30sec 1 mim 5min Bacteria Count (Bacterial Count / ml) 1.8 × 10 ⁵ 1.8 × 10 ⁵ 1.7 × 10 ⁵ Not detected Not detected Not detected % Reduction - 99.9 99.9 99.9

(D) pneumococci

division Incubation time Blank 30sec 1 mim 5min Bacteria Count (Bacterial Count / ml) 3.6 × 10 ⁵ 3.5 × 10 ⁵ 3.6 × 10 ⁵ Not detected Not detected Not detected % Reduction - 99.9 99.9 99.9

As can be seen from Table 1 and Table 2, the cleaning composition of the present invention showed a strong bactericidal power against bacteria commonly found in daily life.

The present invention is not limited to the above-described embodiments, and various modifications and variations are made by those skilled in the art within the equivalent scope of the technical concept of the present invention and the claims to be described below. Of course it is possible.

The cleaning composition of the present invention exhibits a strong bactericidal effect against E. coli, Staphylococcus aureus, typhoid bacteria, pneumococci, and the like, which are commonly encountered in daily life, and is harmless to the human body so that it can be applied to infant products such as baby bottles and nipples.

Claims (6)

(1) 0.1 to 5% by weight of a fungicide harmless to human body and excellent in blocking microorganisms; (2) 5 to 10% by weight of surfactant that can be added to food; (3) 1 to 40% by weight of ethyl alcohol; (4) 0.2-10% by weight of cellulose; (5) A composition for sterilizing and cleaning baby products such as baby bottles and nipples containing 30 to 92% by weight of purified water. The method of claim 1, Propylene glycol (propylene glycol) 0.5 to 10% by weight of the composition for disinfecting and cleaning baby products, such as a baby bottle, nipple further comprising. The method of claim 2, The fungicide (a) 5-amino-1,3-bis (2-ethylhexyl) -5-methyl-hexahydropyrimidine (b) 1-phenoxypropan-2-ol (c) α-hydroxypropionic acid (d) dihydroacetic acid (e) 3-uridopropargyl-N-butylcarbamate (f) methyl-N-benzimidazol-2-ylcarbamate (g) 1-hydroxy-4-methyl-6- (2,4,4-trimethyl-pentyl) -2 (1H) pyridoneethanolamine salt (h) Sodium 윰 -2-pyrinethiol-1-oxide (i) zinc-bis- (2-pyridine-thiol-1-oxide) (j) diyodomethyl--tolylsulfone and (k) A composition for sterilizing and cleaning baby products such as baby bottles and nipples, which is any one selected from the group consisting of 2,4,4-trichloro-2'-hydroxydiphenyl ether. The method of claim 3, wherein The surfactant (a) Sodicurlauryl ether ethoxysulfate (b) Sodicullauryl sulfate (= dodecylsodisulphate) (c) polyoxyethylene (80) sorbitan monolaurate (= Polysorbate 80) (d) polyoxyethylene (20) sorbitan monolaurate (= Polysorbate 20) (e) palm fatty acids and (f) A composition for sterilizing and cleaning baby products such as baby bottles and nipples, which is any one selected from the group consisting of sucrose fatty acid esters. The method of claim 4, wherein The composition for disinfecting and cleaning baby products, such as baby bottles and nipples, characterized in that the cellulose is Sodium carboxymethyl cellulose. (1) 0.1 to 0.15% by weight of 2,4,4-trichloro-2-hydroxydiphenyl ether [2,4,4-trichloro-2-hydroxydiphenyl ether] as a bactericide; (2) 6.8 wt% of polyoxyethylene (20) sorbitan monolaurate] as a surfactant that can be added to food; (3) 1% by weight of 95% fermented ethanol; (4) 0.2% by weight of sodium carboxymethyl cellulose; And (5) A composition for sterilizing and cleaning baby products such as baby bottles and nipples, comprising 91.9 to 91.85% by weight of purified water.